#Чтение данных
AI_Tcells <- read_csv(
"../../raw_data/AI_Tcells_для ЕА - Sheet1.csv",
locale = locale(decimal_mark = ","), # указываем, что десятичный разделитель - запятая
show_col_types = FALSE
)
glimpse(AI_Tcells)
## Rows: 37,884
## Columns: 5
## $ ID <dbl> 50, 69, 58, 2, 52, 42, 44, 1, 31, 49, 34, 33, 8, 6, 46, 27,…
## $ Time_OS <dbl> 663, 503, 257, 434, 792, 363, 391, 786, 469, 447, 473, 559,…
## $ cGVHD_time <dbl> NA, 203, NA, 134, NA, NA, NA, NA, NA, 186, NA, NA, 203, 165…
## $ Names <chr> "+180_ПЕР.КРОВЬ/4_TFH", "+180_ПЕР.КРОВЬ/4_TFH", "+180_ПЕР.К…
## $ Abs_Value <dbl> 127.34533, 99.38984, 91.87249, 77.06436, 76.47210, 72.00345…
sum(is.na(AI_Tcells$Abs_Value))
## [1] 0
#Редактирование данных
AI_Tcells_data <- AI_Tcells %>%
mutate(Analysis_day = str_extract(Names, "^[^_]+")) %>% # Извлекаем часть до первого "_"
mutate(Сell_population = str_extract(Names, "(?<=\\/).*")) %>% # Извлекаем все после "/"
select(ID, Analysis_day, Сell_population, everything()) %>% # Перемещаем извлеченные данные в начало
separate_rows(Analysis_day, sep = ",") %>% # Создаем новые строки, если несколько значений разделены запятыми
mutate(Analysis_day = str_trim(Analysis_day))
AI_Tcells_data <- AI_Tcells_data %>%
mutate(cGVHD_present = ifelse(is.na(AI_Tcells_data$cGVHD_time), 0, 1))
AI_Tcells_data <- AI_Tcells_data %>%
mutate(cGVHD_present = factor(cGVHD_present, levels = c(0, 1), labels = c("No", "Yes")))
AI_Tcells_data <- AI_Tcells_data %>%
mutate(across(c(Analysis_day, Сell_population), ~ factor(.)))
glimpse(AI_Tcells_data)
## Rows: 37,884
## Columns: 8
## $ ID <dbl> 50, 69, 58, 2, 52, 42, 44, 1, 31, 49, 34, 33, 8, 6, 46…
## $ Analysis_day <fct> +180, +180, +180, +180, +180, +180, +180, +180, +180, …
## $ Сell_population <fct> 4_TFH, 4_TFH, 4_TFH, 4_TFH, 4_TFH, 4_TFH, 4_TFH, 4_TFH…
## $ Time_OS <dbl> 663, 503, 257, 434, 792, 363, 391, 786, 469, 447, 473,…
## $ cGVHD_time <dbl> NA, 203, NA, 134, NA, NA, NA, NA, NA, 186, NA, NA, 203…
## $ Names <chr> "+180_ПЕР.КРОВЬ/4_TFH", "+180_ПЕР.КРОВЬ/4_TFH", "+180_…
## $ Abs_Value <dbl> 127.34533, 99.38984, 91.87249, 77.06436, 76.47210, 72.…
## $ cGVHD_present <fct> No, Yes, No, Yes, No, No, No, No, No, Yes, No, No, Yes…
AI_Tcells_filtered <- AI_Tcells_data %>%
mutate(
Analysis_time = ifelse(
str_detect(Analysis_day, "^ДЕНЬ\\sХРРТПХ\\s\\+180$"), cGVHD_time + 180,
ifelse(
str_detect(Analysis_day, "^ДЕНЬ\\sХРРТПХ\\s\\+90$"), cGVHD_time + 90,
ifelse(
str_detect(Analysis_day, "^ДЕНЬ\\sХРРТПХ\\s\\+60$"), cGVHD_time + 60,
ifelse(
str_detect(Analysis_day, "^ДЕНЬ\\sХРРТПХ\\s\\+30$"), cGVHD_time + 30,
ifelse(
str_detect(Analysis_day, "^ДЕНЬ\\sХРРТПХ$"), cGVHD_time,
ifelse(
str_detect(Analysis_day, "^\\+180$"), 180,
ifelse(
str_detect(Analysis_day, "^\\+90$"), 90,
ifelse(
str_detect(Analysis_day, "^\\+60$"), 60,
ifelse(
str_detect(Analysis_day, "^\\+30$"), 30,
ifelse(
str_detect(Analysis_day, "^\\+365$"), 365, NA_real_
)))))))))))
AI_Tcells_filtered <- AI_Tcells_filtered %>%
filter(Analysis_day != "+30" & Analysis_day != "+60")
AI_Tcells_filtered <- AI_Tcells_filtered %>%
filter(!(Analysis_time == 180 & !is.na(cGVHD_time) & cGVHD_time < 180))
AI_Tcells_filtered <- AI_Tcells_filtered %>%
select(ID, Time_OS, cGVHD_present, cGVHD_time, Analysis_day, Analysis_time, Сell_population, Abs_Value)
AI_Tcells_filtered <- AI_Tcells_filtered %>%
arrange(ID, Analysis_time)
AI_Tcells_filtered <- AI_Tcells_filtered %>%
mutate(across(c(Time_OS, cGVHD_time, Analysis_time), ~ factor(.)))
glimpse(AI_Tcells_filtered)
## Rows: 34,440
## Columns: 8
## $ ID <dbl> 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, …
## $ Time_OS <fct> 786, 786, 786, 786, 786, 786, 786, 786, 786, 786, 786,…
## $ cGVHD_present <fct> No, No, No, No, No, No, No, No, No, No, No, No, No, No…
## $ cGVHD_time <fct> NA, NA, NA, NA, NA, NA, NA, NA, NA, NA, NA, NA, NA, NA…
## $ Analysis_day <fct> +90, +90, +90, +90, +90, +90, +90, +90, +90, +90, +90,…
## $ Analysis_time <fct> 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90…
## $ Сell_population <fct> 4_TFH, 4_TH1, 4_TH17, 4_Th17TO1, 4_TH2, 4_TH22, 4+ (IM…
## $ Abs_Value <dbl> 45.32738173, 7.89113186, 14.20660985, 3.33781372, 7.56…
#Описательные статистики
statistics <- list(
`_Количество субъектов` = ~length(.x) %>% as.character(),
`_Количество (есть данные)` = ~sum(!is.na(.x)) %>% as.character(),
`_Нет данных` = ~sum(is.na(.x)) %>% as.character(),
`_Ср. знач.` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", mean(.x, na.rm = TRUE) %>% round(2) %>% as.character()),
`_Станд. отклон.` = ~ifelse(sum(!is.na(.x)) < 3, "Н/П*", sd(.x, na.rm = TRUE) %>% round(2) %>% as.character()),
`_95% ДИ для среднего` = ~{
n <- sum(!is.na(.x))
ifelse(n < 3, "Н/П*",
paste0(round(mean(.x, na.rm = TRUE) - 1.96 * sd(.x, na.rm = TRUE) / sqrt(n), 2), " - ", round(mean(.x, na.rm = TRUE) + 1.96 * sd(.x, na.rm = TRUE) / sqrt(n), 2))
)
},
`_мин. - макс.` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", paste0(min(.x, na.rm = TRUE) %>% round(2), " - ", max(.x, na.rm = TRUE) %>% round(2))),
`_Медиана` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", median(.x, na.rm = TRUE) %>% round(2) %>% as.character()),
`_Q1 - Q3` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", paste0(quantile(.x, 0.25, na.rm = TRUE) %>% round(2), " - ", quantile(.x, 0.75, na.rm = TRUE) %>% round(2)))
)
#AI_Tcells_filtered %>%
# select(`Analysis_day`, `Сell_population`, `cGVHD_present`, Abs_Value) %>%
#group_by(`Analysis_day`, `Сell_population`, `cGVHD_present`) %>%
#summarize(across(Abs_Value, statistics)) %>% # Применяем список statistics к Abs_Value
#pivot_longer(cols = -c(`Analysis_day`, `Сell_population`, `cGVHD_present`)) %>%
#separate(name, into = c("Variable", "Statistics"), sep = "__") %>%
#pivot_wider(names_from = c(cGVHD_present, Statistics), values_from = value) %>%
#arrange(Analysis_day, Сell_population) %>%
#flextable() %>%
#theme_box() %>%
#align(align = "center", part = "all") %>%
#merge_v(c("Analysis_day", "Сell_population"))
# Создаём функцию для t-теста
t_test_wrapper <- function(data, var) {
# Проверяем достаточно ли данных в каждой группе
n_yes <- sum(!is.na(data$Abs_Value[data$cGVHD_present == "Yes"]))
n_no <- sum(!is.na(data$Abs_Value[data$cGVHD_present == "No"]))
if(n_yes < 3 || n_no < 3) {
return("Н/П*")
}
# Выполняем t-тест
test_result <- try(
t.test(Abs_Value ~ cGVHD_present, data = data)$p.value,
silent = TRUE
)
if(inherits(test_result, "try-error")) {
return("Ошибка")
}
return(as.character(round(test_result, 4)))
}
# Сначала соберем все p-values в отдельный датафрейм
p_values_df <- AI_Tcells_filtered %>%
group_by(Analysis_day, Сell_population) %>%
summarise(
p_value = t_test_wrapper(cur_data(), Abs_Value),
.groups = "drop"
)
## Warning: There was 1 warning in `summarise()`.
## ℹ In argument: `p_value = t_test_wrapper(cur_data(), Abs_Value)`.
## ℹ In group 1: `Analysis_day = +180` and `Сell_population = 4_TFH`.
## Caused by warning:
## ! `cur_data()` was deprecated in dplyr 1.1.0.
## ℹ Please use `pick()` instead.
# Создаем вектор для хранения скорректированных p-values
p_values_df <- p_values_df %>%
mutate(
adj_p_value = p_value # Сначала копируем исходные p-values
)
# Находим индексы числовых p-values
numeric_indices <- !p_values_df$p_value %in% c("Н/П*", "Ошибка")
if(sum(numeric_indices) > 0) {
# Конвертируем в числовой формат только валидные p-values
numeric_p_values <- as.numeric(p_values_df$p_value[numeric_indices])
# Применяем коррекцию только к числовым значениям
adj_p_values <- p.adjust(numeric_p_values, method = "BH")
# Обновляем только числовые значения в столбце adj_p_value
p_values_df$adj_p_value[numeric_indices] <- as.character(round(adj_p_values, 4))
}
# Основной код для создания таблицы
result <- AI_Tcells_filtered %>%
select(`Analysis_day`, `Сell_population`, `cGVHD_present`, Abs_Value) %>%
group_by(`Analysis_day`, `Сell_population`, `cGVHD_present`) %>%
summarize(across(Abs_Value, statistics), .groups = "drop") %>%
pivot_longer(cols = -c(`Analysis_day`, `Сell_population`, `cGVHD_present`)) %>%
separate(name, into = c("Variable", "Statistics"), sep = "__") %>%
pivot_wider(names_from = c(cGVHD_present, Statistics), values_from = value) %>%
# Присоединяем p-values
left_join(p_values_df, by = c("Analysis_day", "Сell_population")) %>%
rename(
"t-test, p-value" = p_value,
"t-test, adj p-value (BH)" = adj_p_value
) %>%
# Создаём финальную таблицу
arrange(Analysis_day, Сell_population) %>%
flextable() %>%
theme_box() %>%
align(align = "center", part = "all") %>%
merge_v(c("Analysis_day", "Сell_population"))
# Выводим таблицу
result
Analysis_day | Сell_population | Variable | No_Количество субъектов | No_Количество (есть данные) | No_Нет данных | No_Ср. знач. | No_Станд. отклон. | No_95% ДИ для среднего | No_мин. - макс. | No_Медиана | No_Q1 - Q3 | Yes_Количество субъектов | Yes_Количество (есть данные) | Yes_Нет данных | Yes_Ср. знач. | Yes_Станд. отклон. | Yes_95% ДИ для среднего | Yes_мин. - макс. | Yes_Медиана | Yes_Q1 - Q3 | t-test, p-value | t-test, adj p-value (BH) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
+180 | 4_TFH | Abs_Value | 28 | 28 | 0 | 45.23 | 28.19 | 34.79 - 55.67 | 8.17 - 127.35 | 40.6 | 22.45 - 65.56 | 14 | 14 | 0 | 37.18 | 27.83 | 22.6 - 51.76 | 2.96 - 99.39 | 35.05 | 15.51 - 48.27 | 0.3868 | 0.6866 |
4_TH1 | Abs_Value | 28 | 28 | 0 | 30.97 | 28.29 | 20.5 - 41.45 | 7.26 - 139.21 | 21.63 | 12.61 - 40.09 | 14 | 14 | 0 | 25.29 | 17.73 | 16 - 34.58 | 2.75 - 63.56 | 21.81 | 11.79 - 31.97 | 0.4314 | 0.7016 | |
4_TH17 | Abs_Value | 28 | 28 | 0 | 16.23 | 10.05 | 12.51 - 19.95 | 2.89 - 50.55 | 15.11 | 10.46 - 18.16 | 14 | 14 | 0 | 21.45 | 18.56 | 11.73 - 31.17 | 4.26 - 64.57 | 14.3 | 7.63 - 31.94 | 0.3393 | 0.6781 | |
4_Th17TO1 | Abs_Value | 28 | 28 | 0 | 4.72 | 3.18 | 3.54 - 5.89 | 1.1 - 13.48 | 3.96 | 2.45 - 5.84 | 14 | 14 | 0 | 5.4 | 4.28 | 3.15 - 7.64 | 0.37 - 14.28 | 4.01 | 2.13 - 8.88 | 0.6048 | 0.7822 | |
4_TH2 | Abs_Value | 28 | 28 | 0 | 19.81 | 14.65 | 14.38 - 25.23 | 3.06 - 52.15 | 14.55 | 7.62 - 30.35 | 14 | 14 | 0 | 25.44 | 33.42 | 7.93 - 42.94 | 4.36 - 132.22 | 13.3 | 8.77 - 24.71 | 0.5558 | 0.7482 | |
4_TH22 | Abs_Value | 28 | 28 | 0 | 5.43 | 4.37 | 3.82 - 7.05 | 0.11 - 17.53 | 4.44 | 2.27 - 6.29 | 14 | 14 | 0 | 7.12 | 7.42 | 3.23 - 11.01 | 0.6 - 23.07 | 2.51 | 1.43 - 12.46 | 0.4431 | 0.7032 | |
4+ | Abs_Value | 28 | 28 | 0 | 86.07 | 70.15 | 60.08 - 112.05 | 5.3 - 282.24 | 67.56 | 40.39 - 98.89 | 14 | 14 | 0 | 127.74 | 115.12 | 67.43 - 188.04 | 30.9 - 465.64 | 81.58 | 54.97 - 183.63 | 0.2295 | 0.6781 | |
4+ (IM STAT) | Abs_Value | 28 | 28 | 0 | 76.11 | 63.83 | 52.47 - 99.75 | 4.58 - 261.9 | 59.63 | 31.36 - 88.74 | 14 | 14 | 0 | 111.92 | 111.9 | 53.3 - 170.54 | 31.06 - 463.87 | 67.8 | 49.95 - 149.55 | 0.282 | 0.6781 | |
4+226+ | Abs_Value | 28 | 28 | 0 | 240.03 | 119.69 | 195.69 - 284.36 | 82.61 - 581.74 | 237.99 | 154.89 - 305.8 | 14 | 14 | 0 | 253.52 | 138.82 | 180.79 - 326.24 | 59.38 - 494.52 | 233.24 | 142.9 - 349.53 | 0.759 | 0.884 | |
4+39+ | Abs_Value | 28 | 28 | 0 | 58.56 | 45.04 | 41.88 - 75.24 | 1.62 - 164.84 | 44.35 | 28.99 - 83.56 | 14 | 14 | 0 | 70.14 | 50.91 | 43.47 - 96.81 | 0.38 - 146.53 | 83.04 | 21.52 - 108.28 | 0.4776 | 0.7185 | |
4+DR+ | Abs_Value | 28 | 28 | 0 | 118.21 | 78.19 | 89.25 - 147.17 | 18.11 - 386.46 | 103.52 | 62.43 - 147.72 | 14 | 14 | 0 | 88.68 | 61.64 | 56.39 - 120.97 | 2.7 - 196.42 | 90.06 | 39.97 - 120.04 | 0.1915 | 0.6781 | |
4+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 88.95 | 59.1 | 67.06 - 110.84 | 12.4 - 216.52 | 71.92 | 38.42 - 131.56 | 14 | 14 | 0 | 124.6 | 89.68 | 77.62 - 171.58 | 21.15 - 336.65 | 103.12 | 48.41 - 181.86 | 0.1936 | 0.6781 | |
4+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 8.59 | 6.57 | 6.16 - 11.02 | 0.33 - 26.88 | 7.44 | 3.72 - 12.65 | 14 | 14 | 0 | 12.15 | 11.99 | 5.87 - 18.44 | 1.08 - 42.09 | 7.08 | 3.75 - 14.78 | 0.3144 | 0.6781 | |
4+PD-1+ | Abs_Value | 28 | 28 | 0 | 163.55 | 100.44 | 126.35 - 200.75 | 60.8 - 544 | 146.17 | 92.9 - 204.31 | 14 | 14 | 0 | 137.32 | 78.18 | 96.36 - 178.27 | 19.13 - 251.25 | 137.45 | 85.35 - 188.75 | 0.3595 | 0.6829 | |
4+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 82.11 | 47.24 | 64.61 - 99.61 | 24.66 - 231.24 | 70.6 | 42.83 - 113.14 | 14 | 14 | 0 | 69.48 | 41.05 | 47.97 - 90.98 | 11.98 - 141.31 | 71.58 | 41.53 - 92.15 | 0.379 | 0.6866 | |
4+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 81.44 | 60.21 | 59.14 - 103.75 | 23.47 - 312.76 | 70.14 | 36.23 - 104.1 | 14 | 14 | 0 | 67.84 | 41.86 | 45.91 - 89.77 | 6.97 - 118.9 | 74.09 | 34.46 - 107.46 | 0.3997 | 0.6866 | |
4+TIGIT+ | Abs_Value | 28 | 28 | 0 | 90.03 | 62.5 | 66.88 - 113.18 | 27.22 - 316.38 | 78.85 | 39.78 - 118.18 | 14 | 14 | 0 | 80 | 50.5 | 53.54 - 106.45 | 8.05 - 142.11 | 83.98 | 37.28 - 128.03 | 0.5796 | 0.7625 | |
4NV | Abs_Value | 28 | 28 | 0 | 47.92 | 50.96 | 29.04 - 66.79 | 1.38 - 219.79 | 32.76 | 17.69 - 57.58 | 14 | 14 | 0 | 68.98 | 57.36 | 38.93 - 99.03 | 8.01 - 221.84 | 63.72 | 22.76 - 100.68 | 0.2563 | 0.6781 | |
4NV(СТАР2) | Abs_Value | 28 | 28 | 0 | 41.99 | 45.17 | 25.26 - 58.72 | 1.11 - 184.63 | 28.89 | 15.07 - 54.98 | 14 | 14 | 0 | 64.13 | 53.04 | 36.35 - 91.92 | 7.33 - 199 | 55.39 | 24.35 - 92.65 | 0.1941 | 0.6781 | |
4NV_TH1 | Abs_Value | 28 | 28 | 0 | 2.34 | 3.55 | 1.02 - 3.65 | 0.01 - 18.64 | 1.69 | 0.55 - 2.22 | 14 | 14 | 0 | 5.4 | 7.87 | 1.28 - 9.52 | 0.26 - 31.18 | 3.5 | 0.99 - 5.44 | 0.1848 | 0.6781 | |
4NV_TH17 | Abs_Value | 28 | 28 | 0 | 1.43 | 1.4 | 0.91 - 1.95 | 0.17 - 5.2 | 0.84 | 0.43 - 2.12 | 14 | 14 | 0 | 1.76 | 1.66 | 0.89 - 2.63 | 0.15 - 6.65 | 1.37 | 0.68 - 2.26 | 0.5269 | 0.739 | |
4NV_Th17TO1 | Abs_Value | 28 | 28 | 0 | 0.16 | 0.19 | 0.09 - 0.23 | 0 - 0.76 | 0.09 | 0.04 - 0.17 | 14 | 14 | 0 | 0.44 | 0.69 | 0.08 - 0.8 | 0.03 - 2.7 | 0.2 | 0.1 - 0.46 | 0.1581 | 0.6781 | |
4NV_TH2 | Abs_Value | 28 | 28 | 0 | 10 | 10.71 | 6.03 - 13.97 | 0.32 - 42.08 | 5.32 | 1.9 - 16.43 | 14 | 14 | 0 | 6.01 | 4.03 | 3.9 - 8.12 | 0.9 - 15.34 | 4.93 | 3.44 - 7.26 | 0.0898 | 0.6781 | |
4NV_TH22 | Abs_Value | 28 | 28 | 0 | 0.12 | 0.13 | 0.07 - 0.17 | 0 - 0.47 | 0.05 | 0.03 - 0.19 | 14 | 14 | 0 | 0.2 | 0.22 | 0.08 - 0.31 | 0 - 0.85 | 0.16 | 0.05 - 0.24 | 0.2363 | 0.6781 | |
4NV+226+ | Abs_Value | 28 | 28 | 0 | 34.27 | 40.56 | 19.24 - 49.29 | 1.04 - 182.46 | 25.68 | 11.13 - 43.23 | 14 | 14 | 0 | 55.97 | 47.49 | 31.1 - 80.85 | 6.77 - 176.27 | 47.59 | 19.76 - 79.5 | 0.1569 | 0.6781 | |
4NV+39+ | Abs_Value | 28 | 28 | 0 | 1.13 | 1.41 | 0.61 - 1.66 | 0.01 - 6.53 | 0.59 | 0.27 - 1.45 | 14 | 14 | 0 | 2.25 | 2.81 | 0.78 - 3.72 | 0.05 - 10.36 | 1.6 | 0.35 - 2.53 | 0.1805 | 0.6781 | |
4NV+DR+ | Abs_Value | 28 | 28 | 0 | 3.59 | 4.26 | 2.02 - 5.17 | 0.18 - 18.97 | 2.07 | 0.83 - 4.89 | 14 | 14 | 0 | 3.51 | 3.73 | 1.56 - 5.47 | 0.16 - 12.36 | 1.95 | 1.19 - 4.3 | 0.9487 | 0.9711 | |
4NV+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 37.82 | 41.89 | 22.3 - 53.33 | 0.89 - 162.97 | 26.57 | 10.46 - 51.5 | 14 | 14 | 0 | 57.92 | 49.73 | 31.87 - 83.97 | 6.57 - 183.96 | 52.16 | 20.83 - 83.48 | 0.207 | 0.6781 | |
4NV+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 1.06 | 1.51 | 0.5 - 1.62 | 0.07 - 5.24 | 0.41 | 0.13 - 1.22 | 14 | 14 | 0 | 1.77 | 2.27 | 0.58 - 2.96 | 0.08 - 8.38 | 0.69 | 0.41 - 2.19 | 0.3061 | 0.6781 | |
4NV+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 2.19 | 2.63 | 1.22 - 3.16 | 0.07 - 10.74 | 1.21 | 0.51 - 2.14 | 14 | 14 | 0 | 2.94 | 3.29 | 1.22 - 4.67 | 0.26 - 11.91 | 1.3 | 0.73 - 4.66 | 0.4625 | 0.7142 | |
4NV+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 0.92 | 1.16 | 0.49 - 1.35 | 0.07 - 6.02 | 0.64 | 0.15 - 1.11 | 14 | 14 | 0 | 1.5 | 1.45 | 0.74 - 2.26 | 0.06 - 4.55 | 1.06 | 0.43 - 1.72 | 0.2059 | 0.6781 | |
4NV+PD1+ | Abs_Value | 28 | 28 | 0 | 3.11 | 3.54 | 1.8 - 4.42 | 0.15 - 16.77 | 2.1 | 0.94 - 3.82 | 14 | 14 | 0 | 4.44 | 4.28 | 2.2 - 6.69 | 0.49 - 15.18 | 2.53 | 1.15 - 6.58 | 0.3243 | 0.6781 | |
4NV+TIGIT+ | Abs_Value | 28 | 28 | 0 | 1.98 | 2.4 | 1.09 - 2.87 | 0.15 - 10.91 | 1.18 | 0.46 - 2.38 | 14 | 14 | 0 | 3.27 | 3.41 | 1.48 - 5.06 | 0.14 - 12.48 | 1.97 | 1.02 - 4.53 | 0.221 | 0.6781 | |
4ЕМ | Abs_Value | 28 | 28 | 0 | 27.44 | 62.36 | 4.35 - 50.54 | 0.05 - 337.94 | 15.05 | 5.39 - 24.18 | 14 | 14 | 0 | 8.4 | 8.82 | 3.77 - 13.02 | 0.17 - 25.86 | 5.24 | 1.79 - 9.96 | 0.1238 | 0.6781 | |
4ЕМ_TH1 | Abs_Value | 28 | 28 | 0 | 10.52 | 21.21 | 2.67 - 18.38 | 0 - 112.94 | 4.34 | 1.5 - 10.68 | 14 | 14 | 0 | 3.18 | 4.44 | 0.85 - 5.5 | 0.03 - 12.98 | 1.11 | 0.26 - 3.35 | 0.0886 | 0.6781 | |
4ЕМ_TH17 | Abs_Value | 28 | 28 | 0 | 0.03 | 0.05 | 0.01 - 0.05 | 0 - 0.18 | 0.01 | 0 - 0.03 | 14 | 14 | 0 | 0.07 | 0.16 | -0.01 - 0.15 | 0 - 0.59 | 0.01 | 0 - 0.04 | 0.3904 | 0.6866 | |
4ЕМ_Th17TO1 | Abs_Value | 28 | 28 | 0 | 0.51 | 0.93 | 0.16 - 0.86 | 0 - 4.85 | 0.2 | 0.07 - 0.57 | 14 | 14 | 0 | 0.19 | 0.22 | 0.08 - 0.31 | 0 - 0.66 | 0.13 | 0.03 - 0.23 | 0.0996 | 0.6781 | |
4ЕМ_TH2 | Abs_Value | 28 | 28 | 0 | 1.79 | 4.75 | 0.03 - 3.55 | 0 - 24.46 | 0.2 | 0.02 - 1.83 | 14 | 14 | 0 | 0.32 | 0.59 | 0.01 - 0.62 | 0.01 - 2.2 | 0.08 | 0.04 - 0.28 | 0.1176 | 0.6781 | |
4ЕМ_TH22 | Abs_Value | 28 | 28 | 0 | 0.01 | 0.02 | 0 - 0.02 | 0 - 0.11 | 0 | 0 - 0.01 | 14 | 14 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.05 | 0 | 0 - 0 | 0.4551 | 0.7131 | |
4ЕМ+226+ | Abs_Value | 28 | 28 | 0 | 131.59 | 96.96 | 95.68 - 167.5 | 29.52 - 477.35 | 86.56 | 66.35 - 180.01 | 14 | 14 | 0 | 105.55 | 69.84 | 68.96 - 142.13 | 22.39 - 224.92 | 90.27 | 45.45 - 150.7 | 0.3264 | 0.6781 | |
4ЕМ+39+ | Abs_Value | 28 | 28 | 0 | 36.82 | 35.18 | 23.79 - 49.85 | 0.88 - 146.09 | 23.82 | 17.36 - 48.28 | 14 | 14 | 0 | 39.21 | 29.01 | 24.01 - 54.41 | 0.25 - 83.93 | 40.64 | 10.33 - 58.8 | 0.8168 | 0.9094 | |
4ЕМ+DR+ | Abs_Value | 28 | 28 | 0 | 80.97 | 68.49 | 55.6 - 106.34 | 10.12 - 341.19 | 52.11 | 40.32 - 119.37 | 14 | 14 | 0 | 51.14 | 37.29 | 31.61 - 70.68 | 2.19 - 150.75 | 51.7 | 25.99 - 61.76 | 0.0754 | 0.6781 | |
4ЕМ+PD1-TIGIT- | Abs_Value | 28 | 28 | 0 | 26.19 | 17.91 | 19.56 - 32.83 | 2 - 69.84 | 21.04 | 12.78 - 37.04 | 14 | 14 | 0 | 28.45 | 24.11 | 15.82 - 41.08 | 2.07 - 74.3 | 23.78 | 8.55 - 37.9 | 0.76 | 0.884 | |
4ЕМ+PD1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 3.33 | 2.73 | 2.32 - 4.34 | 0.08 - 9.42 | 2.47 | 1.26 - 5.09 | 14 | 14 | 0 | 4.11 | 3.66 | 2.19 - 6.03 | 0.19 - 11.47 | 2.6 | 1.05 - 6.71 | 0.4911 | 0.7192 | |
4ЕМ+PD1+ | Abs_Value | 28 | 28 | 0 | 109.28 | 90.94 | 75.59 - 142.96 | 26.74 - 465.38 | 74.09 | 54.15 - 143.28 | 14 | 14 | 0 | 78.12 | 49.93 | 51.96 - 104.27 | 15.86 - 159.29 | 77.61 | 40.3 - 96.23 | 0.16 | 0.6781 | |
4ЕМ+PD1+TIGIT- | Abs_Value | 28 | 28 | 0 | 56.89 | 40.09 | 42.04 - 71.73 | 12.43 - 175.98 | 44.68 | 27.37 - 76.23 | 14 | 14 | 0 | 40.42 | 25.27 | 27.18 - 53.65 | 7.04 - 85.23 | 38.63 | 20.38 - 56.75 | 0.113 | 0.6781 | |
4ЕМ+PD1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 52.39 | 54.96 | 32.03 - 72.75 | 13.52 - 289.4 | 39.84 | 18.79 - 77.5 | 14 | 14 | 0 | 37.7 | 27.66 | 23.21 - 52.19 | 4.8 - 89.86 | 29.72 | 15.62 - 55.48 | 0.2561 | 0.6781 | |
4ЕМ+TIGIT+ | Abs_Value | 28 | 28 | 0 | 55.72 | 55.87 | 35.03 - 76.42 | 14.57 - 292.02 | 40.91 | 19.91 - 84.16 | 14 | 14 | 0 | 41.81 | 29.93 | 26.13 - 57.49 | 6.19 - 95.58 | 35.76 | 16.71 - 61.83 | 0.2999 | 0.6781 | |
4ЕМTM | Abs_Value | 28 | 28 | 0 | 138.8 | 99.73 | 101.86 - 175.74 | 30.94 - 480.41 | 105.39 | 68.28 - 188.97 | 14 | 14 | 0 | 110.67 | 71.84 | 73.04 - 148.31 | 23.66 - 228.74 | 94.42 | 48.98 - 159.67 | 0.303 | 0.6781 | |
4СМ | Abs_Value | 28 | 28 | 0 | 61.75 | 37.84 | 47.73 - 75.77 | 13.26 - 146.46 | 52.11 | 30.84 - 91.37 | 14 | 14 | 0 | 76.5 | 55.02 | 47.68 - 105.32 | 10.54 - 214.21 | 63.18 | 36.55 - 115.1 | 0.378 | 0.6866 | |
4СМ(СТАР2) | Abs_Value | 28 | 28 | 0 | 47.2 | 26.48 | 37.4 - 57.01 | 7.82 - 107.45 | 43.92 | 23.6 - 62.8 | 14 | 14 | 0 | 58.39 | 51.76 | 31.28 - 85.51 | 8.04 - 200.31 | 44.16 | 28.4 - 63.93 | 0.4575 | 0.7142 | |
4СМ_TH1 | Abs_Value | 28 | 28 | 0 | 1.47 | 1.67 | 0.85 - 2.09 | 0.07 - 7.15 | 0.97 | 0.45 - 1.42 | 14 | 14 | 0 | 3.57 | 5.03 | 0.93 - 6.2 | 0.3 - 20.04 | 2.01 | 0.94 - 4 | 0.1503 | 0.6781 | |
4СМ_TH17 | Abs_Value | 28 | 28 | 0 | 7.3 | 4.88 | 5.49 - 9.1 | 1.27 - 20.38 | 6.35 | 3.64 - 9.25 | 14 | 14 | 0 | 9.16 | 7.08 | 5.46 - 12.87 | 2.38 - 28.22 | 8.46 | 3.19 - 12.75 | 0.3861 | 0.6866 | |
4СМ_Th17TO1 | Abs_Value | 28 | 28 | 0 | 0.49 | 0.49 | 0.31 - 0.67 | 0.04 - 2.29 | 0.34 | 0.2 - 0.55 | 14 | 14 | 0 | 0.96 | 1.18 | 0.34 - 1.58 | 0.04 - 4.47 | 0.57 | 0.24 - 0.97 | 0.1713 | 0.6781 | |
4СМ_TH2 | Abs_Value | 28 | 28 | 0 | 4.52 | 3.7 | 3.15 - 5.89 | 0.45 - 18.22 | 3.69 | 1.93 - 6.35 | 14 | 14 | 0 | 7.16 | 7.96 | 2.99 - 11.33 | 1.8 - 29.39 | 3.6 | 2.62 - 5.96 | 0.2551 | 0.6781 | |
4СМ_TH22 | Abs_Value | 28 | 28 | 0 | 0.64 | 0.59 | 0.43 - 0.86 | 0.02 - 2.89 | 0.47 | 0.28 - 0.88 | 14 | 14 | 0 | 1.13 | 1.03 | 0.59 - 1.67 | 0.08 - 3.27 | 0.91 | 0.44 - 1.5 | 0.1197 | 0.6781 | |
4СМ+226+ | Abs_Value | 28 | 28 | 0 | 43.71 | 25.43 | 34.29 - 53.13 | 7.56 - 105.79 | 39.19 | 22.71 - 57.23 | 14 | 14 | 0 | 54.63 | 48.32 | 29.32 - 79.94 | 7.28 - 188.86 | 41.68 | 27.29 - 61.77 | 0.4392 | 0.7016 | |
4СМ+39+ | Abs_Value | 28 | 28 | 0 | 13.31 | 11.75 | 8.96 - 17.66 | 0.11 - 41.64 | 9 | 5.26 - 21.33 | 14 | 14 | 0 | 20.63 | 22.13 | 9.04 - 32.22 | 0.05 - 75.65 | 13.68 | 6.29 - 27.45 | 0.2629 | 0.6781 | |
4СМ+DR+ | Abs_Value | 28 | 28 | 0 | 14.05 | 12.11 | 9.56 - 18.53 | 1.83 - 40.68 | 7.66 | 5.74 - 22.38 | 14 | 14 | 0 | 15.17 | 18.57 | 5.44 - 24.9 | 0.29 - 56.48 | 5.82 | 3.97 - 19.91 | 0.8402 | 0.9146 | |
4СМ+PD1-TIGIT- | Abs_Value | 28 | 28 | 0 | 15.05 | 9.37 | 11.58 - 18.52 | 2.82 - 32.52 | 13.06 | 6.32 - 25.05 | 14 | 14 | 0 | 22.08 | 26.2 | 8.35 - 35.8 | 3.91 - 99.16 | 13.5 | 6.88 - 21.33 | 0.3464 | 0.6781 | |
4СМ+PD1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 2.23 | 2.09 | 1.45 - 3 | 0.09 - 7.53 | 1.54 | 0.52 - 2.95 | 14 | 14 | 0 | 3.38 | 4.01 | 1.28 - 5.49 | 0.15 - 15.02 | 1.9 | 1.02 - 4.37 | 0.3251 | 0.6781 | |
4СМ+PD1+ | Abs_Value | 28 | 28 | 0 | 29.92 | 18.68 | 23 - 36.84 | 3.4 - 75.06 | 26.33 | 17.08 - 40.87 | 14 | 14 | 0 | 32.93 | 28.96 | 17.76 - 48.1 | 1.74 - 94.4 | 23.08 | 14.69 - 43.5 | 0.7278 | 0.8715 | |
4СМ+PD1+TIGIT- | Abs_Value | 28 | 28 | 0 | 11.7 | 7.17 | 9.05 - 14.36 | 2.06 - 26.13 | 9.96 | 6.8 - 14.44 | 14 | 14 | 0 | 12.4 | 10.65 | 6.83 - 17.98 | 1.38 - 31.91 | 8.2 | 4.81 - 16.08 | 0.8267 | 0.9094 | |
4СМ+PD1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 18.22 | 14.61 | 12.81 - 23.63 | 1.34 - 62.79 | 15.67 | 8.1 - 21.06 | 14 | 14 | 0 | 20.53 | 19.49 | 10.32 - 30.73 | 0.36 - 62.83 | 14.99 | 8.23 - 26.26 | 0.6996 | 0.8548 | |
4СМ+TIGIT+ | Abs_Value | 28 | 28 | 0 | 20.45 | 16.09 | 14.48 - 26.41 | 1.79 - 69.48 | 16.63 | 10.12 - 28.13 | 14 | 14 | 0 | 23.91 | 22.07 | 12.35 - 35.47 | 0.54 - 73.37 | 18.51 | 9.93 - 31.86 | 0.6073 | 0.7822 | |
4ТM_TH1 | Abs_Value | 28 | 28 | 0 | 12.31 | 11.97 | 7.87 - 16.74 | 1.94 - 55.53 | 9.77 | 3.97 - 14.73 | 14 | 14 | 0 | 6.96 | 3.66 | 5.04 - 8.88 | 1.3 - 14.41 | 7.44 | 4.52 - 8.95 | 0.0368 | 0.6781 | |
4ТM_TH17 | Abs_Value | 28 | 28 | 0 | 6.86 | 4.9 | 5.04 - 8.67 | 0.9 - 22.86 | 5.87 | 3.72 - 8.31 | 14 | 14 | 0 | 9.69 | 12.24 | 3.28 - 16.1 | 0.94 - 44.13 | 5.29 | 2.16 - 8.55 | 0.4184 | 0.6976 | |
4ТM_Th17TO1 | Abs_Value | 28 | 28 | 0 | 3.12 | 2.5 | 2.19 - 4.05 | 0.79 - 10.52 | 2.39 | 1.52 - 3.62 | 14 | 14 | 0 | 3.02 | 2.9 | 1.5 - 4.54 | 0.28 - 10.5 | 2.48 | 1.05 - 3.28 | 0.9136 | 0.956 | |
4ТM_TH2 | Abs_Value | 28 | 28 | 0 | 2.51 | 1.95 | 1.79 - 3.24 | 0.6 - 8.26 | 1.85 | 1.07 - 3.5 | 14 | 14 | 0 | 9.55 | 22.23 | -2.1 - 21.19 | 0.3 - 85.75 | 2.62 | 1.3 - 5.59 | 0.2583 | 0.6781 | |
4ТM_TH22 | Abs_Value | 28 | 28 | 0 | 4.15 | 3.93 | 2.7 - 5.61 | 0.09 - 16.55 | 2.84 | 1.63 - 5.23 | 14 | 14 | 0 | 5.06 | 5.9 | 1.97 - 8.15 | 0.44 - 17.35 | 1.66 | 0.69 - 8.22 | 0.6107 | 0.7845 | |
4ТREG | Abs_Value | 28 | 28 | 0 | 2.75 | 3.7 | 1.38 - 4.12 | 0.02 - 16 | 1.38 | 0.9 - 2.78 | 14 | 14 | 0 | 4.35 | 5.5 | 1.47 - 7.23 | 0.12 - 14.85 | 1.4 | 0.74 - 7.52 | 0.3382 | 0.6781 | |
4ТREG(СТАР2) | Abs_Value | 28 | 28 | 0 | 90.87 | 75.13 | 63.04 - 118.69 | 6.1 - 296.08 | 68.88 | 41.46 - 106.71 | 14 | 14 | 0 | 130.77 | 113.81 | 71.16 - 190.39 | 33.78 - 462.62 | 81.71 | 57.83 - 189.89 | 0.2492 | 0.6781 | |
4ТREG_TH1 | Abs_Value | 28 | 28 | 0 | 0.26 | 0.26 | 0.16 - 0.35 | 0 - 1.28 | 0.2 | 0.08 - 0.3 | 14 | 14 | 0 | 0.34 | 0.47 | 0.09 - 0.58 | 0.06 - 1.9 | 0.21 | 0.1 - 0.32 | 0.5511 | 0.7482 | |
4ТREG_TH17 | Abs_Value | 28 | 28 | 0 | 3.91 | 3.31 | 2.69 - 5.14 | 0.31 - 12.56 | 2.76 | 1.86 - 4.74 | 14 | 14 | 0 | 6.68 | 8.57 | 2.19 - 11.16 | 1.2 - 33.26 | 3.34 | 1.93 - 7.31 | 0.2627 | 0.6781 | |
4ТREG_Th17TO1 | Abs_Value | 28 | 28 | 0 | 0.13 | 0.31 | 0.02 - 0.25 | 0 - 1.66 | 0.06 | 0.03 - 0.13 | 14 | 14 | 0 | 0.13 | 0.18 | 0.04 - 0.23 | 0.02 - 0.63 | 0.05 | 0.03 - 0.18 | 0.9919 | 0.9959 | |
4ТREG_TH2 | Abs_Value | 28 | 28 | 0 | 2.09 | 1.71 | 1.46 - 2.73 | 0.18 - 7.26 | 1.67 | 0.77 - 3.26 | 14 | 14 | 0 | 3.65 | 4.38 | 1.36 - 5.95 | 0.49 - 17.5 | 2.38 | 1.13 - 4.78 | 0.2189 | 0.6781 | |
4ТREG_TH22 | Abs_Value | 28 | 28 | 0 | 3.11 | 3.04 | 1.99 - 4.24 | 0.3 - 12.42 | 2.39 | 1.25 - 3.74 | 14 | 14 | 0 | 3.93 | 5.42 | 1.09 - 6.77 | 0.35 - 21.16 | 1.78 | 1.02 - 4.67 | 0.6063 | 0.7822 | |
4ТЕ | Abs_Value | 28 | 28 | 0 | 6.72 | 8.07 | 3.74 - 9.71 | 0.05 - 26.78 | 3.24 | 1.24 - 9.35 | 14 | 14 | 0 | 13.5 | 18.66 | 3.72 - 23.27 | 0.19 - 58.83 | 4.9 | 1.72 - 12.7 | 0.213 | 0.6781 | |
4ТЕ(СТАР2) | Abs_Value | 28 | 28 | 0 | 31.02 | 19.78 | 23.69 - 38.34 | 8.86 - 75.37 | 26.45 | 13.85 - 44.23 | 14 | 14 | 0 | 39.2 | 30.52 | 23.21 - 55.19 | 3.55 - 106.79 | 41.45 | 13.83 - 56.32 | 0.3736 | 0.6866 | |
4ТЕ_TH1 | Abs_Value | 28 | 28 | 0 | 2.42 | 3.41 | 1.15 - 3.68 | 0 - 13.95 | 0.63 | 0.27 - 3.19 | 14 | 14 | 0 | 3.48 | 5.58 | 0.55 - 6.4 | 0.01 - 16.37 | 1.35 | 0.21 - 2.73 | 0.5225 | 0.7387 | |
4ТЕ_TH17 | Abs_Value | 28 | 28 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.05 | 0 | 0 - 0.01 | 14 | 14 | 0 | 0.07 | 0.24 | -0.05 - 0.2 | 0 - 0.91 | 0 | 0 - 0.01 | 0.3494 | 0.6781 | |
4ТЕ_Th17TO1 | Abs_Value | 28 | 28 | 0 | 0.09 | 0.13 | 0.04 - 0.14 | 0 - 0.51 | 0.02 | 0 - 0.14 | 14 | 14 | 0 | 0.34 | 0.77 | -0.07 - 0.74 | 0 - 2.9 | 0.04 | 0 - 0.19 | 0.2571 | 0.6781 | |
4ТЕ_TH2 | Abs_Value | 28 | 28 | 0 | 0.46 | 0.69 | 0.2 - 0.71 | 0 - 2.26 | 0.06 | 0.01 - 0.58 | 14 | 14 | 0 | 0.59 | 1.53 | -0.21 - 1.39 | 0 - 5.84 | 0.14 | 0.03 - 0.29 | 0.7584 | 0.884 | |
4ТЕ_TH22 | Abs_Value | 28 | 28 | 0 | 0.01 | 0.02 | 0 - 0.02 | 0 - 0.09 | 0 | 0 - 0.01 | 14 | 14 | 0 | 0.01 | 0.01 | 0 - 0.02 | 0 - 0.05 | 0.01 | 0 - 0.02 | 0.7002 | 0.8548 | |
4ТЕ+226+ | Abs_Value | 28 | 28 | 0 | 28.62 | 18.94 | 21.61 - 35.64 | 5.39 - 69.68 | 23.92 | 13.41 - 41.25 | 14 | 14 | 0 | 35.9 | 28.65 | 20.89 - 50.9 | 3.23 - 101.25 | 34.74 | 13.45 - 52.71 | 0.4001 | 0.6866 | |
4ТЕ+39+ | Abs_Value | 28 | 28 | 0 | 6.91 | 6.93 | 4.34 - 9.47 | 0.19 - 30.14 | 5.03 | 1.49 - 9.56 | 14 | 14 | 0 | 7.6 | 7.97 | 3.42 - 11.77 | 0.03 - 29.54 | 6.06 | 1.39 - 11.47 | 0.7852 | 0.8997 | |
4ТЕ+DR+ | Abs_Value | 28 | 28 | 0 | 19.05 | 16.74 | 12.85 - 25.25 | 2.33 - 69.31 | 15.63 | 8.38 - 20.29 | 14 | 14 | 0 | 18.69 | 18.7 | 8.89 - 28.49 | 0.08 - 60.5 | 14.65 | 6.75 - 20.78 | 0.9522 | 0.9711 | |
4ТЕ+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 9.06 | 6.86 | 6.52 - 11.6 | 0.69 - 29.76 | 7.41 | 3.88 - 12.42 | 14 | 14 | 0 | 15.11 | 13.39 | 8.09 - 22.13 | 1.05 - 47.45 | 10.59 | 5.29 - 23.72 | 0.1309 | 0.6781 | |
4ТЕ+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 1.87 | 1.73 | 1.22 - 2.51 | 0.07 - 8.02 | 1.4 | 0.7 - 2.21 | 14 | 14 | 0 | 2.7 | 2.9 | 1.18 - 4.22 | 0.13 - 9.27 | 0.93 | 0.55 - 4.17 | 0.335 | 0.6781 | |
4ТЕ+PD-1+ | Abs_Value | 28 | 28 | 0 | 20.09 | 15.55 | 14.33 - 25.85 | 4.6 - 58.48 | 15.83 | 8.96 - 25.92 | 14 | 14 | 0 | 21.39 | 19.12 | 11.37 - 31.4 | 0.77 - 67.28 | 18.59 | 6.5 - 26.82 | 0.8281 | 0.9094 | |
4ТЕ+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 11.17 | 10.71 | 7.2 - 15.14 | 1.41 - 39.92 | 6.31 | 4.63 - 12.94 | 14 | 14 | 0 | 13.62 | 14.7 | 5.92 - 21.32 | 0.44 - 55.01 | 9.37 | 4.15 - 16.57 | 0.5853 | 0.7646 | |
4ТЕ+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 8.92 | 6.9 | 6.37 - 11.48 | 1.92 - 25.95 | 6.34 | 4.22 - 11.45 | 14 | 14 | 0 | 7.77 | 7.08 | 4.06 - 11.47 | 0.33 - 22.79 | 5.5 | 1.8 - 12.24 | 0.6192 | 0.7904 | |
4ТЕ+TIGIT+ | Abs_Value | 28 | 28 | 0 | 10.79 | 7.88 | 7.87 - 13.71 | 2.51 - 30.84 | 8.43 | 5.19 - 14.18 | 14 | 14 | 0 | 10.47 | 9.63 | 5.42 - 15.51 | 0.46 - 32.06 | 7.69 | 2.46 - 15.9 | 0.9148 | 0.956 | |
4ТМ | Abs_Value | 28 | 28 | 0 | 109.01 | 67.42 | 84.03 - 133.98 | 32.08 - 253.34 | 82.13 | 53.03 - 141.37 | 14 | 14 | 0 | 93.26 | 64.47 | 59.48 - 127.03 | 14.63 - 197.92 | 80.46 | 41.2 - 144.82 | 0.4687 | 0.718 | |
8+ | Abs_Value | 28 | 28 | 0 | 622.09 | 563.47 | 413.38 - 830.81 | 31.86 - 2078.56 | 508.16 | 107.88 - 982.15 | 14 | 14 | 0 | 371.07 | 337.5 | 194.28 - 547.86 | 2.77 - 942.86 | 259.72 | 57.26 - 608.29 | 0.0799 | 0.6781 | |
8+ (IM STAT) | Abs_Value | 28 | 28 | 0 | 806.12 | 725.48 | 537.4 - 1074.84 | 40.65 - 2479.37 | 632.98 | 234.59 - 1142.94 | 14 | 14 | 0 | 472.41 | 437.65 | 243.15 - 701.67 | 3.11 - 1413.27 | 383.59 | 88.25 - 709.03 | 0.0718 | 0.6781 | |
8+226+ | Abs_Value | 28 | 28 | 0 | 1002.67 | 905.76 | 667.17 - 1338.17 | 109.2 - 3905.17 | 724.17 | 336.58 - 1226.89 | 14 | 14 | 0 | 628.39 | 516.74 | 357.7 - 899.07 | 16.08 - 1833.29 | 558.95 | 189.54 - 973.48 | 0.0967 | 0.6781 | |
8+39+ | Abs_Value | 28 | 28 | 0 | 179.05 | 399.93 | 30.91 - 327.19 | 2.21 - 2089.83 | 65.06 | 28.88 - 134.15 | 14 | 14 | 0 | 108.54 | 95.6 | 58.46 - 158.62 | 0.53 - 266.18 | 81.42 | 23.84 - 181.37 | 0.3833 | 0.6866 | |
8+DR+ | Abs_Value | 28 | 28 | 0 | 821.88 | 776.49 | 534.26 - 1109.5 | 36.66 - 3420.38 | 664.31 | 204.99 - 1135.08 | 14 | 14 | 0 | 465.82 | 437.17 | 236.81 - 694.82 | 3.7 - 1528.67 | 351.66 | 136.04 - 604.53 | 0.065 | 0.6781 | |
8+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 325.57 | 336.9 | 200.78 - 450.36 | 22.38 - 1345.43 | 230.47 | 60.24 - 415.57 | 14 | 14 | 0 | 229.44 | 191.28 | 129.24 - 329.64 | 10.99 - 612.35 | 201.15 | 90.92 - 361.15 | 0.2462 | 0.6781 | |
8+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 361.91 | 450.75 | 194.95 - 528.87 | 9.64 - 1906.78 | 198.53 | 112.67 - 338.93 | 14 | 14 | 0 | 163.73 | 156.05 | 81.98 - 245.47 | 0.61 - 587.72 | 112.8 | 63.09 - 234.43 | 0.0436 | 0.6781 | |
8+PD-1+ | Abs_Value | 28 | 28 | 0 | 411.44 | 357.34 | 279.08 - 543.8 | 50.77 - 1157.32 | 242.05 | 152.08 - 581.29 | 14 | 14 | 0 | 297.17 | 333.76 | 122.34 - 472.01 | 5.1 - 1050.36 | 159.01 | 59.23 - 468.65 | 0.3159 | 0.6781 | |
8+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 92.8 | 86.8 | 60.64 - 124.95 | 3.08 - 350.2 | 71.08 | 33.32 - 120.94 | 14 | 14 | 0 | 101.97 | 140.21 | 28.52 - 175.41 | 3.19 - 429.98 | 40.54 | 9.22 - 155.68 | 0.8251 | 0.9094 | |
8+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 318.65 | 299.61 | 207.67 - 429.62 | 46.78 - 1020.62 | 184.97 | 102.83 - 432.2 | 14 | 14 | 0 | 195.21 | 199.07 | 90.93 - 299.49 | 1.91 - 620.38 | 112.82 | 50.02 - 325.98 | 0.1207 | 0.6781 | |
8+TIGIT+ | Abs_Value | 28 | 28 | 0 | 680.56 | 684.87 | 426.88 - 934.23 | 83.69 - 2694.32 | 445.34 | 208.98 - 860.66 | 14 | 14 | 0 | 358.94 | 319.1 | 191.78 - 526.09 | 2.52 - 917.19 | 249.08 | 109.73 - 599.54 | 0.0445 | 0.6781 | |
8EMTM | Abs_Value | 28 | 28 | 0 | 297.12 | 413.32 | 144.02 - 450.21 | 7.83 - 1882.93 | 118.32 | 33.55 - 468.12 | 14 | 14 | 0 | 108.26 | 114.49 | 48.29 - 168.24 | 1.35 - 336.64 | 47.26 | 26.7 - 176.25 | 0.0309 | 0.6781 | |
8EMTM+226+ | Abs_Value | 28 | 28 | 0 | 262.72 | 393.38 | 117.01 - 408.43 | 7.18 - 1881.01 | 107.78 | 30.67 - 330.96 | 14 | 14 | 0 | 90.82 | 94.44 | 41.36 - 140.29 | 1.28 - 270.09 | 37.28 | 21.54 - 160.05 | 0.0358 | 0.6781 | |
8EMTM+39+ | Abs_Value | 28 | 28 | 0 | 75.18 | 204.28 | -0.48 - 150.85 | 0.15 - 979.7 | 13.33 | 3.81 - 46.74 | 14 | 14 | 0 | 32.61 | 38.02 | 12.69 - 52.52 | 0.1 - 115.58 | 11.44 | 5.54 - 57.22 | 0.2946 | 0.6781 | |
8EMTM+DR+ | Abs_Value | 28 | 28 | 0 | 253.32 | 362.91 | 118.89 - 387.74 | 3.36 - 1678.23 | 111.52 | 23.45 - 398.7 | 14 | 14 | 0 | 89.85 | 96.75 | 39.17 - 140.53 | 0.6 - 266.01 | 40.98 | 18.71 - 127.09 | 0.0325 | 0.6781 | |
8EMTM+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 78.51 | 128.66 | 30.85 - 126.16 | 0.77 - 396.55 | 20.79 | 3.43 - 68.29 | 14 | 14 | 0 | 20.46 | 23.19 | 8.31 - 32.61 | 0.57 - 81.18 | 14.3 | 5.74 - 21.89 | 0.0277 | 0.6781 | |
8EMTM+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 80.36 | 173.57 | 16.07 - 144.65 | 0.65 - 878.14 | 26.76 | 4.11 - 51.64 | 14 | 14 | 0 | 19.34 | 28.41 | 4.46 - 34.22 | 0.06 - 105.56 | 7.53 | 4.44 - 20.2 | 0.08 | 0.6781 | |
8EMTM+PD-1+ | Abs_Value | 28 | 28 | 0 | 138.25 | 190.06 | 67.85 - 208.65 | 2.76 - 628.57 | 55.93 | 23.94 - 121.89 | 14 | 14 | 0 | 68.46 | 80.08 | 26.51 - 110.41 | 0.72 - 222.51 | 27.74 | 13.79 - 80.99 | 0.103 | 0.6781 | |
8EMTM+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 29.59 | 41.13 | 14.36 - 44.83 | 0.58 - 176.22 | 11.82 | 4 - 44.68 | 14 | 14 | 0 | 20.55 | 29.3 | 5.2 - 35.9 | 0.5 - 91.63 | 6.05 | 2.11 - 25.21 | 0.4182 | 0.6976 | |
8EMTM+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 108.66 | 159.34 | 49.64 - 167.68 | 2.05 - 544.23 | 35.07 | 19.33 - 100.5 | 14 | 14 | 0 | 47.91 | 56.83 | 18.14 - 77.68 | 0.22 - 167.49 | 21.69 | 11.54 - 52.86 | 0.0797 | 0.6781 | |
8EMTM+TIGIT+ | Abs_Value | 28 | 28 | 0 | 189.02 | 302.12 | 77.12 - 300.93 | 4.08 - 1330.49 | 66.41 | 23.7 - 205.97 | 14 | 14 | 0 | 67.25 | 82.58 | 23.99 - 110.51 | 0.28 - 273.06 | 29.94 | 16.68 - 82.47 | 0.0547 | 0.6781 | |
8NV | Abs_Value | 28 | 28 | 0 | 21.59 | 23.9 | 12.74 - 30.45 | 1.08 - 117.97 | 16.42 | 9.44 - 22.67 | 14 | 14 | 0 | 24.99 | 15.76 | 16.73 - 33.24 | 2.58 - 62.15 | 23.87 | 17.89 - 30.86 | 0.5859 | 0.7646 | |
8NV(СТАР2) | Abs_Value | 28 | 28 | 0 | 25.71 | 29.33 | 14.85 - 36.58 | 1.52 - 104.32 | 16.23 | 9.59 - 25.92 | 14 | 14 | 0 | 23.68 | 15.83 | 15.39 - 31.98 | 2.85 - 55.29 | 23.65 | 12.38 - 28.58 | 0.7728 | 0.8946 | |
8NV+226+ | Abs_Value | 28 | 28 | 0 | 22.4 | 26.13 | 12.72 - 32.08 | 1.4 - 96.72 | 14.48 | 9.13 - 23.05 | 14 | 14 | 0 | 21.49 | 15.19 | 13.53 - 29.45 | 2.73 - 54.93 | 21.56 | 10.55 - 25.09 | 0.8881 | 0.9417 | |
8NV+39+ | Abs_Value | 28 | 28 | 0 | 1.56 | 2.33 | 0.7 - 2.42 | 0.02 - 11.42 | 0.78 | 0.25 - 1.66 | 14 | 14 | 0 | 2.11 | 2.34 | 0.89 - 3.34 | 0.07 - 8.56 | 1.34 | 0.31 - 3.21 | 0.4782 | 0.7185 | |
8NV+DR+ | Abs_Value | 28 | 28 | 0 | 6.17 | 10.12 | 2.42 - 9.91 | 0.12 - 49.7 | 2.7 | 1.26 - 4.71 | 14 | 14 | 0 | 3.34 | 2.64 | 1.96 - 4.72 | 0.26 - 7.84 | 2.29 | 1.05 - 5.31 | 0.1755 | 0.6781 | |
8NV+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 17.04 | 23.81 | 8.22 - 25.86 | 0.93 - 101.41 | 10.66 | 4.93 - 15.8 | 14 | 14 | 0 | 18.89 | 13.6 | 11.76 - 26.01 | 1.46 - 46.07 | 18.38 | 8.18 - 23.33 | 0.7507 | 0.884 | |
8NV+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 2.24 | 2.68 | 1.25 - 3.23 | 0.03 - 11.3 | 1.55 | 0.34 - 3.23 | 14 | 14 | 0 | 1.51 | 1.78 | 0.58 - 2.44 | 0.04 - 6.46 | 0.76 | 0.46 - 1.73 | 0.3 | 0.6781 | |
8NV+PD-1+ | Abs_Value | 28 | 28 | 0 | 6.43 | 15.22 | 0.79 - 12.07 | 0.07 - 81.13 | 1.76 | 0.97 - 6.11 | 14 | 14 | 0 | 3.28 | 2.88 | 1.78 - 4.79 | 0.21 - 8.57 | 2.47 | 0.8 - 5.02 | 0.2988 | 0.6781 | |
8NV+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 2.57 | 6.54 | 0.15 - 5 | 0 - 33.28 | 0.59 | 0.23 - 1.48 | 14 | 14 | 0 | 1.62 | 2.37 | 0.38 - 2.86 | 0.03 - 8.09 | 0.6 | 0.17 - 1.4 | 0.4967 | 0.7192 | |
8NV+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 3.86 | 9.06 | 0.5 - 7.21 | 0.07 - 47.85 | 1.05 | 0.52 - 3.46 | 14 | 14 | 0 | 1.66 | 1.33 | 0.97 - 2.36 | 0.12 - 3.69 | 1.47 | 0.5 - 2.93 | 0.2197 | 0.6781 | |
8NV+TIGIT+ | Abs_Value | 28 | 28 | 0 | 6.1 | 10.28 | 2.29 - 9.91 | 0.3 - 51.41 | 2.39 | 1.28 - 5.55 | 14 | 14 | 0 | 3.17 | 2.45 | 1.89 - 4.46 | 0.16 - 9.39 | 2.43 | 1.43 - 4.38 | 0.1633 | 0.6781 | |
8TREG | Abs_Value | 28 | 28 | 0 | 679.26 | 594.1 | 459.2 - 899.32 | 31.9 - 1960.13 | 525.99 | 129.72 - 1051.71 | 14 | 14 | 0 | 382.04 | 350.32 | 198.53 - 565.55 | 2.7 - 946.35 | 277.39 | 59.9 - 604.13 | 0.0489 | 0.6781 | |
8ЕМ | Abs_Value | 28 | 28 | 0 | 291.16 | 561.39 | 83.22 - 499.11 | 1.35 - 2912.66 | 125.79 | 31.89 - 295.25 | 14 | 14 | 0 | 90.19 | 129.54 | 22.33 - 158.05 | 0.67 - 462.87 | 36.63 | 12.78 - 100.3 | 0.0811 | 0.6781 | |
8СМ | Abs_Value | 28 | 28 | 0 | 11.52 | 12.63 | 6.84 - 16.2 | 0.38 - 54.12 | 7.33 | 2.43 - 14.43 | 14 | 14 | 0 | 9.54 | 9.95 | 4.33 - 14.75 | 0.18 - 31.81 | 6.55 | 1.76 - 14.02 | 0.5836 | 0.7646 | |
8СМ(СТАР2) | Abs_Value | 28 | 28 | 0 | 12.03 | 22.84 | 3.57 - 20.49 | 0.51 - 115.04 | 4.3 | 1.89 - 8.54 | 14 | 14 | 0 | 6.81 | 9.89 | 1.63 - 11.99 | 0.11 - 35.91 | 2.44 | 0.66 - 6.83 | 0.3087 | 0.6781 | |
8СМ+226+ | Abs_Value | 28 | 28 | 0 | 10.52 | 21.31 | 2.63 - 18.42 | 0.44 - 108.09 | 3.47 | 1.75 - 5.99 | 14 | 14 | 0 | 5.24 | 7.02 | 1.56 - 8.91 | 0.11 - 25.41 | 2.05 | 0.61 - 5.89 | 0.2419 | 0.6781 | |
8СМ+39+ | Abs_Value | 28 | 28 | 0 | 2.85 | 4.64 | 1.13 - 4.57 | 0.01 - 20.23 | 1.11 | 0.43 - 3.12 | 14 | 14 | 0 | 3.3 | 5.33 | 0.51 - 6.1 | 0.01 - 18.76 | 0.64 | 0.22 - 4.13 | 0.7908 | 0.9 | |
8СМ+DR+ | Abs_Value | 28 | 28 | 0 | 9.66 | 17.15 | 3.31 - 16.02 | 0.24 - 80.54 | 2.92 | 1.56 - 6.47 | 14 | 14 | 0 | 5.39 | 9.41 | 0.46 - 10.32 | 0.03 - 34.59 | 1.62 | 0.36 - 4.96 | 0.3035 | 0.6781 | |
8СМ+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 3 | 6.6 | 0.55 - 5.44 | 0.05 - 32.39 | 0.87 | 0.29 - 1.87 | 14 | 14 | 0 | 1.37 | 2.12 | 0.26 - 2.48 | 0.07 - 8.16 | 0.49 | 0.27 - 1.5 | 0.2416 | 0.6781 | |
8СМ+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 1.91 | 3.44 | 0.64 - 3.18 | 0.04 - 14.86 | 0.7 | 0.37 - 1.31 | 14 | 14 | 0 | 1.23 | 1.53 | 0.43 - 2.04 | 0 - 4.15 | 0.36 | 0.1 - 2.61 | 0.3841 | 0.6866 | |
8СМ+PD-1+ | Abs_Value | 28 | 28 | 0 | 7.12 | 14.26 | 1.84 - 12.4 | 0.05 - 71.03 | 2.34 | 0.96 - 4.64 | 14 | 14 | 0 | 4.21 | 8.1 | -0.03 - 8.46 | 0.05 - 30.23 | 1.56 | 0.36 - 2.97 | 0.4047 | 0.6902 | |
8СМ+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 1.78 | 6.19 | -0.52 - 4.07 | 0 - 33.01 | 0.26 | 0.16 - 0.61 | 14 | 14 | 0 | 0.61 | 1.47 | -0.16 - 1.38 | 0 - 5.66 | 0.15 | 0.08 - 0.32 | 0.3502 | 0.6781 | |
8СМ+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 5.34 | 8.9 | 2.05 - 8.64 | 0.05 - 38.02 | 2.19 | 0.73 - 4.38 | 14 | 14 | 0 | 3.6 | 6.72 | 0.08 - 7.12 | 0.01 - 24.57 | 1.36 | 0.23 - 2.52 | 0.4838 | 0.7191 | |
8СМ+TIGIT+ | Abs_Value | 28 | 28 | 0 | 7.25 | 11.51 | 2.99 - 11.52 | 0.4 - 49.64 | 2.65 | 1.25 - 5.84 | 14 | 14 | 0 | 4.84 | 7.96 | 0.67 - 9.01 | 0.01 - 28.72 | 1.75 | 0.32 - 5.24 | 0.4319 | 0.7016 | |
8ТЕ | Abs_Value | 28 | 28 | 0 | 559.44 | 510.22 | 370.45 - 748.43 | 21.49 - 1984.18 | 386.13 | 153.78 - 765.25 | 14 | 14 | 0 | 420.95 | 394.25 | 214.43 - 627.47 | 7.02 - 1388.56 | 342.96 | 112.41 - 593 | 0.3393 | 0.6781 | |
8ТЕ(СТАР2) | Abs_Value | 28 | 28 | 0 | 760.76 | 651.04 | 519.61 - 1001.91 | 85.43 - 2454.12 | 597.34 | 233.36 - 973.93 | 14 | 14 | 0 | 549.84 | 485.59 | 295.48 - 804.21 | 7.28 - 1753.87 | 466.62 | 147.37 - 857.41 | 0.2465 | 0.6781 | |
8ТЕ+226+ | Abs_Value | 28 | 28 | 0 | 704.58 | 620.82 | 474.63 - 934.54 | 70.48 - 2224.98 | 536.59 | 198.58 - 886.97 | 14 | 14 | 0 | 509.43 | 457.91 | 269.56 - 749.3 | 7.03 - 1680.66 | 433.53 | 143.45 - 734.61 | 0.2577 | 0.6781 | |
8ТЕ+39+ | Abs_Value | 28 | 28 | 0 | 99.09 | 204.61 | 23.3 - 174.88 | 1.13 - 1085.66 | 36.16 | 19.58 - 97.46 | 14 | 14 | 0 | 69.82 | 56.96 | 39.98 - 99.66 | 0.35 - 156.59 | 66.19 | 19.81 - 122.1 | 0.4859 | 0.7192 | |
8ТЕ+DR+ | Abs_Value | 28 | 28 | 0 | 550.8 | 518.65 | 358.69 - 742.91 | 32.15 - 1885.95 | 371.81 | 169.71 - 755.01 | 14 | 14 | 0 | 366.48 | 382.45 | 166.14 - 566.82 | 2.71 - 1408.92 | 283.06 | 108.34 - 403.66 | 0.2018 | 0.6781 | |
8ТЕ+PD-1-TIGIT- | Abs_Value | 28 | 28 | 0 | 226.53 | 232.94 | 140.25 - 312.82 | 8.85 - 977.38 | 164.89 | 42.74 - 353.97 | 14 | 14 | 0 | 188.06 | 174.91 | 96.44 - 279.69 | 3.37 - 546.54 | 169.72 | 26.6 - 300.93 | 0.5531 | 0.7482 | |
8ТЕ+PD-1-TIGIT+ | Abs_Value | 28 | 28 | 0 | 277.01 | 322.66 | 157.5 - 396.53 | 7.28 - 1118.76 | 123.53 | 75.39 - 287.87 | 14 | 14 | 0 | 141.13 | 133.62 | 71.14 - 211.13 | 0.49 - 476.45 | 94.63 | 53.31 - 192.7 | 0.0618 | 0.6781 | |
8ТЕ+PD-1+ | Abs_Value | 28 | 28 | 0 | 257.22 | 242.24 | 167.49 - 346.94 | 17.31 - 1012.86 | 154.35 | 86.77 - 439.93 | 14 | 14 | 0 | 220.64 | 278.8 | 74.6 - 366.68 | 3.41 - 959.6 | 108.29 | 34.51 - 279.19 | 0.6797 | 0.8445 | |
8ТЕ+PD-1+TIGIT- | Abs_Value | 28 | 28 | 0 | 58.57 | 57.31 | 37.35 - 79.8 | 1.78 - 217.83 | 39.31 | 22.3 - 67.46 | 14 | 14 | 0 | 79.23 | 118.31 | 17.25 - 141.2 | 1.91 - 388.34 | 30.42 | 5.88 - 75.42 | 0.5453 | 0.7482 | |
8ТЕ+PD-1+TIGIT+ | Abs_Value | 28 | 28 | 0 | 198.64 | 200.93 | 124.21 - 273.07 | 15.53 - 830.14 | 115.53 | 61.29 - 258.57 | 14 | 14 | 0 | 141.41 | 163.22 | 55.91 - 226.92 | 1.5 - 571.26 | 74.7 | 27.15 - 208.77 | 0.33 | 0.6781 | |
8ТЕ+TIGIT+ | Abs_Value | 28 | 28 | 0 | 475.65 | 478.92 | 298.26 - 653.05 | 60.35 - 1948.91 | 252.29 | 153.4 - 603.44 | 14 | 14 | 0 | 282.55 | 260.54 | 146.07 - 419.03 | 1.99 - 818.99 | 211.43 | 85.61 - 488.13 | 0.0987 | 0.6781 | |
8ТМ | Abs_Value | 28 | 28 | 0 | 103.51 | 167.34 | 41.52 - 165.49 | 2.77 - 712.4 | 34.28 | 16.32 - 98.29 | 14 | 14 | 0 | 49.25 | 78.03 | 8.38 - 90.13 | 0.73 - 307.9 | 27.39 | 15.88 - 50.35 | 0.1599 | 0.6781 | |
TREG_CM | Abs_Value | 28 | 28 | 0 | 2.14 | 2.4 | 1.25 - 3.03 | 0.05 - 9.79 | 1.38 | 0.49 - 2.36 | 14 | 14 | 0 | 2.57 | 3.89 | 0.53 - 4.61 | 0.08 - 14.95 | 1.28 | 0.6 - 1.82 | 0.7069 | 0.8566 | |
TREG_EMTM | Abs_Value | 28 | 28 | 0 | 17.07 | 15.93 | 11.16 - 22.97 | 1.71 - 79.04 | 11.8 | 7.19 - 20.87 | 14 | 14 | 0 | 23.74 | 23.55 | 11.4 - 36.07 | 3.25 - 71.51 | 13.29 | 6.66 - 30.27 | 0.3508 | 0.6781 | |
TREG_NV | Abs_Value | 28 | 28 | 0 | 2.24 | 2.91 | 1.16 - 3.32 | 0.02 - 11.22 | 1.29 | 0.44 - 2.39 | 14 | 14 | 0 | 2.21 | 2.61 | 0.85 - 3.58 | 0.49 - 10.39 | 1.26 | 0.64 - 2.63 | 0.9759 | 0.9879 | |
TREG_TE | Abs_Value | 28 | 28 | 0 | 4.46 | 4.48 | 2.8 - 6.12 | 0.29 - 19.01 | 3.7 | 2.1 - 5.47 | 14 | 14 | 0 | 4.99 | 5.47 | 2.13 - 7.85 | 0.54 - 18.3 | 3.13 | 1.41 - 6.1 | 0.7545 | 0.884 | |
TREG+226-TIGIT- | Abs_Value | 28 | 28 | 0 | 1.91 | 2.28 | 1.07 - 2.76 | 0.06 - 11.41 | 1.39 | 0.6 - 2.11 | 14 | 14 | 0 | 1.4 | 1.22 | 0.76 - 2.05 | 0.31 - 4.01 | 1.07 | 0.42 - 1.65 | 0.3556 | 0.6781 | |
TREG+226-TIGIT+ | Abs_Value | 28 | 28 | 0 | 6.74 | 8.02 | 3.76 - 9.71 | 0.18 - 38.6 | 5.2 | 2.3 - 7.67 | 14 | 14 | 0 | 7.97 | 7.25 | 4.17 - 11.76 | 1.07 - 20.55 | 4.6 | 2.36 - 11.54 | 0.6201 | 0.7904 | |
TREG+226+ | Abs_Value | 28 | 28 | 0 | 17.57 | 14.26 | 12.28 - 22.85 | 2.11 - 72.09 | 13.14 | 8.74 - 23.1 | 14 | 14 | 0 | 24.28 | 23.94 | 11.73 - 36.82 | 3.56 - 75.66 | 15.56 | 8.02 - 25.79 | 0.3469 | 0.6781 | |
TREG+226+TIGIT- | Abs_Value | 28 | 28 | 0 | 2.66 | 2.05 | 1.9 - 3.43 | 0.72 - 9.99 | 2.19 | 1.3 - 3.23 | 14 | 14 | 0 | 2.42 | 1.96 | 1.39 - 3.45 | 0.39 - 6.34 | 1.77 | 0.79 - 3.59 | 0.7059 | 0.8566 | |
TREG+226+TIGIT+ | Abs_Value | 28 | 28 | 0 | 14.9 | 12.92 | 10.12 - 19.69 | 1.18 - 66.55 | 11.55 | 7.27 - 20.12 | 14 | 14 | 0 | 21.86 | 22.38 | 10.14 - 33.58 | 3.17 - 69.85 | 14.16 | 5.8 - 24.61 | 0.296 | 0.6781 | |
TREG+39+ | Abs_Value | 28 | 28 | 0 | 19.34 | 18.14 | 12.62 - 26.06 | 1.99 - 77.53 | 14.73 | 6.89 - 25.57 | 14 | 14 | 0 | 23.53 | 22.77 | 11.6 - 35.46 | 1.37 - 84.95 | 16.15 | 8.12 - 28.06 | 0.5548 | 0.7482 | |
TREG+DR+ | Abs_Value | 28 | 28 | 0 | 18.53 | 15.12 | 12.93 - 24.13 | 1.78 - 70.63 | 14.35 | 9.08 - 24.63 | 14 | 14 | 0 | 24.48 | 24.67 | 11.56 - 37.41 | 2.12 - 76.07 | 14.29 | 6.38 - 26.68 | 0.4181 | 0.6976 | |
TREG+PD-1+ | Abs_Value | 28 | 28 | 0 | 10.89 | 9.84 | 7.24 - 14.53 | 0.6 - 38.32 | 7.38 | 4.29 - 14.03 | 14 | 14 | 0 | 14.55 | 15.86 | 6.24 - 22.86 | 1.03 - 49.25 | 7.67 | 3.58 - 21.24 | 0.4391 | 0.7016 | |
TREG+TIGIT+ | Abs_Value | 28 | 28 | 0 | 21.64 | 17.99 | 14.97 - 28.3 | 1.42 - 73.15 | 18.37 | 9.26 - 25.7 | 14 | 14 | 0 | 29.83 | 29.43 | 14.41 - 45.25 | 4.64 - 90.4 | 17.4 | 7.87 - 35.58 | 0.3518 | 0.6781 | |
+365 | 4_TFH | Abs_Value | 13 | 13 | 0 | 65.34 | 37.16 | 45.14 - 85.54 | 5.63 - 132.09 | 55.23 | 38.65 - 82.38 | 13 | 13 | 0 | 47.29 | 18.76 | 37.09 - 57.49 | 9.47 - 72.66 | 48.7 | 31.58 - 58.4 | 0.1356 | 0.6781 |
4_TH1 | Abs_Value | 13 | 13 | 0 | 64.63 | 39.03 | 43.42 - 85.85 | 9.91 - 143.83 | 54.59 | 38.59 - 83.06 | 13 | 13 | 0 | 51.88 | 51.35 | 23.97 - 79.8 | 4.31 - 161.95 | 30.9 | 24.11 - 47.41 | 0.4833 | 0.7191 | |
4_TH17 | Abs_Value | 13 | 13 | 0 | 22.1 | 10.62 | 16.32 - 27.87 | 7.99 - 40.27 | 20.97 | 11.82 - 31.4 | 13 | 13 | 0 | 34.53 | 29.41 | 18.54 - 50.52 | 8.97 - 109.23 | 27.65 | 10.99 - 43.52 | 0.1721 | 0.6781 | |
4_Th17TO1 | Abs_Value | 13 | 13 | 0 | 13.04 | 11.55 | 6.76 - 19.32 | 2.42 - 39.63 | 7.87 | 5.63 - 16.31 | 13 | 13 | 0 | 12.94 | 11.49 | 6.69 - 19.19 | 0.78 - 39.95 | 11.04 | 5.89 - 12.47 | 0.9829 | 0.9889 | |
4_TH2 | Abs_Value | 13 | 13 | 0 | 16.53 | 8.19 | 12.08 - 20.98 | 6.89 - 32.23 | 12.56 | 10.25 - 22.2 | 13 | 13 | 0 | 30.97 | 23.54 | 18.18 - 43.77 | 2.45 - 80.42 | 22.23 | 14.68 - 46.11 | 0.0543 | 0.6781 | |
4_TH22 | Abs_Value | 13 | 13 | 0 | 9.21 | 7.41 | 5.18 - 13.24 | 0.85 - 24.41 | 7.54 | 3.3 - 10.42 | 13 | 13 | 0 | 12.98 | 13.47 | 5.66 - 20.3 | 2.27 - 43.52 | 6.25 | 4.4 - 15.95 | 0.3877 | 0.6866 | |
4+ | Abs_Value | 13 | 13 | 0 | 159.05 | 136.59 | 84.8 - 233.3 | 52.48 - 526.69 | 107.32 | 91.29 - 157.54 | 13 | 13 | 0 | 172.82 | 136.8 | 98.46 - 247.19 | 20.84 - 561.4 | 130.33 | 87.45 - 197.84 | 0.7994 | 0.9 | |
4+ (IM STAT) | Abs_Value | 13 | 13 | 0 | 137.87 | 118.1 | 73.67 - 202.07 | 31.83 - 437.37 | 99.83 | 69.48 - 153.93 | 13 | 13 | 0 | 148.86 | 129.99 | 78.19 - 219.52 | 34.32 - 535.83 | 107.92 | 75.74 - 188.69 | 0.8235 | 0.9094 | |
4+226+ | Abs_Value | 13 | 13 | 0 | 434.09 | 215.97 | 316.69 - 551.5 | 148.12 - 908.92 | 418.16 | 322.85 - 569.2 | 13 | 13 | 0 | 367.91 | 194.37 | 262.25 - 473.57 | 151.09 - 689.45 | 315.14 | 175.04 - 503.96 | 0.4197 | 0.6976 | |
4+39+ | Abs_Value | 13 | 13 | 0 | 72.82 | 50.19 | 45.54 - 100.1 | 1.86 - 157.32 | 60.9 | 38.64 - 114.42 | 13 | 13 | 0 | 74.42 | 74.23 | 34.07 - 114.77 | 3 - 294.7 | 60.08 | 35.85 - 82.73 | 0.9493 | 0.9711 | |
4+DR+ | Abs_Value | 13 | 13 | 0 | 203.14 | 165.82 | 113 - 293.28 | 35.88 - 695.8 | 161.93 | 120.52 - 239.44 | 13 | 13 | 0 | 133.82 | 113.21 | 72.28 - 195.36 | 37.87 - 433.17 | 95.63 | 55.05 - 152.03 | 0.2268 | 0.6781 | |
4+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 165.45 | 107.03 | 107.26 - 223.63 | 21.66 - 409.4 | 156.17 | 91.71 - 213.7 | 13 | 13 | 0 | 185.55 | 122.99 | 118.69 - 252.41 | 24.56 - 339.45 | 150.3 | 79.8 - 326.94 | 0.6607 | 0.8271 | |
4+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 16.44 | 17.32 | 7.02 - 25.86 | 2.68 - 63.64 | 9.45 | 6.4 - 17.7 | 13 | 13 | 0 | 17.39 | 13.74 | 9.92 - 24.87 | 2.16 - 46.7 | 16.77 | 5.77 - 21.51 | 0.8777 | 0.9388 | |
4+PD-1+ | Abs_Value | 13 | 13 | 0 | 272.3 | 172.15 | 178.72 - 365.88 | 68.05 - 718.28 | 212.65 | 175.68 - 364.54 | 13 | 13 | 0 | 196.05 | 112.02 | 135.15 - 256.95 | 83.25 - 411.97 | 154.89 | 113.41 - 227.46 | 0.1953 | 0.6781 | |
4+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 146.17 | 77.12 | 104.24 - 188.09 | 32.8 - 282.13 | 132.55 | 92.16 - 201.04 | 13 | 13 | 0 | 107.58 | 67.37 | 70.96 - 144.21 | 46.73 - 237.8 | 79.56 | 56.16 - 133.4 | 0.1872 | 0.6781 | |
4+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 126.13 | 107.17 | 67.88 - 184.39 | 35.25 - 436.15 | 83.52 | 68.11 - 152.21 | 13 | 13 | 0 | 88.47 | 54.2 | 59 - 117.93 | 30.53 - 233.4 | 75.33 | 55.61 - 113.02 | 0.2732 | 0.6781 | |
4+TIGIT+ | Abs_Value | 13 | 13 | 0 | 142.57 | 121.53 | 76.51 - 208.64 | 43.18 - 499.79 | 99.63 | 74.52 - 168.55 | 13 | 13 | 0 | 105.86 | 60.23 | 73.12 - 138.6 | 32.86 - 256.89 | 101.96 | 75.38 - 140.76 | 0.3424 | 0.6781 | |
4NV | Abs_Value | 13 | 13 | 0 | 83.4 | 55.4 | 53.28 - 113.51 | 2.54 - 194.07 | 71.69 | 45.79 - 109.06 | 13 | 13 | 0 | 94.65 | 79.18 | 51.61 - 137.69 | 7.74 - 219.7 | 69.52 | 34.57 - 167.25 | 0.6788 | 0.8445 | |
4NV(СТАР2) | Abs_Value | 13 | 13 | 0 | 71.79 | 48.37 | 45.5 - 98.08 | 1.85 - 171.15 | 63.56 | 33.81 - 105.47 | 13 | 13 | 0 | 89.8 | 80.11 | 46.25 - 133.35 | 7.32 - 237.87 | 56.13 | 28.32 - 149.96 | 0.4959 | 0.7192 | |
4NV_TH1 | Abs_Value | 13 | 13 | 0 | 4.35 | 3.03 | 2.7 - 6 | 0.17 - 12.15 | 4.03 | 2.45 - 5.59 | 13 | 13 | 0 | 7.88 | 9.31 | 2.82 - 12.95 | 0.56 - 30 | 3.45 | 0.75 - 7.62 | 0.2135 | 0.6781 | |
4NV_TH17 | Abs_Value | 13 | 13 | 0 | 2.16 | 1.44 | 1.38 - 2.95 | 0.4 - 5.09 | 2.02 | 1.3 - 2.34 | 13 | 13 | 0 | 2.65 | 2.59 | 1.24 - 4.06 | 0.16 - 8.85 | 1.59 | 1.21 - 2.92 | 0.5581 | 0.7482 | |
4NV_Th17TO1 | Abs_Value | 13 | 13 | 0 | 0.47 | 0.36 | 0.27 - 0.66 | 0.01 - 1.3 | 0.48 | 0.14 - 0.58 | 13 | 13 | 0 | 0.71 | 0.62 | 0.37 - 1.05 | 0.05 - 2.08 | 0.44 | 0.35 - 1.02 | 0.2427 | 0.6781 | |
4NV_TH2 | Abs_Value | 13 | 13 | 0 | 5.6 | 4.78 | 3 - 8.2 | 0.5 - 15.38 | 3.94 | 2.56 - 7.64 | 13 | 13 | 0 | 6.66 | 4.7 | 4.1 - 9.22 | 0.21 - 13.51 | 6.09 | 2.92 - 10.3 | 0.573 | 0.7599 | |
4NV_TH22 | Abs_Value | 13 | 13 | 0 | 0.19 | 0.18 | 0.09 - 0.29 | 0.02 - 0.61 | 0.1 | 0.07 - 0.35 | 13 | 13 | 0 | 0.21 | 0.21 | 0.1 - 0.33 | 0 - 0.63 | 0.12 | 0.06 - 0.3 | 0.7948 | 0.9 | |
4NV+226+ | Abs_Value | 13 | 13 | 0 | 63.84 | 42.61 | 40.67 - 87 | 1.8 - 148.33 | 61.02 | 31.32 - 92.36 | 13 | 13 | 0 | 77.25 | 69.95 | 39.23 - 115.28 | 6.18 - 203.08 | 46.99 | 23.72 - 137.98 | 0.5615 | 0.7507 | |
4NV+39+ | Abs_Value | 13 | 13 | 0 | 0.99 | 0.73 | 0.6 - 1.39 | 0.01 - 2.47 | 0.98 | 0.33 - 1.51 | 13 | 13 | 0 | 2.6 | 2.83 | 1.06 - 4.13 | 0.09 - 9.72 | 1.74 | 0.51 - 2.99 | 0.0686 | 0.6781 | |
4NV+DR+ | Abs_Value | 13 | 13 | 0 | 4.45 | 4.54 | 1.98 - 6.91 | 0.32 - 17.75 | 2.89 | 1.89 - 6 | 13 | 13 | 0 | 6.1 | 4.37 | 3.72 - 8.47 | 0.24 - 15.82 | 4.32 | 4.05 - 7.56 | 0.3547 | 0.6781 | |
4NV+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 64.15 | 44.02 | 40.22 - 88.08 | 1.55 - 158.4 | 59.59 | 23.79 - 90.38 | 13 | 13 | 0 | 82.01 | 75.65 | 40.89 - 123.14 | 3.6 - 218.79 | 46.91 | 24.7 - 143.53 | 0.4708 | 0.718 | |
4NV+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 1.17 | 0.8 | 0.73 - 1.6 | 0.12 - 2.96 | 1.03 | 0.73 - 1.25 | 13 | 13 | 0 | 2.87 | 4.3 | 0.53 - 5.21 | 0.12 - 15.6 | 1.05 | 0.52 - 2.65 | 0.1853 | 0.6781 | |
4NV+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 4.79 | 6.39 | 1.31 - 8.27 | 0.06 - 24.15 | 3.42 | 0.79 - 6.07 | 13 | 13 | 0 | 2.71 | 1.97 | 1.64 - 3.78 | 0.5 - 6.2 | 1.72 | 1.22 - 4.6 | 0.2805 | 0.6781 | |
4NV+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 1.68 | 1.31 | 0.97 - 2.39 | 0.07 - 4.48 | 1.38 | 0.81 - 2.15 | 13 | 13 | 0 | 2.21 | 2.39 | 0.91 - 3.51 | 0.17 - 8.03 | 1.35 | 0.46 - 2.5 | 0.4905 | 0.7192 | |
4NV+PD1+ | Abs_Value | 13 | 13 | 0 | 6.47 | 7.25 | 2.53 - 10.41 | 0.15 - 27.06 | 4.9 | 1.31 - 9.5 | 13 | 13 | 0 | 4.92 | 3.56 | 2.98 - 6.86 | 0.76 - 12.63 | 4.21 | 2.41 - 7 | 0.4985 | 0.7192 | |
4NV+TIGIT+ | Abs_Value | 13 | 13 | 0 | 2.85 | 1.84 | 1.85 - 3.85 | 0.19 - 5.28 | 2.47 | 1.65 - 4.98 | 13 | 13 | 0 | 5.08 | 5.67 | 1.99 - 8.16 | 0.51 - 18.1 | 2.26 | 1.08 - 7.52 | 0.198 | 0.6781 | |
4ЕМ | Abs_Value | 13 | 13 | 0 | 83.51 | 154.98 | -0.73 - 167.76 | 1.65 - 581.05 | 33.56 | 14.28 - 75.09 | 13 | 13 | 0 | 17.36 | 26.78 | 2.81 - 31.92 | 1.9 - 101.46 | 8.09 | 3.96 - 16.47 | 0.1538 | 0.6781 | |
4ЕМ_TH1 | Abs_Value | 13 | 13 | 0 | 23.16 | 22.92 | 10.7 - 35.61 | 0.28 - 69.88 | 15.02 | 3.71 - 37.18 | 13 | 13 | 0 | 7.54 | 14.11 | -0.13 - 15.21 | 0.01 - 52.73 | 3.07 | 1.65 - 6.09 | 0.0493 | 0.6781 | |
4ЕМ_TH17 | Abs_Value | 13 | 13 | 0 | 0.03 | 0.03 | 0.01 - 0.05 | 0 - 0.09 | 0.02 | 0 - 0.05 | 13 | 13 | 0 | 0.03 | 0.06 | 0 - 0.06 | 0 - 0.21 | 0.01 | 0 - 0.02 | 0.923 | 0.9601 | |
4ЕМ_Th17TO1 | Abs_Value | 13 | 13 | 0 | 1.88 | 2.85 | 0.33 - 3.43 | 0 - 8.02 | 0.32 | 0.14 - 1.18 | 13 | 13 | 0 | 0.24 | 0.32 | 0.07 - 0.42 | 0 - 1.11 | 0.14 | 0.05 - 0.22 | 0.0621 | 0.6781 | |
4ЕМ_TH2 | Abs_Value | 13 | 13 | 0 | 0.39 | 0.4 | 0.17 - 0.61 | 0.03 - 1.27 | 0.2 | 0.1 - 0.69 | 13 | 13 | 0 | 0.34 | 0.6 | 0.01 - 0.67 | 0.01 - 2.26 | 0.12 | 0.08 - 0.23 | 0.8195 | 0.9094 | |
4ЕМ_TH22 | Abs_Value | 13 | 13 | 0 | 0 | 0 | 0 - 0 | 0 - 0.01 | 0 | 0 - 0 | 13 | 13 | 0 | 0.01 | 0.04 | -0.01 - 0.04 | 0 - 0.16 | 0 | 0 - 0 | 0.4002 | 0.6866 | |
4ЕМ+226+ | Abs_Value | 13 | 13 | 0 | 241.9 | 173.33 | 147.68 - 336.12 | 62.6 - 660.98 | 192.43 | 126 - 371.99 | 13 | 13 | 0 | 156.43 | 96.58 | 103.93 - 208.93 | 36.18 - 318.08 | 115.17 | 96.39 - 232.48 | 0.1371 | 0.6781 | |
4ЕМ+39+ | Abs_Value | 13 | 13 | 0 | 51.04 | 39.02 | 29.83 - 72.26 | 0.65 - 127.55 | 40.86 | 19.93 - 76.25 | 13 | 13 | 0 | 41.88 | 36.21 | 22.2 - 61.56 | 2.04 - 139.13 | 41.5 | 18.65 - 51.06 | 0.5408 | 0.7475 | |
4ЕМ+DR+ | Abs_Value | 13 | 13 | 0 | 143.14 | 130.26 | 72.33 - 213.95 | 24.28 - 526.3 | 98.4 | 72.9 - 188.23 | 13 | 13 | 0 | 73.97 | 53.76 | 44.75 - 103.19 | 14.83 - 210.31 | 58.06 | 41.44 - 85.21 | 0.0958 | 0.6781 | |
4ЕМ+PD1-TIGIT- | Abs_Value | 13 | 13 | 0 | 59.16 | 70.32 | 20.93 - 97.39 | 6.26 - 270.35 | 39.84 | 11.7 - 71.22 | 13 | 13 | 0 | 44.32 | 43.87 | 20.47 - 68.16 | 8.74 - 154.67 | 34.94 | 10.44 - 48.14 | 0.5257 | 0.739 | |
4ЕМ+PD1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 7.95 | 12.5 | 1.15 - 14.75 | 0.32 - 45.6 | 2.72 | 1.4 - 8.4 | 13 | 13 | 0 | 6.49 | 8.26 | 2 - 10.98 | 0.59 - 31.87 | 4.02 | 2.89 - 6.55 | 0.728 | 0.8715 | |
4ЕМ+PD1+ | Abs_Value | 13 | 13 | 0 | 180.81 | 135.5 | 107.15 - 254.46 | 43.74 - 548.64 | 137.64 | 103.09 - 195.8 | 13 | 13 | 0 | 115.38 | 69.07 | 77.83 - 152.93 | 26.83 - 264.13 | 96.95 | 75.64 - 122.6 | 0.1385 | 0.6781 | |
4ЕМ+PD1+TIGIT- | Abs_Value | 13 | 13 | 0 | 99.02 | 55.6 | 68.8 - 129.24 | 23.17 - 193.88 | 90.04 | 75.08 - 118.97 | 13 | 13 | 0 | 67.82 | 46.16 | 42.73 - 92.91 | 19.11 - 155.38 | 55.65 | 36.28 - 64.22 | 0.1331 | 0.6781 | |
4ЕМ+PD1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 81.79 | 88.52 | 33.66 - 129.91 | 20.57 - 354.76 | 58.89 | 33.68 - 100.01 | 13 | 13 | 0 | 47.56 | 30.46 | 31 - 64.12 | 7.72 - 133.76 | 45.49 | 34.65 - 52.2 | 0.2075 | 0.6781 | |
4ЕМ+TIGIT+ | Abs_Value | 13 | 13 | 0 | 89.74 | 99.99 | 35.38 - 144.1 | 22.59 - 400.36 | 65.3 | 34 - 104.03 | 13 | 13 | 0 | 54.05 | 33.34 | 35.92 - 72.17 | 8.33 - 140.74 | 49.17 | 43.44 - 55.09 | 0.2414 | 0.6781 | |
4ЕМTM | Abs_Value | 13 | 13 | 0 | 247.92 | 174.89 | 152.85 - 342.99 | 72.79 - 665.46 | 195.97 | 127.24 - 388.28 | 13 | 13 | 0 | 166.18 | 102.77 | 110.32 - 222.05 | 37.63 - 337 | 124.63 | 100.11 - 239.49 | 0.1623 | 0.6781 | |
4СМ | Abs_Value | 13 | 13 | 0 | 82.66 | 50.33 | 55.3 - 110.01 | 18.35 - 207.67 | 82.63 | 42.12 - 89.44 | 13 | 13 | 0 | 103.94 | 71.91 | 64.85 - 143.03 | 15.91 - 260.46 | 97.48 | 45.2 - 151.85 | 0.3917 | 0.6866 | |
4СМ(СТАР2) | Abs_Value | 13 | 13 | 0 | 65.89 | 37.99 | 45.24 - 86.54 | 15.11 - 150.25 | 71.44 | 33.76 - 85.67 | 13 | 13 | 0 | 78.17 | 54.08 | 48.77 - 107.57 | 21.2 - 184.54 | 63.26 | 33.85 - 106.54 | 0.5101 | 0.7296 | |
4СМ_TH1 | Abs_Value | 13 | 13 | 0 | 3.04 | 2.68 | 1.59 - 4.5 | 0.6 - 9.36 | 2.39 | 1.29 - 3.47 | 13 | 13 | 0 | 6.69 | 8.01 | 2.34 - 11.05 | 0.38 - 30.36 | 4.94 | 1.58 - 9.1 | 0.1408 | 0.6781 | |
4СМ_TH17 | Abs_Value | 13 | 13 | 0 | 8.34 | 3.64 | 6.36 - 10.32 | 3.64 - 15.46 | 8.09 | 5.18 - 10.54 | 13 | 13 | 0 | 12.96 | 11.28 | 6.83 - 19.1 | 1.95 - 34.36 | 9.47 | 3.78 - 16.8 | 0.1806 | 0.6781 | |
4СМ_Th17TO1 | Abs_Value | 13 | 13 | 0 | 1.34 | 1.07 | 0.76 - 1.92 | 0.21 - 3.08 | 1.16 | 0.56 - 1.82 | 13 | 13 | 0 | 2.43 | 2.17 | 1.25 - 3.61 | 0.19 - 8.34 | 2.34 | 1 - 2.67 | 0.1227 | 0.6781 | |
4СМ_TH2 | Abs_Value | 13 | 13 | 0 | 4.14 | 2.3 | 2.89 - 5.4 | 1.33 - 7.78 | 3.88 | 2.09 - 6.68 | 13 | 13 | 0 | 11.09 | 12.08 | 4.52 - 17.65 | 1.16 - 45.88 | 8.49 | 1.29 - 12.84 | 0.0628 | 0.6781 | |
4СМ_TH22 | Abs_Value | 13 | 13 | 0 | 1.19 | 1.56 | 0.34 - 2.04 | 0.11 - 5.84 | 0.58 | 0.35 - 1.17 | 13 | 13 | 0 | 2.43 | 3.58 | 0.48 - 4.38 | 0.06 - 13.33 | 0.87 | 0.72 - 3.09 | 0.2681 | 0.6781 | |
4СМ+226+ | Abs_Value | 13 | 13 | 0 | 63.24 | 36.6 | 43.34 - 83.13 | 14.8 - 144.2 | 68.05 | 31.79 - 79.68 | 13 | 13 | 0 | 74.53 | 51.68 | 46.43 - 102.62 | 19.64 - 178.97 | 60.07 | 32.98 - 98.97 | 0.5272 | 0.739 | |
4СМ+39+ | Abs_Value | 13 | 13 | 0 | 14.91 | 11.7 | 8.55 - 21.26 | 0.06 - 40.39 | 12.19 | 7.06 - 23.23 | 13 | 13 | 0 | 21.13 | 30.82 | 4.37 - 37.88 | 0.51 - 118.64 | 13.06 | 6.43 - 21.8 | 0.5064 | 0.7264 | |
4СМ+DR+ | Abs_Value | 13 | 13 | 0 | 14.01 | 13.93 | 6.44 - 21.58 | 3.76 - 45.11 | 7.05 | 5.05 - 14.82 | 13 | 13 | 0 | 20.3 | 19.59 | 9.65 - 30.95 | 3.93 - 64.82 | 10.94 | 7.81 - 24.58 | 0.3556 | 0.6781 | |
4СМ+PD1-TIGIT- | Abs_Value | 13 | 13 | 0 | 20.25 | 14.14 | 12.57 - 27.94 | 4.29 - 55.03 | 18.98 | 7.57 - 25.24 | 13 | 13 | 0 | 27.33 | 20.43 | 16.22 - 38.43 | 2.11 - 68.44 | 22.11 | 12.3 - 37.2 | 0.3161 | 0.6781 | |
4СМ+PD1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 3.66 | 4.04 | 1.46 - 5.86 | 0.36 - 15.7 | 2.8 | 1.36 - 3.88 | 13 | 13 | 0 | 4.74 | 3.84 | 2.65 - 6.82 | 0.21 - 13.54 | 4.14 | 1.62 - 6.43 | 0.4918 | 0.7192 | |
4СМ+PD1+ | Abs_Value | 13 | 13 | 0 | 41.98 | 30.47 | 25.41 - 58.54 | 9.99 - 123.91 | 42.49 | 20.33 - 50.99 | 13 | 13 | 0 | 46.1 | 35.48 | 26.81 - 65.39 | 3.36 - 122.72 | 37.27 | 22.3 - 73.22 | 0.7533 | 0.884 | |
4СМ+PD1+TIGIT- | Abs_Value | 13 | 13 | 0 | 16.12 | 9.75 | 10.82 - 21.42 | 3.23 - 31.56 | 17.02 | 6.71 - 24.01 | 13 | 13 | 0 | 17.93 | 14.88 | 9.84 - 26.02 | 1.56 - 55.65 | 13.15 | 8.49 - 25.36 | 0.7172 | 0.867 | |
4СМ+PD1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 25.86 | 22.41 | 13.68 - 38.04 | 5.36 - 92.35 | 26.08 | 10.22 - 29.56 | 13 | 13 | 0 | 28.18 | 21.56 | 16.45 - 39.9 | 1.8 - 67.07 | 20.7 | 16.4 - 42.34 | 0.7908 | 0.9 | |
4СМ+TIGIT+ | Abs_Value | 13 | 13 | 0 | 29.52 | 23.78 | 16.6 - 42.45 | 6.2 - 97.93 | 28.45 | 12.82 - 35.43 | 13 | 13 | 0 | 32.91 | 24.07 | 19.83 - 46 | 4.81 - 74.86 | 22.06 | 20.58 - 48.77 | 0.7209 | 0.8691 | |
4ТM_TH1 | Abs_Value | 13 | 13 | 0 | 23.31 | 14.47 | 15.45 - 31.18 | 3.7 - 54.39 | 19.8 | 12 - 27.68 | 13 | 13 | 0 | 17.67 | 22.34 | 5.53 - 29.81 | 0.31 - 88.8 | 12.46 | 6.04 - 17.61 | 0.4532 | 0.7124 | |
4ТM_TH17 | Abs_Value | 13 | 13 | 0 | 10.76 | 7.93 | 6.45 - 15.07 | 1.32 - 26.41 | 6.78 | 5.51 - 14.52 | 13 | 13 | 0 | 17.44 | 20.5 | 6.3 - 28.58 | 2.44 - 68.85 | 11.71 | 5.53 - 16.7 | 0.2899 | 0.6781 | |
4ТM_Th17TO1 | Abs_Value | 13 | 13 | 0 | 8.52 | 7.97 | 4.19 - 12.86 | 1.35 - 28.42 | 5.41 | 3.78 - 9.57 | 13 | 13 | 0 | 8.54 | 9.73 | 3.25 - 13.83 | 0.13 - 35.59 | 6.45 | 2.87 - 9.11 | 0.9959 | 0.9959 | |
4ТM_TH2 | Abs_Value | 13 | 13 | 0 | 5.43 | 6.04 | 2.14 - 8.71 | 0.67 - 19.04 | 2.96 | 1.96 - 4.7 | 13 | 13 | 0 | 9.45 | 10.03 | 4 - 14.91 | 0.77 - 33.45 | 3.13 | 1.44 - 15.46 | 0.2299 | 0.6781 | |
4ТM_TH22 | Abs_Value | 13 | 13 | 0 | 7.06 | 6.43 | 3.56 - 10.56 | 0.34 - 22.69 | 6.47 | 2.19 - 8.34 | 13 | 13 | 0 | 9.1 | 10.7 | 3.28 - 14.91 | 1.11 - 38.35 | 4.1 | 2.72 - 13.99 | 0.563 | 0.7507 | |
4ТREG | Abs_Value | 13 | 13 | 0 | 2.67 | 3.56 | 0.73 - 4.6 | 0.18 - 14.06 | 1.89 | 0.91 - 2.05 | 13 | 13 | 0 | 3.25 | 3.83 | 1.17 - 5.33 | 0.49 - 13.02 | 1.36 | 1.12 - 3.25 | 0.6927 | 0.8514 | |
4ТREG(СТАР2) | Abs_Value | 13 | 13 | 0 | 166.74 | 142.02 | 89.54 - 243.94 | 52.54 - 539.05 | 122.66 | 94.71 - 157.59 | 13 | 13 | 0 | 176.73 | 132 | 104.98 - 248.49 | 45.87 - 554.23 | 125.25 | 100.3 - 206.41 | 0.8542 | 0.9205 | |
4ТREG_TH1 | Abs_Value | 13 | 13 | 0 | 0.34 | 0.18 | 0.25 - 0.44 | 0.12 - 0.68 | 0.26 | 0.23 - 0.45 | 13 | 13 | 0 | 0.36 | 0.37 | 0.16 - 0.56 | 0.09 - 1.26 | 0.19 | 0.14 - 0.39 | 0.8509 | 0.9201 | |
4ТREG_TH17 | Abs_Value | 13 | 13 | 0 | 4.58 | 3.04 | 2.93 - 6.24 | 1.23 - 13.43 | 4.22 | 2.99 - 5.13 | 13 | 13 | 0 | 6.46 | 4.28 | 4.13 - 8.79 | 2.62 - 15.15 | 4.65 | 3.37 - 7.8 | 0.2109 | 0.6781 | |
4ТREG_Th17TO1 | Abs_Value | 13 | 13 | 0 | 0.1 | 0.09 | 0.05 - 0.14 | 0.02 - 0.3 | 0.06 | 0.03 - 0.16 | 13 | 13 | 0 | 0.15 | 0.14 | 0.07 - 0.22 | 0 - 0.38 | 0.06 | 0.05 - 0.23 | 0.2956 | 0.6781 | |
4ТREG_TH2 | Abs_Value | 13 | 13 | 0 | 2.41 | 1.05 | 1.84 - 2.99 | 1.11 - 4.61 | 2.24 | 1.58 - 3.13 | 13 | 13 | 0 | 2.79 | 1.48 | 1.99 - 3.59 | 1.05 - 6.08 | 3.1 | 1.6 - 3.72 | 0.462 | 0.7142 | |
4ТREG_TH22 | Abs_Value | 13 | 13 | 0 | 6.66 | 9.3 | 1.6 - 11.71 | 0.91 - 36.5 | 4.71 | 1.83 - 7.21 | 13 | 13 | 0 | 5.61 | 4.82 | 2.98 - 8.23 | 1.59 - 16.79 | 3.95 | 3.02 - 5.3 | 0.7225 | 0.8691 | |
4ТЕ | Abs_Value | 13 | 13 | 0 | 25.68 | 28.83 | 10.01 - 41.35 | 0.7 - 97.53 | 14.36 | 5.41 - 36.71 | 13 | 13 | 0 | 21.25 | 36.25 | 1.54 - 40.95 | 0.66 - 114.7 | 6.81 | 1.17 - 15.4 | 0.7331 | 0.8733 | |
4ТЕ(СТАР2) | Abs_Value | 13 | 13 | 0 | 69.3 | 56.53 | 38.57 - 100.03 | 21.6 - 217.76 | 46.95 | 33.64 - 77.25 | 13 | 13 | 0 | 64.29 | 62.48 | 30.33 - 98.26 | 11.38 - 207.55 | 49.68 | 22.31 - 72.87 | 0.8323 | 0.91 | |
4ТЕ_TH1 | Abs_Value | 13 | 13 | 0 | 6.79 | 6.41 | 3.31 - 10.27 | 0.05 - 20.2 | 3.66 | 1.66 - 10.59 | 13 | 13 | 0 | 7.37 | 15.9 | -1.27 - 16.01 | 0.01 - 52.19 | 0.58 | 0.33 - 3.53 | 0.9044 | 0.9546 | |
4ТЕ_TH17 | Abs_Value | 13 | 13 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.04 | 0 | 0 - 0.01 | 13 | 13 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.01 | 0.01 | 0 - 0.01 | 0.4966 | 0.7192 | |
4ТЕ_Th17TO1 | Abs_Value | 13 | 13 | 0 | 0.19 | 0.26 | 0.05 - 0.33 | 0 - 0.76 | 0.05 | 0.02 - 0.21 | 13 | 13 | 0 | 0.13 | 0.23 | 0 - 0.25 | 0 - 0.78 | 0.02 | 0 - 0.15 | 0.5389 | 0.7475 | |
4ТЕ_TH2 | Abs_Value | 13 | 13 | 0 | 0.2 | 0.24 | 0.07 - 0.33 | 0.01 - 0.83 | 0.11 | 0.04 - 0.35 | 13 | 13 | 0 | 0.44 | 0.72 | 0.05 - 0.82 | 0 - 2.33 | 0.16 | 0.03 - 0.27 | 0.2834 | 0.6781 | |
4ТЕ_TH22 | Abs_Value | 13 | 13 | 0 | 0.01 | 0.01 | 0 - 0.02 | 0 - 0.05 | 0 | 0 - 0.02 | 13 | 13 | 0 | 0 | 0.01 | 0 - 0.01 | 0 - 0.02 | 0 | 0 - 0 | 0.2025 | 0.6781 | |
4ТЕ+226+ | Abs_Value | 13 | 13 | 0 | 65.9 | 56.15 | 35.37 - 96.42 | 17.35 - 215.7 | 42.5 | 29.7 - 75.76 | 13 | 13 | 0 | 59.23 | 61.82 | 25.62 - 92.84 | 10.21 - 202.6 | 44.9 | 16.88 - 66.16 | 0.776 | 0.8962 | |
4ТЕ+39+ | Abs_Value | 13 | 13 | 0 | 5.97 | 3.71 | 3.96 - 7.99 | 0.43 - 11.93 | 5.87 | 3.68 - 7.92 | 13 | 13 | 0 | 8.84 | 10.79 | 2.97 - 14.7 | 0.21 - 33.74 | 4.21 | 2.04 - 10.76 | 0.3801 | 0.6866 | |
4ТЕ+DR+ | Abs_Value | 13 | 13 | 0 | 42.24 | 43.71 | 18.48 - 66 | 5.42 - 168.72 | 28.9 | 15.47 - 52.93 | 13 | 13 | 0 | 33.35 | 48.35 | 7.07 - 59.63 | 3.27 - 156.97 | 11.63 | 6.03 - 29.26 | 0.6274 | 0.7976 | |
4ТЕ+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 21.71 | 21.28 | 10.14 - 33.28 | 4.28 - 78.19 | 11.57 | 8.36 - 33.76 | 13 | 13 | 0 | 31.59 | 38.22 | 10.81 - 52.37 | 1.94 - 132.13 | 15.24 | 6.25 - 29.36 | 0.4258 | 0.7016 | |
4ТЕ+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 3.64 | 4.06 | 1.43 - 5.85 | 0.48 - 16.23 | 2.38 | 1.68 - 3.48 | 13 | 13 | 0 | 3.28 | 3.04 | 1.63 - 4.94 | 0.35 - 11.49 | 2.91 | 0.97 - 3.98 | 0.802 | 0.9009 | |
4ТЕ+PD-1+ | Abs_Value | 13 | 13 | 0 | 43.94 | 41.38 | 21.45 - 66.44 | 5.49 - 162.5 | 35.01 | 19.7 - 60.4 | 13 | 13 | 0 | 29.42 | 25.64 | 15.48 - 43.36 | 4.99 - 90 | 15.98 | 11.62 - 37.85 | 0.2949 | 0.6781 | |
4ТЕ+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 26.62 | 24.8 | 13.14 - 40.11 | 2.04 - 86.28 | 19.27 | 8.78 - 45.33 | 13 | 13 | 0 | 19.02 | 19.62 | 8.35 - 29.69 | 1.62 - 67.21 | 10.7 | 5.15 - 25.97 | 0.395 | 0.6866 | |
4ТЕ+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 17.32 | 19.33 | 6.81 - 27.83 | 3.45 - 76.22 | 13.34 | 5.89 - 15.88 | 13 | 13 | 0 | 10.4 | 7.98 | 6.06 - 14.74 | 2.91 - 25.6 | 9.16 | 3.58 - 14.14 | 0.2503 | 0.6781 | |
4ТЕ+TIGIT+ | Abs_Value | 13 | 13 | 0 | 20.96 | 23.17 | 8.36 - 33.56 | 6.37 - 92.45 | 14.32 | 7.06 - 18.99 | 13 | 13 | 0 | 13.68 | 10.38 | 8.04 - 19.33 | 3.26 - 34.28 | 10.04 | 4.92 - 17.05 | 0.3162 | 0.6781 | |
4ТМ | Abs_Value | 13 | 13 | 0 | 165.75 | 92.33 | 115.55 - 215.94 | 55.5 - 339.62 | 164.24 | 81.42 - 247.66 | 13 | 13 | 0 | 141.19 | 99.78 | 86.95 - 195.42 | 36.46 - 328.01 | 100.61 | 81.37 - 204.29 | 0.521 | 0.7387 | |
8+ | Abs_Value | 13 | 13 | 0 | 973.01 | 747.72 | 566.54 - 1379.47 | 57.71 - 2452.07 | 696.99 | 568.49 - 1161.65 | 13 | 13 | 0 | 546.63 | 640.27 | 198.58 - 894.69 | 80.74 - 2238.8 | 261.13 | 202.41 - 598.49 | 0.1318 | 0.6781 | |
8+ (IM STAT) | Abs_Value | 13 | 13 | 0 | 1085.12 | 786.37 | 657.64 - 1512.59 | 70.67 - 2683.52 | 803.31 | 580.14 - 1328.08 | 13 | 13 | 0 | 682.26 | 755.81 | 271.4 - 1093.12 | 101.71 - 2673.64 | 370.08 | 238.86 - 856.27 | 0.1955 | 0.6781 | |
8+226+ | Abs_Value | 13 | 13 | 0 | 1425.23 | 900.19 | 935.88 - 1914.58 | 104.01 - 3338.48 | 1387.98 | 879.96 - 1695.87 | 13 | 13 | 0 | 897.07 | 877.53 | 420.04 - 1374.1 | 239.21 - 3240.63 | 640.91 | 367.77 - 988.26 | 0.1429 | 0.6781 | |
8+39+ | Abs_Value | 13 | 13 | 0 | 149.18 | 125.68 | 80.86 - 217.5 | 6.69 - 401.66 | 156.01 | 25.68 - 185.72 | 13 | 13 | 0 | 124.59 | 156.16 | 39.7 - 209.48 | 3.22 - 554.73 | 73.44 | 39.08 - 132.9 | 0.6625 | 0.8273 | |
8+DR+ | Abs_Value | 13 | 13 | 0 | 974.76 | 581.03 | 658.91 - 1290.61 | 77.9 - 2000.24 | 936.64 | 510.81 - 1096.91 | 13 | 13 | 0 | 655.65 | 764.95 | 239.82 - 1071.49 | 43.35 - 2729.41 | 426.73 | 213.57 - 575.13 | 0.2435 | 0.6781 | |
8+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 507.33 | 502.02 | 234.43 - 780.23 | 38.12 - 1570.48 | 378.56 | 162 - 611.39 | 13 | 13 | 0 | 333.33 | 368.67 | 132.92 - 533.73 | 70.59 - 1371.15 | 188.7 | 106.63 - 341.99 | 0.3247 | 0.6781 | |
8+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 417.34 | 339.24 | 232.92 - 601.75 | 74.35 - 1183.71 | 385.59 | 155.15 - 548.77 | 13 | 13 | 0 | 350.04 | 412.25 | 125.94 - 574.14 | 10.16 - 1209.08 | 151.69 | 95.73 - 384 | 0.6537 | 0.8226 | |
8+PD-1+ | Abs_Value | 13 | 13 | 0 | 558.18 | 542.33 | 263.36 - 852.99 | 49.89 - 2097 | 491.09 | 237.65 - 612.58 | 13 | 13 | 0 | 305.61 | 194.81 | 199.71 - 411.51 | 93.13 - 731.94 | 253.18 | 149.01 - 438.12 | 0.1348 | 0.6781 | |
8+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 185.76 | 205.22 | 74.2 - 297.32 | 9.05 - 678.2 | 96.85 | 71.47 - 262.8 | 13 | 13 | 0 | 96.17 | 103.78 | 39.75 - 152.58 | 10.94 - 364.07 | 60.93 | 36.55 - 101.92 | 0.1774 | 0.6781 | |
8+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 372.41 | 395.78 | 157.27 - 587.56 | 40.84 - 1584.15 | 337.51 | 134.58 - 412.25 | 13 | 13 | 0 | 209.44 | 130.02 | 138.76 - 280.12 | 47.09 - 434.48 | 141.45 | 123.92 - 304.44 | 0.1794 | 0.6781 | |
8+TIGIT+ | Abs_Value | 13 | 13 | 0 | 789.75 | 541.86 | 495.19 - 1084.31 | 115.8 - 2034.4 | 738.06 | 518.85 - 986.73 | 13 | 13 | 0 | 559.48 | 510.03 | 282.22 - 836.74 | 57.24 - 1576.95 | 372.8 | 202.83 - 818.49 | 0.2756 | 0.6781 | |
8EMTM | Abs_Value | 13 | 13 | 0 | 347.92 | 377.57 | 142.67 - 553.16 | 47.77 - 1398.17 | 228.63 | 102.82 - 403.3 | 13 | 13 | 0 | 121.21 | 97.04 | 68.46 - 173.96 | 13.51 - 335.18 | 95.26 | 39.69 - 172.92 | 0.0553 | 0.6781 | |
8EMTM+226+ | Abs_Value | 13 | 13 | 0 | 337.02 | 376.23 | 132.5 - 541.54 | 28.26 - 1379.5 | 194.8 | 96.04 - 400.41 | 13 | 13 | 0 | 103.51 | 83.81 | 57.95 - 149.07 | 9.76 - 283.7 | 83.19 | 35.2 - 160.55 | 0.0476 | 0.6781 | |
8EMTM+39+ | Abs_Value | 13 | 13 | 0 | 48.82 | 39.13 | 27.55 - 70.09 | 0.18 - 109.55 | 59.12 | 5.97 - 71.91 | 13 | 13 | 0 | 21.96 | 19.26 | 11.49 - 32.43 | 0.97 - 52.65 | 22.44 | 4.66 - 39.32 | 0.0398 | 0.6781 | |
8EMTM+DR+ | Abs_Value | 13 | 13 | 0 | 255.33 | 238.84 | 125.5 - 385.16 | 34.54 - 830.52 | 168.04 | 77.85 - 362.11 | 13 | 13 | 0 | 95.55 | 84.09 | 49.84 - 141.26 | 9.62 - 298.35 | 72.75 | 36.73 - 130.68 | 0.0381 | 0.6781 | |
8EMTM+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 139.91 | 302.81 | -24.7 - 304.51 | 4.45 - 1106.11 | 38.89 | 21.54 - 55.16 | 13 | 13 | 0 | 31.53 | 32.99 | 13.6 - 49.47 | 3.23 - 96.46 | 18.1 | 11.17 - 41.75 | 0.2232 | 0.6781 | |
8EMTM+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 74.21 | 86.1 | 27.4 - 121.01 | 7.63 - 242.77 | 24.48 | 12.4 - 102.51 | 13 | 13 | 0 | 27.79 | 34.5 | 9.04 - 46.55 | 0.5 - 119.96 | 8.44 | 5.38 - 32.25 | 0.0904 | 0.6781 | |
8EMTM+PD-1+ | Abs_Value | 13 | 13 | 0 | 133.8 | 119.06 | 69.08 - 198.52 | 26.27 - 466.71 | 113.35 | 50.13 - 177.14 | 13 | 13 | 0 | 61.88 | 40.26 | 40 - 83.77 | 9.78 - 119.51 | 46.3 | 25.86 - 100.57 | 0.0572 | 0.6781 | |
8EMTM+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 48.19 | 71.54 | 9.31 - 87.08 | 4.29 - 268.37 | 24.49 | 11.08 - 37.34 | 13 | 13 | 0 | 16.93 | 15.96 | 8.25 - 25.6 | 4.23 - 56.1 | 10.28 | 5.44 - 19.35 | 0.1477 | 0.6781 | |
8EMTM+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 85.61 | 60.36 | 52.8 - 118.42 | 18.92 - 198.34 | 51.77 | 42.13 - 115.72 | 13 | 13 | 0 | 44.95 | 33.54 | 26.72 - 63.19 | 5.55 - 107.53 | 34.48 | 20.57 - 61.05 | 0.0473 | 0.6781 | |
8EMTM+TIGIT+ | Abs_Value | 13 | 13 | 0 | 159.81 | 106.94 | 101.68 - 217.95 | 28.09 - 300.85 | 188.17 | 51.37 - 267.22 | 13 | 13 | 0 | 72.75 | 63.36 | 38.31 - 107.19 | 6.05 - 220.12 | 65.96 | 25.68 - 91.65 | 0.0203 | 0.6781 | |
8NV | Abs_Value | 13 | 13 | 0 | 45.79 | 28.32 | 30.4 - 61.18 | 8.16 - 95.21 | 33.84 | 25.59 - 65.7 | 13 | 13 | 0 | 58.65 | 50.58 | 31.15 - 86.14 | 4.62 - 189.4 | 63.06 | 19.96 - 75.23 | 0.4339 | 0.7016 | |
8NV(СТАР2) | Abs_Value | 13 | 13 | 0 | 33.1 | 22.31 | 20.97 - 45.23 | 3.18 - 72.59 | 32.88 | 19.17 - 37.83 | 13 | 13 | 0 | 67.91 | 68.16 | 30.86 - 104.96 | 4.23 - 232.76 | 53.18 | 17.68 - 97.88 | 0.1012 | 0.6781 | |
8NV+226+ | Abs_Value | 13 | 13 | 0 | 27.93 | 18.66 | 17.79 - 38.07 | 3.13 - 63.08 | 28.59 | 13.02 - 32.37 | 13 | 13 | 0 | 57.09 | 62.6 | 23.06 - 91.12 | 3.16 - 230.07 | 42.18 | 16.37 - 86.19 | 0.1296 | 0.6781 | |
8NV+39+ | Abs_Value | 13 | 13 | 0 | 1.43 | 1.01 | 0.88 - 1.97 | 0.03 - 3.49 | 1.2 | 0.63 - 2.01 | 13 | 13 | 0 | 6.03 | 8.56 | 1.38 - 10.68 | 0.15 - 30.4 | 1.66 | 0.7 - 8.3 | 0.0776 | 0.6781 | |
8NV+DR+ | Abs_Value | 13 | 13 | 0 | 2.85 | 1.73 | 1.91 - 3.79 | 0.61 - 5.76 | 3.32 | 1.55 - 3.99 | 13 | 13 | 0 | 12.46 | 20.78 | 1.17 - 23.76 | 0.52 - 79.65 | 6.78 | 2.29 - 11.12 | 0.122 | 0.6781 | |
8NV+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 26.32 | 19.51 | 15.71 - 36.93 | 1.66 - 66.52 | 23.52 | 13.57 - 31.19 | 13 | 13 | 0 | 46.66 | 61.95 | 12.99 - 80.34 | 1.58 - 223.18 | 27.39 | 5.68 - 64.64 | 0.2772 | 0.6781 | |
8NV+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 2.68 | 3.16 | 0.96 - 4.41 | 0.41 - 11.42 | 1.59 | 0.81 - 2.43 | 13 | 13 | 0 | 13.29 | 33.02 | -4.65 - 31.24 | 0.08 - 122.5 | 4.44 | 0.7 - 7.9 | 0.2708 | 0.6781 | |
8NV+PD-1+ | Abs_Value | 13 | 13 | 0 | 4.1 | 4 | 1.92 - 6.27 | 0.06 - 14.35 | 3.65 | 1.11 - 5.19 | 13 | 13 | 0 | 7.95 | 6.45 | 4.45 - 11.46 | 0.97 - 19.52 | 7.03 | 1.76 - 13.46 | 0.0818 | 0.6781 | |
8NV+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 1.92 | 2.63 | 0.49 - 3.35 | 0 - 9.29 | 1.1 | 0.26 - 2.14 | 13 | 13 | 0 | 2.55 | 4.08 | 0.33 - 4.76 | 0.01 - 12.11 | 0.95 | 0.33 - 1.92 | 0.6453 | 0.8141 | |
8NV+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 2.18 | 1.69 | 1.26 - 3.1 | 0.06 - 5.06 | 2.04 | 0.57 - 3.18 | 13 | 13 | 0 | 5.41 | 5.98 | 2.16 - 8.66 | 0.22 - 17.65 | 2.61 | 0.96 - 7.01 | 0.0823 | 0.6781 | |
8NV+TIGIT+ | Abs_Value | 13 | 13 | 0 | 4.86 | 3.3 | 3.07 - 6.66 | 0.78 - 11.87 | 4.46 | 2.67 - 5.87 | 13 | 13 | 0 | 18.7 | 37.34 | -1.59 - 39 | 0.34 - 140.04 | 7 | 2.51 - 15.5 | 0.2075 | 0.6781 | |
8TREG | Abs_Value | 13 | 13 | 0 | 965.31 | 737.01 | 564.66 - 1365.95 | 59.02 - 2419.83 | 706.42 | 583.47 - 1219.41 | 13 | 13 | 0 | 556.75 | 632.79 | 212.76 - 900.74 | 76.34 - 2160.15 | 285.5 | 205.13 - 632.61 | 0.1428 | 0.6781 | |
8ЕМ | Abs_Value | 13 | 13 | 0 | 311.07 | 295.94 | 150.2 - 471.94 | 24.53 - 949.3 | 173.01 | 112.84 - 509.36 | 13 | 13 | 0 | 94.72 | 105.65 | 37.29 - 152.15 | 9.71 - 355.83 | 43.06 | 20.95 - 153.4 | 0.0254 | 0.6781 | |
8СМ | Abs_Value | 13 | 13 | 0 | 15.13 | 15.6 | 6.65 - 23.61 | 1.96 - 50.29 | 7.37 | 6.27 - 22.09 | 13 | 13 | 0 | 30.87 | 44.13 | 6.88 - 54.86 | 1.67 - 142.48 | 10.98 | 7.36 - 18.61 | 0.2441 | 0.6781 | |
8СМ(СТАР2) | Abs_Value | 13 | 13 | 0 | 11.88 | 13.94 | 4.3 - 19.46 | 1.34 - 46.77 | 7.23 | 3.84 - 11.07 | 13 | 13 | 0 | 16.92 | 18.98 | 6.6 - 27.24 | 0.7 - 60.65 | 7.86 | 4.01 - 18.59 | 0.4483 | 0.7069 | |
8СМ+226+ | Abs_Value | 13 | 13 | 0 | 10.47 | 12.38 | 3.74 - 17.2 | 1.34 - 39.93 | 6.41 | 3.65 - 8.63 | 13 | 13 | 0 | 12.1 | 13.57 | 4.72 - 19.47 | 0.67 - 48.69 | 5.72 | 3.42 - 14.13 | 0.7518 | 0.884 | |
8СМ+39+ | Abs_Value | 13 | 13 | 0 | 3.33 | 5.24 | 0.48 - 6.18 | 0.01 - 19.68 | 1.82 | 0.38 - 2.84 | 13 | 13 | 0 | 6.07 | 12.52 | -0.73 - 12.88 | 0.09 - 46.33 | 1.96 | 0.45 - 3.22 | 0.4763 | 0.7185 | |
8СМ+DR+ | Abs_Value | 13 | 13 | 0 | 8.74 | 11.98 | 2.23 - 15.25 | 0.88 - 44.36 | 4.53 | 2.55 - 7.74 | 13 | 13 | 0 | 13.2 | 16.24 | 4.37 - 22.02 | 0.31 - 51.36 | 5.17 | 2.6 - 14.49 | 0.4346 | 0.7016 | |
8СМ+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 2.9 | 5.41 | -0.04 - 5.84 | 0.16 - 20.49 | 1.44 | 0.48 - 2.54 | 13 | 13 | 0 | 1.96 | 1.61 | 1.08 - 2.84 | 0.4 - 5.04 | 1.23 | 0.74 - 3.13 | 0.5569 | 0.7482 | |
8СМ+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 2.07 | 2.82 | 0.54 - 3.6 | 0.33 - 11.01 | 1.15 | 0.76 - 2.16 | 13 | 13 | 0 | 2.86 | 3.64 | 0.88 - 4.84 | 0.03 - 10.87 | 1.04 | 0.69 - 2.58 | 0.5424 | 0.7475 | |
8СМ+PD-1+ | Abs_Value | 13 | 13 | 0 | 6.91 | 11.09 | 0.87 - 12.94 | 0.1 - 42.6 | 3.62 | 2.28 - 6.34 | 13 | 13 | 0 | 12.1 | 14.82 | 4.04 - 20.16 | 0.27 - 50.7 | 4.48 | 3.17 - 15.62 | 0.3226 | 0.6781 | |
8СМ+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 0.93 | 1.19 | 0.28 - 1.57 | 0.01 - 3.85 | 0.47 | 0.36 - 0.73 | 13 | 13 | 0 | 0.97 | 1.09 | 0.38 - 1.57 | 0.02 - 3.03 | 0.37 | 0.36 - 1.87 | 0.9152 | 0.956 | |
8СМ+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 5.98 | 10.14 | 0.47 - 11.49 | 0.09 - 38.76 | 3.15 | 1.56 - 5.57 | 13 | 13 | 0 | 11.13 | 14.46 | 3.27 - 18.98 | 0.21 - 48.83 | 4.1 | 2.81 - 13.11 | 0.305 | 0.6781 | |
8СМ+TIGIT+ | Abs_Value | 13 | 13 | 0 | 8.05 | 10.57 | 2.31 - 13.8 | 0.84 - 40.38 | 4.83 | 1.89 - 7.96 | 13 | 13 | 0 | 13.99 | 17.4 | 4.53 - 23.44 | 0.24 - 54.85 | 6.27 | 3.21 - 14.15 | 0.3057 | 0.6781 | |
8ТЕ | Abs_Value | 13 | 13 | 0 | 869.23 | 644.32 | 518.97 - 1219.49 | 48.7 - 2173 | 678.5 | 416.74 - 1057.9 | 13 | 13 | 0 | 606.45 | 793.52 | 175.08 - 1037.81 | 134.4 - 2935.15 | 219.33 | 198.73 - 688.04 | 0.3636 | 0.6856 | |
8ТЕ(СТАР2) | Abs_Value | 13 | 13 | 0 | 1088.37 | 788.89 | 659.52 - 1517.21 | 93.35 - 2737.76 | 862.07 | 555.03 - 1157.21 | 13 | 13 | 0 | 781.56 | 896.57 | 294.18 - 1268.94 | 166.03 - 3213.82 | 433.23 | 252.42 - 870.46 | 0.3637 | 0.6856 | |
8ТЕ+226+ | Abs_Value | 13 | 13 | 0 | 1049.05 | 777.66 | 626.31 - 1471.8 | 61.08 - 2644.03 | 809.38 | 490.38 - 1109.6 | 13 | 13 | 0 | 723.53 | 873.45 | 248.72 - 1198.35 | 102.22 - 3154.74 | 330.69 | 241 - 755.51 | 0.3257 | 0.6781 | |
8ТЕ+39+ | Abs_Value | 13 | 13 | 0 | 95.14 | 95.05 | 43.47 - 146.81 | 6 - 323.26 | 59.84 | 17.3 - 125.59 | 13 | 13 | 0 | 89.92 | 138.94 | 14.4 - 165.45 | 0.86 - 469.2 | 34.47 | 19.83 - 82.62 | 0.912 | 0.956 | |
8ТЕ+DR+ | Abs_Value | 13 | 13 | 0 | 708.11 | 502.81 | 434.78 - 981.44 | 41.33 - 1775.21 | 735.53 | 301.99 - 890.82 | 13 | 13 | 0 | 533.66 | 738.23 | 132.35 - 934.97 | 21.59 - 2669.82 | 281.95 | 170.74 - 471.59 | 0.489 | 0.7192 | |
8ТЕ+PD-1-TIGIT- | Abs_Value | 13 | 13 | 0 | 337.96 | 331 | 158.02 - 517.9 | 15.42 - 1169.4 | 281.68 | 96.42 - 398.93 | 13 | 13 | 0 | 252.89 | 368.08 | 52.79 - 452.98 | 20.48 - 1323.33 | 90.82 | 75.37 - 235.12 | 0.5414 | 0.7475 | |
8ТЕ+PD-1-TIGIT+ | Abs_Value | 13 | 13 | 0 | 336.82 | 282.52 | 183.24 - 490.4 | 55.35 - 990.18 | 230.35 | 129.05 - 524.75 | 13 | 13 | 0 | 305.71 | 393.99 | 91.53 - 519.88 | 9.5 - 1190.46 | 115.13 | 84.56 - 360.57 | 0.8192 | 0.9094 | |
8ТЕ+PD-1+ | Abs_Value | 13 | 13 | 0 | 413.59 | 484.86 | 150.01 - 677.16 | 22.59 - 1901.19 | 292.97 | 194.23 - 413.6 | 13 | 13 | 0 | 222.97 | 188.23 | 120.64 - 325.29 | 35.09 - 700.03 | 158.31 | 79.05 - 286.81 | 0.2055 | 0.6781 | |
8ТЕ+PD-1+TIGIT- | Abs_Value | 13 | 13 | 0 | 134.91 | 151.57 | 52.51 - 217.3 | 3.74 - 471.95 | 77.76 | 39.32 - 156.96 | 13 | 13 | 0 | 75.64 | 97.57 | 22.6 - 128.69 | 5.67 - 353.82 | 34.83 | 20.61 - 91.8 | 0.2494 | 0.6781 | |
8ТЕ+PD-1+TIGIT+ | Abs_Value | 13 | 13 | 0 | 278.68 | 365.98 | 79.73 - 477.63 | 17.97 - 1429.23 | 170.79 | 92.76 - 256.65 | 13 | 13 | 0 | 147.32 | 116.29 | 84.1 - 210.54 | 29.42 - 357.6 | 97.13 | 47.51 - 213.88 | 0.2372 | 0.6781 | |
8ТЕ+TIGIT+ | Abs_Value | 13 | 13 | 0 | 615.5 | 501.71 | 342.77 - 888.24 | 73.32 - 1866.88 | 534.52 | 260.99 - 702.42 | 13 | 13 | 0 | 453.03 | 479.73 | 192.25 - 713.81 | 50.85 - 1536.67 | 255.67 | 138.62 - 699.97 | 0.4071 | 0.6902 | |
8ТМ | Abs_Value | 13 | 13 | 0 | 91.97 | 114.04 | 29.98 - 153.97 | 8.37 - 434.09 | 50.69 | 27.35 - 101.77 | 13 | 13 | 0 | 40.32 | 29.2 | 24.44 - 56.19 | 7.07 - 92.45 | 41.07 | 15.16 - 59.97 | 0.1366 | 0.6781 | |
TREG_CM | Abs_Value | 13 | 13 | 0 | 2.42 | 1.84 | 1.42 - 3.42 | 0.14 - 6.15 | 2.01 | 1.33 - 2.54 | 13 | 13 | 0 | 2.71 | 1.9 | 1.68 - 3.74 | 0.28 - 6.58 | 2.28 | 1.11 - 3.81 | 0.6901 | 0.8514 | |
TREG_EMTM | Abs_Value | 13 | 13 | 0 | 24.38 | 24.24 | 11.2 - 37.55 | 5.53 - 99.28 | 18.31 | 13.69 - 22.04 | 13 | 13 | 0 | 25.58 | 19.9 | 14.76 - 36.39 | 7.98 - 69.64 | 17.52 | 13.91 - 21.39 | 0.8914 | 0.9432 | |
TREG_NV | Abs_Value | 13 | 13 | 0 | 3.55 | 3.84 | 1.47 - 5.64 | 0.06 - 14.23 | 1.97 | 0.89 - 5.29 | 13 | 13 | 0 | 2.64 | 2.1 | 1.5 - 3.79 | 0.25 - 6.8 | 2.13 | 1.02 - 3.33 | 0.4631 | 0.7142 | |
TREG_TE | Abs_Value | 13 | 13 | 0 | 4.21 | 2.25 | 2.99 - 5.43 | 1.56 - 7.78 | 4.02 | 2.5 - 6.18 | 13 | 13 | 0 | 5.64 | 5.48 | 2.66 - 8.62 | 0.86 - 21.61 | 4.58 | 2.18 - 5.65 | 0.3977 | 0.6866 | |
TREG+226-TIGIT- | Abs_Value | 13 | 13 | 0 | 2.65 | 2.38 | 1.36 - 3.94 | 0.1 - 8.35 | 1.52 | 0.93 - 3.87 | 13 | 13 | 0 | 2.11 | 1.55 | 1.26 - 2.95 | 0.36 - 6.14 | 1.57 | 1.19 - 2.92 | 0.4981 | 0.7192 | |
TREG+226-TIGIT+ | Abs_Value | 13 | 13 | 0 | 8.55 | 9.6 | 3.33 - 13.77 | 1.64 - 38.5 | 6.04 | 5.1 - 8.12 | 13 | 13 | 0 | 9.68 | 9.67 | 4.43 - 14.94 | 2.48 - 38.88 | 6.4 | 4.11 - 10.14 | 0.7663 | 0.8892 | |
TREG+226+ | Abs_Value | 13 | 13 | 0 | 23.33 | 17.35 | 13.9 - 32.76 | 5.38 - 73.34 | 18.84 | 18.45 - 20.72 | 13 | 13 | 0 | 24.82 | 15.9 | 16.17 - 33.46 | 11.37 - 58.24 | 16.66 | 14.9 - 27.08 | 0.8218 | 0.9094 | |
TREG+226+TIGIT- | Abs_Value | 13 | 13 | 0 | 3.58 | 1.73 | 2.64 - 4.51 | 0.75 - 6.7 | 3.71 | 2.55 - 4.11 | 13 | 13 | 0 | 3.56 | 2.26 | 2.33 - 4.79 | 0.51 - 7.21 | 3.12 | 1.9 - 5.7 | 0.9829 | 0.9889 | |
TREG+226+TIGIT+ | Abs_Value | 13 | 13 | 0 | 19.75 | 16.29 | 10.9 - 28.61 | 4.63 - 66.64 | 15.88 | 12.83 - 17.82 | 13 | 13 | 0 | 21.26 | 15.02 | 13.09 - 29.43 | 9.07 - 53.05 | 13.69 | 11.28 - 24.82 | 0.8088 | 0.9044 | |
TREG+39+ | Abs_Value | 13 | 13 | 0 | 25.41 | 26.51 | 11 - 39.82 | 2.29 - 106.13 | 19.11 | 14.33 - 23.39 | 13 | 13 | 0 | 23.29 | 14.76 | 15.27 - 31.32 | 3.34 - 61.46 | 21.21 | 14.48 - 30.08 | 0.8044 | 0.9015 | |
TREG+DR+ | Abs_Value | 13 | 13 | 0 | 22.98 | 20.31 | 11.94 - 34.02 | 5.52 - 82.63 | 17.99 | 13.55 - 21.67 | 13 | 13 | 0 | 26.36 | 22.63 | 14.06 - 38.66 | 9.15 - 87.97 | 19.48 | 11.7 - 26.27 | 0.6923 | 0.8514 | |
TREG+PD-1+ | Abs_Value | 13 | 13 | 0 | 17.32 | 19.33 | 6.81 - 27.83 | 3.42 - 77.43 | 12.22 | 7.39 - 18.37 | 13 | 13 | 0 | 16.03 | 11.14 | 9.98 - 22.09 | 4.48 - 48.13 | 13.81 | 11.21 - 15.23 | 0.8377 | 0.9139 | |
TREG+TIGIT+ | Abs_Value | 13 | 13 | 0 | 28.3 | 25.29 | 14.56 - 42.05 | 6.62 - 105.14 | 21.63 | 19.46 - 22.95 | 13 | 13 | 0 | 30.94 | 23.05 | 18.41 - 43.47 | 11.55 - 89.91 | 21.94 | 17.8 - 37.88 | 0.7833 | 0.8997 | |
+90 | 4_TFH | Abs_Value | 39 | 39 | 0 | 16.33 | 13.43 | 12.11 - 20.55 | 0 - 61.09 | 13.26 | 8.06 - 22.35 | 28 | 28 | 0 | 14.42 | 12.25 | 9.88 - 18.96 | 1.1 - 45.51 | 10.81 | 4.76 - 18.65 | 0.5483 | 0.7482 |
4_TH1 | Abs_Value | 39 | 39 | 0 | 35.1 | 96.74 | 4.74 - 65.47 | 0.16 - 608.2 | 10.47 | 5.84 - 24.35 | 28 | 28 | 0 | 17.24 | 24.14 | 8.3 - 26.19 | 0.03 - 113.81 | 9.26 | 4.29 - 17.68 | 0.2747 | 0.6781 | |
4_TH17 | Abs_Value | 39 | 39 | 0 | 13.84 | 8.71 | 11.11 - 16.57 | 0.02 - 34.84 | 12.75 | 6.74 - 18.73 | 28 | 28 | 0 | 13.49 | 9.77 | 9.87 - 17.11 | 0.86 - 40.22 | 11.94 | 6.64 - 20.16 | 0.8803 | 0.9395 | |
4_Th17TO1 | Abs_Value | 39 | 39 | 0 | 3.39 | 3.17 | 2.4 - 4.39 | 0.03 - 17.49 | 2.3 | 1.43 - 4.6 | 28 | 28 | 0 | 3.75 | 4.89 | 1.93 - 5.56 | 0.05 - 18.77 | 2.09 | 0.78 - 3.94 | 0.7375 | 0.8764 | |
4_TH2 | Abs_Value | 39 | 39 | 0 | 13.04 | 22.22 | 6.06 - 20.01 | 0.02 - 143.45 | 8.78 | 5.17 - 13.6 | 28 | 28 | 0 | 13.67 | 9.99 | 9.97 - 17.37 | 0.58 - 37.81 | 10.16 | 6.22 - 19.3 | 0.8754 | 0.9383 | |
4_TH22 | Abs_Value | 39 | 39 | 0 | 3.91 | 3.18 | 2.91 - 4.91 | 0 - 13.92 | 3.12 | 1.51 - 5.85 | 28 | 28 | 0 | 4.25 | 3.86 | 2.82 - 5.68 | 0.02 - 14.86 | 3.06 | 1.61 - 5.72 | 0.7032 | 0.8564 | |
4+ | Abs_Value | 39 | 39 | 0 | 70.84 | 76.56 | 46.81 - 94.87 | 0.01 - 430.92 | 59.43 | 20.66 - 92.9 | 28 | 28 | 0 | 83.71 | 46.4 | 66.52 - 100.89 | 1.65 - 194.52 | 81.98 | 48.2 - 121.66 | 0.3964 | 0.6866 | |
4+ (IM STAT) | Abs_Value | 39 | 39 | 0 | 65.93 | 72.58 | 43.14 - 88.71 | 0 - 397.77 | 47.44 | 19.37 - 82.94 | 28 | 28 | 0 | 74.78 | 44.66 | 58.24 - 91.32 | 2.77 - 186.76 | 77.26 | 37.17 - 96.8 | 0.5398 | 0.7475 | |
4+226+ | Abs_Value | 39 | 39 | 0 | 155.71 | 179.73 | 99.3 - 212.12 | 0.31 - 1046.46 | 128.08 | 68.58 - 160.33 | 28 | 28 | 0 | 132.45 | 73.4 | 105.26 - 159.64 | 16.89 - 269.89 | 131.07 | 76.06 - 166.98 | 0.4698 | 0.718 | |
4+39+ | Abs_Value | 39 | 39 | 0 | 39.48 | 31.48 | 29.6 - 49.36 | 0.07 - 135.08 | 37.22 | 19.19 - 54.81 | 28 | 28 | 0 | 40.21 | 33.36 | 27.86 - 52.57 | 0.49 - 110.79 | 34.79 | 9.36 - 63.23 | 0.9278 | 0.963 | |
4+DR+ | Abs_Value | 39 | 39 | 0 | 102.8 | 170.68 | 49.23 - 156.37 | 0.05 - 960.16 | 65.32 | 31.43 - 87.28 | 28 | 28 | 0 | 64.77 | 56.51 | 43.84 - 85.71 | 4.16 - 250.67 | 51.29 | 24.28 - 82.42 | 0.2011 | 0.6781 | |
4+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 48.64 | 34 | 37.97 - 59.31 | 0.03 - 131.28 | 34.59 | 25.53 - 75.58 | 28 | 28 | 0 | 55.29 | 44.79 | 38.69 - 71.88 | 6.67 - 166.24 | 41.71 | 22.29 - 76.75 | 0.5119 | 0.73 | |
4+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 8.16 | 24.25 | 0.55 - 15.77 | 0 - 154.31 | 3.78 | 1.76 - 6.59 | 28 | 28 | 0 | 4.87 | 3.39 | 3.61 - 6.12 | 0.25 - 12.65 | 3.76 | 2.29 - 7.19 | 0.4071 | 0.6902 | |
4+PD-1+ | Abs_Value | 39 | 39 | 0 | 108.13 | 148.15 | 61.64 - 154.63 | 0.33 - 789.05 | 77.82 | 46.08 - 97.71 | 28 | 28 | 0 | 82.56 | 62.59 | 59.37 - 105.74 | 7.01 - 256.14 | 70.45 | 36.32 - 110.92 | 0.3389 | 0.6781 | |
4+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 55.79 | 53.07 | 39.14 - 72.45 | 0.28 - 262.81 | 35.44 | 26.29 - 61.74 | 28 | 28 | 0 | 47.04 | 40.36 | 32.09 - 61.98 | 3.7 - 176.04 | 35.9 | 21.62 - 63.3 | 0.4459 | 0.7054 | |
4+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 52.34 | 100.95 | 20.66 - 84.03 | 0.05 - 526.23 | 28.49 | 18 - 44.4 | 28 | 28 | 0 | 35.52 | 29.85 | 24.47 - 46.58 | 3.31 - 119.05 | 23.88 | 15.59 - 49.99 | 0.3309 | 0.6781 | |
4+TIGIT+ | Abs_Value | 39 | 39 | 0 | 60.51 | 121.07 | 22.51 - 98.51 | 0.05 - 680.54 | 31.37 | 20.51 - 50.09 | 28 | 28 | 0 | 40.39 | 31.42 | 28.75 - 52.03 | 4.89 - 130.02 | 28.02 | 20.05 - 55.79 | 0.3264 | 0.6781 | |
4NV | Abs_Value | 39 | 39 | 0 | 17.03 | 15.12 | 12.28 - 21.78 | 0 - 55.9 | 12.73 | 6.44 - 21.38 | 28 | 28 | 0 | 28.77 | 26.38 | 19 - 38.55 | 3.15 - 110.75 | 18.27 | 8.39 - 39.7 | 0.0404 | 0.6781 | |
4NV(СТАР2) | Abs_Value | 39 | 39 | 0 | 15.95 | 15.14 | 11.2 - 20.7 | 0 - 54 | 10.42 | 6.42 - 18.05 | 28 | 28 | 0 | 26.63 | 24.08 | 17.71 - 35.55 | 4.36 - 99.11 | 18.69 | 7.91 - 35.34 | 0.0444 | 0.6781 | |
4NV_TH1 | Abs_Value | 39 | 39 | 0 | 1.27 | 1.37 | 0.84 - 1.7 | 0 - 6.02 | 0.92 | 0.31 - 1.7 | 28 | 28 | 0 | 1.99 | 2.02 | 1.24 - 2.74 | 0.01 - 7.62 | 1.39 | 0.42 - 2.94 | 0.1094 | 0.6781 | |
4NV_TH17 | Abs_Value | 39 | 39 | 0 | 0.59 | 0.58 | 0.41 - 0.77 | 0 - 2.9 | 0.41 | 0.18 - 0.81 | 28 | 28 | 0 | 0.92 | 0.76 | 0.64 - 1.2 | 0.12 - 3.24 | 0.68 | 0.45 - 1.19 | 0.0582 | 0.6781 | |
4NV_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.11 | 0.12 | 0.08 - 0.15 | 0 - 0.43 | 0.07 | 0.02 - 0.17 | 28 | 28 | 0 | 0.21 | 0.25 | 0.12 - 0.3 | 0.01 - 1.08 | 0.12 | 0.04 - 0.24 | 0.0737 | 0.6781 | |
4NV_TH2 | Abs_Value | 39 | 39 | 0 | 1.99 | 2.41 | 1.23 - 2.74 | 0 - 11.34 | 1.09 | 0.62 - 2.33 | 28 | 28 | 0 | 4.1 | 4.56 | 2.41 - 5.79 | 0.14 - 20.02 | 2.86 | 1.01 - 5.49 | 0.0312 | 0.6781 | |
4NV_TH22 | Abs_Value | 39 | 39 | 0 | 0.05 | 0.08 | 0.03 - 0.08 | 0 - 0.32 | 0.02 | 0.01 - 0.06 | 28 | 28 | 0 | 0.09 | 0.12 | 0.05 - 0.14 | 0 - 0.55 | 0.04 | 0.01 - 0.15 | 0.1106 | 0.6781 | |
4NV+226+ | Abs_Value | 39 | 39 | 0 | 13.74 | 13.09 | 9.63 - 17.84 | 0 - 43.3 | 9.21 | 6.11 - 15.8 | 28 | 28 | 0 | 23.13 | 21.19 | 15.28 - 30.98 | 3.48 - 85.04 | 16.11 | 7.06 - 29.98 | 0.044 | 0.6781 | |
4NV+39+ | Abs_Value | 39 | 39 | 0 | 0.7 | 0.89 | 0.42 - 0.98 | 0 - 3.98 | 0.4 | 0.1 - 0.87 | 28 | 28 | 0 | 0.98 | 0.98 | 0.61 - 1.34 | 0.01 - 4.69 | 0.75 | 0.48 - 1.13 | 0.2396 | 0.6781 | |
4NV+DR+ | Abs_Value | 39 | 39 | 0 | 1.96 | 3.25 | 0.94 - 2.98 | 0 - 17.28 | 0.83 | 0.41 - 1.75 | 28 | 28 | 0 | 1.75 | 1.95 | 1.03 - 2.47 | 0.25 - 10.14 | 1.16 | 0.7 - 1.82 | 0.7485 | 0.884 | |
4NV+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 14.19 | 14.36 | 9.69 - 18.7 | 0 - 47.46 | 9.27 | 4.44 - 17.37 | 28 | 28 | 0 | 24.61 | 23.7 | 15.84 - 33.39 | 2.32 - 98.02 | 16.98 | 6.11 - 33.64 | 0.0448 | 0.6781 | |
4NV+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.46 | 0.79 | 0.22 - 0.71 | 0 - 4.58 | 0.26 | 0.11 - 0.41 | 28 | 28 | 0 | 0.61 | 0.55 | 0.4 - 0.81 | 0.07 - 2.14 | 0.44 | 0.25 - 0.7 | 0.3928 | 0.6866 | |
4NV+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 0.87 | 1.14 | 0.51 - 1.23 | 0 - 4.56 | 0.35 | 0.23 - 0.96 | 28 | 28 | 0 | 0.93 | 0.76 | 0.65 - 1.21 | 0.1 - 3.04 | 0.72 | 0.34 - 1.24 | 0.7927 | 0.9 | |
4NV+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.42 | 0.56 | 0.25 - 0.6 | 0 - 2.84 | 0.19 | 0.08 - 0.57 | 28 | 28 | 0 | 0.48 | 0.35 | 0.35 - 0.61 | 0.05 - 1.27 | 0.4 | 0.23 - 0.62 | 0.5964 | 0.7763 | |
4NV+PD1+ | Abs_Value | 39 | 39 | 0 | 1.29 | 1.54 | 0.81 - 1.77 | 0 - 6.69 | 0.63 | 0.33 - 1.84 | 28 | 28 | 0 | 1.41 | 0.95 | 1.06 - 1.76 | 0.25 - 3.76 | 1.16 | 0.64 - 1.95 | 0.6939 | 0.8514 | |
4NV+TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.88 | 1.11 | 0.54 - 1.23 | 0 - 5.34 | 0.5 | 0.24 - 1.04 | 28 | 28 | 0 | 1.08 | 0.76 | 0.8 - 1.37 | 0.19 - 3.42 | 0.91 | 0.5 - 1.39 | 0.3839 | 0.6866 | |
4ЕМ | Abs_Value | 39 | 39 | 0 | 29.18 | 89.5 | 1.09 - 57.27 | 0.01 - 428.8 | 3.42 | 0.63 - 16.48 | 28 | 28 | 0 | 7.64 | 17.2 | 1.27 - 14.01 | 0 - 67.92 | 0.8 | 0.19 - 3.72 | 0.1502 | 0.6781 | |
4ЕМ_TH1 | Abs_Value | 39 | 39 | 0 | 11.29 | 43.51 | -2.37 - 24.94 | 0 - 267.92 | 1.06 | 0.16 - 3.75 | 28 | 28 | 0 | 1.94 | 5.86 | -0.23 - 4.11 | 0 - 30.53 | 0.2 | 0.03 - 0.92 | 0.1925 | 0.6781 | |
4ЕМ_TH17 | Abs_Value | 39 | 39 | 0 | 0.07 | 0.19 | 0.01 - 0.13 | 0 - 0.9 | 0.01 | 0 - 0.03 | 28 | 28 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.15 | 0 | 0 - 0.01 | 0.0572 | 0.6781 | |
4ЕМ_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.29 | 0.88 | 0.01 - 0.56 | 0 - 5.46 | 0.04 | 0.01 - 0.32 | 28 | 28 | 0 | 0.04 | 0.08 | 0.01 - 0.07 | 0 - 0.41 | 0.01 | 0 - 0.04 | 0.0894 | 0.6781 | |
4ЕМ_TH2 | Abs_Value | 39 | 39 | 0 | 3.8 | 21.09 | -2.81 - 10.42 | 0 - 131.99 | 0.08 | 0.02 - 0.43 | 28 | 28 | 0 | 0.3 | 0.62 | 0.07 - 0.53 | 0 - 2.67 | 0.03 | 0.01 - 0.2 | 0.3066 | 0.6781 | |
4ЕМ_TH22 | Abs_Value | 39 | 39 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.15 | 0 | 0 - 0 | 28 | 28 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.05 | 0 | 0 - 0 | 0.3268 | 0.6781 | |
4ЕМ+226+ | Abs_Value | 39 | 39 | 0 | 85.97 | 111.51 | 50.98 - 120.97 | 0.28 - 553.6 | 60.55 | 31.84 - 87.48 | 28 | 28 | 0 | 61.27 | 45.72 | 44.34 - 78.21 | 2.92 - 184.9 | 61.09 | 24.67 - 85.82 | 0.2184 | 0.6781 | |
4ЕМ+39+ | Abs_Value | 39 | 39 | 0 | 23.58 | 18.88 | 17.65 - 29.5 | 0.07 - 70.57 | 22.61 | 9.99 - 38 | 28 | 28 | 0 | 21.36 | 18.22 | 14.61 - 28.11 | 0.36 - 65.22 | 19.28 | 3.74 - 34.53 | 0.6308 | 0.7999 | |
4ЕМ+DR+ | Abs_Value | 39 | 39 | 0 | 64.34 | 103.15 | 31.97 - 96.71 | 0.05 - 497.18 | 41.66 | 22.69 - 54.93 | 28 | 28 | 0 | 39.41 | 37.3 | 25.59 - 53.22 | 1.61 - 158.94 | 31.55 | 12.09 - 55.55 | 0.1711 | 0.6781 | |
4ЕМ+PD1-TIGIT- | Abs_Value | 39 | 39 | 0 | 17.15 | 17.92 | 11.53 - 22.78 | 0.02 - 72.04 | 10.23 | 5.61 - 20.32 | 28 | 28 | 0 | 13.15 | 14.56 | 7.75 - 18.54 | 0.12 - 53.88 | 6.67 | 4.26 - 15.63 | 0.3174 | 0.6781 | |
4ЕМ+PD1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 3.48 | 10.15 | 0.29 - 6.66 | 0 - 64.16 | 1.27 | 0.67 - 2.64 | 28 | 28 | 0 | 1.74 | 1.51 | 1.18 - 2.3 | 0.03 - 5.22 | 1.22 | 0.61 - 2.92 | 0.2989 | 0.6781 | |
4ЕМ+PD1+ | Abs_Value | 39 | 39 | 0 | 68.62 | 97.13 | 38.13 - 99.1 | 0.31 - 488.16 | 42.29 | 29.92 - 67.94 | 28 | 28 | 0 | 49.55 | 43.2 | 33.55 - 65.55 | 2.85 - 169.81 | 41.27 | 18.21 - 65.64 | 0.2824 | 0.6781 | |
4ЕМ+PD1+TIGIT- | Abs_Value | 39 | 39 | 0 | 36.22 | 35.42 | 25.1 - 47.33 | 0.26 - 163.47 | 25.02 | 16.2 - 42.8 | 28 | 28 | 0 | 29.95 | 28.72 | 19.32 - 40.59 | 1.55 - 118.87 | 21.16 | 10.76 - 39.53 | 0.4278 | 0.7016 | |
4ЕМ+PD1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 32.4 | 66.32 | 11.58 - 53.22 | 0.05 - 343.46 | 16.95 | 9.28 - 23.66 | 28 | 28 | 0 | 19.6 | 19.73 | 12.29 - 26.9 | 1.3 - 92.73 | 14.3 | 6.25 - 25.74 | 0.2611 | 0.6781 | |
4ЕМ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 35.88 | 73.29 | 12.88 - 58.88 | 0.05 - 349.01 | 18.54 | 10.11 - 26.96 | 28 | 28 | 0 | 21.34 | 20.59 | 13.71 - 28.97 | 1.44 - 97.96 | 18.46 | 6.9 - 26.92 | 0.2457 | 0.6781 | |
4ЕМTM | Abs_Value | 39 | 39 | 0 | 89.25 | 112.7 | 53.88 - 124.62 | 0.33 - 560.51 | 61.41 | 33.6 - 92.27 | 28 | 28 | 0 | 64.44 | 48.25 | 46.57 - 82.31 | 3.5 - 201.17 | 63.48 | 25.56 - 91.84 | 0.225 | 0.6781 | |
4СМ | Abs_Value | 39 | 39 | 0 | 31.42 | 22.37 | 24.4 - 38.44 | 0 - 119.97 | 27.94 | 16.69 - 46.26 | 28 | 28 | 0 | 40.08 | 23.5 | 31.38 - 48.79 | 5.35 - 88.59 | 43.11 | 17.54 - 53.18 | 0.1344 | 0.6781 | |
4СМ(СТАР2) | Abs_Value | 39 | 39 | 0 | 30.02 | 22.79 | 22.87 - 37.17 | 0 - 133.51 | 26.43 | 16.63 - 38.84 | 28 | 28 | 0 | 32.97 | 19.84 | 25.62 - 40.32 | 1.94 - 67.99 | 34.65 | 16.28 - 44.77 | 0.5747 | 0.7601 | |
4СМ_TH1 | Abs_Value | 39 | 39 | 0 | 1.56 | 2.53 | 0.76 - 2.35 | 0 - 15.41 | 1.1 | 0.34 - 1.69 | 28 | 28 | 0 | 1.57 | 1.47 | 1.03 - 2.12 | 0 - 4.36 | 0.9 | 0.36 - 2.7 | 0.9785 | 0.9885 | |
4СМ_TH17 | Abs_Value | 39 | 39 | 0 | 5.03 | 3.89 | 3.81 - 6.25 | 0 - 15.87 | 4.24 | 1.91 - 7.32 | 28 | 28 | 0 | 6.77 | 5.73 | 4.65 - 8.89 | 0.22 - 20.07 | 4.4 | 2 - 10.07 | 0.17 | 0.6781 | |
4СМ_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.38 | 0.57 | 0.21 - 0.56 | 0 - 3.07 | 0.24 | 0.06 - 0.41 | 28 | 28 | 0 | 0.55 | 0.73 | 0.28 - 0.82 | 0.03 - 3.05 | 0.25 | 0.12 - 0.65 | 0.3224 | 0.6781 | |
4СМ_TH2 | Abs_Value | 39 | 39 | 0 | 3.18 | 2.55 | 2.38 - 3.98 | 0 - 11.68 | 2.61 | 1.48 - 4.55 | 28 | 28 | 0 | 5.02 | 4.33 | 3.42 - 6.63 | 0.29 - 18.6 | 4.09 | 1.54 - 8.19 | 0.0505 | 0.6781 | |
4СМ_TH22 | Abs_Value | 39 | 39 | 0 | 0.53 | 0.65 | 0.33 - 0.74 | 0 - 3.29 | 0.32 | 0.1 - 0.69 | 28 | 28 | 0 | 0.85 | 0.79 | 0.56 - 1.14 | 0.01 - 2.75 | 0.79 | 0.19 - 1.1 | 0.0902 | 0.6781 | |
4СМ+226+ | Abs_Value | 39 | 39 | 0 | 27.75 | 21.33 | 21.06 - 34.45 | 0 - 125.07 | 23.75 | 15.53 - 36.02 | 28 | 28 | 0 | 30.78 | 18.69 | 23.86 - 37.71 | 1.86 - 63.84 | 32.53 | 15.09 - 40.76 | 0.5396 | 0.7475 | |
4СМ+39+ | Abs_Value | 39 | 39 | 0 | 10.35 | 10.02 | 7.2 - 13.49 | 0 - 49.38 | 9.36 | 1.53 - 13.97 | 28 | 28 | 0 | 12.32 | 11.87 | 7.92 - 16.71 | 0.01 - 39.63 | 9.41 | 1.22 - 17.71 | 0.479 | 0.7185 | |
4СМ+DR+ | Abs_Value | 39 | 39 | 0 | 14.08 | 20.69 | 7.59 - 20.58 | 0 - 127.35 | 9.85 | 5.25 - 13.14 | 28 | 28 | 0 | 11.9 | 10.78 | 7.91 - 15.89 | 0.25 - 41.83 | 8.12 | 3.91 - 16.05 | 0.5771 | 0.7612 | |
4СМ+PD1-TIGIT- | Abs_Value | 39 | 39 | 0 | 9.47 | 6.39 | 7.46 - 11.47 | 0 - 23.26 | 7.52 | 5.37 - 13.64 | 28 | 28 | 0 | 11.96 | 10.31 | 8.14 - 15.78 | 0.12 - 41.2 | 8.6 | 4.25 - 18.41 | 0.264 | 0.6781 | |
4СМ+PD1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 1.44 | 2.08 | 0.78 - 2.09 | 0 - 12.64 | 0.77 | 0.45 - 2.01 | 28 | 28 | 0 | 1.41 | 1.22 | 0.96 - 1.86 | 0.01 - 4.72 | 1.1 | 0.6 - 1.79 | 0.9483 | 0.9711 | |
4СМ+PD1+ | Abs_Value | 39 | 39 | 0 | 19.12 | 18.7 | 13.25 - 24.99 | 0 - 111.86 | 16.09 | 9.77 - 23.86 | 28 | 28 | 0 | 19.6 | 14.8 | 14.12 - 25.08 | 0.46 - 61.96 | 17.76 | 10.26 - 23.57 | 0.9061 | 0.9546 | |
4СМ+PD1+TIGIT- | Abs_Value | 39 | 39 | 0 | 8.47 | 5.96 | 6.6 - 10.34 | 0 - 23.93 | 7.21 | 4.23 - 13.21 | 28 | 28 | 0 | 8.74 | 6.04 | 6.5 - 10.98 | 0.31 - 24.42 | 8.55 | 5.14 - 11.06 | 0.855 | 0.9205 | |
4СМ+PD1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 10.65 | 14.71 | 6.04 - 15.27 | 0 - 90.89 | 7.63 | 3.58 - 11.64 | 28 | 28 | 0 | 10.86 | 9.95 | 7.18 - 14.55 | 0.15 - 37.55 | 8.88 | 5.08 - 12.27 | 0.9441 | 0.9711 | |
4СМ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 12.09 | 16.62 | 6.87 - 17.31 | 0 - 103.53 | 9 | 4.03 - 13.68 | 28 | 28 | 0 | 12.28 | 10.32 | 8.45 - 16.1 | 0.27 - 38.44 | 10.69 | 5.63 - 14.57 | 0.9553 | 0.9711 | |
4ТM_TH1 | Abs_Value | 39 | 39 | 0 | 12.66 | 19.35 | 6.58 - 18.73 | 0.14 - 107.61 | 5.15 | 2.95 - 13.84 | 28 | 28 | 0 | 9.75 | 16.05 | 3.8 - 15.69 | 0.01 - 69.74 | 3.11 | 1.28 - 9.12 | 0.5047 | 0.7261 | |
4ТM_TH17 | Abs_Value | 39 | 39 | 0 | 7.59 | 5.69 | 5.8 - 9.37 | 0.02 - 20.47 | 5.91 | 3.82 - 10.49 | 28 | 28 | 0 | 5.4 | 4.24 | 3.83 - 6.97 | 0.07 - 17.72 | 4.87 | 2.86 - 7.51 | 0.0761 | 0.6781 | |
4ТM_Th17TO1 | Abs_Value | 39 | 39 | 0 | 2.19 | 1.71 | 1.65 - 2.72 | 0.03 - 6.88 | 1.88 | 0.98 - 3.01 | 28 | 28 | 0 | 2.64 | 3.74 | 1.26 - 4.02 | 0 - 13.42 | 1.26 | 0.4 - 2.99 | 0.5522 | 0.7482 | |
4ТM_TH2 | Abs_Value | 39 | 39 | 0 | 3.2 | 3.01 | 2.26 - 4.15 | 0.02 - 13.03 | 2.17 | 1.45 - 3.93 | 28 | 28 | 0 | 3.69 | 4.82 | 1.91 - 5.48 | 0.07 - 25.5 | 2.9 | 0.95 - 4.16 | 0.6371 | 0.8058 | |
4ТM_TH22 | Abs_Value | 39 | 39 | 0 | 3.03 | 2.8 | 2.15 - 3.91 | 0 - 11.23 | 1.9 | 1.07 - 4.73 | 28 | 28 | 0 | 2.99 | 3.07 | 1.85 - 4.12 | 0 - 11.35 | 2.21 | 0.77 - 4.02 | 0.9515 | 0.9711 | |
4ТREG | Abs_Value | 39 | 39 | 0 | 1.24 | 1.42 | 0.79 - 1.69 | 0 - 5.79 | 0.69 | 0.23 - 1.75 | 28 | 28 | 0 | 2.41 | 6.03 | 0.18 - 4.64 | 0.03 - 32.72 | 1.27 | 0.48 - 2.01 | 0.3225 | 0.6781 | |
4ТREG(СТАР2) | Abs_Value | 39 | 39 | 0 | 73 | 75.81 | 49.2 - 96.79 | 0.01 - 424.27 | 59.76 | 24.03 - 94.33 | 28 | 28 | 0 | 85.58 | 47.59 | 67.95 - 103.2 | 1.89 - 193.24 | 83.08 | 45.45 - 117.11 | 0.4082 | 0.6902 | |
4ТREG_TH1 | Abs_Value | 39 | 39 | 0 | 0.2 | 0.24 | 0.12 - 0.28 | 0 - 0.92 | 0.14 | 0.03 - 0.2 | 28 | 28 | 0 | 0.22 | 0.24 | 0.13 - 0.31 | 0 - 1 | 0.15 | 0.07 - 0.3 | 0.7316 | 0.8733 | |
4ТREG_TH17 | Abs_Value | 39 | 39 | 0 | 2.82 | 2.61 | 2 - 3.64 | 0.01 - 11.98 | 1.98 | 0.91 - 4.27 | 28 | 28 | 0 | 3.49 | 3.54 | 2.17 - 4.8 | 0.06 - 15.96 | 2.59 | 1.19 - 4.07 | 0.4005 | 0.6866 | |
4ТREG_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.07 | 0.1 | 0.04 - 0.1 | 0 - 0.44 | 0.04 | 0.01 - 0.08 | 28 | 28 | 0 | 0.1 | 0.14 | 0.05 - 0.15 | 0 - 0.47 | 0.04 | 0.02 - 0.1 | 0.3475 | 0.6781 | |
4ТREG_TH2 | Abs_Value | 39 | 39 | 0 | 1.54 | 1.37 | 1.11 - 1.97 | 0 - 5.88 | 1.46 | 0.53 - 2.34 | 28 | 28 | 0 | 2.23 | 2.84 | 1.18 - 3.28 | 0.22 - 14.5 | 1.3 | 0.74 - 3.06 | 0.2427 | 0.6781 | |
4ТREG_TH22 | Abs_Value | 39 | 39 | 0 | 1.69 | 2.05 | 1.05 - 2.33 | 0.01 - 11.04 | 1.01 | 0.55 - 2.04 | 28 | 28 | 0 | 1.82 | 1.85 | 1.14 - 2.51 | 0 - 8.31 | 1.47 | 0.4 - 2.49 | 0.7863 | 0.8997 | |
4ТЕ | Abs_Value | 39 | 39 | 0 | 11.59 | 46.78 | -3.09 - 26.27 | 0.01 - 293.46 | 0.64 | 0.2 - 5.63 | 28 | 28 | 0 | 2.37 | 3.82 | 0.96 - 3.78 | 0.03 - 14.73 | 0.88 | 0.24 - 2.04 | 0.2278 | 0.6781 | |
4ТЕ(СТАР2) | Abs_Value | 39 | 39 | 0 | 27.59 | 51.5 | 11.43 - 43.76 | 0.03 - 310.52 | 13.13 | 6.43 - 23.4 | 28 | 28 | 0 | 17.96 | 16.22 | 11.95 - 23.97 | 1.53 - 73.6 | 12.4 | 8.11 - 26.72 | 0.279 | 0.6781 | |
4ТЕ_TH1 | Abs_Value | 39 | 39 | 0 | 5.91 | 29.66 | -3.4 - 15.22 | 0 - 185.79 | 0.13 | 0.02 - 1.02 | 28 | 28 | 0 | 0.47 | 1.02 | 0.09 - 0.85 | 0 - 4.5 | 0.14 | 0.01 - 0.33 | 0.2599 | 0.6781 | |
4ТЕ_TH17 | Abs_Value | 39 | 39 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.17 | 0 | 0 - 0 | 28 | 28 | 0 | 0.01 | 0.02 | 0 - 0.01 | 0 - 0.07 | 0 | 0 - 0 | 0.4728 | 0.718 | |
4ТЕ_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.13 | 0.65 | -0.08 - 0.33 | 0 - 4.08 | 0.01 | 0 - 0.03 | 28 | 28 | 0 | 0.01 | 0.02 | 0 - 0.02 | 0 - 0.07 | 0 | 0 - 0.01 | 0.2706 | 0.6781 | |
4ТЕ_TH2 | Abs_Value | 39 | 39 | 0 | 0.42 | 1.36 | -0.01 - 0.84 | 0 - 6.25 | 0.01 | 0 - 0.12 | 28 | 28 | 0 | 0.08 | 0.13 | 0.04 - 0.13 | 0 - 0.51 | 0.02 | 0 - 0.12 | 0.1315 | 0.6781 | |
4ТЕ_TH22 | Abs_Value | 39 | 39 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.06 | 0 | 0 - 0.01 | 28 | 28 | 0 | 0 | 0.01 | 0 - 0.01 | 0 - 0.05 | 0 | 0 - 0 | 0.4354 | 0.7016 | |
4ТЕ+226+ | Abs_Value | 39 | 39 | 0 | 26.34 | 51.15 | 10.28 - 42.39 | 0.03 - 307.76 | 11.03 | 6.12 - 22.51 | 28 | 28 | 0 | 16.66 | 15.37 | 10.97 - 22.35 | 1.33 - 71.49 | 11.51 | 7.18 - 22.78 | 0.271 | 0.6781 | |
4ТЕ+39+ | Abs_Value | 39 | 39 | 0 | 4.33 | 3.99 | 3.08 - 5.59 | 0 - 17.63 | 3.24 | 0.79 - 6.09 | 28 | 28 | 0 | 5.45 | 6.64 | 2.99 - 7.91 | 0.05 - 29.5 | 3.18 | 1.51 - 6.83 | 0.4309 | 0.7016 | |
4ТЕ+DR+ | Abs_Value | 39 | 39 | 0 | 20.75 | 45.95 | 6.33 - 35.17 | 0 - 273.14 | 8.21 | 4.06 - 17.59 | 28 | 28 | 0 | 11.62 | 15.22 | 5.98 - 17.26 | 0.27 - 71.42 | 7.25 | 3.38 - 11.19 | 0.2534 | 0.6781 | |
4ТЕ+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 7.42 | 9.57 | 4.42 - 10.42 | 0 - 48.37 | 3.79 | 2.16 - 8.9 | 28 | 28 | 0 | 5.1 | 4.7 | 3.36 - 6.84 | 0.27 - 20.57 | 4.19 | 2.35 - 5.99 | 0.1945 | 0.6781 | |
4ТЕ+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 2.5 | 10.09 | -0.67 - 5.67 | 0 - 63.72 | 0.68 | 0.29 - 1.27 | 28 | 28 | 0 | 1.05 | 0.99 | 0.68 - 1.42 | 0.02 - 4.29 | 0.78 | 0.36 - 1.29 | 0.3773 | 0.6866 | |
4ТЕ+PD-1+ | Abs_Value | 39 | 39 | 0 | 17.67 | 35.09 | 6.66 - 28.68 | 0.02 - 198.43 | 7.84 | 3.82 - 16 | 28 | 28 | 0 | 11.81 | 14.43 | 6.47 - 17.16 | 0.53 - 65.87 | 7.14 | 3.15 - 12.28 | 0.3527 | 0.6781 | |
4ТЕ+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 9.85 | 14.26 | 5.38 - 14.33 | 0.02 - 68.31 | 3.85 | 2.12 - 11.01 | 28 | 28 | 0 | 7.28 | 9.7 | 3.69 - 10.88 | 0.31 - 45.47 | 3.94 | 1.99 - 7.31 | 0.3832 | 0.6866 | |
4ТЕ+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 7.82 | 22.22 | 0.84 - 14.79 | 0 - 130.12 | 2.71 | 1.56 - 4.95 | 28 | 28 | 0 | 4.53 | 5.52 | 2.49 - 6.58 | 0.23 - 21.97 | 2.11 | 1.41 - 5.09 | 0.3806 | 0.6866 | |
4ТЕ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 10.32 | 31.7 | 0.37 - 20.27 | 0 - 193.84 | 3.7 | 2.22 - 6.07 | 28 | 28 | 0 | 5.58 | 6.07 | 3.33 - 7.83 | 0.34 - 22.91 | 3.11 | 2.07 - 5.82 | 0.3679 | 0.6866 | |
4ТМ | Abs_Value | 39 | 39 | 0 | 68.73 | 44.83 | 54.66 - 82.8 | 0.29 - 206.37 | 59.16 | 36.36 - 89.43 | 28 | 28 | 0 | 60.2 | 43.52 | 44.08 - 76.32 | 2.7 - 156.95 | 59.02 | 21.18 - 93.81 | 0.4377 | 0.7016 | |
8+ | Abs_Value | 39 | 39 | 0 | 338.23 | 532.81 | 171.01 - 505.45 | 3.6 - 2131.88 | 94.25 | 33.79 - 338.12 | 28 | 28 | 0 | 163.88 | 420.4 | 8.16 - 319.59 | 0.65 - 2174.4 | 32.02 | 7.98 - 107.38 | 0.1397 | 0.6781 | |
8+ (IM STAT) | Abs_Value | 39 | 39 | 0 | 367.88 | 552.6 | 194.44 - 541.31 | 3.93 - 2176.1 | 99.73 | 39.92 - 499.23 | 28 | 28 | 0 | 190.71 | 457.37 | 21.29 - 360.12 | 0.71 - 2351.17 | 40.68 | 13.82 - 116.25 | 0.1569 | 0.6781 | |
8+226+ | Abs_Value | 39 | 39 | 0 | 470.53 | 618.71 | 276.35 - 664.71 | 19.73 - 2309.79 | 182.21 | 83.91 - 662.23 | 28 | 28 | 0 | 254.15 | 484.55 | 74.67 - 433.63 | 7.76 - 2484.23 | 93.15 | 40.59 - 227.28 | 0.1136 | 0.6781 | |
8+39+ | Abs_Value | 39 | 39 | 0 | 50.88 | 78.12 | 26.36 - 75.39 | 0.09 - 418.95 | 23.41 | 8.89 - 61.49 | 28 | 28 | 0 | 47.44 | 107.14 | 7.75 - 87.13 | 0.2 - 562.33 | 12.38 | 3.76 - 49.88 | 0.8858 | 0.9413 | |
8+DR+ | Abs_Value | 39 | 39 | 0 | 367.32 | 527.47 | 201.78 - 532.87 | 4.94 - 2168.46 | 142.83 | 62.61 - 414.98 | 28 | 28 | 0 | 216.12 | 474.09 | 40.51 - 391.73 | 2.26 - 2431.19 | 63.22 | 19.15 - 162.93 | 0.2241 | 0.6781 | |
8+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 135.49 | 198.3 | 73.25 - 197.72 | 5.63 - 815.7 | 39.97 | 17.51 - 139.58 | 28 | 28 | 0 | 76.66 | 134.27 | 26.93 - 126.39 | 1.36 - 704.51 | 40.59 | 10.93 - 84.58 | 0.1526 | 0.6781 | |
8+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 144.2 | 244.69 | 67.4 - 221 | 1.37 - 1271.22 | 31.04 | 10.46 - 209.95 | 28 | 28 | 0 | 65.97 | 141.78 | 13.46 - 118.49 | 1 - 719.74 | 15.57 | 7.8 - 62.55 | 0.1044 | 0.6781 | |
8+PD-1+ | Abs_Value | 39 | 39 | 0 | 217.19 | 328.31 | 114.15 - 320.23 | 7.78 - 1736.81 | 95 | 38.06 - 229.28 | 28 | 28 | 0 | 133.94 | 258.59 | 38.15 - 229.72 | 1.8 - 1201.16 | 35.47 | 16.3 - 80.32 | 0.2504 | 0.6781 | |
8+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 71.54 | 104.23 | 38.83 - 104.25 | 1.45 - 448.19 | 26.52 | 4.16 - 106.41 | 28 | 28 | 0 | 41.87 | 87.52 | 9.45 - 74.29 | 0.7 - 428.96 | 12.39 | 3.78 - 32.22 | 0.2113 | 0.6781 | |
8+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 145.65 | 238.86 | 70.69 - 220.62 | 5.05 - 1288.62 | 68.95 | 21.04 - 122.68 | 28 | 28 | 0 | 92.07 | 178.77 | 25.85 - 158.28 | 0.99 - 772.2 | 19.64 | 11.2 - 49.28 | 0.2976 | 0.6781 | |
8+TIGIT+ | Abs_Value | 39 | 39 | 0 | 289.85 | 431.67 | 154.37 - 425.33 | 6.42 - 1840.75 | 94.56 | 43.22 - 313.01 | 28 | 28 | 0 | 158.04 | 314.31 | 41.62 - 274.46 | 1.99 - 1491.94 | 43.96 | 19.14 - 109.1 | 0.1529 | 0.6781 | |
8EMTM | Abs_Value | 39 | 39 | 0 | 77.74 | 115.56 | 41.47 - 114 | 2.95 - 582.56 | 29.11 | 9.7 - 91.47 | 28 | 28 | 0 | 70.04 | 204.35 | -5.65 - 145.73 | 0.4 - 1077.88 | 11.45 | 3.34 - 45.52 | 0.8582 | 0.9219 | |
8EMTM+226+ | Abs_Value | 39 | 39 | 0 | 72.96 | 112.94 | 37.51 - 108.41 | 2.29 - 577.84 | 28.32 | 7.48 - 83.22 | 28 | 28 | 0 | 64.24 | 192.62 | -7.11 - 135.59 | 0.36 - 1020.79 | 10.3 | 2.38 - 43.16 | 0.8312 | 0.91 | |
8EMTM+39+ | Abs_Value | 39 | 39 | 0 | 14.47 | 23.42 | 7.12 - 21.82 | 0.04 - 99.93 | 4.62 | 1.73 - 15.46 | 28 | 28 | 0 | 15.07 | 51.88 | -4.14 - 34.29 | 0.03 - 277.35 | 1.72 | 0.75 - 9.77 | 0.9544 | 0.9711 | |
8EMTM+DR+ | Abs_Value | 39 | 39 | 0 | 64.68 | 100.49 | 33.15 - 96.22 | 1.79 - 474.38 | 25.43 | 8.16 - 71.87 | 28 | 28 | 0 | 62.31 | 194.49 | -9.73 - 134.35 | 0.28 - 1026.67 | 6.98 | 1.25 - 30.94 | 0.9532 | 0.9711 | |
8EMTM+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 16.56 | 28.57 | 7.59 - 25.52 | 0.1 - 131.33 | 4.96 | 1.16 - 19.06 | 28 | 28 | 0 | 14.71 | 44.65 | -1.83 - 31.25 | 0.1 - 237.98 | 2.42 | 0.29 - 9.52 | 0.8481 | 0.9196 | |
8EMTM+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 18.89 | 47.24 | 4.06 - 33.71 | 0.12 - 275.2 | 4.85 | 0.88 - 12.82 | 28 | 28 | 0 | 12.87 | 39.42 | -1.74 - 27.47 | 0.04 - 206 | 0.93 | 0.23 - 7.56 | 0.5727 | 0.7599 | |
8EMTM+PD-1+ | Abs_Value | 39 | 39 | 0 | 42.29 | 57.22 | 24.33 - 60.25 | 2.21 - 240.61 | 17.22 | 6.99 - 48.08 | 28 | 28 | 0 | 42.46 | 121.77 | -2.64 - 87.57 | 0.27 - 633.9 | 6.11 | 1.59 - 25.15 | 0.9945 | 0.9959 | |
8EMTM+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 13 | 16.61 | 7.78 - 18.21 | 0.2 - 74.77 | 5.86 | 1.15 - 19.09 | 28 | 28 | 0 | 13.87 | 44.21 | -2.5 - 30.25 | 0.08 - 235.25 | 2.36 | 0.47 - 7.78 | 0.9209 | 0.9599 | |
8EMTM+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 29.3 | 44.1 | 15.46 - 43.14 | 0.71 - 188.94 | 11.73 | 3.71 - 27.49 | 28 | 28 | 0 | 28.59 | 79.29 | -0.78 - 57.96 | 0.12 - 398.65 | 3.64 | 1.15 - 13.56 | 0.9662 | 0.9801 | |
8EMTM+TIGIT+ | Abs_Value | 39 | 39 | 0 | 48.18 | 86.13 | 21.15 - 75.22 | 0.83 - 464.14 | 17.79 | 5.39 - 42.69 | 28 | 28 | 0 | 41.46 | 118.34 | -2.38 - 85.29 | 0.16 - 604.65 | 4.85 | 1.71 - 21.19 | 0.799 | 0.9 | |
8NV | Abs_Value | 39 | 39 | 0 | 7.64 | 9.28 | 4.73 - 10.56 | 0.02 - 46.45 | 5.08 | 1.98 - 8.98 | 28 | 28 | 0 | 11.62 | 11.65 | 7.31 - 15.94 | 0.67 - 55.43 | 7.91 | 5.17 - 17.08 | 0.1405 | 0.6781 | |
8NV(СТАР2) | Abs_Value | 39 | 39 | 0 | 9.6 | 11.35 | 6.04 - 13.16 | 0.03 - 49.35 | 5.19 | 2.26 - 10.73 | 28 | 28 | 0 | 11.25 | 10.66 | 7.3 - 15.19 | 1.05 - 48.26 | 6.76 | 4.77 - 14.25 | 0.5468 | 0.7482 | |
8NV+226+ | Abs_Value | 39 | 39 | 0 | 8.68 | 10.74 | 5.31 - 12.05 | 0.03 - 49.26 | 4.68 | 1.99 - 10.06 | 28 | 28 | 0 | 9.91 | 9.3 | 6.47 - 13.36 | 0.95 - 40.2 | 5.96 | 4.28 - 12.51 | 0.6174 | 0.7904 | |
8NV+39+ | Abs_Value | 39 | 39 | 0 | 0.6 | 0.97 | 0.29 - 0.9 | 0 - 5.17 | 0.3 | 0.06 - 0.64 | 28 | 28 | 0 | 0.67 | 0.81 | 0.36 - 0.97 | 0.01 - 3.73 | 0.44 | 0.13 - 0.8 | 0.7558 | 0.884 | |
8NV+DR+ | Abs_Value | 39 | 39 | 0 | 2.56 | 4.43 | 1.17 - 3.96 | 0.01 - 16.54 | 0.66 | 0.3 - 1.9 | 28 | 28 | 0 | 1.37 | 2.02 | 0.62 - 2.12 | 0.03 - 9.92 | 0.6 | 0.44 - 1.22 | 0.1426 | 0.6781 | |
8NV+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 7.04 | 9.42 | 4.09 - 10 | 0 - 43.98 | 3.81 | 1.03 - 8.78 | 28 | 28 | 0 | 9.61 | 10.56 | 5.7 - 13.52 | 0.23 - 47.12 | 5.74 | 3.06 - 12.31 | 0.3088 | 0.6781 | |
8NV+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 1.11 | 1.92 | 0.51 - 1.72 | 0 - 9.21 | 0.49 | 0.22 - 0.85 | 28 | 28 | 0 | 0.73 | 0.83 | 0.42 - 1.03 | 0.05 - 3.77 | 0.46 | 0.23 - 0.72 | 0.2655 | 0.6781 | |
8NV+PD-1+ | Abs_Value | 39 | 39 | 0 | 1.45 | 2.12 | 0.78 - 2.11 | 0.02 - 10 | 0.52 | 0.2 - 1.5 | 28 | 28 | 0 | 0.91 | 1.11 | 0.5 - 1.32 | 0.05 - 3.96 | 0.44 | 0.23 - 1.06 | 0.1836 | 0.6781 | |
8NV+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 0.5 | 0.92 | 0.21 - 0.79 | 0 - 4.91 | 0.15 | 0.03 - 0.5 | 28 | 28 | 0 | 0.31 | 0.36 | 0.18 - 0.45 | 0 - 1.26 | 0.2 | 0.08 - 0.4 | 0.2527 | 0.6781 | |
8NV+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.95 | 1.35 | 0.52 - 1.37 | 0.01 - 5.16 | 0.39 | 0.15 - 1.12 | 28 | 28 | 0 | 0.6 | 0.89 | 0.27 - 0.92 | 0.04 - 3.31 | 0.25 | 0.17 - 0.38 | 0.2056 | 0.6781 | |
8NV+TIGIT+ | Abs_Value | 39 | 39 | 0 | 2.06 | 3.05 | 1.1 - 3.02 | 0.01 - 12.72 | 0.88 | 0.45 - 2.26 | 28 | 28 | 0 | 1.32 | 1.63 | 0.72 - 1.93 | 0.11 - 6.55 | 0.64 | 0.46 - 1.05 | 0.2063 | 0.6781 | |
8TREG | Abs_Value | 39 | 39 | 0 | 334.51 | 529.5 | 168.33 - 500.7 | 3.32 - 2109.36 | 93.76 | 33.11 - 326.8 | 28 | 28 | 0 | 166.61 | 430.63 | 7.1 - 326.11 | 0.67 - 2227.15 | 31.77 | 8.02 - 102.77 | 0.158 | 0.6781 | |
8ЕМ | Abs_Value | 39 | 39 | 0 | 79.03 | 128.38 | 38.73 - 119.32 | 0.46 - 668.2 | 28.95 | 7.36 - 99.94 | 28 | 28 | 0 | 67.68 | 206.05 | -8.64 - 144 | 0.11 - 1084.06 | 7.04 | 1.01 - 34.8 | 0.7979 | 0.9 | |
8СМ | Abs_Value | 39 | 39 | 0 | 2.88 | 6.14 | 0.95 - 4.81 | 0.01 - 37.25 | 0.94 | 0.56 - 2.43 | 28 | 28 | 0 | 5.32 | 12.63 | 0.64 - 9.99 | 0.08 - 67.57 | 2.36 | 0.34 - 5.01 | 0.351 | 0.6781 | |
8СМ(СТАР2) | Abs_Value | 39 | 39 | 0 | 6 | 19.68 | -0.18 - 12.17 | 0.02 - 118.92 | 1.16 | 0.72 - 3.09 | 28 | 28 | 0 | 3.83 | 5.57 | 1.77 - 5.9 | 0.02 - 19.92 | 1.88 | 0.27 - 4.27 | 0.5181 | 0.7367 | |
8СМ+226+ | Abs_Value | 39 | 39 | 0 | 5.61 | 19.33 | -0.46 - 11.67 | 0.02 - 118.25 | 1.08 | 0.6 - 2.93 | 28 | 28 | 0 | 3.33 | 4.75 | 1.57 - 5.09 | 0.02 - 16.84 | 1.68 | 0.22 - 3.34 | 0.483 | 0.7191 | |
8СМ+39+ | Abs_Value | 39 | 39 | 0 | 0.93 | 1.62 | 0.43 - 1.44 | 0 - 9.34 | 0.47 | 0.18 - 0.76 | 28 | 28 | 0 | 1.27 | 1.93 | 0.55 - 1.98 | 0 - 6.95 | 0.2 | 0.07 - 1.77 | 0.4626 | 0.7142 | |
8СМ+DR+ | Abs_Value | 39 | 39 | 0 | 5.16 | 17.97 | -0.48 - 10.8 | 0.01 - 107.27 | 0.96 | 0.51 - 2.09 | 28 | 28 | 0 | 2.81 | 5.22 | 0.87 - 4.74 | 0.01 - 19.49 | 0.69 | 0.13 - 1.93 | 0.4428 | 0.7032 | |
8СМ+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 1.23 | 2.88 | 0.32 - 2.13 | 0 - 15.65 | 0.25 | 0.11 - 0.88 | 28 | 28 | 0 | 1.12 | 1.58 | 0.54 - 1.71 | 0 - 5.79 | 0.49 | 0.11 - 1.24 | 0.8486 | 0.9196 | |
8СМ+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 2.1 | 9.31 | -0.83 - 5.02 | 0 - 58.16 | 0.2 | 0.1 - 0.58 | 28 | 28 | 0 | 0.69 | 1.18 | 0.25 - 1.12 | 0 - 5.17 | 0.2 | 0.05 - 0.61 | 0.3555 | 0.6781 | |
8СМ+PD-1+ | Abs_Value | 39 | 39 | 0 | 2.67 | 7.9 | 0.2 - 5.15 | 0.02 - 45.11 | 0.74 | 0.28 - 1.51 | 28 | 28 | 0 | 2.03 | 3.93 | 0.57 - 3.48 | 0.01 - 15.63 | 0.52 | 0.1 - 1.43 | 0.6598 | 0.8271 | |
8СМ+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 0.68 | 1.95 | 0.07 - 1.29 | 0 - 9.81 | 0.15 | 0.03 - 0.35 | 28 | 28 | 0 | 0.49 | 1 | 0.12 - 0.86 | 0.01 - 4.45 | 0.11 | 0.04 - 0.38 | 0.6059 | 0.7822 | |
8СМ+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 1.99 | 6.19 | 0.05 - 3.94 | 0.01 - 37.26 | 0.62 | 0.21 - 1.18 | 28 | 28 | 0 | 1.53 | 2.99 | 0.43 - 2.64 | 0 - 11.18 | 0.39 | 0.06 - 1.08 | 0.6889 | 0.8514 | |
8СМ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 4.09 | 15.41 | -0.75 - 8.93 | 0.01 - 95.42 | 0.8 | 0.34 - 1.64 | 28 | 28 | 0 | 2.22 | 3.86 | 0.79 - 3.65 | 0 - 12.71 | 0.7 | 0.13 - 2.13 | 0.4714 | 0.718 | |
8ТЕ | Abs_Value | 39 | 39 | 0 | 340.55 | 488.28 | 187.3 - 493.79 | 4.38 - 1891.65 | 72.89 | 27.04 - 523.74 | 28 | 28 | 0 | 135.07 | 228.34 | 50.49 - 219.65 | 0.46 - 1033.99 | 42.13 | 12.61 - 131.19 | 0.0251 | 0.6781 | |
8ТЕ(СТАР2) | Abs_Value | 39 | 39 | 0 | 399.82 | 532.76 | 232.61 - 567.03 | 7.72 - 2117.62 | 121.61 | 53.59 - 623.55 | 28 | 28 | 0 | 190.71 | 317.08 | 73.26 - 308.16 | 2.04 - 1520.64 | 74.98 | 26.84 - 165.62 | 0.0492 | 0.6781 | |
8ТЕ+226+ | Abs_Value | 39 | 39 | 0 | 380.04 | 511.32 | 219.56 - 540.51 | 6.99 - 1998.95 | 102.32 | 50.26 - 599.53 | 28 | 28 | 0 | 176.1 | 299.7 | 65.09 - 287.11 | 1.84 - 1441.91 | 61.81 | 24.47 - 147.36 | 0.0447 | 0.6781 | |
8ТЕ+39+ | Abs_Value | 39 | 39 | 0 | 34.3 | 57.18 | 16.35 - 52.25 | 0.05 - 321.3 | 13.22 | 3.65 - 43.95 | 28 | 28 | 0 | 30.36 | 56.92 | 9.27 - 51.44 | 0.07 - 278.04 | 7.6 | 2.95 - 34.51 | 0.781 | 0.8997 | |
8ТЕ+DR+ | Abs_Value | 39 | 39 | 0 | 291.49 | 426.01 | 157.79 - 425.2 | 2.61 - 1916.64 | 93.22 | 40.64 - 361.39 | 28 | 28 | 0 | 149.34 | 282.01 | 44.88 - 253.8 | 1.18 - 1379.51 | 39.48 | 15.08 - 122 | 0.1054 | 0.6781 | |
8ТЕ+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 109.69 | 170.26 | 56.25 - 163.13 | 2.07 - 692.88 | 26.6 | 9.18 - 117.4 | 28 | 28 | 0 | 50.89 | 89.3 | 17.81 - 83.97 | 0.56 - 459.76 | 20.6 | 5.05 - 62.44 | 0.0716 | 0.6781 | |
8ТЕ+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 121.05 | 193.14 | 60.43 - 181.66 | 0.99 - 921.44 | 24.4 | 8.44 - 190.13 | 28 | 28 | 0 | 51.55 | 101.85 | 13.82 - 89.27 | 0.45 - 504.62 | 14.1 | 4.74 - 55.63 | 0.0612 | 0.6781 | |
8ТЕ+PD-1+ | Abs_Value | 39 | 39 | 0 | 169.08 | 280.68 | 80.99 - 257.17 | 3.69 - 1526.37 | 67.37 | 26.03 - 170.51 | 28 | 28 | 0 | 88.27 | 149.38 | 32.94 - 143.6 | 1.03 - 556.25 | 29.97 | 12.58 - 69.83 | 0.1331 | 0.6781 | |
8ТЕ+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 56.8 | 90.76 | 28.31 - 85.28 | 0.82 - 403.46 | 18.56 | 2.45 - 72.41 | 28 | 28 | 0 | 27.18 | 48.92 | 9.06 - 45.3 | 0.47 - 190.87 | 7.59 | 2.07 - 25.75 | 0.0906 | 0.6781 | |
8ТЕ+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 112.28 | 201.35 | 49.09 - 175.48 | 2.85 - 1122.91 | 47.52 | 13.89 - 97.11 | 28 | 28 | 0 | 61.09 | 106.19 | 21.76 - 100.43 | 0.56 - 365.38 | 14.54 | 8.69 - 41.59 | 0.1827 | 0.6781 | |
8ТЕ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 233.33 | 346.67 | 124.53 - 342.13 | 3.84 - 1498.44 | 77.37 | 26.2 - 269.88 | 28 | 28 | 0 | 112.64 | 198.57 | 39.09 - 186.19 | 1.01 - 870 | 29.7 | 14.87 - 94.69 | 0.0765 | 0.6781 | |
8ТМ | Abs_Value | 39 | 39 | 0 | 20.92 | 28 | 12.13 - 29.7 | 0.43 - 149.26 | 12.18 | 4.59 - 22.53 | 28 | 28 | 0 | 20.26 | 37.21 | 6.47 - 34.04 | 0.34 - 179.51 | 5.25 | 1.36 - 17.61 | 0.9375 | 0.9711 | |
TREG_CM | Abs_Value | 39 | 39 | 0 | 0.81 | 0.88 | 0.54 - 1.09 | 0 - 4.33 | 0.5 | 0.26 - 1.08 | 28 | 28 | 0 | 1.48 | 2.72 | 0.47 - 2.49 | 0.02 - 14.66 | 0.92 | 0.32 - 1.56 | 0.2223 | 0.6781 | |
TREG_EMTM | Abs_Value | 39 | 39 | 0 | 8.82 | 8.27 | 6.22 - 11.41 | 0.05 - 40.11 | 7.21 | 2.95 - 12.43 | 28 | 28 | 0 | 11.9 | 17.5 | 5.42 - 18.38 | 0.05 - 93.26 | 6.51 | 3.01 - 13.22 | 0.3923 | 0.6866 | |
TREG_NV | Abs_Value | 39 | 39 | 0 | 0.93 | 0.89 | 0.65 - 1.21 | 0 - 3.03 | 0.71 | 0.21 - 1.47 | 28 | 28 | 0 | 1.21 | 0.82 | 0.91 - 1.52 | 0.01 - 3.4 | 1.13 | 0.63 - 1.75 | 0.1786 | 0.6781 | |
TREG_TE | Abs_Value | 39 | 39 | 0 | 2.37 | 1.78 | 1.81 - 2.93 | 0 - 6.11 | 2.06 | 1.15 - 3.5 | 28 | 28 | 0 | 3.04 | 2.65 | 2.06 - 4.02 | 0.19 - 8.97 | 2.17 | 0.97 - 4.09 | 0.2505 | 0.6781 | |
TREG+226-TIGIT- | Abs_Value | 39 | 39 | 0 | 0.85 | 0.78 | 0.61 - 1.1 | 0 - 2.66 | 0.63 | 0.17 - 1.39 | 28 | 28 | 0 | 0.88 | 0.74 | 0.61 - 1.15 | 0.04 - 3.18 | 0.69 | 0.34 - 1.18 | 0.8825 | 0.9398 | |
TREG+226-TIGIT+ | Abs_Value | 39 | 39 | 0 | 3.39 | 3.18 | 2.39 - 4.39 | 0.01 - 13.35 | 2.67 | 0.95 - 4.88 | 28 | 28 | 0 | 4.62 | 7.57 | 1.82 - 7.43 | 0.22 - 40.78 | 2.82 | 1.46 - 4.13 | 0.4216 | 0.6984 | |
TREG+226+ | Abs_Value | 39 | 39 | 0 | 8.82 | 7.4 | 6.49 - 11.14 | 0.04 - 38.28 | 9.02 | 3.48 - 11.72 | 28 | 28 | 0 | 12.15 | 14.13 | 6.92 - 17.38 | 0.85 - 72.45 | 7.91 | 3.79 - 14.59 | 0.2615 | 0.6781 | |
TREG+226+TIGIT- | Abs_Value | 39 | 39 | 0 | 1.36 | 1.22 | 0.98 - 1.75 | 0.01 - 4.82 | 0.92 | 0.52 - 1.82 | 28 | 28 | 0 | 1.67 | 1.7 | 1.04 - 2.3 | 0.06 - 7.96 | 1.15 | 0.6 - 1.92 | 0.413 | 0.6959 | |
TREG+226+TIGIT+ | Abs_Value | 39 | 39 | 0 | 7.46 | 6.55 | 5.4 - 9.51 | 0.02 - 33.46 | 6.06 | 2.41 - 10.44 | 28 | 28 | 0 | 10.48 | 13.51 | 5.47 - 15.48 | 0.25 - 70.7 | 6.52 | 3.05 - 13.06 | 0.2811 | 0.6781 | |
TREG+39+ | Abs_Value | 39 | 39 | 0 | 9.7 | 9.56 | 6.7 - 12.7 | 0.03 - 45.27 | 6.69 | 3.41 - 11.8 | 28 | 28 | 0 | 13.81 | 20.79 | 6.11 - 21.52 | 0.18 - 111.4 | 8.3 | 3.67 - 15.91 | 0.336 | 0.6781 | |
TREG+DR+ | Abs_Value | 39 | 39 | 0 | 9.7 | 8.49 | 7.03 - 12.36 | 0.02 - 39.81 | 8.49 | 3.47 - 13.01 | 28 | 28 | 0 | 13.29 | 19.64 | 6.01 - 20.56 | 0.59 - 105.25 | 8.1 | 3.56 - 14.05 | 0.3701 | 0.6866 | |
TREG+PD-1+ | Abs_Value | 39 | 39 | 0 | 4.45 | 3.85 | 3.25 - 5.66 | 0.04 - 18.35 | 3.67 | 1.4 - 6.2 | 28 | 28 | 0 | 7.17 | 13.16 | 2.29 - 12.04 | 0.13 - 69.61 | 3.88 | 1.6 - 7.43 | 0.2978 | 0.6781 | |
TREG+TIGIT+ | Abs_Value | 39 | 39 | 0 | 10.84 | 9.27 | 7.93 - 13.75 | 0.03 - 42.48 | 10.53 | 3.55 - 14.81 | 28 | 28 | 0 | 15.1 | 20.74 | 7.42 - 22.78 | 0.47 - 111.49 | 9.01 | 5.36 - 17.63 | 0.3169 | 0.6781 | |
ДЕНЬ ХРРТПХ | 4_TFH | Abs_Value | 25 | 25 | 0 | 46.78 | 39.66 | 31.24 - 62.33 | 3.66 - 168.34 | 34.25 | 19.83 - 64.77 | Н/П* | Н/П* | |||||||||
4_TH1 | Abs_Value | 25 | 25 | 0 | 28.17 | 17.06 | 21.49 - 34.86 | 2.66 - 65.39 | 29.97 | 13.25 - 43.17 | Н/П* | Н/П* | ||||||||||
4_TH17 | Abs_Value | 25 | 25 | 0 | 23.29 | 13.52 | 17.99 - 28.59 | 6.68 - 64.57 | 22.22 | 12.65 - 29.78 | Н/П* | Н/П* | ||||||||||
4_Th17TO1 | Abs_Value | 25 | 25 | 0 | 6.06 | 5.4 | 3.95 - 8.18 | 0.56 - 23.85 | 3.82 | 2.86 - 8.1 | Н/П* | Н/П* | ||||||||||
4_TH2 | Abs_Value | 25 | 25 | 0 | 24.18 | 26.58 | 13.76 - 34.6 | 3.39 - 132.22 | 18.42 | 6.59 - 29.27 | Н/П* | Н/П* | ||||||||||
4_TH22 | Abs_Value | 25 | 25 | 0 | 9.62 | 7.61 | 6.64 - 12.61 | 0.26 - 32.21 | 8.69 | 4.42 - 13.49 | Н/П* | Н/П* | ||||||||||
4+ | Abs_Value | 25 | 25 | 0 | 123.28 | 57.09 | 100.9 - 145.65 | 16.38 - 237.04 | 115.81 | 79.15 - 170.15 | Н/П* | Н/П* | ||||||||||
4+ (IM STAT) | Abs_Value | 25 | 25 | 0 | 97.67 | 44.6 | 80.19 - 115.15 | 13.95 - 188.96 | 87.06 | 67.78 - 126.32 | Н/П* | Н/П* | ||||||||||
4+226+ | Abs_Value | 25 | 25 | 0 | 284.34 | 122.79 | 236.2 - 332.47 | 44.53 - 608.12 | 278.03 | 201.64 - 345.8 | Н/П* | Н/П* | ||||||||||
4+39+ | Abs_Value | 25 | 25 | 0 | 85.6 | 65.58 | 59.89 - 111.31 | 1.02 - 286.69 | 76.43 | 53.19 - 108.3 | Н/П* | Н/П* | ||||||||||
4+DR+ | Abs_Value | 25 | 25 | 0 | 133.94 | 87.87 | 99.5 - 168.39 | 24.34 - 400.84 | 100.49 | 65.24 - 183.02 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 109.61 | 70.62 | 81.92 - 137.29 | 11.55 - 243.96 | 96.09 | 49.56 - 150.68 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 11.95 | 10.29 | 7.91 - 15.98 | 0.92 - 41.1 | 7.95 | 3.98 - 17.77 | Н/П* | Н/П* | ||||||||||
4+PD-1+ | Abs_Value | 25 | 25 | 0 | 182.38 | 99.2 | 143.5 - 221.27 | 33.38 - 484.17 | 145.59 | 109.23 - 237.38 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 100.64 | 63.31 | 75.83 - 125.46 | 20.2 - 286.07 | 76.64 | 62.96 - 141.45 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 81.74 | 43.96 | 64.51 - 98.97 | 13.19 - 198.1 | 79.59 | 47.71 - 110.6 | Н/П* | Н/П* | ||||||||||
4+TIGIT+ | Abs_Value | 25 | 25 | 0 | 93.69 | 50.24 | 73.99 - 113.38 | 14.67 - 216.64 | 95.41 | 52.98 - 120.07 | Н/П* | Н/П* | ||||||||||
4NV | Abs_Value | 25 | 25 | 0 | 59.45 | 55.09 | 37.86 - 81.05 | 4.48 - 237.61 | 41.58 | 22.62 - 88.96 | Н/П* | Н/П* | ||||||||||
4NV(СТАР2) | Abs_Value | 25 | 25 | 0 | 53.26 | 52.95 | 32.5 - 74.02 | 3.89 - 222.55 | 32.64 | 13.42 - 88.36 | Н/П* | Н/П* | ||||||||||
4NV_TH1 | Abs_Value | 25 | 25 | 0 | 3.11 | 2.72 | 2.05 - 4.18 | 0.07 - 9.51 | 2.24 | 0.8 - 4.69 | Н/П* | Н/П* | ||||||||||
4NV_TH17 | Abs_Value | 25 | 25 | 0 | 1.55 | 1.46 | 0.98 - 2.12 | 0.21 - 7.19 | 1.07 | 0.67 - 2.07 | Н/П* | Н/П* | ||||||||||
4NV_Th17TO1 | Abs_Value | 25 | 25 | 0 | 0.29 | 0.27 | 0.19 - 0.4 | 0.01 - 0.98 | 0.18 | 0.08 - 0.47 | Н/П* | Н/П* | ||||||||||
4NV_TH2 | Abs_Value | 25 | 25 | 0 | 5.15 | 4.7 | 3.31 - 7 | 0.31 - 17.87 | 4.14 | 1.2 - 7.06 | Н/П* | Н/П* | ||||||||||
4NV_TH22 | Abs_Value | 25 | 25 | 0 | 0.33 | 0.63 | 0.09 - 0.58 | 0 - 2.8 | 0.14 | 0.02 - 0.23 | Н/П* | Н/П* | ||||||||||
4NV+226+ | Abs_Value | 25 | 25 | 0 | 47.3 | 50.15 | 27.64 - 66.96 | 3.83 - 221.43 | 31.18 | 10.03 - 73.8 | Н/П* | Н/П* | ||||||||||
4NV+39+ | Abs_Value | 25 | 25 | 0 | 1.82 | 2.11 | 0.99 - 2.64 | 0.01 - 8.35 | 1.27 | 0.52 - 2.01 | Н/П* | Н/П* | ||||||||||
4NV+DR+ | Abs_Value | 25 | 25 | 0 | 5.64 | 9.28 | 2 - 9.27 | 0.3 - 37.06 | 1.76 | 0.72 - 4.8 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 47.97 | 50.69 | 28.1 - 67.84 | 2.87 - 213.68 | 29.51 | 11.05 - 80.14 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 1.28 | 1.33 | 0.76 - 1.8 | 0.07 - 4.54 | 0.82 | 0.23 - 1.88 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 2.66 | 2.35 | 1.74 - 3.58 | 0.06 - 8.51 | 2.16 | 0.7 - 4.62 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 1.34 | 1.3 | 0.83 - 1.85 | 0 - 4.85 | 0.89 | 0.43 - 1.66 | Н/П* | Н/П* | ||||||||||
4NV+PD1+ | Abs_Value | 25 | 25 | 0 | 4 | 3.45 | 2.65 - 5.36 | 0.09 - 13.36 | 3.04 | 1.59 - 6.34 | Н/П* | Н/П* | ||||||||||
4NV+TIGIT+ | Abs_Value | 25 | 25 | 0 | 2.63 | 2.37 | 1.7 - 3.56 | 0.25 - 9.38 | 1.69 | 0.89 - 4 | Н/П* | Н/П* | ||||||||||
4ЕМ | Abs_Value | 25 | 25 | 0 | 15.22 | 19.1 | 7.73 - 22.71 | 0.09 - 72.83 | 9.43 | 2.27 - 17.96 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH1 | Abs_Value | 25 | 25 | 0 | 3.81 | 5.49 | 1.66 - 5.96 | 0.02 - 22.18 | 0.97 | 0.49 - 5.17 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH17 | Abs_Value | 25 | 25 | 0 | 0.06 | 0.13 | 0.01 - 0.11 | 0 - 0.59 | 0.01 | 0 - 0.04 | Н/П* | Н/П* | ||||||||||
4ЕМ_Th17TO1 | Abs_Value | 25 | 25 | 0 | 0.12 | 0.18 | 0.05 - 0.19 | 0 - 0.62 | 0.04 | 0.01 - 0.13 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH2 | Abs_Value | 25 | 25 | 0 | 0.61 | 1.02 | 0.21 - 1.01 | 0 - 4.75 | 0.14 | 0.04 - 0.82 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH22 | Abs_Value | 25 | 25 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.13 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ЕМ+226+ | Abs_Value | 25 | 25 | 0 | 132.71 | 80.8 | 101.04 - 164.39 | 14.74 - 377.13 | 111.79 | 84.69 - 160.46 | Н/П* | Н/П* | ||||||||||
4ЕМ+39+ | Abs_Value | 25 | 25 | 0 | 50 | 45.87 | 32.01 - 67.98 | 0.71 - 224.9 | 45.43 | 20.01 - 70.49 | Н/П* | Н/П* | ||||||||||
4ЕМ+DR+ | Abs_Value | 25 | 25 | 0 | 78.78 | 58.01 | 56.04 - 101.52 | 10.43 - 286.47 | 68.2 | 44.3 - 88.66 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT- | Abs_Value | 25 | 25 | 0 | 25.76 | 20.32 | 17.79 - 33.73 | 2.51 - 88.41 | 27.57 | 7.35 - 35.72 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 4.14 | 5.03 | 2.17 - 6.11 | 0.34 - 23.64 | 2.5 | 1.05 - 4.75 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+ | Abs_Value | 25 | 25 | 0 | 108.73 | 71.45 | 80.73 - 136.74 | 13.21 - 337.48 | 97.98 | 58.91 - 132.51 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT- | Abs_Value | 25 | 25 | 0 | 63.06 | 44.82 | 45.49 - 80.63 | 7.96 - 196.34 | 51.81 | 33.43 - 77.66 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 45.67 | 32.49 | 32.94 - 58.41 | 5.26 - 141.13 | 35.6 | 20.06 - 64.51 | Н/П* | Н/П* | ||||||||||
4ЕМ+TIGIT+ | Abs_Value | 25 | 25 | 0 | 49.81 | 35.48 | 35.9 - 63.72 | 5.74 - 149.98 | 39.47 | 21.38 - 64.84 | Н/П* | Н/П* | ||||||||||
4ЕМTM | Abs_Value | 25 | 25 | 0 | 138.63 | 83 | 106.1 - 171.17 | 16.21 - 387.82 | 118.34 | 88.22 - 172.43 | Н/П* | Н/П* | ||||||||||
4СМ | Abs_Value | 25 | 25 | 0 | 78.18 | 48 | 59.37 - 97 | 11.92 - 198.01 | 73.12 | 43.13 - 103.34 | Н/П* | Н/П* | ||||||||||
4СМ(СТАР2) | Abs_Value | 25 | 25 | 0 | 59.67 | 36.54 | 45.35 - 73.99 | 2.49 - 132.74 | 61.2 | 36.49 - 76.35 | Н/П* | Н/П* | ||||||||||
4СМ_TH1 | Abs_Value | 25 | 25 | 0 | 3.24 | 2.9 | 2.1 - 4.38 | 0.16 - 10.97 | 2.47 | 1.01 - 4.11 | Н/П* | Н/П* | ||||||||||
4СМ_TH17 | Abs_Value | 25 | 25 | 0 | 9.24 | 5.27 | 7.18 - 11.31 | 1.77 - 19.65 | 9.32 | 4.72 - 13.61 | Н/П* | Н/П* | ||||||||||
4СМ_Th17TO1 | Abs_Value | 25 | 25 | 0 | 0.99 | 1.06 | 0.58 - 1.41 | 0.07 - 4.84 | 0.7 | 0.25 - 1.41 | Н/П* | Н/П* | ||||||||||
4СМ_TH2 | Abs_Value | 25 | 25 | 0 | 6.96 | 7.36 | 4.07 - 9.84 | 0.79 - 29.39 | 4.68 | 2.11 - 7.6 | Н/П* | Н/П* | ||||||||||
4СМ_TH22 | Abs_Value | 25 | 25 | 0 | 1.65 | 1.92 | 0.9 - 2.4 | 0.03 - 7.43 | 1.02 | 0.52 - 1.23 | Н/П* | Н/П* | ||||||||||
4СМ+226+ | Abs_Value | 25 | 25 | 0 | 56.59 | 34.4 | 43.1 - 70.07 | 2.12 - 125.18 | 57.79 | 33.85 - 71.78 | Н/П* | Н/П* | ||||||||||
4СМ+39+ | Abs_Value | 25 | 25 | 0 | 18.81 | 15.5 | 12.73 - 24.89 | 0.07 - 49.53 | 15.95 | 3.9 - 35.62 | Н/П* | Н/П* | ||||||||||
4СМ+DR+ | Abs_Value | 25 | 25 | 0 | 18.62 | 15.78 | 12.43 - 24.8 | 0.13 - 54.42 | 13.43 | 6.54 - 28.21 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT- | Abs_Value | 25 | 25 | 0 | 19.47 | 16.23 | 13.11 - 25.83 | 0.75 - 58.09 | 16.18 | 6.62 - 29.33 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 2.82 | 2.62 | 1.8 - 3.85 | 0.03 - 8.27 | 1.65 | 0.74 - 5.23 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+ | Abs_Value | 25 | 25 | 0 | 37.38 | 23.64 | 28.11 - 46.65 | 0.25 - 85.43 | 34.06 | 18.31 - 51.53 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT- | Abs_Value | 25 | 25 | 0 | 16.56 | 12.88 | 11.51 - 21.61 | 0.11 - 53.01 | 11.48 | 8.77 - 21.87 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 20.82 | 12.6 | 15.88 - 25.76 | 0.14 - 43.85 | 22.44 | 8.69 - 29.97 | Н/П* | Н/П* | ||||||||||
4СМ+TIGIT+ | Abs_Value | 25 | 25 | 0 | 23.64 | 13.8 | 18.23 - 29.05 | 0.29 - 46.52 | 26.56 | 10.49 - 34.71 | Н/П* | Н/П* | ||||||||||
4ТM_TH1 | Abs_Value | 25 | 25 | 0 | 13.08 | 9.46 | 9.38 - 16.79 | 1.35 - 30.38 | 9.27 | 4.69 - 20.15 | Н/П* | Н/П* | ||||||||||
4ТM_TH17 | Abs_Value | 25 | 25 | 0 | 11.34 | 10.3 | 7.3 - 15.38 | 1.71 - 44.13 | 7.67 | 5.11 - 11.72 | Н/П* | Н/П* | ||||||||||
4ТM_Th17TO1 | Abs_Value | 25 | 25 | 0 | 3.97 | 4.14 | 2.34 - 5.59 | 0.27 - 18.81 | 2.41 | 1.67 - 4.26 | Н/П* | Н/П* | ||||||||||
4ТM_TH2 | Abs_Value | 25 | 25 | 0 | 9.21 | 17.57 | 2.33 - 16.1 | 0.45 - 85.75 | 4.09 | 2.14 - 8.69 | Н/П* | Н/П* | ||||||||||
4ТM_TH22 | Abs_Value | 25 | 25 | 0 | 6.69 | 6.49 | 4.14 - 9.23 | 0.16 - 30.35 | 4.96 | 2.64 - 8.68 | Н/П* | Н/П* | ||||||||||
4ТREG | Abs_Value | 25 | 25 | 0 | 4.55 | 4.75 | 2.69 - 6.42 | 0.17 - 15.12 | 2.33 | 1.41 - 5.5 | Н/П* | Н/П* | ||||||||||
4ТREG(СТАР2) | Abs_Value | 25 | 25 | 0 | 124.67 | 57.17 | 102.25 - 147.08 | 17.21 - 253.28 | 119.85 | 81.78 - 149.18 | Н/П* | Н/П* | ||||||||||
4ТREG_TH1 | Abs_Value | 25 | 25 | 0 | 0.31 | 0.21 | 0.22 - 0.39 | 0 - 0.83 | 0.23 | 0.17 - 0.41 | Н/П* | Н/П* | ||||||||||
4ТREG_TH17 | Abs_Value | 25 | 25 | 0 | 6.35 | 6.5 | 3.8 - 8.9 | 0.56 - 33.26 | 4.59 | 2.68 - 6.76 | Н/П* | Н/П* | ||||||||||
4ТREG_Th17TO1 | Abs_Value | 25 | 25 | 0 | 0.11 | 0.12 | 0.07 - 0.16 | 0 - 0.41 | 0.06 | 0.02 - 0.16 | Н/П* | Н/П* | ||||||||||
4ТREG_TH2 | Abs_Value | 25 | 25 | 0 | 3.47 | 3.49 | 2.11 - 4.84 | 0.25 - 17.5 | 2.55 | 1.61 - 3.8 | Н/П* | Н/П* | ||||||||||
4ТREG_TH22 | Abs_Value | 25 | 25 | 0 | 5.76 | 6.51 | 3.2 - 8.31 | 0.28 - 27.55 | 3.6 | 1.78 - 7.3 | Н/П* | Н/П* | ||||||||||
4ТЕ | Abs_Value | 25 | 25 | 0 | 11.9 | 17.25 | 5.14 - 18.66 | 0.09 - 58.86 | 4.5 | 0.69 - 12.45 | Н/П* | Н/П* | ||||||||||
4ТЕ(СТАР2) | Abs_Value | 25 | 25 | 0 | 50.4 | 40.13 | 34.67 - 66.13 | 7.25 - 172.13 | 43.71 | 18.43 - 63.13 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH1 | Abs_Value | 25 | 25 | 0 | 2.02 | 3.2 | 0.76 - 3.27 | 0.01 - 10.1 | 0.52 | 0.13 - 1.84 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH17 | Abs_Value | 25 | 25 | 0 | 0.02 | 0.04 | 0.01 - 0.04 | 0 - 0.16 | 0 | 0 - 0.03 | Н/П* | Н/П* | ||||||||||
4ТЕ_Th17TO1 | Abs_Value | 25 | 25 | 0 | 0.08 | 0.16 | 0.02 - 0.15 | 0 - 0.61 | 0.01 | 0 - 0.06 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH2 | Abs_Value | 25 | 25 | 0 | 0.73 | 1.98 | -0.04 - 1.51 | 0 - 9.46 | 0.07 | 0.01 - 0.35 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH22 | Abs_Value | 25 | 25 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.07 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ+226+ | Abs_Value | 25 | 25 | 0 | 46.05 | 37.07 | 31.52 - 60.59 | 4.81 - 157.81 | 34.32 | 16.83 - 55.87 | Н/П* | Н/П* | ||||||||||
4ТЕ+39+ | Abs_Value | 25 | 25 | 0 | 14.6 | 20.15 | 6.7 - 22.5 | 0.22 - 95.56 | 9.76 | 2.35 - 17.25 | Н/П* | Н/П* | ||||||||||
4ТЕ+DR+ | Abs_Value | 25 | 25 | 0 | 30.46 | 30.03 | 18.69 - 42.23 | 1.44 - 116.89 | 20.47 | 8.45 - 44.76 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 15.13 | 14.11 | 9.6 - 20.66 | 2.1 - 56.74 | 10.33 | 5.61 - 18.87 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 3.58 | 4.89 | 1.66 - 5.49 | 0.12 - 23.61 | 2.14 | 0.94 - 3.94 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+ | Abs_Value | 25 | 25 | 0 | 31.69 | 27.12 | 21.06 - 42.32 | 3.94 - 91.79 | 23.98 | 10.09 - 46.99 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 18.29 | 16.74 | 11.73 - 24.85 | 1.07 - 61.87 | 9.57 | 5.85 - 25.01 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 13.4 | 13.04 | 8.29 - 18.51 | 1.84 - 53.98 | 7.5 | 4.05 - 19.89 | Н/П* | Н/П* | ||||||||||
4ТЕ+TIGIT+ | Abs_Value | 25 | 25 | 0 | 16.98 | 17.1 | 10.27 - 23.68 | 2.16 - 77.59 | 9.52 | 5.84 - 22.91 | Н/П* | Н/П* | ||||||||||
4ТМ | Abs_Value | 25 | 25 | 0 | 126.88 | 66 | 101 - 152.75 | 21.41 - 291.47 | 116.87 | 85.67 - 147 | Н/П* | Н/П* | ||||||||||
8+ | Abs_Value | 25 | 25 | 0 | 498.65 | 380.89 | 349.34 - 647.96 | 1.92 - 1531.11 | 465.29 | 212.98 - 655.91 | Н/П* | Н/П* | ||||||||||
8+ (IM STAT) | Abs_Value | 25 | 25 | 0 | 631.78 | 466.48 | 448.92 - 814.64 | 2.46 - 1698.96 | 591.33 | 265.98 - 867.29 | Н/П* | Н/П* | ||||||||||
8+226+ | Abs_Value | 25 | 25 | 0 | 814.06 | 535.69 | 604.07 - 1024.05 | 19.37 - 1852.8 | 729.4 | 398.53 - 1197.61 | Н/П* | Н/П* | ||||||||||
8+39+ | Abs_Value | 25 | 25 | 0 | 129.07 | 99.17 | 90.2 - 167.95 | 0.32 - 376.08 | 118.53 | 39.62 - 192.09 | Н/П* | Н/П* | ||||||||||
8+DR+ | Abs_Value | 25 | 25 | 0 | 651.17 | 434.05 | 481.02 - 821.32 | 13.26 - 1528.67 | 612.95 | 326.33 - 927.99 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 248.99 | 224.98 | 160.79 - 337.18 | 3.06 - 946.44 | 216.46 | 92.27 - 271.42 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 245.52 | 230.44 | 155.18 - 335.85 | 2.47 - 1005.42 | 192.22 | 72.97 - 331.8 | Н/П* | Н/П* | ||||||||||
8+PD-1+ | Abs_Value | 25 | 25 | 0 | 407.97 | 320.62 | 282.28 - 533.65 | 15.39 - 1058.56 | 284.89 | 148.47 - 599.28 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 134.3 | 139 | 79.81 - 188.79 | 1.56 - 459.85 | 88.41 | 25.85 - 205.09 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 273.67 | 208.59 | 191.9 - 355.44 | 10.91 - 761.58 | 216.27 | 111.37 - 411.76 | Н/П* | Н/П* | ||||||||||
8+TIGIT+ | Abs_Value | 25 | 25 | 0 | 519.19 | 361.77 | 377.37 - 661 | 13.76 - 1510.56 | 440.22 | 286.58 - 740.07 | Н/П* | Н/П* | ||||||||||
8EMTM | Abs_Value | 25 | 25 | 0 | 153.27 | 133.38 | 100.98 - 205.56 | 1.17 - 410.17 | 107.03 | 55.31 - 248.39 | Н/П* | Н/П* | ||||||||||
8EMTM+226+ | Abs_Value | 25 | 25 | 0 | 131.1 | 115.53 | 85.81 - 176.39 | 0.94 - 359.16 | 91.21 | 32.65 - 222.03 | Н/П* | Н/П* | ||||||||||
8EMTM+39+ | Abs_Value | 25 | 25 | 0 | 33.29 | 37.04 | 18.77 - 47.81 | 0.19 - 141.21 | 23.35 | 3.51 - 49.02 | Н/П* | Н/П* | ||||||||||
8EMTM+DR+ | Abs_Value | 25 | 25 | 0 | 127.59 | 109.66 | 84.6 - 170.57 | 0.88 - 335.96 | 89.9 | 51 - 214.35 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 30.74 | 38.35 | 15.71 - 45.78 | 0.1 - 179.93 | 19.92 | 7.51 - 44.09 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 30.4 | 37.31 | 15.78 - 45.03 | 0.16 - 117.39 | 12.39 | 6.97 - 47.2 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+ | Abs_Value | 25 | 25 | 0 | 92.12 | 83.1 | 59.55 - 124.7 | 0.9 - 285.03 | 57.46 | 30.15 - 154.36 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 29.46 | 31.22 | 17.22 - 41.71 | 0.17 - 100.3 | 16.91 | 4.9 - 39.89 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 62.66 | 60.31 | 39.02 - 86.3 | 0.73 - 237.56 | 42.98 | 13.9 - 97.09 | Н/П* | Н/П* | ||||||||||
8EMTM+TIGIT+ | Abs_Value | 25 | 25 | 0 | 93.06 | 89.71 | 57.89 - 128.23 | 0.9 - 307.05 | 57.53 | 21.15 - 129.95 | Н/П* | Н/П* | ||||||||||
8NV | Abs_Value | 25 | 25 | 0 | 33.21 | 33.93 | 19.91 - 46.51 | 0.67 - 133.23 | 21.08 | 13.74 - 46.67 | Н/П* | Н/П* | ||||||||||
8NV(СТАР2) | Abs_Value | 25 | 25 | 0 | 27.96 | 36.41 | 13.69 - 42.24 | 1.05 - 179.03 | 16.26 | 10.73 - 29.41 | Н/П* | Н/П* | ||||||||||
8NV+226+ | Abs_Value | 25 | 25 | 0 | 24.54 | 34.6 | 10.98 - 38.11 | 0.95 - 177.03 | 15.01 | 8.92 - 27.06 | Н/П* | Н/П* | ||||||||||
8NV+39+ | Abs_Value | 25 | 25 | 0 | 1.92 | 1.63 | 1.28 - 2.56 | 0.01 - 5.99 | 1.53 | 0.58 - 2.96 | Н/П* | Н/П* | ||||||||||
8NV+DR+ | Abs_Value | 25 | 25 | 0 | 6.24 | 10.17 | 2.25 - 10.23 | 0.38 - 48.85 | 2.94 | 1.04 - 5.9 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 19.4 | 34.27 | 5.97 - 32.83 | 0.23 - 174.66 | 11.05 | 4.45 - 20.75 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 3.48 | 8.65 | 0.09 - 6.87 | 0 - 42.43 | 0.86 | 0.41 - 2.46 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+ | Abs_Value | 25 | 25 | 0 | 5.08 | 7.31 | 2.22 - 7.95 | 0.23 - 28.31 | 2.74 | 0.51 - 4.76 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 1.03 | 1.39 | 0.49 - 1.58 | 0.01 - 5.9 | 0.61 | 0.2 - 1.38 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 4.05 | 6.73 | 1.41 - 6.69 | 0.21 - 27.87 | 1.99 | 0.42 - 3.22 | Н/П* | Н/П* | ||||||||||
8NV+TIGIT+ | Abs_Value | 25 | 25 | 0 | 7.53 | 14.75 | 1.75 - 13.31 | 0.34 - 70.3 | 3.4 | 1.15 - 5.16 | Н/П* | Н/П* | ||||||||||
8TREG | Abs_Value | 25 | 25 | 0 | 493.78 | 393.53 | 339.52 - 648.05 | 1.91 - 1599.38 | 417.54 | 205.29 - 666.09 | Н/П* | Н/П* | ||||||||||
8ЕМ | Abs_Value | 25 | 25 | 0 | 140.54 | 128.18 | 90.3 - 190.79 | 0.54 - 545.89 | 110.91 | 33.4 - 214.98 | Н/П* | Н/П* | ||||||||||
8СМ | Abs_Value | 25 | 25 | 0 | 17.95 | 24.9 | 8.19 - 27.71 | 0.11 - 105.04 | 8.58 | 2.52 - 17.67 | Н/П* | Н/П* | ||||||||||
8СМ(СТАР2) | Abs_Value | 25 | 25 | 0 | 13.52 | 19.22 | 5.98 - 21.05 | 0.09 - 72.63 | 6.1 | 0.61 - 16.26 | Н/П* | Н/П* | ||||||||||
8СМ+226+ | Abs_Value | 25 | 25 | 0 | 10.31 | 13.06 | 5.2 - 15.43 | 0.09 - 45.56 | 5.66 | 0.57 - 14.18 | Н/П* | Н/П* | ||||||||||
8СМ+39+ | Abs_Value | 25 | 25 | 0 | 3.82 | 5.9 | 1.5 - 6.13 | 0.02 - 27.07 | 1.25 | 0.22 - 5.33 | Н/П* | Н/П* | ||||||||||
8СМ+DR+ | Abs_Value | 25 | 25 | 0 | 11.17 | 17.18 | 4.43 - 17.9 | 0.04 - 66.63 | 3.76 | 0.49 - 13.92 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 2.36 | 4.33 | 0.66 - 4.06 | 0.01 - 19.15 | 1.08 | 0.24 - 1.78 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 3.03 | 5.92 | 0.71 - 5.35 | 0.01 - 20.43 | 0.68 | 0.14 - 1.28 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+ | Abs_Value | 25 | 25 | 0 | 8.13 | 12.1 | 3.39 - 12.87 | 0.04 - 47.52 | 2.83 | 0.56 - 10.63 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 0.87 | 1.26 | 0.37 - 1.36 | 0.01 - 4.51 | 0.39 | 0.09 - 0.98 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 7.26 | 11.71 | 2.67 - 11.85 | 0.03 - 47.06 | 2.6 | 0.47 - 9.47 | Н/П* | Н/П* | ||||||||||
8СМ+TIGIT+ | Abs_Value | 25 | 25 | 0 | 10.29 | 16.53 | 3.81 - 16.77 | 0.05 - 67.49 | 3.33 | 0.5 - 11.66 | Н/П* | Н/П* | ||||||||||
8ТЕ | Abs_Value | 25 | 25 | 0 | 526.75 | 392.68 | 372.82 - 680.68 | 6.82 - 1431.59 | 493.67 | 225.49 - 711.59 | Н/П* | Н/П* | ||||||||||
8ТЕ(СТАР2) | Abs_Value | 25 | 25 | 0 | 704.23 | 474.15 | 518.36 - 890.1 | 9.74 - 1753.87 | 671.37 | 292.51 - 1022.83 | Н/П* | Н/П* | ||||||||||
8ТЕ+226+ | Abs_Value | 25 | 25 | 0 | 645.4 | 455.86 | 466.71 - 824.1 | 9.12 - 1680.66 | 581.45 | 261.89 - 979.95 | Н/П* | Н/П* | ||||||||||
8ТЕ+39+ | Abs_Value | 25 | 25 | 0 | 88.98 | 65.87 | 63.16 - 114.8 | 0.09 - 223.92 | 77.45 | 22.4 - 137.03 | Н/П* | Н/П* | ||||||||||
8ТЕ+DR+ | Abs_Value | 25 | 25 | 0 | 504.45 | 358.36 | 363.97 - 644.93 | 5.03 - 1408.92 | 489.78 | 214.85 - 707.77 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT- | Abs_Value | 25 | 25 | 0 | 195.18 | 190 | 120.7 - 269.66 | 2.48 - 718.37 | 161.26 | 68.44 - 228.42 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT+ | Abs_Value | 25 | 25 | 0 | 207.54 | 191.78 | 132.36 - 282.71 | 1.65 - 830 | 165.2 | 64.29 - 316.92 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+ | Abs_Value | 25 | 25 | 0 | 301.51 | 262.45 | 198.63 - 404.39 | 5.61 - 959.6 | 209.97 | 111.48 - 427.65 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT- | Abs_Value | 25 | 25 | 0 | 103.07 | 115.9 | 57.64 - 148.5 | 1.36 - 388.34 | 52.08 | 15.99 - 159.29 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT+ | Abs_Value | 25 | 25 | 0 | 198.44 | 163.25 | 134.45 - 262.44 | 3.52 - 571.26 | 139.35 | 75.68 - 315.01 | Н/П* | Н/П* | ||||||||||
8ТЕ+TIGIT+ | Abs_Value | 25 | 25 | 0 | 405.98 | 282.45 | 295.26 - 516.7 | 5.17 - 1145.01 | 322.14 | 207.82 - 585.29 | Н/П* | Н/П* | ||||||||||
8ТМ | Abs_Value | 25 | 25 | 0 | 60 | 52.55 | 39.4 - 80.6 | 1.16 - 174.35 | 46.8 | 15.99 - 80.83 | Н/П* | Н/П* | ||||||||||
TREG_CM | Abs_Value | 25 | 25 | 0 | 2.85 | 3.16 | 1.61 - 4.09 | 0.08 - 14.1 | 1.69 | 0.82 - 5.02 | Н/П* | Н/П* | ||||||||||
TREG_EMTM | Abs_Value | 25 | 25 | 0 | 26.47 | 20.09 | 18.6 - 34.35 | 1.78 - 71.51 | 18.06 | 12.84 - 38.69 | Н/П* | Н/П* | ||||||||||
TREG_NV | Abs_Value | 25 | 25 | 0 | 2.08 | 1.86 | 1.35 - 2.81 | 0 - 5.4 | 1.27 | 0.52 - 3.17 | Н/П* | Н/П* | ||||||||||
TREG_TE | Abs_Value | 25 | 25 | 0 | 7.28 | 6.07 | 4.9 - 9.67 | 0.53 - 26.44 | 6.27 | 2.86 - 10.36 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT- | Abs_Value | 25 | 25 | 0 | 1.62 | 1.28 | 1.12 - 2.12 | 0.12 - 4.76 | 1.5 | 0.65 - 2.33 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT+ | Abs_Value | 25 | 25 | 0 | 9.08 | 7.58 | 6.11 - 12.05 | 0.46 - 26.78 | 7.51 | 3.39 - 12.27 | Н/П* | Н/П* | ||||||||||
TREG+226+ | Abs_Value | 25 | 25 | 0 | 28.24 | 19.1 | 20.76 - 35.73 | 2.27 - 67.09 | 23.95 | 14.49 - 38.08 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT- | Abs_Value | 25 | 25 | 0 | 3.15 | 1.96 | 2.38 - 3.92 | 0.49 - 6.55 | 3.21 | 1.26 - 4.58 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT+ | Abs_Value | 25 | 25 | 0 | 25.1 | 17.57 | 18.21 - 31.98 | 1.77 - 60.99 | 20.4 | 12.88 - 33.39 | Н/П* | Н/П* | ||||||||||
TREG+39+ | Abs_Value | 25 | 25 | 0 | 28.72 | 19.78 | 20.97 - 36.48 | 1.42 - 83.91 | 24.01 | 17.28 - 37.7 | Н/П* | Н/П* | ||||||||||
TREG+DR+ | Abs_Value | 25 | 25 | 0 | 30.1 | 21.09 | 21.84 - 38.37 | 2.28 - 75.55 | 26.18 | 14.64 - 46.59 | Н/П* | Н/П* | ||||||||||
TREG+PD-1+ | Abs_Value | 25 | 25 | 0 | 17.15 | 13.87 | 11.71 - 22.58 | 0.47 - 49.25 | 13.78 | 6.67 - 21.27 | Н/П* | Н/П* | ||||||||||
TREG+TIGIT+ | Abs_Value | 25 | 25 | 0 | 34.18 | 23.64 | 24.91 - 43.45 | 2.24 - 85.67 | 28.53 | 17.3 - 48.19 | Н/П* | Н/П* | ||||||||||
ДЕНЬ ХРРТПХ +180 | 4_TFH | Abs_Value | 8 | 8 | 0 | 58.53 | 30.95 | 37.08 - 79.97 | 4.33 - 100.17 | 64.6 | 47.58 - 74.95 | Н/П* | Н/П* | |||||||||
4_TH1 | Abs_Value | 8 | 8 | 0 | 52.88 | 45.82 | 21.12 - 84.63 | 5.76 - 139.51 | 36.23 | 26.33 - 62.23 | Н/П* | Н/П* | ||||||||||
4_TH17 | Abs_Value | 8 | 8 | 0 | 38.59 | 34.42 | 14.74 - 62.45 | 2.67 - 109.23 | 29.75 | 15.91 - 48.75 | Н/П* | Н/П* | ||||||||||
4_Th17TO1 | Abs_Value | 8 | 8 | 0 | 13.55 | 11.87 | 5.32 - 21.78 | 0.52 - 39.95 | 11.73 | 8.79 - 14.84 | Н/П* | Н/П* | ||||||||||
4_TH2 | Abs_Value | 8 | 8 | 0 | 27.12 | 24.59 | 10.08 - 44.16 | 3.71 - 80.42 | 17.94 | 14.69 - 28.01 | Н/П* | Н/П* | ||||||||||
4_TH22 | Abs_Value | 8 | 8 | 0 | 16.82 | 15.81 | 5.86 - 27.77 | 0.47 - 43.52 | 13.74 | 4.49 - 23.15 | Н/П* | Н/П* | ||||||||||
4+ | Abs_Value | 8 | 8 | 0 | 205.27 | 137.06 | 110.3 - 300.25 | 27.34 - 489.56 | 190.56 | 125.9 - 246.2 | Н/П* | Н/П* | ||||||||||
4+ (IM STAT) | Abs_Value | 8 | 8 | 0 | 174.71 | 118.7 | 92.46 - 256.97 | 21.35 - 418.46 | 161.61 | 105.77 - 208.22 | Н/П* | Н/П* | ||||||||||
4+226+ | Abs_Value | 8 | 8 | 0 | 432.98 | 214.56 | 284.3 - 581.66 | 58.67 - 689.45 | 488.08 | 298.46 - 546.5 | Н/П* | Н/П* | ||||||||||
4+39+ | Abs_Value | 8 | 8 | 0 | 114.8 | 142.15 | 16.29 - 213.3 | 6.16 - 379.73 | 55.9 | 20.16 - 143.57 | Н/П* | Н/П* | ||||||||||
4+DR+ | Abs_Value | 8 | 8 | 0 | 197.76 | 167.54 | 81.66 - 313.86 | 6.74 - 444.36 | 163.5 | 72.37 - 295.08 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 206.19 | 112.04 | 128.55 - 283.83 | 31.34 - 339.45 | 224.31 | 130.99 - 288.22 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 16.48 | 11.95 | 8.21 - 24.76 | 2.07 - 40.26 | 17.21 | 7.4 - 20.31 | Н/П* | Н/П* | ||||||||||
4+PD-1+ | Abs_Value | 8 | 8 | 0 | 238.14 | 155.46 | 130.41 - 345.87 | 26.44 - 477.88 | 228.22 | 126.89 - 358.38 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 148.9 | 112.95 | 70.63 - 227.18 | 15.97 - 335.51 | 125.94 | 65.84 - 232.62 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 89.24 | 47.33 | 56.44 - 122.03 | 10.47 - 142.37 | 104.53 | 57.68 - 125.2 | Н/П* | Н/П* | ||||||||||
4+TIGIT+ | Abs_Value | 8 | 8 | 0 | 105.72 | 51.47 | 70.05 - 141.39 | 12.54 - 150.32 | 124.1 | 89.31 - 142.76 | Н/П* | Н/П* | ||||||||||
4NV | Abs_Value | 8 | 8 | 0 | 93.17 | 65.58 | 47.73 - 138.61 | 19.14 - 205.24 | 71.98 | 45.66 - 143.14 | Н/П* | Н/П* | ||||||||||
4NV(СТАР2) | Abs_Value | 8 | 8 | 0 | 87.06 | 67.44 | 40.32 - 133.8 | 15.78 - 204.98 | 75.64 | 29.46 - 122.75 | Н/П* | Н/П* | ||||||||||
4NV_TH1 | Abs_Value | 8 | 8 | 0 | 6.12 | 5.65 | 2.21 - 10.04 | 0.75 - 18.23 | 5.36 | 2.44 - 7.52 | Н/П* | Н/П* | ||||||||||
4NV_TH17 | Abs_Value | 8 | 8 | 0 | 1.8 | 0.86 | 1.21 - 2.4 | 0.5 - 2.92 | 1.57 | 1.29 - 2.59 | Н/П* | Н/П* | ||||||||||
4NV_Th17TO1 | Abs_Value | 8 | 8 | 0 | 0.61 | 0.34 | 0.38 - 0.85 | 0.09 - 1.14 | 0.55 | 0.43 - 0.78 | Н/П* | Н/П* | ||||||||||
4NV_TH2 | Abs_Value | 8 | 8 | 0 | 4.96 | 3.85 | 2.29 - 7.63 | 1.43 - 13.51 | 4.14 | 2.61 - 5.87 | Н/П* | Н/П* | ||||||||||
4NV_TH22 | Abs_Value | 8 | 8 | 0 | 0.14 | 0.2 | 0 - 0.28 | 0 - 0.63 | 0.08 | 0.03 - 0.13 | Н/П* | Н/П* | ||||||||||
4NV+226+ | Abs_Value | 8 | 8 | 0 | 76.75 | 65.59 | 31.3 - 122.2 | 15.45 - 203.08 | 56.76 | 25.71 - 109.58 | Н/П* | Н/П* | ||||||||||
4NV+39+ | Abs_Value | 8 | 8 | 0 | 2.28 | 3.15 | 0.09 - 4.46 | 0.09 - 9.72 | 1.37 | 0.51 - 2.32 | Н/П* | Н/П* | ||||||||||
4NV+DR+ | Abs_Value | 8 | 8 | 0 | 6.77 | 4.31 | 3.78 - 9.76 | 0.2 - 11.36 | 7.33 | 3.62 - 10.86 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 79.19 | 64.15 | 34.73 - 123.64 | 14.59 - 193.32 | 66.91 | 27.72 - 106.01 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 1.66 | 1.64 | 0.52 - 2.8 | 0.35 - 5.35 | 1.06 | 0.8 - 1.67 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 4.6 | 5.7 | 0.65 - 8.55 | 0.4 - 17.59 | 3.03 | 1.04 - 5.15 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 1.62 | 1.45 | 0.62 - 2.62 | 0.17 - 4.37 | 1.73 | 0.25 - 2.24 | Н/П* | Н/П* | ||||||||||
4NV+PD1+ | Abs_Value | 8 | 8 | 0 | 6.21 | 6.46 | 1.74 - 10.69 | 0.59 - 19.7 | 4.91 | 1.24 - 8.58 | Н/П* | Н/П* | ||||||||||
4NV+TIGIT+ | Abs_Value | 8 | 8 | 0 | 3.28 | 2.72 | 1.39 - 5.16 | 0.62 - 7.58 | 2.76 | 1.01 - 4.46 | Н/П* | Н/П* | ||||||||||
4ЕМ | Abs_Value | 8 | 8 | 0 | 22.52 | 34.85 | -1.63 - 46.68 | 1.83 - 101.46 | 7.62 | 3.66 - 18.69 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH1 | Abs_Value | 8 | 8 | 0 | 10.41 | 17.96 | -2.04 - 22.85 | 0.23 - 52.73 | 2.65 | 1.26 - 8.81 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH17 | Abs_Value | 8 | 8 | 0 | 0.02 | 0.03 | -0.01 - 0.04 | 0 - 0.1 | 0.01 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ЕМ_Th17TO1 | Abs_Value | 8 | 8 | 0 | 0.1 | 0.07 | 0.05 - 0.15 | 0 - 0.2 | 0.1 | 0.05 - 0.15 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH2 | Abs_Value | 8 | 8 | 0 | 0.47 | 0.76 | -0.05 - 1 | 0.02 - 2.26 | 0.13 | 0.07 - 0.5 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH22 | Abs_Value | 8 | 8 | 0 | 0 | 0 | 0 - 0 | 0 - 0.01 | 0 | 0 - 0 | Н/П* | Н/П* | ||||||||||
4ЕМ+226+ | Abs_Value | 8 | 8 | 0 | 213.97 | 149.24 | 110.55 - 317.39 | 23.82 - 444.2 | 247.06 | 80.19 - 304.9 | Н/П* | Н/П* | ||||||||||
4ЕМ+39+ | Abs_Value | 8 | 8 | 0 | 77.91 | 110.06 | 1.65 - 154.18 | 3.69 - 325.68 | 35.53 | 8.19 - 86.25 | Н/П* | Н/П* | ||||||||||
4ЕМ+DR+ | Abs_Value | 8 | 8 | 0 | 129.31 | 120.6 | 45.74 - 212.88 | 5.04 - 373.34 | 118.88 | 40.25 - 160.95 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT- | Abs_Value | 8 | 8 | 0 | 61.31 | 55.08 | 23.14 - 99.47 | 6.25 - 154.67 | 56.62 | 9.86 - 91.88 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 7.01 | 10.31 | -0.13 - 14.16 | 0.61 - 31.87 | 3.91 | 1.77 - 6.35 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+ | Abs_Value | 8 | 8 | 0 | 153.48 | 114.77 | 73.95 - 233.01 | 17.49 - 364.92 | 160.65 | 71.44 - 203.18 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT- | Abs_Value | 8 | 8 | 0 | 103.85 | 87.77 | 43.03 - 164.67 | 10.35 - 266.71 | 97.4 | 31.99 - 150 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 49.63 | 30.49 | 28.5 - 70.76 | 7.14 - 98.21 | 54.21 | 36.04 - 63.49 | Н/П* | Н/П* | ||||||||||
4ЕМ+TIGIT+ | Abs_Value | 8 | 8 | 0 | 56.64 | 34.43 | 32.79 - 80.5 | 7.75 - 100.36 | 61.16 | 38.96 - 78.79 | Н/П* | Н/П* | ||||||||||
4ЕМTM | Abs_Value | 8 | 8 | 0 | 221.8 | 153.13 | 115.69 - 327.92 | 24.35 - 452.24 | 261.67 | 83.92 - 313.95 | Н/П* | Н/П* | ||||||||||
4СМ | Abs_Value | 8 | 8 | 0 | 105.82 | 85.55 | 46.53 - 165.1 | 13.53 - 260.46 | 90.77 | 53.74 - 132.89 | Н/П* | Н/П* | ||||||||||
4СМ(СТАР2) | Abs_Value | 8 | 8 | 0 | 83.32 | 59.93 | 41.78 - 124.85 | 10.93 - 184.54 | 67.98 | 49.57 - 116.93 | Н/П* | Н/П* | ||||||||||
4СМ_TH1 | Abs_Value | 8 | 8 | 0 | 5.01 | 3.72 | 2.43 - 7.59 | 0.38 - 10.83 | 5.21 | 2.47 - 6.57 | Н/П* | Н/П* | ||||||||||
4СМ_TH17 | Abs_Value | 8 | 8 | 0 | 12.73 | 11.95 | 4.45 - 21.01 | 1.07 - 34.36 | 8.51 | 5.91 - 15.66 | Н/П* | Н/П* | ||||||||||
4СМ_Th17TO1 | Abs_Value | 8 | 8 | 0 | 2.1 | 1.47 | 1.08 - 3.11 | 0.06 - 4.39 | 1.89 | 1.23 - 3.02 | Н/П* | Н/П* | ||||||||||
4СМ_TH2 | Abs_Value | 8 | 8 | 0 | 10.33 | 14.82 | 0.06 - 20.6 | 1.12 - 45.88 | 5.88 | 2.99 - 7.9 | Н/П* | Н/П* | ||||||||||
4СМ_TH22 | Abs_Value | 8 | 8 | 0 | 2.49 | 4.52 | -0.65 - 5.62 | 0.17 - 13.33 | 0.55 | 0.33 - 1.69 | Н/П* | Н/П* | ||||||||||
4СМ+226+ | Abs_Value | 8 | 8 | 0 | 79.57 | 57.71 | 39.58 - 119.56 | 10.84 - 178.97 | 64.6 | 47.28 - 109.65 | Н/П* | Н/П* | ||||||||||
4СМ+39+ | Abs_Value | 8 | 8 | 0 | 24.52 | 39.26 | -2.68 - 51.73 | 0.7 - 118.64 | 10.4 | 3.23 - 23.72 | Н/П* | Н/П* | ||||||||||
4СМ+DR+ | Abs_Value | 8 | 8 | 0 | 25.78 | 24.1 | 9.08 - 42.48 | 0.72 - 64.82 | 18.55 | 9.27 - 36.47 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT- | Abs_Value | 8 | 8 | 0 | 28.9 | 21.97 | 13.68 - 44.13 | 6.03 - 68.44 | 20.78 | 14.22 - 39.45 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 4.4 | 3.18 | 2.2 - 6.6 | 0.45 - 8.85 | 4.32 | 1.57 - 6.77 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+ | Abs_Value | 8 | 8 | 0 | 50.01 | 39.97 | 22.31 - 77.71 | 3.36 - 122.72 | 44.08 | 25.57 - 73.81 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT- | Abs_Value | 8 | 8 | 0 | 22.23 | 17.51 | 10.09 - 34.36 | 1.56 - 55.65 | 21.54 | 11.54 - 29.87 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 27.78 | 23.32 | 11.62 - 43.95 | 1.8 - 67.07 | 20.45 | 14.02 - 44.31 | Н/П* | Н/П* | ||||||||||
4СМ+TIGIT+ | Abs_Value | 8 | 8 | 0 | 32.18 | 26.02 | 14.15 - 50.22 | 2.3 - 74.86 | 22.93 | 17.51 - 51.35 | Н/П* | Н/П* | ||||||||||
4ТM_TH1 | Abs_Value | 8 | 8 | 0 | 19.51 | 19.98 | 5.67 - 33.35 | 0.88 - 65.78 | 14.44 | 10.42 - 21.14 | Н/П* | Н/П* | ||||||||||
4ТM_TH17 | Abs_Value | 8 | 8 | 0 | 22.44 | 25.21 | 4.97 - 39.91 | 0.98 - 68.85 | 13.68 | 5.06 - 27.62 | Н/П* | Н/П* | ||||||||||
4ТM_Th17TO1 | Abs_Value | 8 | 8 | 0 | 9.76 | 11.07 | 2.09 - 17.43 | 0.18 - 35.59 | 6.91 | 5.21 - 9.69 | Н/П* | Н/П* | ||||||||||
4ТM_TH2 | Abs_Value | 8 | 8 | 0 | 8.68 | 11.09 | 0.99 - 16.37 | 0.78 - 33.45 | 4.33 | 1.8 - 9.67 | Н/П* | Н/П* | ||||||||||
4ТM_TH22 | Abs_Value | 8 | 8 | 0 | 12.51 | 12.63 | 3.75 - 21.26 | 0.22 - 38.35 | 9.62 | 3.27 - 17.13 | Н/П* | Н/П* | ||||||||||
4ТREG | Abs_Value | 8 | 8 | 0 | 3.38 | 3.33 | 1.08 - 5.69 | 0.52 - 9.96 | 2.06 | 1.18 - 4.33 | Н/П* | Н/П* | ||||||||||
4ТREG(СТАР2) | Abs_Value | 8 | 8 | 0 | 204.35 | 131.83 | 112.99 - 295.7 | 27.24 - 474.51 | 195.64 | 124.48 - 241.62 | Н/П* | Н/П* | ||||||||||
4ТREG_TH1 | Abs_Value | 8 | 8 | 0 | 0.35 | 0.25 | 0.17 - 0.52 | 0.1 - 0.82 | 0.29 | 0.14 - 0.44 | Н/П* | Н/П* | ||||||||||
4ТREG_TH17 | Abs_Value | 8 | 8 | 0 | 7.31 | 5.37 | 3.59 - 11.03 | 1.01 - 15.15 | 5.27 | 3.34 - 12.25 | Н/П* | Н/П* | ||||||||||
4ТREG_Th17TO1 | Abs_Value | 8 | 8 | 0 | 0.14 | 0.13 | 0.05 - 0.22 | 0.03 - 0.33 | 0.06 | 0.04 - 0.24 | Н/П* | Н/П* | ||||||||||
4ТREG_TH2 | Abs_Value | 8 | 8 | 0 | 2.82 | 1.72 | 1.62 - 4.01 | 1.04 - 6.08 | 2.8 | 1.28 - 3.61 | Н/П* | Н/П* | ||||||||||
4ТREG_TH22 | Abs_Value | 8 | 8 | 0 | 7.11 | 5.87 | 3.04 - 11.17 | 0.61 - 16.79 | 5.23 | 3.58 - 9.37 | Н/П* | Н/П* | ||||||||||
4ТЕ | Abs_Value | 8 | 8 | 0 | 20.66 | 39.04 | -6.39 - 47.71 | 0.47 - 114.7 | 3.04 | 0.82 - 20.35 | Н/П* | Н/П* | ||||||||||
4ТЕ(СТАР2) | Abs_Value | 8 | 8 | 0 | 66.94 | 63.13 | 23.19 - 110.68 | 8.27 - 207.55 | 60.47 | 23.6 - 74.9 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH1 | Abs_Value | 8 | 8 | 0 | 7.58 | 18.08 | -4.94 - 20.11 | 0.15 - 52.19 | 0.8 | 0.3 - 2.5 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH17 | Abs_Value | 8 | 8 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.01 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ_Th17TO1 | Abs_Value | 8 | 8 | 0 | 0.04 | 0.05 | 0 - 0.07 | 0 - 0.15 | 0.02 | 0 - 0.04 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH2 | Abs_Value | 8 | 8 | 0 | 0.56 | 0.89 | -0.06 - 1.18 | 0 - 2.33 | 0.11 | 0.01 - 0.64 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH22 | Abs_Value | 8 | 8 | 0 | 0 | 0 | 0 - 0 | 0 - 0.01 | 0 | 0 - 0 | Н/П* | Н/П* | ||||||||||
4ТЕ+226+ | Abs_Value | 8 | 8 | 0 | 61.16 | 62.06 | 18.15 - 104.16 | 8.06 - 202.6 | 51.87 | 19 - 66.98 | Н/П* | Н/П* | ||||||||||
4ТЕ+39+ | Abs_Value | 8 | 8 | 0 | 9.82 | 12.1 | 1.43 - 18.2 | 0.46 - 33.74 | 3.66 | 1.87 - 13.89 | Н/П* | Н/П* | ||||||||||
4ТЕ+DR+ | Abs_Value | 8 | 8 | 0 | 35.56 | 50.84 | 0.32 - 70.79 | 0.75 - 156.97 | 25 | 4.98 - 31.35 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 35.93 | 43.64 | 5.7 - 66.17 | 4.15 - 132.13 | 20.84 | 7.97 - 38.36 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 3.27 | 1.93 | 1.93 - 4.61 | 0.39 - 6.11 | 3.42 | 2.52 - 4.23 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+ | Abs_Value | 8 | 8 | 0 | 27.73 | 21.67 | 12.72 - 42.75 | 3.73 - 69.3 | 23.92 | 12.48 - 38.56 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 17.95 | 16.1 | 6.79 - 29.11 | 2.56 - 50.24 | 15.05 | 5 - 25.28 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 9.78 | 7.1 | 4.86 - 14.7 | 1.17 - 20.13 | 9.12 | 4.04 - 13.67 | Н/П* | Н/П* | ||||||||||
4ТЕ+TIGIT+ | Abs_Value | 8 | 8 | 0 | 13.05 | 8.5 | 7.16 - 18.94 | 1.56 - 25.17 | 12.54 | 7.22 - 18.44 | Н/П* | Н/П* | ||||||||||
4ТМ | Abs_Value | 8 | 8 | 0 | 197.18 | 140.24 | 100 - 294.36 | 17.69 - 412.31 | 221.7 | 76.18 - 269.6 | Н/П* | Н/П* | ||||||||||
8+ | Abs_Value | 8 | 8 | 0 | 523.34 | 519.66 | 163.23 - 883.44 | 59.76 - 1524.17 | 277.21 | 193.35 - 719.8 | Н/П* | Н/П* | ||||||||||
8+ (IM STAT) | Abs_Value | 8 | 8 | 0 | 644.48 | 596.98 | 230.79 - 1058.16 | 79.31 - 1806.25 | 379.1 | 320.21 - 790.62 | Н/П* | Н/П* | ||||||||||
8+226+ | Abs_Value | 8 | 8 | 0 | 874.92 | 701.97 | 388.48 - 1361.36 | 127.09 - 2191.35 | 644.85 | 432.11 - 1059.39 | Н/П* | Н/П* | ||||||||||
8+39+ | Abs_Value | 8 | 8 | 0 | 133.28 | 177.9 | 10 - 256.55 | 6.21 - 554.73 | 90.88 | 36.72 - 131.09 | Н/П* | Н/П* | ||||||||||
8+DR+ | Abs_Value | 8 | 8 | 0 | 623.87 | 537.07 | 251.69 - 996.04 | 31.3 - 1792.18 | 448.68 | 399.48 - 668.98 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 308.48 | 285.61 | 110.56 - 506.39 | 49.48 - 800.45 | 220.15 | 94.66 - 424.06 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 327.41 | 389.55 | 57.47 - 597.36 | 7.25 - 1202.9 | 218.74 | 86.19 - 402.2 | Н/П* | Н/П* | ||||||||||
8+PD-1+ | Abs_Value | 8 | 8 | 0 | 361.17 | 212.11 | 214.18 - 508.16 | 75.83 - 699.18 | 393.45 | 178.08 - 489.96 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 83.59 | 67.58 | 36.76 - 130.42 | 21.48 - 241.24 | 67 | 48.28 - 87.75 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 277.58 | 166.02 | 162.53 - 392.63 | 29.43 - 457.94 | 313.32 | 127.01 - 423.77 | Н/П* | Н/П* | ||||||||||
8+TIGIT+ | Abs_Value | 8 | 8 | 0 | 604.99 | 480.7 | 271.89 - 938.1 | 36.68 - 1567.95 | 426.9 | 346.35 - 842.55 | Н/П* | Н/П* | ||||||||||
8EMTM | Abs_Value | 8 | 8 | 0 | 157.47 | 116.33 | 76.86 - 238.09 | 20.06 - 335.18 | 141.63 | 55.89 - 238.23 | Н/П* | Н/П* | ||||||||||
8EMTM+226+ | Abs_Value | 8 | 8 | 0 | 134.77 | 98.65 | 66.41 - 203.14 | 17.63 - 283.7 | 122.32 | 48.9 - 208.61 | Н/П* | Н/П* | ||||||||||
8EMTM+39+ | Abs_Value | 8 | 8 | 0 | 23.39 | 19.6 | 9.81 - 36.97 | 0.97 - 52.74 | 23.57 | 4.09 - 39.48 | Н/П* | Н/П* | ||||||||||
8EMTM+DR+ | Abs_Value | 8 | 8 | 0 | 125.15 | 96.78 | 58.09 - 192.22 | 8.01 - 298.35 | 118.77 | 46.34 - 167.33 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 40.68 | 37.73 | 14.54 - 66.83 | 4.5 - 95.71 | 29.93 | 7.39 - 69.84 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 34.07 | 42.71 | 4.47 - 63.67 | 0.84 - 119.96 | 17.86 | 3.85 - 44.74 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+ | Abs_Value | 8 | 8 | 0 | 82.72 | 49.41 | 48.48 - 116.96 | 14.72 - 164.57 | 91.68 | 42.91 - 105.3 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 20.07 | 12.58 | 11.35 - 28.78 | 7.32 - 39.52 | 16.06 | 11.7 - 24.89 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 62.65 | 40.44 | 34.63 - 90.68 | 7.4 - 125.68 | 67.48 | 30.29 - 84.25 | Н/П* | Н/П* | ||||||||||
8EMTM+TIGIT+ | Abs_Value | 8 | 8 | 0 | 96.72 | 74.19 | 45.31 - 148.14 | 8.24 - 220.12 | 86.84 | 34.65 - 150.96 | Н/П* | Н/П* | ||||||||||
8NV | Abs_Value | 8 | 8 | 0 | 58.05 | 57.22 | 18.41 - 97.7 | 8.51 - 189.4 | 38.1 | 29.77 - 65.86 | Н/П* | Н/П* | ||||||||||
8NV(СТАР2) | Abs_Value | 8 | 8 | 0 | 62.09 | 73.13 | 11.41 - 112.77 | 4.23 - 232.76 | 49.11 | 19.27 - 60.6 | Н/П* | Н/П* | ||||||||||
8NV+226+ | Abs_Value | 8 | 8 | 0 | 55.11 | 73.03 | 4.5 - 105.72 | 3.16 - 230.07 | 39.17 | 16.6 - 50.78 | Н/П* | Н/П* | ||||||||||
8NV+39+ | Abs_Value | 8 | 8 | 0 | 4.26 | 5.01 | 0.79 - 7.73 | 0.15 - 12.88 | 2.24 | 0.88 - 5.74 | Н/П* | Н/П* | ||||||||||
8NV+DR+ | Abs_Value | 8 | 8 | 0 | 7.12 | 4.48 | 4.01 - 10.22 | 0.28 - 14.07 | 7.08 | 5.08 - 9.53 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 50.51 | 73.06 | -0.12 - 101.14 | 1.58 - 223.18 | 31.16 | 6.06 - 46.52 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 2.95 | 3.36 | 0.62 - 5.28 | 0.22 - 10.07 | 1.38 | 0.69 - 4.48 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+ | Abs_Value | 8 | 8 | 0 | 8.63 | 6.89 | 3.86 - 13.41 | 0.97 - 19.85 | 5.91 | 4.14 - 14.06 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 4.43 | 5.63 | 0.52 - 8.33 | 0.01 - 14.25 | 1.89 | 0.41 - 6.52 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 4.21 | 3.64 | 1.69 - 6.73 | 0.67 - 11.23 | 3.44 | 1.25 - 5.95 | Н/П* | Н/П* | ||||||||||
8NV+TIGIT+ | Abs_Value | 8 | 8 | 0 | 7.16 | 5.53 | 3.32 - 10.99 | 0.89 - 17.04 | 6.64 | 2.49 - 9.86 | Н/П* | Н/П* | ||||||||||
8TREG | Abs_Value | 8 | 8 | 0 | 545.21 | 535.4 | 174.2 - 916.22 | 63.17 - 1610.29 | 285.52 | 252.25 - 701.11 | Н/П* | Н/П* | ||||||||||
8ЕМ | Abs_Value | 8 | 8 | 0 | 126.1 | 115.45 | 46.1 - 206.11 | 11.85 - 355.83 | 107.95 | 44.1 - 171.12 | Н/П* | Н/П* | ||||||||||
8СМ | Abs_Value | 8 | 8 | 0 | 25.41 | 36.82 | -0.1 - 50.93 | 1.27 - 101.48 | 8.12 | 4.79 - 25.98 | Н/П* | Н/П* | ||||||||||
8СМ(СТАР2) | Abs_Value | 8 | 8 | 0 | 17.73 | 22.04 | 2.46 - 33.01 | 1.08 - 60.65 | 7.6 | 2.54 - 24.44 | Н/П* | Н/П* | ||||||||||
8СМ+226+ | Abs_Value | 8 | 8 | 0 | 12.44 | 16.05 | 1.32 - 23.56 | 0.99 - 48.69 | 6.15 | 2.15 - 15.5 | Н/П* | Н/П* | ||||||||||
8СМ+39+ | Abs_Value | 8 | 8 | 0 | 7.04 | 15.93 | -4 - 18.07 | 0.16 - 46.33 | 1.44 | 0.35 - 3.16 | Н/П* | Н/П* | ||||||||||
8СМ+DR+ | Abs_Value | 8 | 8 | 0 | 14.92 | 19.56 | 1.36 - 28.47 | 0.37 - 51.36 | 5.17 | 2.11 - 20.71 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 1.63 | 1.3 | 0.73 - 2.53 | 0.27 - 3.93 | 1.31 | 0.61 - 2.23 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 2.56 | 3.87 | -0.12 - 5.24 | 0.1 - 10.87 | 0.92 | 0.41 - 2.29 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+ | Abs_Value | 8 | 8 | 0 | 13.54 | 17.72 | 1.26 - 25.82 | 0.32 - 50.7 | 5.37 | 1.99 - 18.71 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 0.83 | 0.89 | 0.21 - 1.45 | 0.07 - 2.5 | 0.39 | 0.3 - 1.15 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 12.71 | 17.22 | 0.78 - 24.64 | 0.25 - 48.83 | 4.73 | 1.69 - 16.73 | Н/П* | Н/П* | ||||||||||
8СМ+TIGIT+ | Abs_Value | 8 | 8 | 0 | 15.27 | 20.33 | 1.19 - 29.36 | 0.38 - 54.85 | 5.65 | 1.91 - 20.23 | Н/П* | Н/П* | ||||||||||
8ТЕ | Abs_Value | 8 | 8 | 0 | 526.81 | 519.95 | 166.5 - 887.11 | 93.48 - 1482.15 | 311.25 | 217.77 - 578.75 | Н/П* | Н/П* | ||||||||||
8ТЕ(СТАР2) | Abs_Value | 8 | 8 | 0 | 758.43 | 674.09 | 291.31 - 1225.55 | 102.52 - 2054.76 | 434.61 | 392.31 - 1019.77 | Н/П* | Н/П* | ||||||||||
8ТЕ+226+ | Abs_Value | 8 | 8 | 0 | 671.96 | 634.86 | 232.03 - 1111.89 | 99.94 - 1884.09 | 365.53 | 285.22 - 895.47 | Н/П* | Н/П* | ||||||||||
8ТЕ+39+ | Abs_Value | 8 | 8 | 0 | 98.34 | 153.1 | -7.75 - 204.43 | 3.31 - 469.2 | 52.07 | 22.93 - 83.65 | Н/П* | Н/П* | ||||||||||
8ТЕ+DR+ | Abs_Value | 8 | 8 | 0 | 476.4 | 443.49 | 169.08 - 783.72 | 22.67 - 1449.4 | 347.41 | 254.15 - 533.69 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT- | Abs_Value | 8 | 8 | 0 | 215.55 | 257.1 | 37.39 - 393.71 | 27.26 - 700.86 | 96.41 | 53.34 - 261.11 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT+ | Abs_Value | 8 | 8 | 0 | 287.16 | 348.87 | 45.41 - 528.92 | 6.1 - 1067.1 | 161.64 | 80.81 - 375.23 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+ | Abs_Value | 8 | 8 | 0 | 255.71 | 174.09 | 135.07 - 376.35 | 56.75 - 510.33 | 280.27 | 73.87 - 389.33 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT- | Abs_Value | 8 | 8 | 0 | 58.3 | 58.42 | 17.81 - 98.78 | 9.24 - 196.26 | 45.46 | 31.28 - 55.95 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT+ | Abs_Value | 8 | 8 | 0 | 197.42 | 137.47 | 102.15 - 292.68 | 20.98 - 357.6 | 223.55 | 55.71 - 318.96 | Н/П* | Н/П* | ||||||||||
8ТЕ+TIGIT+ | Abs_Value | 8 | 8 | 0 | 484.58 | 411.65 | 199.32 - 769.84 | 27.07 - 1300.32 | 334.3 | 235.14 - 721.94 | Н/П* | Н/П* | ||||||||||
8ТМ | Abs_Value | 8 | 8 | 0 | 60.95 | 59.05 | 20.03 - 101.87 | 5.98 - 184.39 | 45.83 | 15.25 - 85.13 | Н/П* | Н/П* | ||||||||||
TREG_CM | Abs_Value | 8 | 8 | 0 | 3.13 | 2.18 | 1.62 - 4.64 | 0.39 - 6.58 | 3.11 | 1.67 - 4.65 | Н/П* | Н/П* | ||||||||||
TREG_EMTM | Abs_Value | 8 | 8 | 0 | 29.53 | 23.85 | 13 - 46.06 | 6.83 - 69.64 | 18.05 | 12.58 - 49.74 | Н/П* | Н/П* | ||||||||||
TREG_NV | Abs_Value | 8 | 8 | 0 | 3.25 | 2.28 | 1.67 - 4.83 | 0.25 - 6.33 | 3.11 | 1.52 - 5.23 | Н/П* | Н/П* | ||||||||||
TREG_TE | Abs_Value | 8 | 8 | 0 | 7.23 | 7.34 | 2.15 - 12.32 | 0.92 - 21.61 | 4.92 | 1.87 - 9.42 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT- | Abs_Value | 8 | 8 | 0 | 3.02 | 2.09 | 1.58 - 4.47 | 0.34 - 6.14 | 2.75 | 1.39 - 4.23 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT+ | Abs_Value | 8 | 8 | 0 | 11.51 | 12.13 | 3.1 - 19.91 | 1.18 - 38.88 | 8.41 | 4.02 - 13.26 | Н/П* | Н/П* | ||||||||||
TREG+226+ | Abs_Value | 8 | 8 | 0 | 28.74 | 20.29 | 14.68 - 42.8 | 7.4 - 58.24 | 20.17 | 14.48 - 43.06 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT- | Abs_Value | 8 | 8 | 0 | 4.69 | 2.41 | 3.02 - 6.36 | 0.65 - 7.21 | 5.74 | 2.69 - 6.14 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT+ | Abs_Value | 8 | 8 | 0 | 24.05 | 18.56 | 11.2 - 36.91 | 6.75 - 51.84 | 16.08 | 10.13 - 36.09 | Н/П* | Н/П* | ||||||||||
TREG+39+ | Abs_Value | 8 | 8 | 0 | 26.13 | 18.4 | 13.38 - 38.88 | 6.67 - 62.29 | 24.03 | 11.41 - 33.36 | Н/П* | Н/П* | ||||||||||
TREG+DR+ | Abs_Value | 8 | 8 | 0 | 30.35 | 28.97 | 10.28 - 50.42 | 4.17 - 87.97 | 17.23 | 11.06 - 44.75 | Н/П* | Н/П* | ||||||||||
TREG+PD-1+ | Abs_Value | 8 | 8 | 0 | 18.73 | 16.12 | 7.57 - 29.9 | 4.48 - 54.08 | 14.55 | 9.46 - 19.64 | Н/П* | Н/П* | ||||||||||
TREG+TIGIT+ | Abs_Value | 8 | 8 | 0 | 35.56 | 28.98 | 15.48 - 55.65 | 7.94 - 89.91 | 23.42 | 15.76 - 51.2 | Н/П* | Н/П* | ||||||||||
ДЕНЬ ХРРТПХ +30 | 4_TFH | Abs_Value | 15 | 15 | 0 | 41.42 | 35.22 | 23.59 - 59.25 | 1.88 - 144.19 | 34.77 | 19.59 - 48.2 | Н/П* | Н/П* | |||||||||
4_TH1 | Abs_Value | 15 | 15 | 0 | 18.7 | 11.35 | 12.96 - 24.44 | 0.66 - 34.4 | 17.15 | 9.34 - 28.6 | Н/П* | Н/П* | ||||||||||
4_TH17 | Abs_Value | 15 | 15 | 0 | 27.05 | 22.76 | 15.53 - 38.57 | 3.09 - 89.01 | 29.2 | 9.12 - 34.98 | Н/П* | Н/П* | ||||||||||
4_Th17TO1 | Abs_Value | 15 | 15 | 0 | 5.5 | 5 | 2.97 - 8.03 | 0.12 - 17.42 | 3.34 | 2.54 - 6.4 | Н/П* | Н/П* | ||||||||||
4_TH2 | Abs_Value | 15 | 15 | 0 | 32.35 | 34.88 | 14.7 - 50 | 2.05 - 117.68 | 19.15 | 12.1 - 29.88 | Н/П* | Н/П* | ||||||||||
4_TH22 | Abs_Value | 15 | 15 | 0 | 10.2 | 8.13 | 6.09 - 14.32 | 0.28 - 25.4 | 8.22 | 4.08 - 16.88 | Н/П* | Н/П* | ||||||||||
4+ | Abs_Value | 15 | 15 | 0 | 113.45 | 77.06 | 74.45 - 152.44 | 12.27 - 279.76 | 115.34 | 52.55 - 137.07 | Н/П* | Н/П* | ||||||||||
4+ (IM STAT) | Abs_Value | 15 | 15 | 0 | 83.06 | 47.94 | 58.8 - 107.32 | 4.93 - 174.05 | 94.04 | 49.17 - 113.02 | Н/П* | Н/П* | ||||||||||
4+226+ | Abs_Value | 15 | 15 | 0 | 258.58 | 149.29 | 183.03 - 334.13 | 16.9 - 520.8 | 261.93 | 133.57 - 367.46 | Н/П* | Н/П* | ||||||||||
4+39+ | Abs_Value | 15 | 15 | 0 | 60.66 | 49.31 | 35.7 - 85.61 | 7.34 - 160.47 | 51.07 | 18.09 - 98.84 | Н/П* | Н/П* | ||||||||||
4+DR+ | Abs_Value | 15 | 15 | 0 | 84.97 | 62.79 | 53.19 - 116.74 | 9.79 - 265.5 | 83.23 | 48.31 - 108.22 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 126.96 | 82.73 | 85.1 - 168.83 | 5.65 - 256.76 | 136.66 | 45.58 - 192.53 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 9.1 | 6.8 | 5.66 - 12.55 | 0.42 - 23.61 | 6.58 | 4.12 - 14.19 | Н/П* | Н/П* | ||||||||||
4+PD-1+ | Abs_Value | 15 | 15 | 0 | 141.17 | 92.6 | 94.31 - 188.03 | 11.98 - 315.97 | 130.18 | 76.11 - 198.25 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 75.02 | 49.16 | 50.14 - 99.89 | 7.35 - 183.9 | 75.16 | 37.11 - 95.98 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 66.15 | 46.61 | 42.57 - 89.74 | 4.63 - 152.42 | 45.69 | 36.49 - 103.46 | Н/П* | Н/П* | ||||||||||
4+TIGIT+ | Abs_Value | 15 | 15 | 0 | 75.26 | 51.98 | 48.95 - 101.56 | 5.05 - 169.73 | 56.34 | 40.61 - 112.97 | Н/П* | Н/П* | ||||||||||
4NV | Abs_Value | 15 | 15 | 0 | 68.83 | 57.06 | 39.95 - 97.71 | 4.02 - 183.37 | 52.65 | 22.6 - 99.81 | Н/П* | Н/П* | ||||||||||
4NV(СТАР2) | Abs_Value | 15 | 15 | 0 | 61.97 | 55.34 | 33.97 - 89.98 | 3.41 - 181.45 | 44.3 | 19.68 - 93.27 | Н/П* | Н/П* | ||||||||||
4NV_TH1 | Abs_Value | 15 | 15 | 0 | 3.96 | 3.53 | 2.18 - 5.75 | 0.17 - 10.34 | 2.83 | 0.67 - 6.5 | Н/П* | Н/П* | ||||||||||
4NV_TH17 | Abs_Value | 15 | 15 | 0 | 2.14 | 1.92 | 1.17 - 3.11 | 0.28 - 6.27 | 1.46 | 0.75 - 2.59 | Н/П* | Н/П* | ||||||||||
4NV_Th17TO1 | Abs_Value | 15 | 15 | 0 | 0.38 | 0.41 | 0.17 - 0.59 | 0.01 - 1.64 | 0.31 | 0.08 - 0.53 | Н/П* | Н/П* | ||||||||||
4NV_TH2 | Abs_Value | 15 | 15 | 0 | 7.94 | 7.05 | 4.37 - 11.51 | 0.44 - 23.62 | 5.43 | 1.83 - 14.44 | Н/П* | Н/П* | ||||||||||
4NV_TH22 | Abs_Value | 15 | 15 | 0 | 0.12 | 0.14 | 0.05 - 0.19 | 0 - 0.49 | 0.09 | 0.02 - 0.14 | Н/П* | Н/П* | ||||||||||
4NV+226+ | Abs_Value | 15 | 15 | 0 | 55.53 | 50.79 | 29.83 - 81.23 | 3.06 - 175.11 | 39.74 | 17.39 - 84.16 | Н/П* | Н/П* | ||||||||||
4NV+39+ | Abs_Value | 15 | 15 | 0 | 1.75 | 2.76 | 0.35 - 3.14 | 0.01 - 11.3 | 1.08 | 0.37 - 1.7 | Н/П* | Н/П* | ||||||||||
4NV+DR+ | Abs_Value | 15 | 15 | 0 | 3.23 | 3.9 | 1.26 - 5.2 | 0.15 - 13.12 | 1.81 | 1.05 - 2.84 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 58.02 | 53.13 | 31.13 - 84.9 | 2.88 - 176.14 | 41.17 | 17.05 - 88.71 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 1.07 | 1.18 | 0.47 - 1.66 | 0.08 - 4.15 | 0.68 | 0.23 - 1.59 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 2.03 | 2.76 | 0.64 - 3.43 | 0.09 - 11.35 | 1.28 | 0.72 - 2.04 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 0.86 | 0.73 | 0.49 - 1.22 | 0.08 - 2.32 | 0.66 | 0.43 - 1.16 | Н/П* | Н/П* | ||||||||||
4NV+PD1+ | Abs_Value | 15 | 15 | 0 | 2.89 | 3.29 | 1.22 - 4.56 | 0.17 - 13.68 | 1.81 | 1.35 - 3.46 | Н/П* | Н/П* | ||||||||||
4NV+TIGIT+ | Abs_Value | 15 | 15 | 0 | 1.92 | 1.87 | 0.98 - 2.87 | 0.16 - 6.48 | 1.36 | 0.74 - 2.73 | Н/П* | Н/П* | ||||||||||
4ЕМ | Abs_Value | 15 | 15 | 0 | 8.01 | 9.16 | 3.37 - 12.65 | 0.03 - 29.57 | 3.27 | 2.21 - 14.05 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH1 | Abs_Value | 15 | 15 | 0 | 1.58 | 1.93 | 0.6 - 2.55 | 0.01 - 6.46 | 1.04 | 0.52 - 1.68 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH17 | Abs_Value | 15 | 15 | 0 | 0.14 | 0.47 | -0.1 - 0.38 | 0 - 1.83 | 0 | 0 - 0.03 | Н/П* | Н/П* | ||||||||||
4ЕМ_Th17TO1 | Abs_Value | 15 | 15 | 0 | 0.09 | 0.13 | 0.02 - 0.16 | 0 - 0.54 | 0.06 | 0.01 - 0.09 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH2 | Abs_Value | 15 | 15 | 0 | 1.2 | 3.96 | -0.8 - 3.2 | 0.01 - 15.48 | 0.08 | 0.04 - 0.29 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH22 | Abs_Value | 15 | 15 | 0 | 0 | 0.01 | 0 - 0.01 | 0 - 0.02 | 0 | 0 - 0 | Н/П* | Н/П* | ||||||||||
4ЕМ+226+ | Abs_Value | 15 | 15 | 0 | 117.34 | 79.32 | 77.19 - 157.48 | 6.84 - 253.96 | 92.56 | 50.54 - 178.57 | Н/П* | Н/П* | ||||||||||
4ЕМ+39+ | Abs_Value | 15 | 15 | 0 | 37.54 | 33.1 | 20.79 - 54.29 | 4.45 - 111.55 | 28.6 | 11.75 - 57.97 | Н/П* | Н/П* | ||||||||||
4ЕМ+DR+ | Abs_Value | 15 | 15 | 0 | 57.12 | 45.75 | 33.97 - 80.27 | 4.57 - 188.94 | 47.84 | 28.28 - 73.33 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT- | Abs_Value | 15 | 15 | 0 | 32.35 | 27.25 | 18.56 - 46.13 | 0.6 - 91.12 | 36.85 | 8.89 - 47.51 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 3.44 | 2.85 | 2 - 4.88 | 0.08 - 9.64 | 2.2 | 1.27 - 5.62 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+ | Abs_Value | 15 | 15 | 0 | 87.7 | 57.65 | 58.53 - 116.87 | 6.41 - 195.8 | 79.37 | 42.57 - 133.07 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT- | Abs_Value | 15 | 15 | 0 | 48.54 | 31.01 | 32.84 - 64.23 | 4.01 - 115.09 | 45.93 | 23.82 - 71.85 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 39.16 | 28.54 | 24.72 - 53.61 | 2.39 - 80.71 | 28.76 | 15.72 - 70.77 | Н/П* | Н/П* | ||||||||||
4ЕМ+TIGIT+ | Abs_Value | 15 | 15 | 0 | 42.6 | 30.6 | 27.12 - 58.09 | 2.47 - 88.33 | 29.75 | 17.11 - 74.95 | Н/П* | Н/П* | ||||||||||
4ЕМTM | Abs_Value | 15 | 15 | 0 | 123.49 | 83.06 | 81.45 - 165.52 | 7.08 - 263.87 | 97.56 | 55.67 - 186.59 | Н/П* | Н/П* | ||||||||||
4СМ | Abs_Value | 15 | 15 | 0 | 72.69 | 52.49 | 46.12 - 99.25 | 6.84 - 182.94 | 64.37 | 31.44 - 103.84 | Н/П* | Н/П* | ||||||||||
4СМ(СТАР2) | Abs_Value | 15 | 15 | 0 | 59.44 | 43.19 | 37.59 - 81.3 | 3.79 - 156.19 | 53.43 | 30.31 - 83.44 | Н/П* | Н/П* | ||||||||||
4СМ_TH1 | Abs_Value | 15 | 15 | 0 | 2.57 | 2.12 | 1.5 - 3.64 | 0.18 - 6.72 | 2.27 | 0.7 - 3.4 | Н/П* | Н/П* | ||||||||||
4СМ_TH17 | Abs_Value | 15 | 15 | 0 | 10.25 | 7.2 | 6.61 - 13.89 | 1.53 - 20.35 | 10.12 | 3.42 - 16.88 | Н/П* | Н/П* | ||||||||||
4СМ_Th17TO1 | Abs_Value | 15 | 15 | 0 | 1.09 | 1.3 | 0.44 - 1.75 | 0.04 - 4.95 | 0.57 | 0.5 - 1.03 | Н/П* | Н/П* | ||||||||||
4СМ_TH2 | Abs_Value | 15 | 15 | 0 | 7.94 | 10.63 | 2.56 - 13.32 | 0.53 - 43.16 | 5.73 | 1.69 - 8.08 | Н/П* | Н/П* | ||||||||||
4СМ_TH22 | Abs_Value | 15 | 15 | 0 | 1.21 | 1.35 | 0.52 - 1.89 | 0.09 - 5.05 | 0.66 | 0.21 - 1.6 | Н/П* | Н/П* | ||||||||||
4СМ+226+ | Abs_Value | 15 | 15 | 0 | 56.63 | 41.5 | 35.63 - 77.64 | 3.54 - 150.99 | 51.16 | 28.19 - 79.37 | Н/П* | Н/П* | ||||||||||
4СМ+39+ | Abs_Value | 15 | 15 | 0 | 16.23 | 16.63 | 7.81 - 24.65 | 0.32 - 63.2 | 15.74 | 4.09 - 21.21 | Н/П* | Н/П* | ||||||||||
4СМ+DR+ | Abs_Value | 15 | 15 | 0 | 11.87 | 9.36 | 7.13 - 16.61 | 0.74 - 30.47 | 11.86 | 4.41 - 16.27 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT- | Abs_Value | 15 | 15 | 0 | 23.04 | 16.45 | 14.71 - 31.36 | 0.98 - 52.58 | 23.91 | 7.34 - 33.86 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 2.64 | 2.07 | 1.59 - 3.69 | 0.1 - 6.56 | 2.19 | 0.98 - 3.81 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+ | Abs_Value | 15 | 15 | 0 | 33.77 | 29.24 | 18.97 - 48.57 | 2.28 - 112.1 | 25.79 | 15.5 - 40.13 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT- | Abs_Value | 15 | 15 | 0 | 14.41 | 12.54 | 8.06 - 20.76 | 1.16 - 43.45 | 10.48 | 6.3 - 19.55 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 19.36 | 17.82 | 10.34 - 28.38 | 1.13 - 68.65 | 14.97 | 9.62 - 21.95 | Н/П* | Н/П* | ||||||||||
4СМ+TIGIT+ | Abs_Value | 15 | 15 | 0 | 22 | 19.34 | 12.21 - 31.79 | 1.33 - 75.21 | 16.36 | 13.43 - 24.87 | Н/П* | Н/П* | ||||||||||
4ТM_TH1 | Abs_Value | 15 | 15 | 0 | 6.89 | 5.17 | 4.28 - 9.51 | 0.2 - 15.48 | 5.33 | 3.2 - 10.96 | Н/П* | Н/П* | ||||||||||
4ТM_TH17 | Abs_Value | 15 | 15 | 0 | 13.31 | 15.17 | 5.64 - 20.99 | 0.71 - 55.73 | 10.63 | 3.85 - 13.15 | Н/П* | Н/П* | ||||||||||
4ТM_Th17TO1 | Abs_Value | 15 | 15 | 0 | 3.4 | 3.05 | 1.85 - 4.94 | 0.05 - 9.26 | 2.18 | 1.5 - 4.78 | Н/П* | Н/П* | ||||||||||
4ТM_TH2 | Abs_Value | 15 | 15 | 0 | 13.23 | 22.12 | 2.04 - 24.43 | 0.25 - 77.73 | 3.24 | 1.25 - 10.52 | Н/П* | Н/П* | ||||||||||
4ТM_TH22 | Abs_Value | 15 | 15 | 0 | 7.99 | 7.02 | 4.43 - 11.54 | 0.09 - 23.06 | 5.64 | 2.71 - 13.79 | Н/П* | Н/П* | ||||||||||
4ТREG | Abs_Value | 15 | 15 | 0 | 4.6 | 4.45 | 2.35 - 6.85 | 0.4 - 16.67 | 3.82 | 1.9 - 5.07 | Н/П* | Н/П* | ||||||||||
4ТREG(СТАР2) | Abs_Value | 15 | 15 | 0 | 115.61 | 78.89 | 75.68 - 155.53 | 12.1 - 286.85 | 117.64 | 52.03 - 141.84 | Н/П* | Н/П* | ||||||||||
4ТREG_TH1 | Abs_Value | 15 | 15 | 0 | 0.29 | 0.22 | 0.17 - 0.4 | 0.01 - 0.75 | 0.25 | 0.11 - 0.48 | Н/П* | Н/П* | ||||||||||
4ТREG_TH17 | Abs_Value | 15 | 15 | 0 | 7.04 | 7.91 | 3.04 - 11.05 | 0.53 - 24.8 | 3.6 | 2.5 - 6.65 | Н/П* | Н/П* | ||||||||||
4ТREG_Th17TO1 | Abs_Value | 15 | 15 | 0 | 0.1 | 0.11 | 0.05 - 0.15 | 0 - 0.34 | 0.06 | 0.02 - 0.16 | Н/П* | Н/П* | ||||||||||
4ТREG_TH2 | Abs_Value | 15 | 15 | 0 | 4.32 | 5.41 | 1.59 - 7.06 | 0.18 - 18.49 | 2.52 | 1.77 - 3.33 | Н/П* | Н/П* | ||||||||||
4ТREG_TH22 | Abs_Value | 15 | 15 | 0 | 6.24 | 5.63 | 3.39 - 9.09 | 0.48 - 19.57 | 5 | 1.79 - 7.33 | Н/П* | Н/П* | ||||||||||
4ТЕ | Abs_Value | 15 | 15 | 0 | 5.88 | 8.77 | 1.44 - 10.32 | 0.02 - 33.66 | 3.33 | 0.28 - 7.82 | Н/П* | Н/П* | ||||||||||
4ТЕ(СТАР2) | Abs_Value | 15 | 15 | 0 | 31.57 | 20.83 | 21.03 - 42.11 | 3.14 - 68.2 | 27.41 | 20.69 - 43.27 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH1 | Abs_Value | 15 | 15 | 0 | 1.51 | 2.07 | 0.47 - 2.56 | 0.01 - 6.53 | 0.37 | 0.06 - 2.29 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH17 | Abs_Value | 15 | 15 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.1 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ_Th17TO1 | Abs_Value | 15 | 15 | 0 | 0.05 | 0.08 | 0.01 - 0.1 | 0 - 0.26 | 0.01 | 0 - 0.08 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH2 | Abs_Value | 15 | 15 | 0 | 0.14 | 0.18 | 0.05 - 0.23 | 0 - 0.61 | 0.07 | 0 - 0.23 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH22 | Abs_Value | 15 | 15 | 0 | 0.01 | 0.02 | 0 - 0.02 | 0 - 0.06 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ+226+ | Abs_Value | 15 | 15 | 0 | 28.47 | 18.77 | 18.97 - 37.97 | 2.9 - 61.52 | 24.82 | 18.55 - 41 | Н/П* | Н/П* | ||||||||||
4ТЕ+39+ | Abs_Value | 15 | 15 | 0 | 5.25 | 3.92 | 3.26 - 7.23 | 0.69 - 13.77 | 4.75 | 1.81 - 7.46 | Н/П* | Н/П* | ||||||||||
4ТЕ+DR+ | Abs_Value | 15 | 15 | 0 | 12.88 | 9.8 | 7.92 - 17.84 | 0.58 - 35.94 | 11.91 | 4.58 - 18.14 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 12.52 | 10.11 | 7.4 - 17.63 | 0.87 - 37.08 | 10.68 | 7.43 - 14.06 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 1.89 | 1.74 | 1.01 - 2.77 | 0.07 - 7.04 | 1.41 | 0.78 - 2.42 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+ | Abs_Value | 15 | 15 | 0 | 17.17 | 12.94 | 10.62 - 23.72 | 1.5 - 42.91 | 15.16 | 8.07 - 20.76 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 10.15 | 8.57 | 5.81 - 14.49 | 0.74 - 31.83 | 7.39 | 4 - 15.3 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 7.01 | 5.67 | 4.14 - 9.88 | 0.76 - 22.71 | 6.36 | 4.24 - 7.37 | Н/П* | Н/П* | ||||||||||
4ТЕ+TIGIT+ | Abs_Value | 15 | 15 | 0 | 8.9 | 7.28 | 5.22 - 12.59 | 0.88 - 29.75 | 7.6 | 5.02 - 10.38 | Н/П* | Н/П* | ||||||||||
4ТМ | Abs_Value | 15 | 15 | 0 | 110.74 | 77.46 | 71.54 - 149.94 | 5 - 226.12 | 88.73 | 45.16 - 173.91 | Н/П* | Н/П* | ||||||||||
8+ | Abs_Value | 15 | 15 | 0 | 454.96 | 301.52 | 302.37 - 607.55 | 23.55 - 922.88 | 549.84 | 163.75 - 673.27 | Н/П* | Н/П* | ||||||||||
8+ (IM STAT) | Abs_Value | 15 | 15 | 0 | 585.72 | 390.28 | 388.21 - 783.23 | 24.94 - 1331.74 | 688.88 | 220.35 - 851.78 | Н/П* | Н/П* | ||||||||||
8+226+ | Abs_Value | 15 | 15 | 0 | 735.7 | 486.29 | 489.6 - 981.79 | 38.86 - 1789.01 | 825.43 | 303.22 - 983.5 | Н/П* | Н/П* | ||||||||||
8+39+ | Abs_Value | 15 | 15 | 0 | 114.39 | 114.56 | 56.41 - 172.36 | 16.66 - 357.72 | 41.29 | 24.39 - 183.7 | Н/П* | Н/П* | ||||||||||
8+DR+ | Abs_Value | 15 | 15 | 0 | 575.11 | 408.95 | 368.15 - 782.06 | 42.24 - 1466.62 | 593.7 | 229.91 - 684.66 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 251.97 | 184.25 | 158.73 - 345.21 | 11.27 - 622.7 | 261.4 | 86.93 - 385.69 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 242.39 | 172.19 | 155.25 - 329.53 | 8.34 - 526.18 | 205.45 | 92.47 - 382.59 | Н/П* | Н/П* | ||||||||||
8+PD-1+ | Abs_Value | 15 | 15 | 0 | 354.74 | 310.4 | 197.66 - 511.83 | 17.27 - 1087.66 | 309.38 | 134.94 - 539.92 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 123.02 | 146.03 | 49.11 - 196.92 | 2.82 - 534.79 | 60.17 | 29.02 - 171.1 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 231.73 | 193.18 | 133.96 - 329.49 | 14.46 - 610.79 | 129.1 | 105.33 - 354.03 | Н/П* | Н/П* | ||||||||||
8+TIGIT+ | Abs_Value | 15 | 15 | 0 | 474.11 | 307.19 | 318.66 - 629.57 | 37.05 - 948.67 | 494.17 | 217.71 - 739.83 | Н/П* | Н/П* | ||||||||||
8EMTM | Abs_Value | 15 | 15 | 0 | 129.44 | 92.83 | 82.46 - 176.42 | 1.08 - 323.39 | 126.6 | 59.22 - 174.2 | Н/П* | Н/П* | ||||||||||
8EMTM+226+ | Abs_Value | 15 | 15 | 0 | 102.37 | 66.2 | 68.87 - 135.87 | 0.93 - 235.61 | 114.55 | 49.95 - 145.93 | Н/П* | Н/П* | ||||||||||
8EMTM+39+ | Abs_Value | 15 | 15 | 0 | 27.9 | 31.46 | 11.98 - 43.82 | 0.67 - 104.21 | 14.41 | 5.84 - 41.03 | Н/П* | Н/П* | ||||||||||
8EMTM+DR+ | Abs_Value | 15 | 15 | 0 | 104.25 | 73.16 | 67.22 - 141.27 | 0.9 - 274.76 | 100.99 | 55.05 - 136.05 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 23.96 | 15.74 | 15.99 - 31.93 | 0.14 - 48.43 | 28.99 | 10.71 - 32.49 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 27.07 | 30.9 | 11.43 - 42.71 | 0.05 - 97 | 13.96 | 6.64 - 40.15 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+ | Abs_Value | 15 | 15 | 0 | 78.41 | 59.13 | 48.49 - 108.34 | 0.88 - 195.42 | 71.52 | 43.76 - 92.46 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 23.48 | 20.37 | 13.17 - 33.79 | 0.31 - 69.43 | 19.83 | 6.65 - 34.68 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 54.93 | 47.52 | 30.88 - 78.98 | 0.58 - 163.69 | 42.61 | 29.39 - 68.04 | Н/П* | Н/П* | ||||||||||
8EMTM+TIGIT+ | Abs_Value | 15 | 15 | 0 | 82 | 74.15 | 44.47 - 119.53 | 0.63 - 226.09 | 54.58 | 32.91 - 131.91 | Н/П* | Н/П* | ||||||||||
8NV | Abs_Value | 15 | 15 | 0 | 32.09 | 27.63 | 18.11 - 46.08 | 4.86 - 82.24 | 20.92 | 9.56 - 48.01 | Н/П* | Н/П* | ||||||||||
8NV(СТАР2) | Abs_Value | 15 | 15 | 0 | 34.3 | 28.76 | 19.74 - 48.85 | 2.72 - 93.55 | 24.99 | 6.57 - 58.3 | Н/П* | Н/П* | ||||||||||
8NV+226+ | Abs_Value | 15 | 15 | 0 | 29.83 | 25.73 | 16.8 - 42.85 | 2.36 - 87.03 | 24.46 | 5.45 - 49.76 | Н/П* | Н/П* | ||||||||||
8NV+39+ | Abs_Value | 15 | 15 | 0 | 3.41 | 4.89 | 0.93 - 5.88 | 0 - 17.8 | 1.14 | 0.37 - 4.4 | Н/П* | Н/П* | ||||||||||
8NV+DR+ | Abs_Value | 15 | 15 | 0 | 5.06 | 6 | 2.02 - 8.09 | 0.27 - 21.82 | 2.96 | 1.32 - 5.7 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 27.14 | 26.38 | 13.79 - 40.49 | 0.86 - 90.53 | 19.82 | 5.58 - 46.88 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 2.26 | 2.32 | 1.08 - 3.43 | 0.19 - 8.04 | 1.63 | 0.54 - 3.45 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+ | Abs_Value | 15 | 15 | 0 | 4.9 | 7.29 | 1.21 - 8.59 | 0.09 - 25.44 | 1.31 | 0.74 - 5.67 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 1.18 | 1.9 | 0.22 - 2.14 | 0.01 - 6.86 | 0.32 | 0.09 - 1.31 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 3.71 | 5.8 | 0.78 - 6.65 | 0.08 - 21.78 | 1.01 | 0.62 - 4.05 | Н/П* | Н/П* | ||||||||||
8NV+TIGIT+ | Abs_Value | 15 | 15 | 0 | 5.97 | 6.65 | 2.61 - 9.34 | 0.35 - 25.67 | 3.22 | 1.54 - 8.12 | Н/П* | Н/П* | ||||||||||
8TREG | Abs_Value | 15 | 15 | 0 | 445.89 | 292.69 | 297.77 - 594.01 | 20.46 - 892.2 | 544.62 | 162.87 - 665.11 | Н/П* | Н/П* | ||||||||||
8ЕМ | Abs_Value | 15 | 15 | 0 | 92.33 | 61.79 | 61.06 - 123.6 | 0.5 - 229.56 | 93.55 | 43.05 - 128.36 | Н/П* | Н/П* | ||||||||||
8СМ | Abs_Value | 15 | 15 | 0 | 21.45 | 27.26 | 7.65 - 35.24 | 0.61 - 77.79 | 8.32 | 4.62 - 24.69 | Н/П* | Н/П* | ||||||||||
8СМ(СТАР2) | Abs_Value | 15 | 15 | 0 | 18.25 | 24.46 | 5.87 - 30.62 | 0.4 - 85.81 | 7.24 | 2.61 - 25.28 | Н/П* | Н/П* | ||||||||||
8СМ+226+ | Abs_Value | 15 | 15 | 0 | 12.81 | 17.04 | 4.18 - 21.43 | 0.36 - 60.98 | 6.43 | 2.05 - 15.28 | Н/П* | Н/П* | ||||||||||
8СМ+39+ | Abs_Value | 15 | 15 | 0 | 6.38 | 10.39 | 1.12 - 11.64 | 0.12 - 32.91 | 1.15 | 0.4 - 6.79 | Н/П* | Н/П* | ||||||||||
8СМ+DR+ | Abs_Value | 15 | 15 | 0 | 14.68 | 19.65 | 4.74 - 24.63 | 0.17 - 63.4 | 4.51 | 2.17 - 22.39 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 2.85 | 3.95 | 0.85 - 4.85 | 0.03 - 15.83 | 1.77 | 0.64 - 2.93 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 3.4 | 4.78 | 0.99 - 5.82 | 0.07 - 18.1 | 1.05 | 0.32 - 5.38 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+ | Abs_Value | 15 | 15 | 0 | 11.99 | 16.71 | 3.53 - 20.45 | 0.15 - 51.89 | 4 | 1.51 - 15.08 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 1.24 | 1.7 | 0.38 - 2.1 | 0.02 - 6.29 | 0.57 | 0.13 - 1.91 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 10.75 | 15.28 | 3.02 - 18.49 | 0.12 - 48.73 | 2.14 | 1.38 - 13.8 | Н/П* | Н/П* | ||||||||||
8СМ+TIGIT+ | Abs_Value | 15 | 15 | 0 | 14.16 | 19.6 | 4.24 - 24.08 | 0.2 - 66.83 | 4.86 | 2.03 - 20.16 | Н/П* | Н/П* | ||||||||||
8ТЕ | Abs_Value | 15 | 15 | 0 | 481.07 | 361.97 | 297.88 - 664.25 | 6.43 - 1353.64 | 461.4 | 190.67 - 655.26 | Н/П* | Н/П* | ||||||||||
8ТЕ(СТАР2) | Abs_Value | 15 | 15 | 0 | 664.73 | 461.52 | 431.16 - 898.29 | 56.16 - 1732.27 | 718.48 | 241.65 - 862.68 | Н/П* | Н/П* | ||||||||||
8ТЕ+226+ | Abs_Value | 15 | 15 | 0 | 588.82 | 441.14 | 365.57 - 812.07 | 33.24 - 1657.11 | 649.69 | 210.33 - 738.66 | Н/П* | Н/П* | ||||||||||
8ТЕ+39+ | Abs_Value | 15 | 15 | 0 | 76.43 | 77.61 | 37.16 - 115.71 | 12.62 - 275.32 | 36.22 | 15.97 - 128.88 | Н/П* | Н/П* | ||||||||||
8ТЕ+DR+ | Abs_Value | 15 | 15 | 0 | 450.51 | 368.94 | 263.8 - 637.22 | 39.8 - 1367.91 | 434.18 | 172.47 - 533.54 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT- | Abs_Value | 15 | 15 | 0 | 197.21 | 165.31 | 113.55 - 280.86 | 7.02 - 566.21 | 180.62 | 47.02 - 306.88 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT+ | Abs_Value | 15 | 15 | 0 | 208.78 | 145.39 | 135.2 - 282.36 | 7.47 - 439.67 | 188.42 | 79.03 - 308.92 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+ | Abs_Value | 15 | 15 | 0 | 258.74 | 270.88 | 121.66 - 395.82 | 15.97 - 1004.7 | 215.94 | 72.21 - 321.98 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT- | Abs_Value | 15 | 15 | 0 | 97.06 | 132.41 | 30.05 - 164.06 | 2.47 - 498.86 | 43.16 | 15.49 - 123.69 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT+ | Abs_Value | 15 | 15 | 0 | 161.68 | 155.73 | 82.87 - 240.5 | 13.5 - 505.84 | 83.47 | 58.05 - 198.7 | Н/П* | Н/П* | ||||||||||
8ТЕ+TIGIT+ | Abs_Value | 15 | 15 | 0 | 370.46 | 242.29 | 247.85 - 493.08 | 30.75 - 687.19 | 449 | 158.04 - 566.74 | Н/П* | Н/П* | ||||||||||
8ТМ | Abs_Value | 15 | 15 | 0 | 59.34 | 51.96 | 33.04 - 85.64 | 1.32 - 166.73 | 42.86 | 21.57 - 82.19 | Н/П* | Н/П* | ||||||||||
TREG_CM | Abs_Value | 15 | 15 | 0 | 2.08 | 1.6 | 1.27 - 2.89 | 0.16 - 5.88 | 1.61 | 0.95 - 3.23 | Н/П* | Н/П* | ||||||||||
TREG_EMTM | Abs_Value | 15 | 15 | 0 | 29.34 | 25.6 | 16.39 - 42.3 | 1.8 - 84.82 | 25.51 | 11.82 - 34.09 | Н/П* | Н/П* | ||||||||||
TREG_NV | Abs_Value | 15 | 15 | 0 | 1.88 | 1.65 | 1.04 - 2.71 | 0.08 - 4.93 | 1.29 | 0.54 - 3.14 | Н/П* | Н/П* | ||||||||||
TREG_TE | Abs_Value | 15 | 15 | 0 | 4.65 | 3.51 | 2.87 - 6.42 | 0.61 - 11.35 | 3.75 | 2.05 - 5.65 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT- | Abs_Value | 15 | 15 | 0 | 1.81 | 1.59 | 1 - 2.62 | 0.1 - 5.34 | 1.12 | 1.01 - 2.25 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT+ | Abs_Value | 15 | 15 | 0 | 7.69 | 6.68 | 4.31 - 11.07 | 0.59 - 26.4 | 5.69 | 3.99 - 11.05 | Н/П* | Н/П* | ||||||||||
TREG+226+ | Abs_Value | 15 | 15 | 0 | 28.52 | 23.47 | 16.64 - 40.4 | 2.17 - 75.68 | 24.5 | 13.63 - 29.7 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT- | Abs_Value | 15 | 15 | 0 | 2.89 | 1.74 | 2.01 - 3.77 | 0.17 - 7.07 | 3.06 | 1.71 - 3.51 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT+ | Abs_Value | 15 | 15 | 0 | 25.63 | 22.38 | 14.3 - 36.96 | 2 - 69.16 | 21.31 | 10.97 - 26.56 | Н/П* | Н/П* | ||||||||||
TREG+39+ | Abs_Value | 15 | 15 | 0 | 25.07 | 18.82 | 15.55 - 34.6 | 2.7 - 79.85 | 18.08 | 15.1 - 30.32 | Н/П* | Н/П* | ||||||||||
TREG+DR+ | Abs_Value | 15 | 15 | 0 | 29.17 | 24.94 | 16.55 - 41.79 | 2.49 - 88.09 | 23.93 | 13.72 - 33.11 | Н/П* | Н/П* | ||||||||||
TREG+PD-1+ | Abs_Value | 15 | 15 | 0 | 18.76 | 20.3 | 8.49 - 29.03 | 1.91 - 63.74 | 7.76 | 5.51 - 20.16 | Н/П* | Н/П* | ||||||||||
TREG+TIGIT+ | Abs_Value | 15 | 15 | 0 | 33.32 | 27.8 | 19.25 - 47.39 | 2.59 - 95.01 | 29.17 | 14.94 - 37.72 | Н/П* | Н/П* | ||||||||||
ДЕНЬ ХРРТПХ +60 | 4_TFH | Abs_Value | 11 | 11 | 0 | 28.68 | 15.62 | 19.45 - 37.91 | 3.33 - 54.11 | 28.46 | 19.56 - 37.1 | Н/П* | Н/П* | |||||||||
4_TH1 | Abs_Value | 11 | 11 | 0 | 35.88 | 30.33 | 17.95 - 53.81 | 4.85 - 102.42 | 24.35 | 17.37 - 50.66 | Н/П* | Н/П* | ||||||||||
4_TH17 | Abs_Value | 11 | 11 | 0 | 16.99 | 8.94 | 11.71 - 22.27 | 5.06 - 31.95 | 14.47 | 11.07 - 22.14 | Н/П* | Н/П* | ||||||||||
4_Th17TO1 | Abs_Value | 11 | 11 | 0 | 5.93 | 3.78 | 3.7 - 8.16 | 0.57 - 14.51 | 5.47 | 3.56 - 8.08 | Н/П* | Н/П* | ||||||||||
4_TH2 | Abs_Value | 11 | 11 | 0 | 23.51 | 26.51 | 7.84 - 39.18 | 3.06 - 91.26 | 12.68 | 8.27 - 24.48 | Н/П* | Н/П* | ||||||||||
4_TH22 | Abs_Value | 11 | 11 | 0 | 7.43 | 7.7 | 2.87 - 11.98 | 0.89 - 23.85 | 4.44 | 1.81 - 8.44 | Н/П* | Н/П* | ||||||||||
4+ | Abs_Value | 11 | 11 | 0 | 143.45 | 110.14 | 78.36 - 208.54 | 18.83 - 343.47 | 103.46 | 76.62 - 181.02 | Н/П* | Н/П* | ||||||||||
4+ (IM STAT) | Abs_Value | 11 | 11 | 0 | 107.12 | 91.74 | 52.91 - 161.34 | 9 - 338.01 | 96.04 | 49.64 - 120.74 | Н/П* | Н/П* | ||||||||||
4+226+ | Abs_Value | 11 | 11 | 0 | 295.97 | 201.02 | 177.18 - 414.77 | 52.17 - 682.45 | 246.62 | 161.27 - 388.47 | Н/П* | Н/П* | ||||||||||
4+39+ | Abs_Value | 11 | 11 | 0 | 56.6 | 45.2 | 29.89 - 83.31 | 4.61 - 145.64 | 66.4 | 16.69 - 76.04 | Н/П* | Н/П* | ||||||||||
4+DR+ | Abs_Value | 11 | 11 | 0 | 88.9 | 67.23 | 49.17 - 128.63 | 8.23 - 193.07 | 71.11 | 34.8 - 139.33 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 169.02 | 167.56 | 70 - 268.04 | 14.91 - 537.94 | 125.88 | 45.31 - 244.85 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 10.29 | 9.13 | 4.89 - 15.68 | 0.63 - 31.44 | 8.82 | 3.66 - 14.76 | Н/П* | Н/П* | ||||||||||
4+PD-1+ | Abs_Value | 11 | 11 | 0 | 138.29 | 71.58 | 95.99 - 180.59 | 31.78 - 262.8 | 132.83 | 96.83 - 170.43 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 83.27 | 52.91 | 52.01 - 114.54 | 23.07 - 198.47 | 79.56 | 45.64 - 98.1 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 55.01 | 24.32 | 40.64 - 69.39 | 8.71 - 95.48 | 53.46 | 45.38 - 69.83 | Н/П* | Н/П* | ||||||||||
4+TIGIT+ | Abs_Value | 11 | 11 | 0 | 65.3 | 30.88 | 47.05 - 83.55 | 9.38 - 126.92 | 64.95 | 55 - 74.97 | Н/П* | Н/П* | ||||||||||
4NV | Abs_Value | 11 | 11 | 0 | 94 | 128.87 | 17.84 - 170.15 | 6.21 - 420.64 | 45.02 | 11.53 - 100.8 | Н/П* | Н/П* | ||||||||||
4NV(СТАР2) | Abs_Value | 11 | 11 | 0 | 97.76 | 149.09 | 9.65 - 185.86 | 1.3 - 510.77 | 49.15 | 8.92 - 96.81 | Н/П* | Н/П* | ||||||||||
4NV_TH1 | Abs_Value | 11 | 11 | 0 | 6.91 | 9.37 | 1.37 - 12.44 | 0.25 - 29.1 | 3.44 | 0.76 - 7.04 | Н/П* | Н/П* | ||||||||||
4NV_TH17 | Abs_Value | 11 | 11 | 0 | 1.98 | 1.99 | 0.8 - 3.16 | 0.16 - 6.19 | 1.44 | 0.51 - 2.58 | Н/П* | Н/П* | ||||||||||
4NV_Th17TO1 | Abs_Value | 11 | 11 | 0 | 0.69 | 0.68 | 0.28 - 1.09 | 0 - 1.82 | 0.46 | 0.1 - 1.17 | Н/П* | Н/П* | ||||||||||
4NV_TH2 | Abs_Value | 11 | 11 | 0 | 8.76 | 13.32 | 0.89 - 16.63 | 0.21 - 40.56 | 2.29 | 1.3 - 7.28 | Н/П* | Н/П* | ||||||||||
4NV_TH22 | Abs_Value | 11 | 11 | 0 | 0.15 | 0.19 | 0.04 - 0.27 | 0 - 0.62 | 0.06 | 0.03 - 0.18 | Н/П* | Н/П* | ||||||||||
4NV+226+ | Abs_Value | 11 | 11 | 0 | 87.24 | 146.03 | 0.94 - 173.54 | 1.18 - 502.6 | 42.25 | 7.16 - 82.61 | Н/П* | Н/П* | ||||||||||
4NV+39+ | Abs_Value | 11 | 11 | 0 | 1.66 | 1.79 | 0.6 - 2.72 | 0.02 - 4.32 | 0.51 | 0.12 - 3.09 | Н/П* | Н/П* | ||||||||||
4NV+DR+ | Abs_Value | 11 | 11 | 0 | 2.91 | 2.8 | 1.25 - 4.56 | 0.06 - 7.64 | 3.2 | 0.27 - 4.87 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 91.34 | 140.61 | 8.25 - 174.44 | 1.08 - 481.6 | 45.15 | 7.96 - 89.58 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 2.58 | 3.72 | 0.37 - 4.78 | 0 - 11.49 | 1.13 | 0.18 - 2.86 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 2.39 | 3.59 | 0.27 - 4.51 | 0.15 - 12.43 | 1.02 | 0.42 - 2.62 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 1.45 | 1.57 | 0.52 - 2.37 | 0.03 - 5.24 | 1.15 | 0.28 - 2.18 | Н/П* | Н/П* | ||||||||||
4NV+PD1+ | Abs_Value | 11 | 11 | 0 | 3.84 | 5.01 | 0.88 - 6.8 | 0.21 - 17.68 | 2.86 | 0.75 - 4.59 | Н/П* | Н/П* | ||||||||||
4NV+TIGIT+ | Abs_Value | 11 | 11 | 0 | 4.02 | 5.04 | 1.05 - 7 | 0.03 - 16.74 | 2.98 | 0.44 - 4.8 | Н/П* | Н/П* | ||||||||||
4ЕМ | Abs_Value | 11 | 11 | 0 | 23.6 | 38.73 | 0.72 - 46.49 | 0.38 - 135.76 | 6.94 | 4.53 - 24.3 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH1 | Abs_Value | 11 | 11 | 0 | 8.99 | 12.65 | 1.52 - 16.47 | 0.08 - 41.51 | 3.69 | 0.85 - 12.85 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH17 | Abs_Value | 11 | 11 | 0 | 0.02 | 0.03 | 0 - 0.04 | 0 - 0.11 | 0.01 | 0 - 0.04 | Н/П* | Н/П* | ||||||||||
4ЕМ_Th17TO1 | Abs_Value | 11 | 11 | 0 | 0.18 | 0.21 | 0.05 - 0.3 | 0.01 - 0.61 | 0.05 | 0.03 - 0.32 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH2 | Abs_Value | 11 | 11 | 0 | 1.32 | 3.66 | -0.85 - 3.48 | 0.01 - 12.33 | 0.23 | 0.1 - 0.35 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH22 | Abs_Value | 11 | 11 | 0 | 0 | 0 | 0 - 0.01 | 0 - 0.01 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ЕМ+226+ | Abs_Value | 11 | 11 | 0 | 112.6 | 58.93 | 77.78 - 147.43 | 36.25 - 233.28 | 115.17 | 67.72 - 144.4 | Н/П* | Н/П* | ||||||||||
4ЕМ+39+ | Abs_Value | 11 | 11 | 0 | 33.27 | 23.41 | 19.43 - 47.11 | 3.55 - 66.1 | 32.47 | 14.72 - 53.53 | Н/П* | Н/П* | ||||||||||
4ЕМ+DR+ | Abs_Value | 11 | 11 | 0 | 59.19 | 49.1 | 30.17 - 88.21 | 7.54 - 169.88 | 45.31 | 22.39 - 86.64 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT- | Abs_Value | 11 | 11 | 0 | 29.45 | 24.24 | 15.13 - 43.78 | 5.75 - 67.06 | 17.26 | 11.39 - 49.37 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 2.69 | 1.88 | 1.58 - 3.8 | 0.32 - 5.74 | 3.05 | 0.98 - 4.2 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+ | Abs_Value | 11 | 11 | 0 | 84.6 | 55 | 52.1 - 117.11 | 28.52 - 229.28 | 75.61 | 50.19 - 100.5 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT- | Abs_Value | 11 | 11 | 0 | 54.13 | 44.26 | 27.97 - 80.29 | 21.05 - 175.37 | 43.85 | 24.53 - 62.18 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 30.47 | 13.79 | 22.32 - 38.62 | 7.43 - 53.91 | 31.76 | 23.22 - 34.75 | Н/П* | Н/П* | ||||||||||
4ЕМ+TIGIT+ | Abs_Value | 11 | 11 | 0 | 33.16 | 13.77 | 25.02 - 41.29 | 7.96 - 54.23 | 35.86 | 25.41 - 39.15 | Н/П* | Н/П* | ||||||||||
4ЕМTM | Abs_Value | 11 | 11 | 0 | 116.74 | 58.8 | 81.99 - 151.5 | 39.04 - 235.35 | 118.96 | 70.64 - 149.95 | Н/П* | Н/П* | ||||||||||
4СМ | Abs_Value | 11 | 11 | 0 | 82.27 | 64.92 | 43.9 - 120.63 | 6.36 - 204.91 | 96.73 | 26.33 - 114.43 | Н/П* | Н/П* | ||||||||||
4СМ(СТАР2) | Abs_Value | 11 | 11 | 0 | 65.12 | 54.23 | 33.07 - 97.16 | 5.4 - 150.09 | 69.58 | 12.28 - 95.96 | Н/П* | Н/П* | ||||||||||
4СМ_TH1 | Abs_Value | 11 | 11 | 0 | 4.48 | 6.89 | 0.4 - 8.55 | 0.17 - 24.29 | 2.37 | 1.2 - 3.37 | Н/П* | Н/П* | ||||||||||
4СМ_TH17 | Abs_Value | 11 | 11 | 0 | 7.88 | 6.56 | 4 - 11.76 | 1.54 - 20.3 | 4.17 | 2.85 - 12.14 | Н/П* | Н/П* | ||||||||||
4СМ_Th17TO1 | Abs_Value | 11 | 11 | 0 | 1.69 | 1.82 | 0.61 - 2.76 | 0.01 - 5.86 | 1 | 0.51 - 2.18 | Н/П* | Н/П* | ||||||||||
4СМ_TH2 | Abs_Value | 11 | 11 | 0 | 8.01 | 11.02 | 1.5 - 14.52 | 0.84 - 37.81 | 2.11 | 1.93 - 9.41 | Н/П* | Н/П* | ||||||||||
4СМ_TH22 | Abs_Value | 11 | 11 | 0 | 1.64 | 2.41 | 0.22 - 3.07 | 0.02 - 7.61 | 0.49 | 0.24 - 2.1 | Н/П* | Н/П* | ||||||||||
4СМ+226+ | Abs_Value | 11 | 11 | 0 | 61.44 | 51.86 | 30.79 - 92.08 | 4.91 - 144.32 | 63.53 | 11.59 - 91.57 | Н/П* | Н/П* | ||||||||||
4СМ+39+ | Abs_Value | 11 | 11 | 0 | 15.09 | 17.6 | 4.69 - 25.49 | 0.26 - 50.51 | 6.36 | 0.91 - 24.68 | Н/П* | Н/П* | ||||||||||
4СМ+DR+ | Abs_Value | 11 | 11 | 0 | 11.87 | 11.99 | 4.78 - 18.96 | 0.3 - 29.76 | 4.52 | 3.34 - 23.4 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT- | Abs_Value | 11 | 11 | 0 | 30.48 | 28.97 | 13.36 - 47.6 | 2.17 - 79.64 | 31.41 | 4.29 - 50.23 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 2.83 | 3.02 | 1.05 - 4.62 | 0.04 - 9.53 | 2.72 | 0.64 - 3.35 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+ | Abs_Value | 11 | 11 | 0 | 31.8 | 25.92 | 16.48 - 47.12 | 1.57 - 63.6 | 29.07 | 8.04 - 60.52 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT- | Abs_Value | 11 | 11 | 0 | 15.07 | 13.01 | 7.38 - 22.76 | 1.16 - 38.18 | 11.31 | 4.11 - 26.82 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 16.73 | 13.91 | 8.51 - 24.95 | 0.41 - 38.43 | 14.64 | 3.93 - 27.2 | Н/П* | Н/П* | ||||||||||
4СМ+TIGIT+ | Abs_Value | 11 | 11 | 0 | 19.56 | 16.53 | 9.79 - 29.33 | 0.45 - 47.95 | 18.23 | 4.45 - 29.99 | Н/П* | Н/П* | ||||||||||
4ТM_TH1 | Abs_Value | 11 | 11 | 0 | 8.94 | 6.31 | 5.21 - 12.67 | 2.22 - 23.42 | 9.6 | 3.4 - 11.51 | Н/П* | Н/П* | ||||||||||
4ТM_TH17 | Abs_Value | 11 | 11 | 0 | 6.69 | 3.22 | 4.79 - 8.6 | 0.67 - 12.4 | 7.05 | 5.08 - 7.62 | Н/П* | Н/П* | ||||||||||
4ТM_Th17TO1 | Abs_Value | 11 | 11 | 0 | 2.81 | 1.95 | 1.66 - 3.97 | 0.49 - 6.92 | 2.57 | 1.31 - 4.11 | Н/П* | Н/П* | ||||||||||
4ТM_TH2 | Abs_Value | 11 | 11 | 0 | 3.88 | 3.58 | 1.76 - 5.99 | 0.65 - 10.5 | 2.91 | 1.32 - 4.89 | Н/П* | Н/П* | ||||||||||
4ТM_TH22 | Abs_Value | 11 | 11 | 0 | 5.01 | 5.46 | 1.78 - 8.23 | 0.36 - 15.88 | 2.75 | 1.41 - 5.73 | Н/П* | Н/П* | ||||||||||
4ТREG | Abs_Value | 11 | 11 | 0 | 5.7 | 5.55 | 2.42 - 8.98 | 0.16 - 18.58 | 5.59 | 1.05 - 7.72 | Н/П* | Н/П* | ||||||||||
4ТREG(СТАР2) | Abs_Value | 11 | 11 | 0 | 141.67 | 106.82 | 78.54 - 204.79 | 19.25 - 336.13 | 98.26 | 74.19 - 184.1 | Н/П* | Н/П* | ||||||||||
4ТREG_TH1 | Abs_Value | 11 | 11 | 0 | 0.44 | 0.39 | 0.21 - 0.68 | 0.05 - 1.08 | 0.37 | 0.12 - 0.74 | Н/П* | Н/П* | ||||||||||
4ТREG_TH17 | Abs_Value | 11 | 11 | 0 | 3.75 | 2.39 | 2.34 - 5.17 | 0.91 - 8.42 | 3.65 | 2.01 - 5.1 | Н/П* | Н/П* | ||||||||||
4ТREG_Th17TO1 | Abs_Value | 11 | 11 | 0 | 0.2 | 0.15 | 0.11 - 0.28 | 0.01 - 0.39 | 0.18 | 0.06 - 0.33 | Н/П* | Н/П* | ||||||||||
4ТREG_TH2 | Abs_Value | 11 | 11 | 0 | 2.9 | 2.9 | 1.18 - 4.61 | 0.31 - 8.68 | 1.15 | 0.9 - 4.55 | Н/П* | Н/П* | ||||||||||
4ТREG_TH22 | Abs_Value | 11 | 11 | 0 | 3.71 | 3.64 | 1.56 - 5.86 | 0.7 - 11.45 | 2.16 | 1.2 - 5.39 | Н/П* | Н/П* | ||||||||||
4ТЕ | Abs_Value | 11 | 11 | 0 | 9.12 | 11.87 | 2.11 - 16.14 | 0.42 - 41.3 | 4.96 | 1.38 - 12.13 | Н/П* | Н/П* | ||||||||||
4ТЕ(СТАР2) | Abs_Value | 11 | 11 | 0 | 29.57 | 20.51 | 17.45 - 41.69 | 5.39 - 74.77 | 24.32 | 19.09 - 31.91 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH1 | Abs_Value | 11 | 11 | 0 | 3.99 | 7.86 | -0.65 - 8.64 | 0.16 - 27.05 | 0.94 | 0.23 - 3.48 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH17 | Abs_Value | 11 | 11 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.03 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ_Th17TO1 | Abs_Value | 11 | 11 | 0 | 0.21 | 0.56 | -0.12 - 0.54 | 0 - 1.89 | 0.01 | 0 - 0.06 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH2 | Abs_Value | 11 | 11 | 0 | 0.25 | 0.4 | 0.01 - 0.49 | 0 - 1.33 | 0.11 | 0.03 - 0.22 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH22 | Abs_Value | 11 | 11 | 0 | 0.01 | 0.02 | 0 - 0.02 | 0 - 0.06 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ+226+ | Abs_Value | 11 | 11 | 0 | 27.32 | 19.92 | 15.55 - 39.09 | 4.64 - 73.35 | 22.18 | 16.86 - 29.79 | Н/П* | Н/П* | ||||||||||
4ТЕ+39+ | Abs_Value | 11 | 11 | 0 | 5.06 | 6.29 | 1.34 - 8.78 | 0.56 - 20.16 | 2.04 | 1.27 - 5.28 | Н/П* | Н/П* | ||||||||||
4ТЕ+DR+ | Abs_Value | 11 | 11 | 0 | 14.02 | 14.93 | 5.2 - 22.85 | 0.32 - 51.79 | 10.36 | 3.21 - 18.85 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 11.75 | 8.82 | 6.54 - 16.96 | 3.69 - 28.88 | 8.21 | 5.44 - 13.73 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 1.44 | 1.34 | 0.65 - 2.23 | 0.1 - 3.76 | 1.3 | 0.37 - 2.13 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+ | Abs_Value | 11 | 11 | 0 | 16.39 | 12.56 | 8.97 - 23.81 | 1.16 - 45.19 | 15.93 | 7.48 - 22.66 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 10.92 | 10.16 | 4.92 - 16.92 | 0.66 - 35.88 | 6.17 | 4.48 - 15.07 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 5.47 | 3.87 | 3.18 - 7.75 | 0.5 - 12.65 | 3.33 | 2.97 - 7.54 | Н/П* | Н/П* | ||||||||||
4ТЕ+TIGIT+ | Abs_Value | 11 | 11 | 0 | 6.9 | 5.09 | 3.9 - 9.91 | 0.6 - 16.41 | 5.24 | 3.37 - 9.19 | Н/П* | Н/П* | ||||||||||
4ТМ | Abs_Value | 11 | 11 | 0 | 83.29 | 28.69 | 66.34 - 100.24 | 36.54 - 131.83 | 82.01 | 63.66 - 105.58 | Н/П* | Н/П* | ||||||||||
8+ | Abs_Value | 11 | 11 | 0 | 578.84 | 685.07 | 173.99 - 983.69 | 30 - 2195.9 | 217.02 | 159.23 - 742.49 | Н/П* | Н/П* | ||||||||||
8+ (IM STAT) | Abs_Value | 11 | 11 | 0 | 734.51 | 779.31 | 273.97 - 1195.06 | 32.41 - 2619.95 | 392.04 | 231.98 - 846.94 | Н/П* | Н/П* | ||||||||||
8+226+ | Abs_Value | 11 | 11 | 0 | 926.56 | 884.39 | 403.92 - 1449.2 | 46.34 - 3173.45 | 512.62 | 396.99 - 1064.24 | Н/П* | Н/П* | ||||||||||
8+39+ | Abs_Value | 11 | 11 | 0 | 110.84 | 179.27 | 4.89 - 216.78 | 8.23 - 628.04 | 47.55 | 32.28 - 73.58 | Н/П* | Н/П* | ||||||||||
8+DR+ | Abs_Value | 11 | 11 | 0 | 714.36 | 823.08 | 227.95 - 1200.77 | 71.6 - 2878.79 | 332.58 | 275.06 - 883.81 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 402.69 | 397.54 | 167.76 - 637.62 | 11.43 - 1404.23 | 233.57 | 196.53 - 526.23 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 191.36 | 216.53 | 63.4 - 319.32 | 22.57 - 615.13 | 126.36 | 51.13 - 197.78 | Н/П* | Н/П* | ||||||||||
8+PD-1+ | Abs_Value | 11 | 11 | 0 | 403.19 | 372.5 | 183.06 - 623.32 | 38.01 - 1266.83 | 251.83 | 164.33 - 556.48 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 198.03 | 216.01 | 70.37 - 325.68 | 3.48 - 749.39 | 118.32 | 62.39 - 249.91 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 205.16 | 164.35 | 108.04 - 302.29 | 34.52 - 517.43 | 128.21 | 90.21 - 306.57 | Н/П* | Н/П* | ||||||||||
8+TIGIT+ | Abs_Value | 11 | 11 | 0 | 396.52 | 349.93 | 189.72 - 603.32 | 62.49 - 1118.31 | 272 | 161.54 - 486.27 | Н/П* | Н/П* | ||||||||||
8EMTM | Abs_Value | 11 | 11 | 0 | 156.08 | 149.71 | 67.61 - 244.55 | 4.67 - 481.44 | 104.12 | 57 - 203.48 | Н/П* | Н/П* | ||||||||||
8EMTM+226+ | Abs_Value | 11 | 11 | 0 | 142.66 | 141.53 | 59.02 - 226.3 | 2.47 - 469.49 | 100.18 | 51.53 - 171.7 | Н/П* | Н/П* | ||||||||||
8EMTM+39+ | Abs_Value | 11 | 11 | 0 | 21.87 | 24.79 | 7.22 - 36.51 | 0.5 - 82.84 | 10.76 | 3.92 - 33.37 | Н/П* | Н/П* | ||||||||||
8EMTM+DR+ | Abs_Value | 11 | 11 | 0 | 124.38 | 130.01 | 47.55 - 201.21 | 4.32 - 412.87 | 79.07 | 45.46 - 128.94 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 41.89 | 36.39 | 20.38 - 63.4 | 0.24 - 123.49 | 27.51 | 18.51 - 52.01 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 15.38 | 20.08 | 3.52 - 27.25 | 0.18 - 61.97 | 7.82 | 2.29 - 19.7 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+ | Abs_Value | 11 | 11 | 0 | 98.81 | 113.49 | 31.74 - 165.88 | 4.25 - 396.29 | 56.28 | 33.81 - 121.02 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 48.74 | 57.28 | 14.89 - 82.59 | 0.45 - 196.08 | 30.56 | 13.74 - 63.82 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 50.07 | 57.79 | 15.92 - 84.22 | 3.8 - 200.2 | 36.49 | 10.63 - 63.03 | Н/П* | Н/П* | ||||||||||
8EMTM+TIGIT+ | Abs_Value | 11 | 11 | 0 | 65.45 | 70.67 | 23.68 - 107.21 | 3.98 - 226.37 | 39.85 | 12.86 - 86.24 | Н/П* | Н/П* | ||||||||||
8NV | Abs_Value | 11 | 11 | 0 | 35.12 | 34.31 | 14.84 - 55.39 | 3.36 - 103.28 | 16.56 | 7.3 - 57.15 | Н/П* | Н/П* | ||||||||||
8NV(СТАР2) | Abs_Value | 11 | 11 | 0 | 54.65 | 62.03 | 18 - 91.31 | 0.85 - 214.03 | 54.6 | 8.61 - 74.13 | Н/П* | Н/П* | ||||||||||
8NV+226+ | Abs_Value | 11 | 11 | 0 | 48.04 | 58.86 | 13.26 - 82.83 | 0.83 - 205.18 | 47.85 | 6.01 - 60.43 | Н/П* | Н/П* | ||||||||||
8NV+39+ | Abs_Value | 11 | 11 | 0 | 4.06 | 5.8 | 0.63 - 7.49 | 0.13 - 14.96 | 0.8 | 0.41 - 6.58 | Н/П* | Н/П* | ||||||||||
8NV+DR+ | Abs_Value | 11 | 11 | 0 | 7.23 | 6.4 | 3.44 - 11.01 | 0.46 - 16.71 | 4.59 | 2.16 - 13.91 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 43.46 | 59.83 | 8.11 - 78.82 | 0.2 - 208.28 | 37.74 | 5.12 - 57.46 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 4.24 | 6.3 | 0.52 - 7.97 | 0 - 21.7 | 1.52 | 0.42 - 5.46 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+ | Abs_Value | 11 | 11 | 0 | 6.95 | 6.26 | 3.25 - 10.64 | 0.24 - 19.42 | 4.65 | 2.4 - 9.42 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 2.24 | 2.66 | 0.67 - 3.81 | 0 - 8.15 | 0.95 | 0.33 - 3.06 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 4.71 | 4.68 | 1.94 - 7.47 | 0.24 - 12.49 | 2.25 | 1.27 - 8.82 | Н/П* | Н/П* | ||||||||||
8NV+TIGIT+ | Abs_Value | 11 | 11 | 0 | 8.95 | 9.6 | 3.28 - 14.62 | 0.41 - 29.4 | 3.77 | 1.65 - 16.06 | Н/П* | Н/П* | ||||||||||
8TREG | Abs_Value | 11 | 11 | 0 | 596 | 680.43 | 193.88 - 998.11 | 29.13 - 2207.38 | 265.06 | 199.18 - 720.62 | Н/П* | Н/П* | ||||||||||
8ЕМ | Abs_Value | 11 | 11 | 0 | 142.53 | 143.35 | 57.82 - 227.24 | 4.7 - 435.49 | 74.23 | 36.04 - 199.55 | Н/П* | Н/П* | ||||||||||
8СМ | Abs_Value | 11 | 11 | 0 | 13.49 | 15.47 | 4.35 - 22.64 | 0.6 - 51.2 | 7.36 | 2.34 - 21.35 | Н/П* | Н/П* | ||||||||||
8СМ(СТАР2) | Abs_Value | 11 | 11 | 0 | 8.6 | 9.75 | 2.84 - 14.37 | 0.04 - 33.96 | 4.01 | 2.63 - 12.02 | Н/П* | Н/П* | ||||||||||
8СМ+226+ | Abs_Value | 11 | 11 | 0 | 5.99 | 5.4 | 2.79 - 9.18 | 0.04 - 16.8 | 3.55 | 2.09 - 8.3 | Н/П* | Н/П* | ||||||||||
8СМ+39+ | Abs_Value | 11 | 11 | 0 | 1.55 | 1.93 | 0.41 - 2.69 | 0.02 - 5.23 | 0.87 | 0.17 - 2.06 | Н/П* | Н/П* | ||||||||||
8СМ+DR+ | Abs_Value | 11 | 11 | 0 | 6.71 | 8.7 | 1.57 - 11.85 | 0.02 - 30.43 | 3.64 | 1.84 - 8.99 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 1.88 | 2.22 | 0.56 - 3.19 | 0.02 - 7.08 | 0.78 | 0.29 - 2.73 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 1.44 | 2.54 | -0.06 - 2.94 | 0 - 8.77 | 0.41 | 0.12 - 1.6 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+ | Abs_Value | 11 | 11 | 0 | 5.28 | 6.19 | 1.62 - 8.94 | 0.02 - 21.78 | 3.17 | 1.73 - 7.04 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 0.77 | 0.64 | 0.39 - 1.14 | 0 - 2.18 | 0.82 | 0.24 - 0.98 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 4.51 | 6.04 | 0.94 - 8.09 | 0.01 - 21.05 | 2.23 | 1.12 - 5.47 | Н/П* | Н/П* | ||||||||||
8СМ+TIGIT+ | Abs_Value | 11 | 11 | 0 | 5.96 | 8.52 | 0.92 - 10.99 | 0.01 - 29.82 | 3.21 | 1.28 - 6.63 | Н/П* | Н/П* | ||||||||||
8ТЕ | Abs_Value | 11 | 11 | 0 | 622.8 | 761.49 | 172.78 - 1072.81 | 23.09 - 2714.05 | 306.64 | 199.77 - 658.64 | Н/П* | Н/П* | ||||||||||
8ТЕ(СТАР2) | Abs_Value | 11 | 11 | 0 | 759.66 | 830.66 | 268.77 - 1250.55 | 88.95 - 2905.58 | 391.48 | 268.78 - 855.84 | Н/П* | Н/П* | ||||||||||
8ТЕ+226+ | Abs_Value | 11 | 11 | 0 | 714.93 | 813.85 | 233.98 - 1195.88 | 37.92 - 2858.44 | 332.25 | 262.61 - 814.62 | Н/П* | Н/П* | ||||||||||
8ТЕ+39+ | Abs_Value | 11 | 11 | 0 | 74.62 | 137.84 | -6.84 - 156.08 | 7.19 - 479.15 | 18.13 | 15.25 - 46.38 | Н/П* | Н/П* | ||||||||||
8ТЕ+DR+ | Abs_Value | 11 | 11 | 0 | 562.06 | 750.18 | 118.74 - 1005.39 | 66.62 - 2623.56 | 243.25 | 155.56 - 645.34 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT- | Abs_Value | 11 | 11 | 0 | 311.97 | 376.13 | 89.69 - 534.25 | 5.08 - 1283.87 | 141.19 | 96.18 - 427.02 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT+ | Abs_Value | 11 | 11 | 0 | 166.89 | 194.49 | 51.96 - 281.83 | 17.28 - 551.54 | 100.26 | 43.13 - 159.9 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+ | Abs_Value | 11 | 11 | 0 | 280.8 | 304.9 | 100.61 - 460.98 | 33.55 - 1070.17 | 158.31 | 80.8 - 424.72 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT- | Abs_Value | 11 | 11 | 0 | 144.03 | 192.95 | 30 - 258.05 | 3.04 - 682.96 | 61.42 | 39.01 - 193.3 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT+ | Abs_Value | 11 | 11 | 0 | 136.77 | 120.68 | 65.45 - 208.09 | 23.32 - 387.21 | 66.51 | 40.69 - 225.04 | Н/П* | Н/П* | ||||||||||
8ТЕ+TIGIT+ | Abs_Value | 11 | 11 | 0 | 303.66 | 292.71 | 130.68 - 476.65 | 42.68 - 938.75 | 228.72 | 82.7 - 354 | Н/П* | Н/П* | ||||||||||
8ТМ | Abs_Value | 11 | 11 | 0 | 33.69 | 24.31 | 19.32 - 48.05 | 5.82 - 76 | 26.42 | 14.67 - 52.75 | Н/П* | Н/П* | ||||||||||
TREG_CM | Abs_Value | 11 | 11 | 0 | 3.15 | 3.31 | 1.2 - 5.11 | 0.14 - 9.47 | 1.57 | 0.48 - 5.12 | Н/П* | Н/П* | ||||||||||
TREG_EMTM | Abs_Value | 11 | 11 | 0 | 26.34 | 17.66 | 15.9 - 36.78 | 5.79 - 53.46 | 22.45 | 10.29 - 42.3 | Н/П* | Н/П* | ||||||||||
TREG_NV | Abs_Value | 11 | 11 | 0 | 3 | 2.92 | 1.28 - 4.73 | 0.01 - 7.25 | 1.78 | 0.46 - 5.58 | Н/П* | Н/П* | ||||||||||
TREG_TE | Abs_Value | 11 | 11 | 0 | 4.08 | 3.56 | 1.98 - 6.18 | 0.26 - 10.4 | 2.85 | 1.02 - 7.13 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT- | Abs_Value | 11 | 11 | 0 | 1.84 | 1.28 | 1.08 - 2.59 | 0.2 - 4.49 | 1.73 | 0.89 - 2.34 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT+ | Abs_Value | 11 | 11 | 0 | 8.56 | 6.91 | 4.47 - 12.64 | 0.73 - 19.26 | 7.93 | 2.12 - 13.51 | Н/П* | Н/П* | ||||||||||
TREG+226+ | Abs_Value | 11 | 11 | 0 | 26.66 | 17.13 | 16.54 - 36.79 | 5.33 - 51.13 | 24.99 | 13.42 - 38.48 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT- | Abs_Value | 11 | 11 | 0 | 3.05 | 1.72 | 2.04 - 4.07 | 0.95 - 6.15 | 3.59 | 1.37 - 4.12 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT+ | Abs_Value | 11 | 11 | 0 | 23.61 | 16.25 | 14 - 33.21 | 4.36 - 47.29 | 23.7 | 9.63 - 34.4 | Н/П* | Н/П* | ||||||||||
TREG+39+ | Abs_Value | 11 | 11 | 0 | 24.66 | 19.74 | 13 - 36.33 | 5.68 - 68.05 | 19.08 | 12.11 - 26.92 | Н/П* | Н/П* | ||||||||||
TREG+DR+ | Abs_Value | 11 | 11 | 0 | 26.32 | 19.69 | 14.68 - 37.95 | 4.39 - 59.8 | 25.66 | 7.96 - 41.74 | Н/П* | Н/П* | ||||||||||
TREG+PD-1+ | Abs_Value | 11 | 11 | 0 | 17.43 | 13.77 | 9.29 - 25.57 | 4.68 - 47.96 | 16.01 | 6.75 - 18.88 | Н/П* | Н/П* | ||||||||||
TREG+TIGIT+ | Abs_Value | 11 | 11 | 0 | 32.16 | 22.25 | 19.02 - 45.31 | 5.35 - 66.55 | 29.06 | 12.43 - 50.36 | Н/П* | Н/П* | ||||||||||
ДЕНЬ ХРРТПХ +90 | 4_TFH | Abs_Value | 16 | 16 | 0 | 35.35 | 23.89 | 23.64 - 47.05 | 3.11 - 96.06 | 28.78 | 21.76 - 50.15 | Н/П* | Н/П* | |||||||||
4_TH1 | Abs_Value | 16 | 16 | 0 | 31.21 | 29.23 | 16.89 - 45.54 | 1.9 - 112.66 | 21.99 | 15.62 - 32.29 | Н/П* | Н/П* | ||||||||||
4_TH17 | Abs_Value | 16 | 16 | 0 | 24.13 | 15.61 | 16.48 - 31.78 | 6.93 - 58.39 | 19.17 | 12.69 - 32.93 | Н/П* | Н/П* | ||||||||||
4_Th17TO1 | Abs_Value | 16 | 16 | 0 | 6.09 | 4.39 | 3.94 - 8.24 | 0.23 - 16.13 | 4.89 | 3.51 - 8.74 | Н/П* | Н/П* | ||||||||||
4_TH2 | Abs_Value | 16 | 16 | 0 | 27.11 | 18.08 | 18.25 - 35.97 | 8.43 - 76.49 | 20.94 | 14.14 - 35.85 | Н/П* | Н/П* | ||||||||||
4_TH22 | Abs_Value | 16 | 16 | 0 | 9.15 | 7.62 | 5.42 - 12.88 | 0.67 - 23.59 | 6.45 | 3.86 - 12.08 | Н/П* | Н/П* | ||||||||||
4+ | Abs_Value | 16 | 16 | 0 | 132.22 | 82.34 | 91.87 - 172.56 | 20.84 - 298.94 | 110.26 | 66.25 - 190.14 | Н/П* | Н/П* | ||||||||||
4+ (IM STAT) | Abs_Value | 16 | 16 | 0 | 103.84 | 67.1 | 70.96 - 136.72 | 34.32 - 275.92 | 98.9 | 52.08 - 129.82 | Н/П* | Н/П* | ||||||||||
4+226+ | Abs_Value | 16 | 16 | 0 | 287.69 | 154.08 | 212.19 - 363.19 | 87.94 - 576.94 | 257.19 | 176.03 - 410.75 | Н/П* | Н/П* | ||||||||||
4+39+ | Abs_Value | 16 | 16 | 0 | 55.03 | 60.37 | 25.45 - 84.61 | 1.04 - 246.85 | 41.24 | 21.45 - 62.04 | Н/П* | Н/П* | ||||||||||
4+DR+ | Abs_Value | 16 | 16 | 0 | 93.94 | 80.53 | 54.48 - 133.4 | 25.31 - 271.33 | 51.07 | 39.47 - 108.97 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 141.1 | 95.38 | 94.36 - 187.84 | 37.81 - 332.69 | 131.49 | 64.39 - 171.18 | Н/П* | Н/П* | ||||||||||
4+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 11.6 | 10.85 | 6.29 - 16.92 | 1.69 - 46.7 | 7.74 | 5.22 - 15.71 | Н/П* | Н/П* | ||||||||||
4+PD-1+ | Abs_Value | 16 | 16 | 0 | 155.06 | 104.07 | 104.07 - 206.05 | 30.06 - 400.09 | 125.63 | 86.15 - 191.77 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 85.42 | 58.08 | 56.96 - 113.88 | 15.87 - 247.58 | 68.49 | 50 - 101.27 | Н/П* | Н/П* | ||||||||||
4+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 69.64 | 53.87 | 43.24 - 96.04 | 14.19 - 235.06 | 56.25 | 37.41 - 90.5 | Н/П* | Н/П* | ||||||||||
4+TIGIT+ | Abs_Value | 16 | 16 | 0 | 81.25 | 58.37 | 52.65 - 109.85 | 19.56 - 252.76 | 72.45 | 40.14 - 98.27 | Н/П* | Н/П* | ||||||||||
4NV | Abs_Value | 16 | 16 | 0 | 85.71 | 81.73 | 45.66 - 125.76 | 13.04 - 299.61 | 53.86 | 31.77 - 101.04 | Н/П* | Н/П* | ||||||||||
4NV(СТАР2) | Abs_Value | 16 | 16 | 0 | 80.63 | 80.6 | 41.14 - 120.12 | 6.3 - 304.68 | 47.43 | 30.78 - 103.91 | Н/П* | Н/П* | ||||||||||
4NV_TH1 | Abs_Value | 16 | 16 | 0 | 5.61 | 7.86 | 1.76 - 9.46 | 0.57 - 30 | 2.05 | 0.92 - 6.64 | Н/П* | Н/П* | ||||||||||
4NV_TH17 | Abs_Value | 16 | 16 | 0 | 2.48 | 2.38 | 1.31 - 3.64 | 0.27 - 8.85 | 1.77 | 0.71 - 3.14 | Н/П* | Н/П* | ||||||||||
4NV_Th17TO1 | Abs_Value | 16 | 16 | 0 | 0.54 | 0.61 | 0.24 - 0.84 | 0.04 - 2.08 | 0.34 | 0.1 - 0.82 | Н/П* | Н/П* | ||||||||||
4NV_TH2 | Abs_Value | 16 | 16 | 0 | 9.6 | 13.38 | 3.04 - 16.16 | 0.58 - 57.11 | 5.97 | 3.75 - 10.43 | Н/П* | Н/П* | ||||||||||
4NV_TH22 | Abs_Value | 16 | 16 | 0 | 0.18 | 0.14 | 0.11 - 0.25 | 0.02 - 0.54 | 0.16 | 0.11 - 0.2 | Н/П* | Н/П* | ||||||||||
4NV+226+ | Abs_Value | 16 | 16 | 0 | 73.83 | 78.87 | 35.18 - 112.47 | 4.85 - 302.56 | 41.42 | 23.72 - 96.07 | Н/П* | Н/П* | ||||||||||
4NV+39+ | Abs_Value | 16 | 16 | 0 | 1.88 | 2.22 | 0.79 - 2.96 | 0.05 - 8 | 1.49 | 0.31 - 2.26 | Н/П* | Н/П* | ||||||||||
4NV+DR+ | Abs_Value | 16 | 16 | 0 | 5.04 | 4.84 | 2.67 - 7.41 | 0.13 - 15.82 | 3.55 | 1.77 - 6.32 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 73.63 | 76.16 | 36.31 - 110.95 | 3.6 - 289.92 | 41.78 | 27.61 - 96.54 | Н/П* | Н/П* | ||||||||||
4NV+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 2.24 | 3.68 | 0.44 - 4.05 | 0.04 - 15.6 | 1.2 | 0.96 - 1.83 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 2.88 | 2.51 | 1.65 - 4.11 | 0.07 - 9.06 | 1.81 | 0.99 - 4.26 | Н/П* | Н/П* | ||||||||||
4NV+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 1.87 | 1.83 | 0.97 - 2.77 | 0.08 - 6.13 | 1.14 | 0.63 - 2.24 | Н/П* | Н/П* | ||||||||||
4NV+PD1+ | Abs_Value | 16 | 16 | 0 | 4.75 | 4.08 | 2.75 - 6.75 | 0.16 - 15.19 | 3.55 | 1.84 - 6.1 | Н/П* | Н/П* | ||||||||||
4NV+TIGIT+ | Abs_Value | 16 | 16 | 0 | 4.11 | 4.54 | 1.89 - 6.34 | 0.13 - 18.1 | 2.45 | 1.63 - 4.05 | Н/П* | Н/П* | ||||||||||
4ЕМ | Abs_Value | 16 | 16 | 0 | 22.06 | 50.17 | -2.52 - 46.64 | 0.23 - 203.95 | 4.06 | 2.05 - 16.96 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH1 | Abs_Value | 16 | 16 | 0 | 3.88 | 5.53 | 1.17 - 6.59 | 0 - 19.39 | 1.69 | 0.2 - 4.23 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH17 | Abs_Value | 16 | 16 | 0 | 0.04 | 0.07 | 0.01 - 0.08 | 0 - 0.23 | 0.01 | 0 - 0.03 | Н/П* | Н/П* | ||||||||||
4ЕМ_Th17TO1 | Abs_Value | 16 | 16 | 0 | 0.19 | 0.33 | 0.03 - 0.35 | 0 - 1.11 | 0.06 | 0.01 - 0.17 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH2 | Abs_Value | 16 | 16 | 0 | 1.01 | 2.41 | -0.16 - 2.19 | 0 - 9.23 | 0.11 | 0.02 - 0.26 | Н/П* | Н/П* | ||||||||||
4ЕМ_TH22 | Abs_Value | 16 | 16 | 0 | 0.03 | 0.07 | -0.01 - 0.06 | 0 - 0.23 | 0 | 0 - 0 | Н/П* | Н/П* | ||||||||||
4ЕМ+226+ | Abs_Value | 16 | 16 | 0 | 121.53 | 79.15 | 82.75 - 160.31 | 19.75 - 301.44 | 123.64 | 52.94 - 142.43 | Н/П* | Н/П* | ||||||||||
4ЕМ+39+ | Abs_Value | 16 | 16 | 0 | 30.98 | 34.27 | 14.19 - 47.78 | 0.63 - 139.31 | 22.37 | 9.01 - 43.25 | Н/П* | Н/П* | ||||||||||
4ЕМ+DR+ | Abs_Value | 16 | 16 | 0 | 55.87 | 47.67 | 32.51 - 79.23 | 9.62 - 166.88 | 40.96 | 19.64 - 71.61 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT- | Abs_Value | 16 | 16 | 0 | 31.07 | 26.51 | 18.08 - 44.06 | 1.02 - 100.32 | 27.71 | 13.49 - 35.59 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 3.8 | 3.45 | 2.11 - 5.49 | 0.11 - 12.17 | 2.57 | 1.75 - 4.65 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+ | Abs_Value | 16 | 16 | 0 | 93.56 | 72.96 | 57.81 - 129.31 | 12.61 - 285.99 | 91.29 | 38.83 - 108.13 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT- | Abs_Value | 16 | 16 | 0 | 54.83 | 45.16 | 32.7 - 76.96 | 7.13 - 195.03 | 52.87 | 21.85 - 62.98 | Н/П* | Н/П* | ||||||||||
4ЕМ+PD1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 38.73 | 32.29 | 22.91 - 54.55 | 4.47 - 125.93 | 36.34 | 15.02 - 46.71 | Н/П* | Н/П* | ||||||||||
4ЕМ+TIGIT+ | Abs_Value | 16 | 16 | 0 | 42.53 | 33.2 | 26.26 - 58.8 | 5.34 - 130.53 | 43.38 | 16.63 - 52.8 | Н/П* | Н/П* | ||||||||||
4ЕМTM | Abs_Value | 16 | 16 | 0 | 128.43 | 80.9 | 88.79 - 168.07 | 20.66 - 302.94 | 135.97 | 56.8 - 149.8 | Н/П* | Н/П* | ||||||||||
4СМ | Abs_Value | 16 | 16 | 0 | 70.16 | 37.67 | 51.7 - 88.61 | 25.35 - 151.85 | 63.9 | 42.04 - 98.93 | Н/П* | Н/П* | ||||||||||
4СМ(СТАР2) | Abs_Value | 16 | 16 | 0 | 52.13 | 25.48 | 39.64 - 64.61 | 21.2 - 101.25 | 47.97 | 31.82 - 65.94 | Н/П* | Н/П* | ||||||||||
4СМ_TH1 | Abs_Value | 16 | 16 | 0 | 3.4 | 3.07 | 1.89 - 4.91 | 0.29 - 9.26 | 1.83 | 0.93 - 5.51 | Н/П* | Н/П* | ||||||||||
4СМ_TH17 | Abs_Value | 16 | 16 | 0 | 10.37 | 7.08 | 6.9 - 13.84 | 1.95 - 31.31 | 8.81 | 6.44 - 12.39 | Н/П* | Н/П* | ||||||||||
4СМ_Th17TO1 | Abs_Value | 16 | 16 | 0 | 1.16 | 0.95 | 0.69 - 1.63 | 0.11 - 2.67 | 1.06 | 0.23 - 1.75 | Н/П* | Н/П* | ||||||||||
4СМ_TH2 | Abs_Value | 16 | 16 | 0 | 7.03 | 4.75 | 4.7 - 9.36 | 1.16 - 18.38 | 6.35 | 3.74 - 9.61 | Н/П* | Н/П* | ||||||||||
4СМ_TH22 | Abs_Value | 16 | 16 | 0 | 1.55 | 1.51 | 0.81 - 2.29 | 0.03 - 4.89 | 0.84 | 0.61 - 2.35 | Н/П* | Н/П* | ||||||||||
4СМ+226+ | Abs_Value | 16 | 16 | 0 | 49.62 | 24.87 | 37.44 - 61.81 | 19.64 - 97.29 | 45.45 | 30.02 - 62.62 | Н/П* | Н/П* | ||||||||||
4СМ+39+ | Abs_Value | 16 | 16 | 0 | 12.83 | 10.42 | 7.72 - 17.93 | 0.16 - 33.92 | 11.07 | 6.71 - 18.46 | Н/П* | Н/П* | ||||||||||
4СМ+DR+ | Abs_Value | 16 | 16 | 0 | 10.1 | 6.87 | 6.74 - 13.47 | 1.2 - 24.58 | 8.29 | 5.28 - 12.93 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT- | Abs_Value | 16 | 16 | 0 | 19.96 | 12.91 | 13.63 - 26.28 | 2.11 - 50.45 | 21 | 11.18 - 27.37 | Н/П* | Н/П* | ||||||||||
4СМ+PD1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 3.18 | 3.19 | 1.62 - 4.75 | 0.21 - 13.54 | 2.63 | 1.15 - 4.08 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+ | Abs_Value | 16 | 16 | 0 | 28.99 | 15.2 | 21.54 - 36.44 | 9.67 - 60.98 | 25.05 | 18.68 - 37.73 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT- | Abs_Value | 16 | 16 | 0 | 11.22 | 5.06 | 8.74 - 13.71 | 3.55 - 20.95 | 9.83 | 7.28 - 14.47 | Н/П* | Н/П* | ||||||||||
4СМ+PD1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 17.76 | 11.18 | 12.28 - 23.24 | 6.08 - 44.81 | 14.8 | 8.86 - 24 | Н/П* | Н/П* | ||||||||||
4СМ+TIGIT+ | Abs_Value | 16 | 16 | 0 | 20.95 | 12.85 | 14.65 - 27.24 | 7.81 - 49.68 | 17.47 | 10.61 - 27.82 | Н/П* | Н/П* | ||||||||||
4ТM_TH1 | Abs_Value | 16 | 16 | 0 | 12.57 | 13.68 | 5.87 - 19.28 | 0.08 - 43.91 | 5.73 | 4.91 - 14.5 | Н/П* | Н/П* | ||||||||||
4ТM_TH17 | Abs_Value | 16 | 16 | 0 | 10.27 | 7.78 | 6.46 - 14.08 | 0.84 - 27.7 | 7.96 | 4.34 - 13.61 | Н/П* | Н/П* | ||||||||||
4ТM_Th17TO1 | Abs_Value | 16 | 16 | 0 | 3.66 | 3.12 | 2.13 - 5.19 | 0.05 - 10.67 | 2.76 | 1.66 - 4.3 | Н/П* | Н/П* | ||||||||||
4ТM_TH2 | Abs_Value | 16 | 16 | 0 | 7.39 | 7.76 | 3.59 - 11.2 | 0.56 - 30.18 | 4.11 | 1.81 - 11.18 | Н/П* | Н/П* | ||||||||||
4ТM_TH22 | Abs_Value | 16 | 16 | 0 | 6.38 | 5.58 | 3.64 - 9.11 | 0.12 - 17.72 | 4.12 | 2.47 - 9.31 | Н/П* | Н/П* | ||||||||||
4ТREG | Abs_Value | 16 | 16 | 0 | 2.77 | 3.73 | 0.94 - 4.59 | 0.04 - 13.02 | 1.12 | 0.55 - 2.67 | Н/П* | Н/П* | ||||||||||
4ТREG(СТАР2) | Abs_Value | 16 | 16 | 0 | 138.47 | 81.61 | 98.48 - 178.45 | 45.87 - 308.22 | 118.87 | 72.38 - 194.27 | Н/П* | Н/П* | ||||||||||
4ТREG_TH1 | Abs_Value | 16 | 16 | 0 | 0.37 | 0.5 | 0.13 - 0.62 | 0.02 - 1.73 | 0.21 | 0.07 - 0.31 | Н/П* | Н/П* | ||||||||||
4ТREG_TH17 | Abs_Value | 16 | 16 | 0 | 4.3 | 3.2 | 2.73 - 5.87 | 0.86 - 13.28 | 3.51 | 1.97 - 5.48 | Н/П* | Н/П* | ||||||||||
4ТREG_Th17TO1 | Abs_Value | 16 | 16 | 0 | 0.14 | 0.16 | 0.06 - 0.22 | 0 - 0.49 | 0.05 | 0.02 - 0.25 | Н/П* | Н/П* | ||||||||||
4ТREG_TH2 | Abs_Value | 16 | 16 | 0 | 2.72 | 1.4 | 2.03 - 3.41 | 0.32 - 6.34 | 2.86 | 1.58 - 3.38 | Н/П* | Н/П* | ||||||||||
4ТREG_TH22 | Abs_Value | 16 | 16 | 0 | 3.67 | 2.57 | 2.41 - 4.93 | 0.84 - 9.32 | 3.37 | 1.45 - 5.51 | Н/П* | Н/П* | ||||||||||
4ТЕ | Abs_Value | 16 | 16 | 0 | 12.11 | 23.09 | 0.8 - 23.43 | 0.1 - 86.7 | 1.66 | 0.64 - 8.96 | Н/П* | Н/П* | ||||||||||
4ТЕ(СТАР2) | Abs_Value | 16 | 16 | 0 | 46.28 | 52.68 | 20.47 - 72.1 | 10.54 - 179.15 | 24.72 | 18.15 - 46.09 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH1 | Abs_Value | 16 | 16 | 0 | 2.93 | 7.7 | -0.85 - 6.7 | 0 - 31.37 | 0.55 | 0.13 - 1.75 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH17 | Abs_Value | 16 | 16 | 0 | 0 | 0.01 | 0 - 0.01 | 0 - 0.02 | 0 | 0 - 0.01 | Н/П* | Н/П* | ||||||||||
4ТЕ_Th17TO1 | Abs_Value | 16 | 16 | 0 | 0.09 | 0.2 | 0 - 0.19 | 0 - 0.78 | 0.01 | 0 - 0.06 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH2 | Abs_Value | 16 | 16 | 0 | 0.25 | 0.52 | 0 - 0.51 | 0 - 2.03 | 0.05 | 0.01 - 0.17 | Н/П* | Н/П* | ||||||||||
4ТЕ_TH22 | Abs_Value | 16 | 16 | 0 | 0 | 0.01 | 0 - 0.01 | 0 - 0.02 | 0 | 0 - 0 | Н/П* | Н/П* | ||||||||||
4ТЕ+226+ | Abs_Value | 16 | 16 | 0 | 42.58 | 49.68 | 18.24 - 66.92 | 9.58 - 174.69 | 20.95 | 15.78 - 41.84 | Н/П* | Н/П* | ||||||||||
4ТЕ+39+ | Abs_Value | 16 | 16 | 0 | 9.58 | 19.21 | 0.17 - 18.99 | 0.11 - 76.01 | 2.69 | 1.1 - 6.23 | Н/П* | Н/П* | ||||||||||
4ТЕ+DR+ | Abs_Value | 16 | 16 | 0 | 23.14 | 34.36 | 6.3 - 39.97 | 1.71 - 119.56 | 11.25 | 3.25 - 19.01 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 15.74 | 18.58 | 6.63 - 24.84 | 1.05 - 77.66 | 8.83 | 6.01 - 16.42 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 2.38 | 2.93 | 0.95 - 3.82 | 0.25 - 11.49 | 1.42 | 0.72 - 2.58 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+ | Abs_Value | 16 | 16 | 0 | 28.16 | 35.29 | 10.87 - 45.46 | 4.45 - 126.54 | 12.85 | 9.84 - 22.45 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 16.67 | 19.57 | 7.08 - 26.26 | 1.62 - 67.21 | 9.04 | 4.03 - 15.46 | Н/П* | Н/П* | ||||||||||
4ТЕ+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 11.49 | 19 | 2.18 - 20.8 | 1.41 - 78.88 | 4.87 | 3.31 - 9.58 | Н/П* | Н/П* | ||||||||||
4ТЕ+TIGIT+ | Abs_Value | 16 | 16 | 0 | 13.88 | 20.94 | 3.62 - 24.14 | 2.14 - 85.88 | 6.14 | 4.09 - 12.22 | Н/П* | Н/П* | ||||||||||
4ТМ | Abs_Value | 16 | 16 | 0 | 104.08 | 71.19 | 69.2 - 138.97 | 10.27 - 315 | 108.35 | 52.94 - 121.85 | Н/П* | Н/П* | ||||||||||
8+ | Abs_Value | 16 | 16 | 0 | 483.96 | 570.83 | 204.26 - 763.67 | 14.73 - 2238.8 | 304.59 | 68.25 - 709.26 | Н/П* | Н/П* | ||||||||||
8+ (IM STAT) | Abs_Value | 16 | 16 | 0 | 609.74 | 665.61 | 283.6 - 935.89 | 16.62 - 2673.64 | 442.06 | 114.75 - 887.6 | Н/П* | Н/П* | ||||||||||
8+226+ | Abs_Value | 16 | 16 | 0 | 753.82 | 776.41 | 373.38 - 1134.26 | 86.91 - 3240.63 | 557.23 | 173.53 - 1009.04 | Н/П* | Н/П* | ||||||||||
8+39+ | Abs_Value | 16 | 16 | 0 | 96.16 | 122.44 | 36.16 - 156.15 | 2.61 - 428.13 | 46.94 | 19.91 - 114.27 | Н/П* | Н/П* | ||||||||||
8+DR+ | Abs_Value | 16 | 16 | 0 | 541.38 | 669.73 | 213.22 - 869.55 | 40.55 - 2729.41 | 332.49 | 144.84 - 628.19 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 270.21 | 320.05 | 113.39 - 427.03 | 41.92 - 1371.15 | 169.76 | 91.78 - 323.43 | Н/П* | Н/П* | ||||||||||
8+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 240.55 | 333.54 | 77.12 - 403.98 | 11.7 - 1209.08 | 116.12 | 27.43 - 225.26 | Н/П* | Н/П* | ||||||||||
8+PD-1+ | Abs_Value | 16 | 16 | 0 | 350.72 | 343.07 | 182.62 - 518.83 | 32.61 - 1231.92 | 257.6 | 106.43 - 493.01 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 110.21 | 118.56 | 52.12 - 168.3 | 9.56 - 367.72 | 50.18 | 38.78 - 140.79 | Н/П* | Н/П* | ||||||||||
8+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 240.51 | 275.68 | 105.43 - 375.59 | 17.7 - 1097.55 | 156.79 | 52.92 - 320.3 | Н/П* | Н/П* | ||||||||||
8+TIGIT+ | Abs_Value | 16 | 16 | 0 | 481.06 | 475.3 | 248.17 - 713.96 | 38.2 - 1576.95 | 282.64 | 65.8 - 759 | Н/П* | Н/П* | ||||||||||
8EMTM | Abs_Value | 16 | 16 | 0 | 107.4 | 93.5 | 61.58 - 153.21 | 2.31 - 329.24 | 89.66 | 36.53 - 145.89 | Н/П* | Н/П* | ||||||||||
8EMTM+226+ | Abs_Value | 16 | 16 | 0 | 89.77 | 87.29 | 47 - 132.55 | 1.94 - 322.53 | 62.82 | 26.16 - 124.81 | Н/П* | Н/П* | ||||||||||
8EMTM+39+ | Abs_Value | 16 | 16 | 0 | 16.13 | 17.42 | 7.6 - 24.67 | 0.51 - 52.65 | 11.57 | 1.72 - 23.43 | Н/П* | Н/П* | ||||||||||
8EMTM+DR+ | Abs_Value | 16 | 16 | 0 | 79.14 | 65.23 | 47.18 - 111.11 | 2.13 - 212.97 | 66.93 | 28.12 - 116.1 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 23.65 | 28.49 | 9.69 - 37.61 | 0.73 - 96.46 | 11.24 | 4.44 - 31.65 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 17.07 | 20.91 | 6.83 - 27.32 | 0.22 - 81.95 | 7.77 | 3.49 - 27 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+ | Abs_Value | 16 | 16 | 0 | 66.67 | 62.9 | 35.85 - 97.49 | 1.36 - 255.69 | 62.14 | 21.09 - 87.57 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 22.19 | 27.96 | 8.48 - 35.89 | 0.69 - 110.4 | 13.72 | 6.74 - 21.03 | Н/П* | Н/П* | ||||||||||
8EMTM+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 44.49 | 43.02 | 23.41 - 65.56 | 0.67 - 145.3 | 31.84 | 10.28 - 62.94 | Н/П* | Н/П* | ||||||||||
8EMTM+TIGIT+ | Abs_Value | 16 | 16 | 0 | 61.56 | 55.9 | 34.17 - 88.95 | 0.89 - 170.16 | 40.89 | 15.83 - 105.25 | Н/П* | Н/П* | ||||||||||
8NV | Abs_Value | 16 | 16 | 0 | 45.74 | 44.53 | 23.93 - 67.56 | 9.18 - 184.51 | 26.4 | 17.5 - 61.65 | Н/П* | Н/П* | ||||||||||
8NV(СТАР2) | Abs_Value | 16 | 16 | 0 | 54.54 | 70.98 | 19.76 - 89.32 | 3.34 - 298.83 | 32.85 | 16.66 - 59.43 | Н/П* | Н/П* | ||||||||||
8NV+226+ | Abs_Value | 16 | 16 | 0 | 49.02 | 69.71 | 14.87 - 83.18 | 2.97 - 293.94 | 30.66 | 15.35 - 51.92 | Н/П* | Н/П* | ||||||||||
8NV+39+ | Abs_Value | 16 | 16 | 0 | 3.23 | 3.32 | 1.6 - 4.85 | 0.06 - 10.69 | 2.17 | 0.62 - 4.34 | Н/П* | Н/П* | ||||||||||
8NV+DR+ | Abs_Value | 16 | 16 | 0 | 5.83 | 4.64 | 3.56 - 8.11 | 0.39 - 16.08 | 3.75 | 2.54 - 8.79 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 45 | 69.44 | 10.98 - 79.03 | 0.89 - 288.77 | 25.56 | 10.96 - 41.48 | Н/П* | Н/П* | ||||||||||
8NV+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 2.6 | 2.33 | 1.46 - 3.74 | 0.08 - 7.9 | 1.9 | 0.73 - 4.47 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+ | Abs_Value | 16 | 16 | 0 | 6.94 | 6.77 | 3.62 - 10.26 | 0.58 - 25.65 | 4.93 | 2.43 - 8.52 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 2.75 | 3.28 | 1.15 - 4.36 | 0.02 - 11.05 | 1.5 | 0.69 - 3.46 | Н/П* | Н/П* | ||||||||||
8NV+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 4.19 | 4.73 | 1.87 - 6.5 | 0.56 - 17.13 | 2.56 | 1.14 - 4.17 | Н/П* | Н/П* | ||||||||||
8NV+TIGIT+ | Abs_Value | 16 | 16 | 0 | 6.78 | 5.99 | 3.85 - 9.72 | 1.52 - 19.73 | 3.92 | 2.49 - 9.77 | Н/П* | Н/П* | ||||||||||
8TREG | Abs_Value | 16 | 16 | 0 | 476.38 | 546.46 | 208.61 - 744.14 | 14 - 2160.15 | 322.51 | 70.53 - 695.58 | Н/П* | Н/П* | ||||||||||
8ЕМ | Abs_Value | 16 | 16 | 0 | 101.04 | 118.3 | 43.08 - 159.01 | 2.96 - 350.98 | 40.04 | 20.01 - 173.13 | Н/П* | Н/П* | ||||||||||
8СМ | Abs_Value | 16 | 16 | 0 | 18.78 | 35.01 | 1.62 - 35.93 | 0.71 - 142.48 | 8.33 | 4.18 - 11.2 | Н/П* | Н/П* | ||||||||||
8СМ(СТАР2) | Abs_Value | 16 | 16 | 0 | 10.74 | 13.16 | 4.29 - 17.19 | 1.43 - 45.99 | 6.28 | 5.32 - 8.71 | Н/П* | Н/П* | ||||||||||
8СМ+226+ | Abs_Value | 16 | 16 | 0 | 7.26 | 7.43 | 3.62 - 10.9 | 1.17 - 27.65 | 5.09 | 4.2 - 6.31 | Н/П* | Н/П* | ||||||||||
8СМ+39+ | Abs_Value | 16 | 16 | 0 | 2.72 | 3.64 | 0.94 - 4.51 | 0.08 - 12.25 | 1.63 | 0.49 - 3.06 | Н/П* | Н/П* | ||||||||||
8СМ+DR+ | Abs_Value | 16 | 16 | 0 | 8.28 | 10.55 | 3.11 - 13.45 | 0.95 - 40.03 | 4.7 | 3.28 - 6.65 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 1.48 | 1.19 | 0.9 - 2.07 | 0.09 - 5.04 | 1.24 | 1.01 - 1.78 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 2 | 2.86 | 0.6 - 3.4 | 0.04 - 9.71 | 1 | 0.54 - 1.45 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+ | Abs_Value | 16 | 16 | 0 | 7.26 | 9.89 | 2.42 - 12.11 | 1.14 - 36.67 | 3.64 | 2.17 - 5.64 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 0.8 | 0.82 | 0.4 - 1.2 | 0.1 - 3.03 | 0.43 | 0.35 - 0.86 | Н/П* | Н/П* | ||||||||||
8СМ+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 6.46 | 9.66 | 1.73 - 11.2 | 0.84 - 35.27 | 2.98 | 1.75 - 5.14 | Н/П* | Н/П* | ||||||||||
8СМ+TIGIT+ | Abs_Value | 16 | 16 | 0 | 8.46 | 12.34 | 2.41 - 14.5 | 0.93 - 43.35 | 4.12 | 2.65 - 6.7 | Н/П* | Н/П* | ||||||||||
8ТЕ | Abs_Value | 16 | 16 | 0 | 501.34 | 697.27 | 159.67 - 843 | 27.81 - 2935.15 | 315.6 | 112.05 - 556.57 | Н/П* | Н/П* | ||||||||||
8ТЕ(СТАР2) | Abs_Value | 16 | 16 | 0 | 685.6 | 784.62 | 301.14 - 1070.06 | 35.46 - 3213.82 | 506 | 156.46 - 979.83 | Н/П* | Н/П* | ||||||||||
8ТЕ+226+ | Abs_Value | 16 | 16 | 0 | 605.32 | 757.57 | 234.11 - 976.53 | 34.55 - 3154.74 | 352.23 | 150.77 - 781.62 | Н/П* | Н/П* | ||||||||||
8ТЕ+39+ | Abs_Value | 16 | 16 | 0 | 73.58 | 111.95 | 18.72 - 128.44 | 1.13 - 386.23 | 25.52 | 8.98 - 82.36 | Н/П* | Н/П* | ||||||||||
8ТЕ+DR+ | Abs_Value | 16 | 16 | 0 | 447.63 | 655.54 | 126.41 - 768.84 | 20.58 - 2669.82 | 240.49 | 106.37 - 478.6 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT- | Abs_Value | 16 | 16 | 0 | 199.55 | 318.56 | 43.46 - 355.65 | 9.04 - 1323.33 | 86.53 | 44.16 - 243.13 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1-TIGIT+ | Abs_Value | 16 | 16 | 0 | 216.44 | 317.94 | 60.65 - 372.23 | 9.38 - 1190.46 | 94.42 | 24.2 - 195.52 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+ | Abs_Value | 16 | 16 | 0 | 269.6 | 303.31 | 120.98 - 418.23 | 16.39 - 1104.9 | 170.5 | 66.27 - 358.79 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT- | Abs_Value | 16 | 16 | 0 | 84.52 | 100.53 | 35.26 - 133.78 | 5.34 - 353.82 | 34.82 | 24.87 - 116.83 | Н/П* | Н/П* | ||||||||||
8ТЕ+PD-1+TIGIT+ | Abs_Value | 16 | 16 | 0 | 185.09 | 244.63 | 65.22 - 304.95 | 11.05 - 987.9 | 106.95 | 40.06 - 235.62 | Н/П* | Н/П* | ||||||||||
8ТЕ+TIGIT+ | Abs_Value | 16 | 16 | 0 | 401.52 | 438.75 | 186.54 - 616.51 | 20.43 - 1536.67 | 234.01 | 54.74 - 587.2 | Н/П* | Н/П* | ||||||||||
8ТМ | Abs_Value | 16 | 16 | 0 | 43.72 | 58.64 | 14.98 - 72.45 | 0.57 - 244.32 | 21.85 | 10.88 - 60.22 | Н/П* | Н/П* | ||||||||||
TREG_CM | Abs_Value | 16 | 16 | 0 | 1.83 | 1.04 | 1.32 - 2.34 | 0.19 - 3.86 | 1.63 | 1.35 - 2.2 | Н/П* | Н/П* | ||||||||||
TREG_EMTM | Abs_Value | 16 | 16 | 0 | 19.2 | 16.73 | 11 - 27.4 | 3.24 - 57.99 | 16.19 | 6.39 - 22.43 | Н/П* | Н/П* | ||||||||||
TREG_NV | Abs_Value | 16 | 16 | 0 | 2.59 | 2.52 | 1.35 - 3.82 | 0.22 - 7.96 | 1.22 | 0.91 - 3.92 | Н/П* | Н/П* | ||||||||||
TREG_TE | Abs_Value | 16 | 16 | 0 | 4.87 | 8.07 | 0.92 - 8.82 | 0.35 - 33.62 | 2.28 | 1.42 - 4.96 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT- | Abs_Value | 16 | 16 | 0 | 1.77 | 1.68 | 0.95 - 2.59 | 0.09 - 5.76 | 1.37 | 0.45 - 2.28 | Н/П* | Н/П* | ||||||||||
TREG+226-TIGIT+ | Abs_Value | 16 | 16 | 0 | 6.18 | 6.1 | 3.2 - 9.17 | 0.38 - 18.95 | 4.4 | 1.76 - 8.88 | Н/П* | Н/П* | ||||||||||
TREG+226+ | Abs_Value | 16 | 16 | 0 | 20.48 | 17.47 | 11.92 - 29.04 | 3.74 - 64.06 | 15.48 | 7.87 - 26.26 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT- | Abs_Value | 16 | 16 | 0 | 2.6 | 1.7 | 1.77 - 3.44 | 0.37 - 5.6 | 2.62 | 0.91 - 3.75 | Н/П* | Н/П* | ||||||||||
TREG+226+TIGIT+ | Abs_Value | 16 | 16 | 0 | 17.88 | 16.73 | 9.68 - 26.08 | 3.37 - 58.46 | 11.88 | 6.05 - 24.33 | Н/П* | Н/П* | ||||||||||
TREG+39+ | Abs_Value | 16 | 16 | 0 | 20.12 | 20.89 | 9.88 - 30.35 | 3.52 - 76.71 | 12.83 | 6.64 - 23.81 | Н/П* | Н/П* | ||||||||||
TREG+DR+ | Abs_Value | 16 | 16 | 0 | 18.52 | 17.96 | 9.72 - 27.32 | 3.45 - 67.02 | 16.88 | 6.22 - 20.21 | Н/П* | Н/П* | ||||||||||
TREG+PD-1+ | Abs_Value | 16 | 16 | 0 | 13.74 | 14.23 | 6.77 - 20.71 | 2.61 - 48.13 | 9.94 | 4.29 - 14.6 | Н/П* | Н/П* | ||||||||||
TREG+TIGIT+ | Abs_Value | 16 | 16 | 0 | 24.06 | 21.65 | 13.46 - 34.67 | 3.75 - 77.23 | 18.29 | 7.78 - 31.58 | Н/П* | Н/П* |
В таблицах столбцы No- для тех, у кого не развилось cGVHD, Yes - у кого развилось
# Те же статистики
statistics <- list(
`_Количество субъектов` = ~length(.x) %>% as.character(),
`_Количество (есть данные)` = ~sum(!is.na(.x)) %>% as.character(),
`_Нет данных` = ~sum(is.na(.x)) %>% as.character(),
`_Ср. знач.` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", mean(.x, na.rm = TRUE) %>% round(2) %>% as.character()),
`_Станд. отклон.` = ~ifelse(sum(!is.na(.x)) < 3, "Н/П*", sd(.x, na.rm = TRUE) %>% round(2) %>% as.character()),
`_95% ДИ для среднего` = ~{
n <- sum(!is.na(.x))
ifelse(n < 3, "Н/П*",
paste0(round(mean(.x, na.rm = TRUE) - 1.96 * sd(.x, na.rm = TRUE) / sqrt(n), 2), " - ", round(mean(.x, na.rm = TRUE) + 1.96 * sd(.x, na.rm = TRUE) / sqrt(n), 2))
)
},
`_мин. - макс.` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", paste0(min(.x, na.rm = TRUE) %>% round(2), " - ", max(.x, na.rm = TRUE) %>% round(2))),
`_Медиана` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", median(.x, na.rm = TRUE) %>% round(2) %>% as.character()),
`_Q1 - Q3` = ~ifelse(sum(!is.na(.x)) == 0, "Н/П*", paste0(quantile(.x, 0.25, na.rm = TRUE) %>% round(2), " - ", quantile(.x, 0.75, na.rm = TRUE) %>% round(2)))
)
# Фильтруем данные только для +90 дней
AI_Tcells_90 <- AI_Tcells_filtered %>%
filter(Analysis_day == "+90")
# Функция для t-теста
t_test_wrapper <- function(data, var) {
n_yes <- sum(!is.na(data$Abs_Value[data$cGVHD_present == "Yes"]))
n_no <- sum(!is.na(data$Abs_Value[data$cGVHD_present == "No"]))
if(n_yes < 3 || n_no < 3) {
return("Н/П*")
}
test_result <- try(
t.test(Abs_Value ~ cGVHD_present, data = data)$p.value,
silent = TRUE
)
if(inherits(test_result, "try-error")) {
return("Ошибка")
}
return(as.character(round(test_result, 4)))
}
# Собираем p-values только для данных 90-го дня
p_values_df_90 <- AI_Tcells_90 %>%
group_by(Сell_population) %>%
summarise(
p_value = t_test_wrapper(cur_data(), Abs_Value),
.groups = "drop"
)
# Корректируем p-values
p_values_df_90 <- p_values_df_90 %>%
mutate(
adj_p_value = p_value
)
# Находим индексы числовых p-values
numeric_indices <- !p_values_df_90$p_value %in% c("Н/П*", "Ошибка")
if(sum(numeric_indices) > 0) {
numeric_p_values <- as.numeric(p_values_df_90$p_value[numeric_indices])
adj_p_values <- p.adjust(numeric_p_values, method = "BH")
p_values_df_90$adj_p_value[numeric_indices] <- as.character(round(adj_p_values, 4))
}
# Создаем финальную таблицу
result_90 <- AI_Tcells_90 %>%
select(`Сell_population`, `cGVHD_present`, Abs_Value) %>%
group_by(`Сell_population`, `cGVHD_present`) %>%
summarize(across(Abs_Value, statistics), .groups = "drop") %>%
pivot_longer(cols = -c(`Сell_population`, `cGVHD_present`)) %>%
separate(name, into = c("Variable", "Statistics"), sep = "__") %>%
pivot_wider(names_from = c(cGVHD_present, Statistics), values_from = value) %>%
# Присоединяем p-values
left_join(p_values_df_90, by = c("Сell_population")) %>%
rename(
"t-test, p-value" = p_value,
"t-test, adj p-value (BH)" = adj_p_value
) %>%
# Создаём финальную таблицу
arrange(Сell_population) %>%
flextable() %>%
theme_box() %>%
align(align = "center", part = "all")
# Выводим таблицу
result_90
Сell_population | Variable | No_Количество субъектов | No_Количество (есть данные) | No_Нет данных | No_Ср. знач. | No_Станд. отклон. | No_95% ДИ для среднего | No_мин. - макс. | No_Медиана | No_Q1 - Q3 | Yes_Количество субъектов | Yes_Количество (есть данные) | Yes_Нет данных | Yes_Ср. знач. | Yes_Станд. отклон. | Yes_95% ДИ для среднего | Yes_мин. - макс. | Yes_Медиана | Yes_Q1 - Q3 | t-test, p-value | t-test, adj p-value (BH) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
4_TFH | Abs_Value | 39 | 39 | 0 | 16.33 | 13.43 | 12.11 - 20.55 | 0 - 61.09 | 13.26 | 8.06 - 22.35 | 28 | 28 | 0 | 14.42 | 12.25 | 9.88 - 18.96 | 1.1 - 45.51 | 10.81 | 4.76 - 18.65 | 0.5483 | 0.7484 |
4_TH1 | Abs_Value | 39 | 39 | 0 | 35.1 | 96.74 | 4.74 - 65.47 | 0.16 - 608.2 | 10.47 | 5.84 - 24.35 | 28 | 28 | 0 | 17.24 | 24.14 | 8.3 - 26.19 | 0.03 - 113.81 | 9.26 | 4.29 - 17.68 | 0.2747 | 0.6696 |
4_TH17 | Abs_Value | 39 | 39 | 0 | 13.84 | 8.71 | 11.11 - 16.57 | 0.02 - 34.84 | 12.75 | 6.74 - 18.73 | 28 | 28 | 0 | 13.49 | 9.77 | 9.87 - 17.11 | 0.86 - 40.22 | 11.94 | 6.64 - 20.16 | 0.8803 | 0.9621 |
4_Th17TO1 | Abs_Value | 39 | 39 | 0 | 3.39 | 3.17 | 2.4 - 4.39 | 0.03 - 17.49 | 2.3 | 1.43 - 4.6 | 28 | 28 | 0 | 3.75 | 4.89 | 1.93 - 5.56 | 0.05 - 18.77 | 2.09 | 0.78 - 3.94 | 0.7375 | 0.8959 |
4_TH2 | Abs_Value | 39 | 39 | 0 | 13.04 | 22.22 | 6.06 - 20.01 | 0.02 - 143.45 | 8.78 | 5.17 - 13.6 | 28 | 28 | 0 | 13.67 | 9.99 | 9.97 - 17.37 | 0.58 - 37.81 | 10.16 | 6.22 - 19.3 | 0.8754 | 0.9621 |
4_TH22 | Abs_Value | 39 | 39 | 0 | 3.91 | 3.18 | 2.91 - 4.91 | 0 - 13.92 | 3.12 | 1.51 - 5.85 | 28 | 28 | 0 | 4.25 | 3.86 | 2.82 - 5.68 | 0.02 - 14.86 | 3.06 | 1.61 - 5.72 | 0.7032 | 0.8671 |
4+ | Abs_Value | 39 | 39 | 0 | 70.84 | 76.56 | 46.81 - 94.87 | 0.01 - 430.92 | 59.43 | 20.66 - 92.9 | 28 | 28 | 0 | 83.71 | 46.4 | 66.52 - 100.89 | 1.65 - 194.52 | 81.98 | 48.2 - 121.66 | 0.3964 | 0.6762 |
4+ (IM STAT) | Abs_Value | 39 | 39 | 0 | 65.93 | 72.58 | 43.14 - 88.71 | 0 - 397.77 | 47.44 | 19.37 - 82.94 | 28 | 28 | 0 | 74.78 | 44.66 | 58.24 - 91.32 | 2.77 - 186.76 | 77.26 | 37.17 - 96.8 | 0.5398 | 0.7484 |
4+226+ | Abs_Value | 39 | 39 | 0 | 155.71 | 179.73 | 99.3 - 212.12 | 0.31 - 1046.46 | 128.08 | 68.58 - 160.33 | 28 | 28 | 0 | 132.45 | 73.4 | 105.26 - 159.64 | 16.89 - 269.89 | 131.07 | 76.06 - 166.98 | 0.4698 | 0.6986 |
4+39+ | Abs_Value | 39 | 39 | 0 | 39.48 | 31.48 | 29.6 - 49.36 | 0.07 - 135.08 | 37.22 | 19.19 - 54.81 | 28 | 28 | 0 | 40.21 | 33.36 | 27.86 - 52.57 | 0.49 - 110.79 | 34.79 | 9.36 - 63.23 | 0.9278 | 0.9731 |
4+DR+ | Abs_Value | 39 | 39 | 0 | 102.8 | 170.68 | 49.23 - 156.37 | 0.05 - 960.16 | 65.32 | 31.43 - 87.28 | 28 | 28 | 0 | 64.77 | 56.51 | 43.84 - 85.71 | 4.16 - 250.67 | 51.29 | 24.28 - 82.42 | 0.2011 | 0.6696 |
4+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 48.64 | 34 | 37.97 - 59.31 | 0.03 - 131.28 | 34.59 | 25.53 - 75.58 | 28 | 28 | 0 | 55.29 | 44.79 | 38.69 - 71.88 | 6.67 - 166.24 | 41.71 | 22.29 - 76.75 | 0.5119 | 0.73 |
4+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 8.16 | 24.25 | 0.55 - 15.77 | 0 - 154.31 | 3.78 | 1.76 - 6.59 | 28 | 28 | 0 | 4.87 | 3.39 | 3.61 - 6.12 | 0.25 - 12.65 | 3.76 | 2.29 - 7.19 | 0.4071 | 0.6762 |
4+PD-1+ | Abs_Value | 39 | 39 | 0 | 108.13 | 148.15 | 61.64 - 154.63 | 0.33 - 789.05 | 77.82 | 46.08 - 97.71 | 28 | 28 | 0 | 82.56 | 62.59 | 59.37 - 105.74 | 7.01 - 256.14 | 70.45 | 36.32 - 110.92 | 0.3389 | 0.6696 |
4+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 55.79 | 53.07 | 39.14 - 72.45 | 0.28 - 262.81 | 35.44 | 26.29 - 61.74 | 28 | 28 | 0 | 47.04 | 40.36 | 32.09 - 61.98 | 3.7 - 176.04 | 35.9 | 21.62 - 63.3 | 0.4459 | 0.6834 |
4+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 52.34 | 100.95 | 20.66 - 84.03 | 0.05 - 526.23 | 28.49 | 18 - 44.4 | 28 | 28 | 0 | 35.52 | 29.85 | 24.47 - 46.58 | 3.31 - 119.05 | 23.88 | 15.59 - 49.99 | 0.3309 | 0.6696 |
4+TIGIT+ | Abs_Value | 39 | 39 | 0 | 60.51 | 121.07 | 22.51 - 98.51 | 0.05 - 680.54 | 31.37 | 20.51 - 50.09 | 28 | 28 | 0 | 40.39 | 31.42 | 28.75 - 52.03 | 4.89 - 130.02 | 28.02 | 20.05 - 55.79 | 0.3264 | 0.6696 |
4NV | Abs_Value | 39 | 39 | 0 | 17.03 | 15.12 | 12.28 - 21.78 | 0 - 55.9 | 12.73 | 6.44 - 21.38 | 28 | 28 | 0 | 28.77 | 26.38 | 19 - 38.55 | 3.15 - 110.75 | 18.27 | 8.39 - 39.7 | 0.0404 | 0.6696 |
4NV(СТАР2) | Abs_Value | 39 | 39 | 0 | 15.95 | 15.14 | 11.2 - 20.7 | 0 - 54 | 10.42 | 6.42 - 18.05 | 28 | 28 | 0 | 26.63 | 24.08 | 17.71 - 35.55 | 4.36 - 99.11 | 18.69 | 7.91 - 35.34 | 0.0444 | 0.6696 |
4NV_TH1 | Abs_Value | 39 | 39 | 0 | 1.27 | 1.37 | 0.84 - 1.7 | 0 - 6.02 | 0.92 | 0.31 - 1.7 | 28 | 28 | 0 | 1.99 | 2.02 | 1.24 - 2.74 | 0.01 - 7.62 | 1.39 | 0.42 - 2.94 | 0.1094 | 0.6696 |
4NV_TH17 | Abs_Value | 39 | 39 | 0 | 0.59 | 0.58 | 0.41 - 0.77 | 0 - 2.9 | 0.41 | 0.18 - 0.81 | 28 | 28 | 0 | 0.92 | 0.76 | 0.64 - 1.2 | 0.12 - 3.24 | 0.68 | 0.45 - 1.19 | 0.0582 | 0.6696 |
4NV_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.11 | 0.12 | 0.08 - 0.15 | 0 - 0.43 | 0.07 | 0.02 - 0.17 | 28 | 28 | 0 | 0.21 | 0.25 | 0.12 - 0.3 | 0.01 - 1.08 | 0.12 | 0.04 - 0.24 | 0.0737 | 0.6696 |
4NV_TH2 | Abs_Value | 39 | 39 | 0 | 1.99 | 2.41 | 1.23 - 2.74 | 0 - 11.34 | 1.09 | 0.62 - 2.33 | 28 | 28 | 0 | 4.1 | 4.56 | 2.41 - 5.79 | 0.14 - 20.02 | 2.86 | 1.01 - 5.49 | 0.0312 | 0.6696 |
4NV_TH22 | Abs_Value | 39 | 39 | 0 | 0.05 | 0.08 | 0.03 - 0.08 | 0 - 0.32 | 0.02 | 0.01 - 0.06 | 28 | 28 | 0 | 0.09 | 0.12 | 0.05 - 0.14 | 0 - 0.55 | 0.04 | 0.01 - 0.15 | 0.1106 | 0.6696 |
4NV+226+ | Abs_Value | 39 | 39 | 0 | 13.74 | 13.09 | 9.63 - 17.84 | 0 - 43.3 | 9.21 | 6.11 - 15.8 | 28 | 28 | 0 | 23.13 | 21.19 | 15.28 - 30.98 | 3.48 - 85.04 | 16.11 | 7.06 - 29.98 | 0.044 | 0.6696 |
4NV+39+ | Abs_Value | 39 | 39 | 0 | 0.7 | 0.89 | 0.42 - 0.98 | 0 - 3.98 | 0.4 | 0.1 - 0.87 | 28 | 28 | 0 | 0.98 | 0.98 | 0.61 - 1.34 | 0.01 - 4.69 | 0.75 | 0.48 - 1.13 | 0.2396 | 0.6696 |
4NV+DR+ | Abs_Value | 39 | 39 | 0 | 1.96 | 3.25 | 0.94 - 2.98 | 0 - 17.28 | 0.83 | 0.41 - 1.75 | 28 | 28 | 0 | 1.75 | 1.95 | 1.03 - 2.47 | 0.25 - 10.14 | 1.16 | 0.7 - 1.82 | 0.7485 | 0.9026 |
4NV+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 14.19 | 14.36 | 9.69 - 18.7 | 0 - 47.46 | 9.27 | 4.44 - 17.37 | 28 | 28 | 0 | 24.61 | 23.7 | 15.84 - 33.39 | 2.32 - 98.02 | 16.98 | 6.11 - 33.64 | 0.0448 | 0.6696 |
4NV+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.46 | 0.79 | 0.22 - 0.71 | 0 - 4.58 | 0.26 | 0.11 - 0.41 | 28 | 28 | 0 | 0.61 | 0.55 | 0.4 - 0.81 | 0.07 - 2.14 | 0.44 | 0.25 - 0.7 | 0.3928 | 0.6762 |
4NV+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 0.87 | 1.14 | 0.51 - 1.23 | 0 - 4.56 | 0.35 | 0.23 - 0.96 | 28 | 28 | 0 | 0.93 | 0.76 | 0.65 - 1.21 | 0.1 - 3.04 | 0.72 | 0.34 - 1.24 | 0.7927 | 0.9228 |
4NV+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.42 | 0.56 | 0.25 - 0.6 | 0 - 2.84 | 0.19 | 0.08 - 0.57 | 28 | 28 | 0 | 0.48 | 0.35 | 0.35 - 0.61 | 0.05 - 1.27 | 0.4 | 0.23 - 0.62 | 0.5964 | 0.7825 |
4NV+PD1+ | Abs_Value | 39 | 39 | 0 | 1.29 | 1.54 | 0.81 - 1.77 | 0 - 6.69 | 0.63 | 0.33 - 1.84 | 28 | 28 | 0 | 1.41 | 0.95 | 1.06 - 1.76 | 0.25 - 3.76 | 1.16 | 0.64 - 1.95 | 0.6939 | 0.8621 |
4NV+TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.88 | 1.11 | 0.54 - 1.23 | 0 - 5.34 | 0.5 | 0.24 - 1.04 | 28 | 28 | 0 | 1.08 | 0.76 | 0.8 - 1.37 | 0.19 - 3.42 | 0.91 | 0.5 - 1.39 | 0.3839 | 0.6762 |
4ЕМ | Abs_Value | 39 | 39 | 0 | 29.18 | 89.5 | 1.09 - 57.27 | 0.01 - 428.8 | 3.42 | 0.63 - 16.48 | 28 | 28 | 0 | 7.64 | 17.2 | 1.27 - 14.01 | 0 - 67.92 | 0.8 | 0.19 - 3.72 | 0.1502 | 0.6696 |
4ЕМ_TH1 | Abs_Value | 39 | 39 | 0 | 11.29 | 43.51 | -2.37 - 24.94 | 0 - 267.92 | 1.06 | 0.16 - 3.75 | 28 | 28 | 0 | 1.94 | 5.86 | -0.23 - 4.11 | 0 - 30.53 | 0.2 | 0.03 - 0.92 | 0.1925 | 0.6696 |
4ЕМ_TH17 | Abs_Value | 39 | 39 | 0 | 0.07 | 0.19 | 0.01 - 0.13 | 0 - 0.9 | 0.01 | 0 - 0.03 | 28 | 28 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.15 | 0 | 0 - 0.01 | 0.0572 | 0.6696 |
4ЕМ_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.29 | 0.88 | 0.01 - 0.56 | 0 - 5.46 | 0.04 | 0.01 - 0.32 | 28 | 28 | 0 | 0.04 | 0.08 | 0.01 - 0.07 | 0 - 0.41 | 0.01 | 0 - 0.04 | 0.0894 | 0.6696 |
4ЕМ_TH2 | Abs_Value | 39 | 39 | 0 | 3.8 | 21.09 | -2.81 - 10.42 | 0 - 131.99 | 0.08 | 0.02 - 0.43 | 28 | 28 | 0 | 0.3 | 0.62 | 0.07 - 0.53 | 0 - 2.67 | 0.03 | 0.01 - 0.2 | 0.3066 | 0.6696 |
4ЕМ_TH22 | Abs_Value | 39 | 39 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.15 | 0 | 0 - 0 | 28 | 28 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.05 | 0 | 0 - 0 | 0.3268 | 0.6696 |
4ЕМ+226+ | Abs_Value | 39 | 39 | 0 | 85.97 | 111.51 | 50.98 - 120.97 | 0.28 - 553.6 | 60.55 | 31.84 - 87.48 | 28 | 28 | 0 | 61.27 | 45.72 | 44.34 - 78.21 | 2.92 - 184.9 | 61.09 | 24.67 - 85.82 | 0.2184 | 0.6696 |
4ЕМ+39+ | Abs_Value | 39 | 39 | 0 | 23.58 | 18.88 | 17.65 - 29.5 | 0.07 - 70.57 | 22.61 | 9.99 - 38 | 28 | 28 | 0 | 21.36 | 18.22 | 14.61 - 28.11 | 0.36 - 65.22 | 19.28 | 3.74 - 34.53 | 0.6308 | 0.8082 |
4ЕМ+DR+ | Abs_Value | 39 | 39 | 0 | 64.34 | 103.15 | 31.97 - 96.71 | 0.05 - 497.18 | 41.66 | 22.69 - 54.93 | 28 | 28 | 0 | 39.41 | 37.3 | 25.59 - 53.22 | 1.61 - 158.94 | 31.55 | 12.09 - 55.55 | 0.1711 | 0.6696 |
4ЕМ+PD1-TIGIT- | Abs_Value | 39 | 39 | 0 | 17.15 | 17.92 | 11.53 - 22.78 | 0.02 - 72.04 | 10.23 | 5.61 - 20.32 | 28 | 28 | 0 | 13.15 | 14.56 | 7.75 - 18.54 | 0.12 - 53.88 | 6.67 | 4.26 - 15.63 | 0.3174 | 0.6696 |
4ЕМ+PD1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 3.48 | 10.15 | 0.29 - 6.66 | 0 - 64.16 | 1.27 | 0.67 - 2.64 | 28 | 28 | 0 | 1.74 | 1.51 | 1.18 - 2.3 | 0.03 - 5.22 | 1.22 | 0.61 - 2.92 | 0.2989 | 0.6696 |
4ЕМ+PD1+ | Abs_Value | 39 | 39 | 0 | 68.62 | 97.13 | 38.13 - 99.1 | 0.31 - 488.16 | 42.29 | 29.92 - 67.94 | 28 | 28 | 0 | 49.55 | 43.2 | 33.55 - 65.55 | 2.85 - 169.81 | 41.27 | 18.21 - 65.64 | 0.2824 | 0.6696 |
4ЕМ+PD1+TIGIT- | Abs_Value | 39 | 39 | 0 | 36.22 | 35.42 | 25.1 - 47.33 | 0.26 - 163.47 | 25.02 | 16.2 - 42.8 | 28 | 28 | 0 | 29.95 | 28.72 | 19.32 - 40.59 | 1.55 - 118.87 | 21.16 | 10.76 - 39.53 | 0.4278 | 0.6834 |
4ЕМ+PD1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 32.4 | 66.32 | 11.58 - 53.22 | 0.05 - 343.46 | 16.95 | 9.28 - 23.66 | 28 | 28 | 0 | 19.6 | 19.73 | 12.29 - 26.9 | 1.3 - 92.73 | 14.3 | 6.25 - 25.74 | 0.2611 | 0.6696 |
4ЕМ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 35.88 | 73.29 | 12.88 - 58.88 | 0.05 - 349.01 | 18.54 | 10.11 - 26.96 | 28 | 28 | 0 | 21.34 | 20.59 | 13.71 - 28.97 | 1.44 - 97.96 | 18.46 | 6.9 - 26.92 | 0.2457 | 0.6696 |
4ЕМTM | Abs_Value | 39 | 39 | 0 | 89.25 | 112.7 | 53.88 - 124.62 | 0.33 - 560.51 | 61.41 | 33.6 - 92.27 | 28 | 28 | 0 | 64.44 | 48.25 | 46.57 - 82.31 | 3.5 - 201.17 | 63.48 | 25.56 - 91.84 | 0.225 | 0.6696 |
4СМ | Abs_Value | 39 | 39 | 0 | 31.42 | 22.37 | 24.4 - 38.44 | 0 - 119.97 | 27.94 | 16.69 - 46.26 | 28 | 28 | 0 | 40.08 | 23.5 | 31.38 - 48.79 | 5.35 - 88.59 | 43.11 | 17.54 - 53.18 | 0.1344 | 0.6696 |
4СМ(СТАР2) | Abs_Value | 39 | 39 | 0 | 30.02 | 22.79 | 22.87 - 37.17 | 0 - 133.51 | 26.43 | 16.63 - 38.84 | 28 | 28 | 0 | 32.97 | 19.84 | 25.62 - 40.32 | 1.94 - 67.99 | 34.65 | 16.28 - 44.77 | 0.5747 | 0.7633 |
4СМ_TH1 | Abs_Value | 39 | 39 | 0 | 1.56 | 2.53 | 0.76 - 2.35 | 0 - 15.41 | 1.1 | 0.34 - 1.69 | 28 | 28 | 0 | 1.57 | 1.47 | 1.03 - 2.12 | 0 - 4.36 | 0.9 | 0.36 - 2.7 | 0.9785 | 0.9845 |
4СМ_TH17 | Abs_Value | 39 | 39 | 0 | 5.03 | 3.89 | 3.81 - 6.25 | 0 - 15.87 | 4.24 | 1.91 - 7.32 | 28 | 28 | 0 | 6.77 | 5.73 | 4.65 - 8.89 | 0.22 - 20.07 | 4.4 | 2 - 10.07 | 0.17 | 0.6696 |
4СМ_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.38 | 0.57 | 0.21 - 0.56 | 0 - 3.07 | 0.24 | 0.06 - 0.41 | 28 | 28 | 0 | 0.55 | 0.73 | 0.28 - 0.82 | 0.03 - 3.05 | 0.25 | 0.12 - 0.65 | 0.3224 | 0.6696 |
4СМ_TH2 | Abs_Value | 39 | 39 | 0 | 3.18 | 2.55 | 2.38 - 3.98 | 0 - 11.68 | 2.61 | 1.48 - 4.55 | 28 | 28 | 0 | 5.02 | 4.33 | 3.42 - 6.63 | 0.29 - 18.6 | 4.09 | 1.54 - 8.19 | 0.0505 | 0.6696 |
4СМ_TH22 | Abs_Value | 39 | 39 | 0 | 0.53 | 0.65 | 0.33 - 0.74 | 0 - 3.29 | 0.32 | 0.1 - 0.69 | 28 | 28 | 0 | 0.85 | 0.79 | 0.56 - 1.14 | 0.01 - 2.75 | 0.79 | 0.19 - 1.1 | 0.0902 | 0.6696 |
4СМ+226+ | Abs_Value | 39 | 39 | 0 | 27.75 | 21.33 | 21.06 - 34.45 | 0 - 125.07 | 23.75 | 15.53 - 36.02 | 28 | 28 | 0 | 30.78 | 18.69 | 23.86 - 37.71 | 1.86 - 63.84 | 32.53 | 15.09 - 40.76 | 0.5396 | 0.7484 |
4СМ+39+ | Abs_Value | 39 | 39 | 0 | 10.35 | 10.02 | 7.2 - 13.49 | 0 - 49.38 | 9.36 | 1.53 - 13.97 | 28 | 28 | 0 | 12.32 | 11.87 | 7.92 - 16.71 | 0.01 - 39.63 | 9.41 | 1.22 - 17.71 | 0.479 | 0.701 |
4СМ+DR+ | Abs_Value | 39 | 39 | 0 | 14.08 | 20.69 | 7.59 - 20.58 | 0 - 127.35 | 9.85 | 5.25 - 13.14 | 28 | 28 | 0 | 11.9 | 10.78 | 7.91 - 15.89 | 0.25 - 41.83 | 8.12 | 3.91 - 16.05 | 0.5771 | 0.7633 |
4СМ+PD1-TIGIT- | Abs_Value | 39 | 39 | 0 | 9.47 | 6.39 | 7.46 - 11.47 | 0 - 23.26 | 7.52 | 5.37 - 13.64 | 28 | 28 | 0 | 11.96 | 10.31 | 8.14 - 15.78 | 0.12 - 41.2 | 8.6 | 4.25 - 18.41 | 0.264 | 0.6696 |
4СМ+PD1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 1.44 | 2.08 | 0.78 - 2.09 | 0 - 12.64 | 0.77 | 0.45 - 2.01 | 28 | 28 | 0 | 1.41 | 1.22 | 0.96 - 1.86 | 0.01 - 4.72 | 1.1 | 0.6 - 1.79 | 0.9483 | 0.9731 |
4СМ+PD1+ | Abs_Value | 39 | 39 | 0 | 19.12 | 18.7 | 13.25 - 24.99 | 0 - 111.86 | 16.09 | 9.77 - 23.86 | 28 | 28 | 0 | 19.6 | 14.8 | 14.12 - 25.08 | 0.46 - 61.96 | 17.76 | 10.26 - 23.57 | 0.9061 | 0.9731 |
4СМ+PD1+TIGIT- | Abs_Value | 39 | 39 | 0 | 8.47 | 5.96 | 6.6 - 10.34 | 0 - 23.93 | 7.21 | 4.23 - 13.21 | 28 | 28 | 0 | 8.74 | 6.04 | 6.5 - 10.98 | 0.31 - 24.42 | 8.55 | 5.14 - 11.06 | 0.855 | 0.9574 |
4СМ+PD1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 10.65 | 14.71 | 6.04 - 15.27 | 0 - 90.89 | 7.63 | 3.58 - 11.64 | 28 | 28 | 0 | 10.86 | 9.95 | 7.18 - 14.55 | 0.15 - 37.55 | 8.88 | 5.08 - 12.27 | 0.9441 | 0.9731 |
4СМ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 12.09 | 16.62 | 6.87 - 17.31 | 0 - 103.53 | 9 | 4.03 - 13.68 | 28 | 28 | 0 | 12.28 | 10.32 | 8.45 - 16.1 | 0.27 - 38.44 | 10.69 | 5.63 - 14.57 | 0.9553 | 0.9731 |
4ТM_TH1 | Abs_Value | 39 | 39 | 0 | 12.66 | 19.35 | 6.58 - 18.73 | 0.14 - 107.61 | 5.15 | 2.95 - 13.84 | 28 | 28 | 0 | 9.75 | 16.05 | 3.8 - 15.69 | 0.01 - 69.74 | 3.11 | 1.28 - 9.12 | 0.5047 | 0.7261 |
4ТM_TH17 | Abs_Value | 39 | 39 | 0 | 7.59 | 5.69 | 5.8 - 9.37 | 0.02 - 20.47 | 5.91 | 3.82 - 10.49 | 28 | 28 | 0 | 5.4 | 4.24 | 3.83 - 6.97 | 0.07 - 17.72 | 4.87 | 2.86 - 7.51 | 0.0761 | 0.6696 |
4ТM_Th17TO1 | Abs_Value | 39 | 39 | 0 | 2.19 | 1.71 | 1.65 - 2.72 | 0.03 - 6.88 | 1.88 | 0.98 - 3.01 | 28 | 28 | 0 | 2.64 | 3.74 | 1.26 - 4.02 | 0 - 13.42 | 1.26 | 0.4 - 2.99 | 0.5522 | 0.7484 |
4ТM_TH2 | Abs_Value | 39 | 39 | 0 | 3.2 | 3.01 | 2.26 - 4.15 | 0.02 - 13.03 | 2.17 | 1.45 - 3.93 | 28 | 28 | 0 | 3.69 | 4.82 | 1.91 - 5.48 | 0.07 - 25.5 | 2.9 | 0.95 - 4.16 | 0.6371 | 0.81 |
4ТM_TH22 | Abs_Value | 39 | 39 | 0 | 3.03 | 2.8 | 2.15 - 3.91 | 0 - 11.23 | 1.9 | 1.07 - 4.73 | 28 | 28 | 0 | 2.99 | 3.07 | 1.85 - 4.12 | 0 - 11.35 | 2.21 | 0.77 - 4.02 | 0.9515 | 0.9731 |
4ТREG | Abs_Value | 39 | 39 | 0 | 1.24 | 1.42 | 0.79 - 1.69 | 0 - 5.79 | 0.69 | 0.23 - 1.75 | 28 | 28 | 0 | 2.41 | 6.03 | 0.18 - 4.64 | 0.03 - 32.72 | 1.27 | 0.48 - 2.01 | 0.3225 | 0.6696 |
4ТREG(СТАР2) | Abs_Value | 39 | 39 | 0 | 73 | 75.81 | 49.2 - 96.79 | 0.01 - 424.27 | 59.76 | 24.03 - 94.33 | 28 | 28 | 0 | 85.58 | 47.59 | 67.95 - 103.2 | 1.89 - 193.24 | 83.08 | 45.45 - 117.11 | 0.4082 | 0.6762 |
4ТREG_TH1 | Abs_Value | 39 | 39 | 0 | 0.2 | 0.24 | 0.12 - 0.28 | 0 - 0.92 | 0.14 | 0.03 - 0.2 | 28 | 28 | 0 | 0.22 | 0.24 | 0.13 - 0.31 | 0 - 1 | 0.15 | 0.07 - 0.3 | 0.7316 | 0.8954 |
4ТREG_TH17 | Abs_Value | 39 | 39 | 0 | 2.82 | 2.61 | 2 - 3.64 | 0.01 - 11.98 | 1.98 | 0.91 - 4.27 | 28 | 28 | 0 | 3.49 | 3.54 | 2.17 - 4.8 | 0.06 - 15.96 | 2.59 | 1.19 - 4.07 | 0.4005 | 0.6762 |
4ТREG_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.07 | 0.1 | 0.04 - 0.1 | 0 - 0.44 | 0.04 | 0.01 - 0.08 | 28 | 28 | 0 | 0.1 | 0.14 | 0.05 - 0.15 | 0 - 0.47 | 0.04 | 0.02 - 0.1 | 0.3475 | 0.6701 |
4ТREG_TH2 | Abs_Value | 39 | 39 | 0 | 1.54 | 1.37 | 1.11 - 1.97 | 0 - 5.88 | 1.46 | 0.53 - 2.34 | 28 | 28 | 0 | 2.23 | 2.84 | 1.18 - 3.28 | 0.22 - 14.5 | 1.3 | 0.74 - 3.06 | 0.2427 | 0.6696 |
4ТREG_TH22 | Abs_Value | 39 | 39 | 0 | 1.69 | 2.05 | 1.05 - 2.33 | 0.01 - 11.04 | 1.01 | 0.55 - 2.04 | 28 | 28 | 0 | 1.82 | 1.85 | 1.14 - 2.51 | 0 - 8.31 | 1.47 | 0.4 - 2.49 | 0.7863 | 0.9228 |
4ТЕ | Abs_Value | 39 | 39 | 0 | 11.59 | 46.78 | -3.09 - 26.27 | 0.01 - 293.46 | 0.64 | 0.2 - 5.63 | 28 | 28 | 0 | 2.37 | 3.82 | 0.96 - 3.78 | 0.03 - 14.73 | 0.88 | 0.24 - 2.04 | 0.2278 | 0.6696 |
4ТЕ(СТАР2) | Abs_Value | 39 | 39 | 0 | 27.59 | 51.5 | 11.43 - 43.76 | 0.03 - 310.52 | 13.13 | 6.43 - 23.4 | 28 | 28 | 0 | 17.96 | 16.22 | 11.95 - 23.97 | 1.53 - 73.6 | 12.4 | 8.11 - 26.72 | 0.279 | 0.6696 |
4ТЕ_TH1 | Abs_Value | 39 | 39 | 0 | 5.91 | 29.66 | -3.4 - 15.22 | 0 - 185.79 | 0.13 | 0.02 - 1.02 | 28 | 28 | 0 | 0.47 | 1.02 | 0.09 - 0.85 | 0 - 4.5 | 0.14 | 0.01 - 0.33 | 0.2599 | 0.6696 |
4ТЕ_TH17 | Abs_Value | 39 | 39 | 0 | 0.01 | 0.03 | 0 - 0.02 | 0 - 0.17 | 0 | 0 - 0 | 28 | 28 | 0 | 0.01 | 0.02 | 0 - 0.01 | 0 - 0.07 | 0 | 0 - 0 | 0.4728 | 0.6986 |
4ТЕ_Th17TO1 | Abs_Value | 39 | 39 | 0 | 0.13 | 0.65 | -0.08 - 0.33 | 0 - 4.08 | 0.01 | 0 - 0.03 | 28 | 28 | 0 | 0.01 | 0.02 | 0 - 0.02 | 0 - 0.07 | 0 | 0 - 0.01 | 0.2706 | 0.6696 |
4ТЕ_TH2 | Abs_Value | 39 | 39 | 0 | 0.42 | 1.36 | -0.01 - 0.84 | 0 - 6.25 | 0.01 | 0 - 0.12 | 28 | 28 | 0 | 0.08 | 0.13 | 0.04 - 0.13 | 0 - 0.51 | 0.02 | 0 - 0.12 | 0.1315 | 0.6696 |
4ТЕ_TH22 | Abs_Value | 39 | 39 | 0 | 0.01 | 0.01 | 0 - 0.01 | 0 - 0.06 | 0 | 0 - 0.01 | 28 | 28 | 0 | 0 | 0.01 | 0 - 0.01 | 0 - 0.05 | 0 | 0 - 0 | 0.4354 | 0.6834 |
4ТЕ+226+ | Abs_Value | 39 | 39 | 0 | 26.34 | 51.15 | 10.28 - 42.39 | 0.03 - 307.76 | 11.03 | 6.12 - 22.51 | 28 | 28 | 0 | 16.66 | 15.37 | 10.97 - 22.35 | 1.33 - 71.49 | 11.51 | 7.18 - 22.78 | 0.271 | 0.6696 |
4ТЕ+39+ | Abs_Value | 39 | 39 | 0 | 4.33 | 3.99 | 3.08 - 5.59 | 0 - 17.63 | 3.24 | 0.79 - 6.09 | 28 | 28 | 0 | 5.45 | 6.64 | 2.99 - 7.91 | 0.05 - 29.5 | 3.18 | 1.51 - 6.83 | 0.4309 | 0.6834 |
4ТЕ+DR+ | Abs_Value | 39 | 39 | 0 | 20.75 | 45.95 | 6.33 - 35.17 | 0 - 273.14 | 8.21 | 4.06 - 17.59 | 28 | 28 | 0 | 11.62 | 15.22 | 5.98 - 17.26 | 0.27 - 71.42 | 7.25 | 3.38 - 11.19 | 0.2534 | 0.6696 |
4ТЕ+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 7.42 | 9.57 | 4.42 - 10.42 | 0 - 48.37 | 3.79 | 2.16 - 8.9 | 28 | 28 | 0 | 5.1 | 4.7 | 3.36 - 6.84 | 0.27 - 20.57 | 4.19 | 2.35 - 5.99 | 0.1945 | 0.6696 |
4ТЕ+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 2.5 | 10.09 | -0.67 - 5.67 | 0 - 63.72 | 0.68 | 0.29 - 1.27 | 28 | 28 | 0 | 1.05 | 0.99 | 0.68 - 1.42 | 0.02 - 4.29 | 0.78 | 0.36 - 1.29 | 0.3773 | 0.6762 |
4ТЕ+PD-1+ | Abs_Value | 39 | 39 | 0 | 17.67 | 35.09 | 6.66 - 28.68 | 0.02 - 198.43 | 7.84 | 3.82 - 16 | 28 | 28 | 0 | 11.81 | 14.43 | 6.47 - 17.16 | 0.53 - 65.87 | 7.14 | 3.15 - 12.28 | 0.3527 | 0.6701 |
4ТЕ+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 9.85 | 14.26 | 5.38 - 14.33 | 0.02 - 68.31 | 3.85 | 2.12 - 11.01 | 28 | 28 | 0 | 7.28 | 9.7 | 3.69 - 10.88 | 0.31 - 45.47 | 3.94 | 1.99 - 7.31 | 0.3832 | 0.6762 |
4ТЕ+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 7.82 | 22.22 | 0.84 - 14.79 | 0 - 130.12 | 2.71 | 1.56 - 4.95 | 28 | 28 | 0 | 4.53 | 5.52 | 2.49 - 6.58 | 0.23 - 21.97 | 2.11 | 1.41 - 5.09 | 0.3806 | 0.6762 |
4ТЕ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 10.32 | 31.7 | 0.37 - 20.27 | 0 - 193.84 | 3.7 | 2.22 - 6.07 | 28 | 28 | 0 | 5.58 | 6.07 | 3.33 - 7.83 | 0.34 - 22.91 | 3.11 | 2.07 - 5.82 | 0.3679 | 0.6762 |
4ТМ | Abs_Value | 39 | 39 | 0 | 68.73 | 44.83 | 54.66 - 82.8 | 0.29 - 206.37 | 59.16 | 36.36 - 89.43 | 28 | 28 | 0 | 60.2 | 43.52 | 44.08 - 76.32 | 2.7 - 156.95 | 59.02 | 21.18 - 93.81 | 0.4377 | 0.6834 |
8+ | Abs_Value | 39 | 39 | 0 | 338.23 | 532.81 | 171.01 - 505.45 | 3.6 - 2131.88 | 94.25 | 33.79 - 338.12 | 28 | 28 | 0 | 163.88 | 420.4 | 8.16 - 319.59 | 0.65 - 2174.4 | 32.02 | 7.98 - 107.38 | 0.1397 | 0.6696 |
8+ (IM STAT) | Abs_Value | 39 | 39 | 0 | 367.88 | 552.6 | 194.44 - 541.31 | 3.93 - 2176.1 | 99.73 | 39.92 - 499.23 | 28 | 28 | 0 | 190.71 | 457.37 | 21.29 - 360.12 | 0.71 - 2351.17 | 40.68 | 13.82 - 116.25 | 0.1569 | 0.6696 |
8+226+ | Abs_Value | 39 | 39 | 0 | 470.53 | 618.71 | 276.35 - 664.71 | 19.73 - 2309.79 | 182.21 | 83.91 - 662.23 | 28 | 28 | 0 | 254.15 | 484.55 | 74.67 - 433.63 | 7.76 - 2484.23 | 93.15 | 40.59 - 227.28 | 0.1136 | 0.6696 |
8+39+ | Abs_Value | 39 | 39 | 0 | 50.88 | 78.12 | 26.36 - 75.39 | 0.09 - 418.95 | 23.41 | 8.89 - 61.49 | 28 | 28 | 0 | 47.44 | 107.14 | 7.75 - 87.13 | 0.2 - 562.33 | 12.38 | 3.76 - 49.88 | 0.8858 | 0.9621 |
8+DR+ | Abs_Value | 39 | 39 | 0 | 367.32 | 527.47 | 201.78 - 532.87 | 4.94 - 2168.46 | 142.83 | 62.61 - 414.98 | 28 | 28 | 0 | 216.12 | 474.09 | 40.51 - 391.73 | 2.26 - 2431.19 | 63.22 | 19.15 - 162.93 | 0.2241 | 0.6696 |
8+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 135.49 | 198.3 | 73.25 - 197.72 | 5.63 - 815.7 | 39.97 | 17.51 - 139.58 | 28 | 28 | 0 | 76.66 | 134.27 | 26.93 - 126.39 | 1.36 - 704.51 | 40.59 | 10.93 - 84.58 | 0.1526 | 0.6696 |
8+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 144.2 | 244.69 | 67.4 - 221 | 1.37 - 1271.22 | 31.04 | 10.46 - 209.95 | 28 | 28 | 0 | 65.97 | 141.78 | 13.46 - 118.49 | 1 - 719.74 | 15.57 | 7.8 - 62.55 | 0.1044 | 0.6696 |
8+PD-1+ | Abs_Value | 39 | 39 | 0 | 217.19 | 328.31 | 114.15 - 320.23 | 7.78 - 1736.81 | 95 | 38.06 - 229.28 | 28 | 28 | 0 | 133.94 | 258.59 | 38.15 - 229.72 | 1.8 - 1201.16 | 35.47 | 16.3 - 80.32 | 0.2504 | 0.6696 |
8+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 71.54 | 104.23 | 38.83 - 104.25 | 1.45 - 448.19 | 26.52 | 4.16 - 106.41 | 28 | 28 | 0 | 41.87 | 87.52 | 9.45 - 74.29 | 0.7 - 428.96 | 12.39 | 3.78 - 32.22 | 0.2113 | 0.6696 |
8+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 145.65 | 238.86 | 70.69 - 220.62 | 5.05 - 1288.62 | 68.95 | 21.04 - 122.68 | 28 | 28 | 0 | 92.07 | 178.77 | 25.85 - 158.28 | 0.99 - 772.2 | 19.64 | 11.2 - 49.28 | 0.2976 | 0.6696 |
8+TIGIT+ | Abs_Value | 39 | 39 | 0 | 289.85 | 431.67 | 154.37 - 425.33 | 6.42 - 1840.75 | 94.56 | 43.22 - 313.01 | 28 | 28 | 0 | 158.04 | 314.31 | 41.62 - 274.46 | 1.99 - 1491.94 | 43.96 | 19.14 - 109.1 | 0.1529 | 0.6696 |
8EMTM | Abs_Value | 39 | 39 | 0 | 77.74 | 115.56 | 41.47 - 114 | 2.95 - 582.56 | 29.11 | 9.7 - 91.47 | 28 | 28 | 0 | 70.04 | 204.35 | -5.65 - 145.73 | 0.4 - 1077.88 | 11.45 | 3.34 - 45.52 | 0.8582 | 0.9574 |
8EMTM+226+ | Abs_Value | 39 | 39 | 0 | 72.96 | 112.94 | 37.51 - 108.41 | 2.29 - 577.84 | 28.32 | 7.48 - 83.22 | 28 | 28 | 0 | 64.24 | 192.62 | -7.11 - 135.59 | 0.36 - 1020.79 | 10.3 | 2.38 - 43.16 | 0.8312 | 0.9533 |
8EMTM+39+ | Abs_Value | 39 | 39 | 0 | 14.47 | 23.42 | 7.12 - 21.82 | 0.04 - 99.93 | 4.62 | 1.73 - 15.46 | 28 | 28 | 0 | 15.07 | 51.88 | -4.14 - 34.29 | 0.03 - 277.35 | 1.72 | 0.75 - 9.77 | 0.9544 | 0.9731 |
8EMTM+DR+ | Abs_Value | 39 | 39 | 0 | 64.68 | 100.49 | 33.15 - 96.22 | 1.79 - 474.38 | 25.43 | 8.16 - 71.87 | 28 | 28 | 0 | 62.31 | 194.49 | -9.73 - 134.35 | 0.28 - 1026.67 | 6.98 | 1.25 - 30.94 | 0.9532 | 0.9731 |
8EMTM+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 16.56 | 28.57 | 7.59 - 25.52 | 0.1 - 131.33 | 4.96 | 1.16 - 19.06 | 28 | 28 | 0 | 14.71 | 44.65 | -1.83 - 31.25 | 0.1 - 237.98 | 2.42 | 0.29 - 9.52 | 0.8481 | 0.9574 |
8EMTM+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 18.89 | 47.24 | 4.06 - 33.71 | 0.12 - 275.2 | 4.85 | 0.88 - 12.82 | 28 | 28 | 0 | 12.87 | 39.42 | -1.74 - 27.47 | 0.04 - 206 | 0.93 | 0.23 - 7.56 | 0.5727 | 0.7633 |
8EMTM+PD-1+ | Abs_Value | 39 | 39 | 0 | 42.29 | 57.22 | 24.33 - 60.25 | 2.21 - 240.61 | 17.22 | 6.99 - 48.08 | 28 | 28 | 0 | 42.46 | 121.77 | -2.64 - 87.57 | 0.27 - 633.9 | 6.11 | 1.59 - 25.15 | 0.9945 | 0.9945 |
8EMTM+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 13 | 16.61 | 7.78 - 18.21 | 0.2 - 74.77 | 5.86 | 1.15 - 19.09 | 28 | 28 | 0 | 13.87 | 44.21 | -2.5 - 30.25 | 0.08 - 235.25 | 2.36 | 0.47 - 7.78 | 0.9209 | 0.9731 |
8EMTM+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 29.3 | 44.1 | 15.46 - 43.14 | 0.71 - 188.94 | 11.73 | 3.71 - 27.49 | 28 | 28 | 0 | 28.59 | 79.29 | -0.78 - 57.96 | 0.12 - 398.65 | 3.64 | 1.15 - 13.56 | 0.9662 | 0.9781 |
8EMTM+TIGIT+ | Abs_Value | 39 | 39 | 0 | 48.18 | 86.13 | 21.15 - 75.22 | 0.83 - 464.14 | 17.79 | 5.39 - 42.69 | 28 | 28 | 0 | 41.46 | 118.34 | -2.38 - 85.29 | 0.16 - 604.65 | 4.85 | 1.71 - 21.19 | 0.799 | 0.9228 |
8NV | Abs_Value | 39 | 39 | 0 | 7.64 | 9.28 | 4.73 - 10.56 | 0.02 - 46.45 | 5.08 | 1.98 - 8.98 | 28 | 28 | 0 | 11.62 | 11.65 | 7.31 - 15.94 | 0.67 - 55.43 | 7.91 | 5.17 - 17.08 | 0.1405 | 0.6696 |
8NV(СТАР2) | Abs_Value | 39 | 39 | 0 | 9.6 | 11.35 | 6.04 - 13.16 | 0.03 - 49.35 | 5.19 | 2.26 - 10.73 | 28 | 28 | 0 | 11.25 | 10.66 | 7.3 - 15.19 | 1.05 - 48.26 | 6.76 | 4.77 - 14.25 | 0.5468 | 0.7484 |
8NV+226+ | Abs_Value | 39 | 39 | 0 | 8.68 | 10.74 | 5.31 - 12.05 | 0.03 - 49.26 | 4.68 | 1.99 - 10.06 | 28 | 28 | 0 | 9.91 | 9.3 | 6.47 - 13.36 | 0.95 - 40.2 | 5.96 | 4.28 - 12.51 | 0.6174 | 0.7973 |
8NV+39+ | Abs_Value | 39 | 39 | 0 | 0.6 | 0.97 | 0.29 - 0.9 | 0 - 5.17 | 0.3 | 0.06 - 0.64 | 28 | 28 | 0 | 0.67 | 0.81 | 0.36 - 0.97 | 0.01 - 3.73 | 0.44 | 0.13 - 0.8 | 0.7558 | 0.9048 |
8NV+DR+ | Abs_Value | 39 | 39 | 0 | 2.56 | 4.43 | 1.17 - 3.96 | 0.01 - 16.54 | 0.66 | 0.3 - 1.9 | 28 | 28 | 0 | 1.37 | 2.02 | 0.62 - 2.12 | 0.03 - 9.92 | 0.6 | 0.44 - 1.22 | 0.1426 | 0.6696 |
8NV+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 7.04 | 9.42 | 4.09 - 10 | 0 - 43.98 | 3.81 | 1.03 - 8.78 | 28 | 28 | 0 | 9.61 | 10.56 | 5.7 - 13.52 | 0.23 - 47.12 | 5.74 | 3.06 - 12.31 | 0.3088 | 0.6696 |
8NV+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 1.11 | 1.92 | 0.51 - 1.72 | 0 - 9.21 | 0.49 | 0.22 - 0.85 | 28 | 28 | 0 | 0.73 | 0.83 | 0.42 - 1.03 | 0.05 - 3.77 | 0.46 | 0.23 - 0.72 | 0.2655 | 0.6696 |
8NV+PD-1+ | Abs_Value | 39 | 39 | 0 | 1.45 | 2.12 | 0.78 - 2.11 | 0.02 - 10 | 0.52 | 0.2 - 1.5 | 28 | 28 | 0 | 0.91 | 1.11 | 0.5 - 1.32 | 0.05 - 3.96 | 0.44 | 0.23 - 1.06 | 0.1836 | 0.6696 |
8NV+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 0.5 | 0.92 | 0.21 - 0.79 | 0 - 4.91 | 0.15 | 0.03 - 0.5 | 28 | 28 | 0 | 0.31 | 0.36 | 0.18 - 0.45 | 0 - 1.26 | 0.2 | 0.08 - 0.4 | 0.2527 | 0.6696 |
8NV+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 0.95 | 1.35 | 0.52 - 1.37 | 0.01 - 5.16 | 0.39 | 0.15 - 1.12 | 28 | 28 | 0 | 0.6 | 0.89 | 0.27 - 0.92 | 0.04 - 3.31 | 0.25 | 0.17 - 0.38 | 0.2056 | 0.6696 |
8NV+TIGIT+ | Abs_Value | 39 | 39 | 0 | 2.06 | 3.05 | 1.1 - 3.02 | 0.01 - 12.72 | 0.88 | 0.45 - 2.26 | 28 | 28 | 0 | 1.32 | 1.63 | 0.72 - 1.93 | 0.11 - 6.55 | 0.64 | 0.46 - 1.05 | 0.2063 | 0.6696 |
8TREG | Abs_Value | 39 | 39 | 0 | 334.51 | 529.5 | 168.33 - 500.7 | 3.32 - 2109.36 | 93.76 | 33.11 - 326.8 | 28 | 28 | 0 | 166.61 | 430.63 | 7.1 - 326.11 | 0.67 - 2227.15 | 31.77 | 8.02 - 102.77 | 0.158 | 0.6696 |
8ЕМ | Abs_Value | 39 | 39 | 0 | 79.03 | 128.38 | 38.73 - 119.32 | 0.46 - 668.2 | 28.95 | 7.36 - 99.94 | 28 | 28 | 0 | 67.68 | 206.05 | -8.64 - 144 | 0.11 - 1084.06 | 7.04 | 1.01 - 34.8 | 0.7979 | 0.9228 |
8СМ | Abs_Value | 39 | 39 | 0 | 2.88 | 6.14 | 0.95 - 4.81 | 0.01 - 37.25 | 0.94 | 0.56 - 2.43 | 28 | 28 | 0 | 5.32 | 12.63 | 0.64 - 9.99 | 0.08 - 67.57 | 2.36 | 0.34 - 5.01 | 0.351 | 0.6701 |
8СМ(СТАР2) | Abs_Value | 39 | 39 | 0 | 6 | 19.68 | -0.18 - 12.17 | 0.02 - 118.92 | 1.16 | 0.72 - 3.09 | 28 | 28 | 0 | 3.83 | 5.57 | 1.77 - 5.9 | 0.02 - 19.92 | 1.88 | 0.27 - 4.27 | 0.5181 | 0.7325 |
8СМ+226+ | Abs_Value | 39 | 39 | 0 | 5.61 | 19.33 | -0.46 - 11.67 | 0.02 - 118.25 | 1.08 | 0.6 - 2.93 | 28 | 28 | 0 | 3.33 | 4.75 | 1.57 - 5.09 | 0.02 - 16.84 | 1.68 | 0.22 - 3.34 | 0.483 | 0.701 |
8СМ+39+ | Abs_Value | 39 | 39 | 0 | 0.93 | 1.62 | 0.43 - 1.44 | 0 - 9.34 | 0.47 | 0.18 - 0.76 | 28 | 28 | 0 | 1.27 | 1.93 | 0.55 - 1.98 | 0 - 6.95 | 0.2 | 0.07 - 1.77 | 0.4626 | 0.6986 |
8СМ+DR+ | Abs_Value | 39 | 39 | 0 | 5.16 | 17.97 | -0.48 - 10.8 | 0.01 - 107.27 | 0.96 | 0.51 - 2.09 | 28 | 28 | 0 | 2.81 | 5.22 | 0.87 - 4.74 | 0.01 - 19.49 | 0.69 | 0.13 - 1.93 | 0.4428 | 0.6834 |
8СМ+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 1.23 | 2.88 | 0.32 - 2.13 | 0 - 15.65 | 0.25 | 0.11 - 0.88 | 28 | 28 | 0 | 1.12 | 1.58 | 0.54 - 1.71 | 0 - 5.79 | 0.49 | 0.11 - 1.24 | 0.8486 | 0.9574 |
8СМ+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 2.1 | 9.31 | -0.83 - 5.02 | 0 - 58.16 | 0.2 | 0.1 - 0.58 | 28 | 28 | 0 | 0.69 | 1.18 | 0.25 - 1.12 | 0 - 5.17 | 0.2 | 0.05 - 0.61 | 0.3555 | 0.6701 |
8СМ+PD-1+ | Abs_Value | 39 | 39 | 0 | 2.67 | 7.9 | 0.2 - 5.15 | 0.02 - 45.11 | 0.74 | 0.28 - 1.51 | 28 | 28 | 0 | 2.03 | 3.93 | 0.57 - 3.48 | 0.01 - 15.63 | 0.52 | 0.1 - 1.43 | 0.6598 | 0.8324 |
8СМ+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 0.68 | 1.95 | 0.07 - 1.29 | 0 - 9.81 | 0.15 | 0.03 - 0.35 | 28 | 28 | 0 | 0.49 | 1 | 0.12 - 0.86 | 0.01 - 4.45 | 0.11 | 0.04 - 0.38 | 0.6059 | 0.7886 |
8СМ+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 1.99 | 6.19 | 0.05 - 3.94 | 0.01 - 37.26 | 0.62 | 0.21 - 1.18 | 28 | 28 | 0 | 1.53 | 2.99 | 0.43 - 2.64 | 0 - 11.18 | 0.39 | 0.06 - 1.08 | 0.6889 | 0.8621 |
8СМ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 4.09 | 15.41 | -0.75 - 8.93 | 0.01 - 95.42 | 0.8 | 0.34 - 1.64 | 28 | 28 | 0 | 2.22 | 3.86 | 0.79 - 3.65 | 0 - 12.71 | 0.7 | 0.13 - 2.13 | 0.4714 | 0.6986 |
8ТЕ | Abs_Value | 39 | 39 | 0 | 340.55 | 488.28 | 187.3 - 493.79 | 4.38 - 1891.65 | 72.89 | 27.04 - 523.74 | 28 | 28 | 0 | 135.07 | 228.34 | 50.49 - 219.65 | 0.46 - 1033.99 | 42.13 | 12.61 - 131.19 | 0.0251 | 0.6696 |
8ТЕ(СТАР2) | Abs_Value | 39 | 39 | 0 | 399.82 | 532.76 | 232.61 - 567.03 | 7.72 - 2117.62 | 121.61 | 53.59 - 623.55 | 28 | 28 | 0 | 190.71 | 317.08 | 73.26 - 308.16 | 2.04 - 1520.64 | 74.98 | 26.84 - 165.62 | 0.0492 | 0.6696 |
8ТЕ+226+ | Abs_Value | 39 | 39 | 0 | 380.04 | 511.32 | 219.56 - 540.51 | 6.99 - 1998.95 | 102.32 | 50.26 - 599.53 | 28 | 28 | 0 | 176.1 | 299.7 | 65.09 - 287.11 | 1.84 - 1441.91 | 61.81 | 24.47 - 147.36 | 0.0447 | 0.6696 |
8ТЕ+39+ | Abs_Value | 39 | 39 | 0 | 34.3 | 57.18 | 16.35 - 52.25 | 0.05 - 321.3 | 13.22 | 3.65 - 43.95 | 28 | 28 | 0 | 30.36 | 56.92 | 9.27 - 51.44 | 0.07 - 278.04 | 7.6 | 2.95 - 34.51 | 0.781 | 0.9228 |
8ТЕ+DR+ | Abs_Value | 39 | 39 | 0 | 291.49 | 426.01 | 157.79 - 425.2 | 2.61 - 1916.64 | 93.22 | 40.64 - 361.39 | 28 | 28 | 0 | 149.34 | 282.01 | 44.88 - 253.8 | 1.18 - 1379.51 | 39.48 | 15.08 - 122 | 0.1054 | 0.6696 |
8ТЕ+PD-1-TIGIT- | Abs_Value | 39 | 39 | 0 | 109.69 | 170.26 | 56.25 - 163.13 | 2.07 - 692.88 | 26.6 | 9.18 - 117.4 | 28 | 28 | 0 | 50.89 | 89.3 | 17.81 - 83.97 | 0.56 - 459.76 | 20.6 | 5.05 - 62.44 | 0.0716 | 0.6696 |
8ТЕ+PD-1-TIGIT+ | Abs_Value | 39 | 39 | 0 | 121.05 | 193.14 | 60.43 - 181.66 | 0.99 - 921.44 | 24.4 | 8.44 - 190.13 | 28 | 28 | 0 | 51.55 | 101.85 | 13.82 - 89.27 | 0.45 - 504.62 | 14.1 | 4.74 - 55.63 | 0.0612 | 0.6696 |
8ТЕ+PD-1+ | Abs_Value | 39 | 39 | 0 | 169.08 | 280.68 | 80.99 - 257.17 | 3.69 - 1526.37 | 67.37 | 26.03 - 170.51 | 28 | 28 | 0 | 88.27 | 149.38 | 32.94 - 143.6 | 1.03 - 556.25 | 29.97 | 12.58 - 69.83 | 0.1331 | 0.6696 |
8ТЕ+PD-1+TIGIT- | Abs_Value | 39 | 39 | 0 | 56.8 | 90.76 | 28.31 - 85.28 | 0.82 - 403.46 | 18.56 | 2.45 - 72.41 | 28 | 28 | 0 | 27.18 | 48.92 | 9.06 - 45.3 | 0.47 - 190.87 | 7.59 | 2.07 - 25.75 | 0.0906 | 0.6696 |
8ТЕ+PD-1+TIGIT+ | Abs_Value | 39 | 39 | 0 | 112.28 | 201.35 | 49.09 - 175.48 | 2.85 - 1122.91 | 47.52 | 13.89 - 97.11 | 28 | 28 | 0 | 61.09 | 106.19 | 21.76 - 100.43 | 0.56 - 365.38 | 14.54 | 8.69 - 41.59 | 0.1827 | 0.6696 |
8ТЕ+TIGIT+ | Abs_Value | 39 | 39 | 0 | 233.33 | 346.67 | 124.53 - 342.13 | 3.84 - 1498.44 | 77.37 | 26.2 - 269.88 | 28 | 28 | 0 | 112.64 | 198.57 | 39.09 - 186.19 | 1.01 - 870 | 29.7 | 14.87 - 94.69 | 0.0765 | 0.6696 |
8ТМ | Abs_Value | 39 | 39 | 0 | 20.92 | 28 | 12.13 - 29.7 | 0.43 - 149.26 | 12.18 | 4.59 - 22.53 | 28 | 28 | 0 | 20.26 | 37.21 | 6.47 - 34.04 | 0.34 - 179.51 | 5.25 | 1.36 - 17.61 | 0.9375 | 0.9731 |
TREG_CM | Abs_Value | 39 | 39 | 0 | 0.81 | 0.88 | 0.54 - 1.09 | 0 - 4.33 | 0.5 | 0.26 - 1.08 | 28 | 28 | 0 | 1.48 | 2.72 | 0.47 - 2.49 | 0.02 - 14.66 | 0.92 | 0.32 - 1.56 | 0.2223 | 0.6696 |
TREG_EMTM | Abs_Value | 39 | 39 | 0 | 8.82 | 8.27 | 6.22 - 11.41 | 0.05 - 40.11 | 7.21 | 2.95 - 12.43 | 28 | 28 | 0 | 11.9 | 17.5 | 5.42 - 18.38 | 0.05 - 93.26 | 6.51 | 3.01 - 13.22 | 0.3923 | 0.6762 |
TREG_NV | Abs_Value | 39 | 39 | 0 | 0.93 | 0.89 | 0.65 - 1.21 | 0 - 3.03 | 0.71 | 0.21 - 1.47 | 28 | 28 | 0 | 1.21 | 0.82 | 0.91 - 1.52 | 0.01 - 3.4 | 1.13 | 0.63 - 1.75 | 0.1786 | 0.6696 |
TREG_TE | Abs_Value | 39 | 39 | 0 | 2.37 | 1.78 | 1.81 - 2.93 | 0 - 6.11 | 2.06 | 1.15 - 3.5 | 28 | 28 | 0 | 3.04 | 2.65 | 2.06 - 4.02 | 0.19 - 8.97 | 2.17 | 0.97 - 4.09 | 0.2505 | 0.6696 |
TREG+226-TIGIT- | Abs_Value | 39 | 39 | 0 | 0.85 | 0.78 | 0.61 - 1.1 | 0 - 2.66 | 0.63 | 0.17 - 1.39 | 28 | 28 | 0 | 0.88 | 0.74 | 0.61 - 1.15 | 0.04 - 3.18 | 0.69 | 0.34 - 1.18 | 0.8825 | 0.9621 |
TREG+226-TIGIT+ | Abs_Value | 39 | 39 | 0 | 3.39 | 3.18 | 2.39 - 4.39 | 0.01 - 13.35 | 2.67 | 0.95 - 4.88 | 28 | 28 | 0 | 4.62 | 7.57 | 1.82 - 7.43 | 0.22 - 40.78 | 2.82 | 1.46 - 4.13 | 0.4216 | 0.6834 |
TREG+226+ | Abs_Value | 39 | 39 | 0 | 8.82 | 7.4 | 6.49 - 11.14 | 0.04 - 38.28 | 9.02 | 3.48 - 11.72 | 28 | 28 | 0 | 12.15 | 14.13 | 6.92 - 17.38 | 0.85 - 72.45 | 7.91 | 3.79 - 14.59 | 0.2615 | 0.6696 |
TREG+226+TIGIT- | Abs_Value | 39 | 39 | 0 | 1.36 | 1.22 | 0.98 - 1.75 | 0.01 - 4.82 | 0.92 | 0.52 - 1.82 | 28 | 28 | 0 | 1.67 | 1.7 | 1.04 - 2.3 | 0.06 - 7.96 | 1.15 | 0.6 - 1.92 | 0.413 | 0.6773 |
TREG+226+TIGIT+ | Abs_Value | 39 | 39 | 0 | 7.46 | 6.55 | 5.4 - 9.51 | 0.02 - 33.46 | 6.06 | 2.41 - 10.44 | 28 | 28 | 0 | 10.48 | 13.51 | 5.47 - 15.48 | 0.25 - 70.7 | 6.52 | 3.05 - 13.06 | 0.2811 | 0.6696 |
TREG+39+ | Abs_Value | 39 | 39 | 0 | 9.7 | 9.56 | 6.7 - 12.7 | 0.03 - 45.27 | 6.69 | 3.41 - 11.8 | 28 | 28 | 0 | 13.81 | 20.79 | 6.11 - 21.52 | 0.18 - 111.4 | 8.3 | 3.67 - 15.91 | 0.336 | 0.6696 |
TREG+DR+ | Abs_Value | 39 | 39 | 0 | 9.7 | 8.49 | 7.03 - 12.36 | 0.02 - 39.81 | 8.49 | 3.47 - 13.01 | 28 | 28 | 0 | 13.29 | 19.64 | 6.01 - 20.56 | 0.59 - 105.25 | 8.1 | 3.56 - 14.05 | 0.3701 | 0.6762 |
TREG+PD-1+ | Abs_Value | 39 | 39 | 0 | 4.45 | 3.85 | 3.25 - 5.66 | 0.04 - 18.35 | 3.67 | 1.4 - 6.2 | 28 | 28 | 0 | 7.17 | 13.16 | 2.29 - 12.04 | 0.13 - 69.61 | 3.88 | 1.6 - 7.43 | 0.2978 | 0.6696 |
TREG+TIGIT+ | Abs_Value | 39 | 39 | 0 | 10.84 | 9.27 | 7.93 - 13.75 | 0.03 - 42.48 | 10.53 | 3.55 - 14.81 | 28 | 28 | 0 | 15.1 | 20.74 | 7.42 - 22.78 | 0.47 - 111.49 | 9.01 | 5.36 - 17.63 | 0.3169 | 0.6696 |
#Графики без логарифмирования
# 2. Построение графиков
analysis_days <- c("+90") # Фиксируем день +90
cell_populations <- unique(AI_Tcells_filtered$Сell_population)
# Функция для создания одного графика
create_plot <- function(day, cell_pop, data) {
data_subset <- data %>%
filter(Analysis_day == day, Сell_population == cell_pop)
if (nrow(data_subset) > 0) {
p <- ggplot(data_subset, aes(x = cGVHD_present, y = Abs_Value, fill = cGVHD_present)) +
geom_boxplot() +
ggpubr::stat_compare_means(method = "t.test", label.y = 0.8 * max(data_subset$Abs_Value, na.rm = TRUE), label.x = 1.5) +
labs(title = paste("Abs_Value by cGVHD_present\n(Analysis_day =", day, ", Cell Pop =", cell_pop, ")"),
x = "cGVHD_present", y = "Abs_Value") +
theme_bw() +
theme(axis.text.x = element_text(angle = 45, hjust = 1),
plot.title = element_text(hjust = 0.5)) +
scale_y_continuous(limits = function(x) {
range_x <- max(x) - min(x)
c(min(x) - 0.1 * range_x, max(x) + 0.1 * range_x)
})
return(p)
} else {
return(NULL) # Возвращаем NULL, если нет данных
}
}
# Создание всех графиков
plots <- list()
for (cell_pop in cell_populations) {
p <- create_plot("+90", cell_pop, AI_Tcells_filtered)
if (!is.null(p)) {
print(p)
plots[[paste0("plot_90_", cell_pop)]] <- p
#ggsave(paste0("plot_90_", cell_pop, ".png"), plot = p, width = 10, height = 7)
}
}
# 1. Добавление группирующей переменной для facet_wrap)
AI_Tcells_filtered_facet <- AI_Tcells_filtered %>%
mutate(group = paste0("Group ", (as.numeric(Сell_population) -1) %/% 5 +1))
# 2. Построение графиков с использованием facet_wrap
analysis_days <- unique(AI_Tcells_filtered_facet$Analysis_day)
groups <- unique(AI_Tcells_filtered_facet$group)
for (day in analysis_days) {
for (grp in groups) {
data_subset <- AI_Tcells_filtered_facet %>%
filter(Analysis_day == day, group == grp)
if (nrow(data_subset) > 0) {
# Логарифмирование значений Abs_Value
data_subset <- data_subset %>%
mutate(log_Abs_Value = log1p(Abs_Value)) # log1p для обработки нулей
max_val <- max(data_subset$log_Abs_Value, na.rm = TRUE)
p <- ggplot(data_subset, aes(x = cGVHD_present, y = log_Abs_Value, fill = cGVHD_present)) +
geom_boxplot() +
ggpubr::stat_compare_means(method = "t.test", label.y = max_val - 0.1 * max_val) +
labs(title = paste("log(Abs_Value + 1) by cGVHD_present\n(Analysis_day =", day, ", Group =", grp, ")"),
x = "cGVHD_present", y = "log(Abs_Value + 1)") +
theme_bw() +
theme(axis.text.x = element_text(angle = 45, hjust = 1),
plot.title = element_text(hjust = 0.5)) +
facet_wrap(~Сell_population, scales = "free_x")
print(p)
#ggsave(paste0("plot_log_", day, "_group_", grp, ".png"), plot = p, width = 12, height = 8)
}
}
}
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
## Warning: Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Computation failed in `stat_compare_means()`.
## Caused by error:
## ! аргумент "x" пропущен, умолчаний нет
#GLM wide data
##Подготовка данных
data_day90 <- filter(AI_Tcells_filtered, Analysis_day == "+90")
data_day180 <- filter(AI_Tcells_filtered, Analysis_day == "+180")
data_wide_90 <- data_day90 %>%
pivot_wider(names_from = Сell_population, values_from = Abs_Value)
data_90 <- data_wide_90 %>%
select(-ID, -Time_OS, -cGVHD_time, -Analysis_day, -Analysis_time)
data_wide_180 <- data_day180 %>%
pivot_wider(names_from = Сell_population, values_from = Abs_Value)
data_180 <- data_wide_180 %>%
select(-ID, -Time_OS, -cGVHD_time, -Analysis_day, -Analysis_time)
model_90 <- glm(cGVHD_present ~ ., data = data_90, family = binomial)
# Модель для 180-го дня
model_180 <- glm(cGVHD_present ~ ., data = data_180, family = binomial)
summary(model_90)
##
## Call:
## glm(formula = cGVHD_present ~ ., family = binomial, data = data_90)
##
## Coefficients: (98 not defined because of singularities)
## Estimate Std. Error z value Pr(>|z|)
## (Intercept) -2.478e+01 3.493e+05 0 1
## `4_TFH` 2.814e+00 1.169e+05 0 1
## `4_TH1` 1.197e+01 2.993e+05 0 1
## `4_TH17` -2.102e+01 2.303e+05 0 1
## `4_Th17TO1` -4.085e-01 1.115e+05 0 1
## `4_TH2` 6.069e+01 7.583e+05 0 1
## `4_TH22` 3.035e+01 3.068e+05 0 1
## `4+ (IM STAT)` -2.700e+00 3.472e+04 0 1
## `4+` 1.901e+00 2.483e+04 0 1
## `4+226+` -9.562e+01 1.002e+06 0 1
## `4+39+` 8.119e+00 1.808e+05 0 1
## `4+DR+` -6.441e+00 1.808e+05 0 1
## `4+PD-1+` 2.392e+09 4.572e+13 0 1
## `4+PD-1+TIGIT-` -2.392e+09 4.572e+13 0 1
## `4+PD-1+TIGIT+` -2.369e+08 5.477e+13 0 1
## `4+PD-1-TIGIT-` 7.296e+01 8.486e+05 0 1
## `4+PD-1-TIGIT+` 2.155e+09 8.382e+13 0 1
## `4+TIGIT+` -2.155e+09 8.382e+13 0 1
## `4NV(СТАР2)` 3.651e+09 9.226e+13 0 1
## `4NV` -1.696e+01 2.263e+05 0 1
## `4NV_TH1` -4.673e+01 1.095e+06 0 1
## `4NV_TH17` -6.398e+01 1.775e+06 0 1
## `4NV_Th17TO1` 8.650e+01 5.334e+06 0 1
## `4NV_TH2` -3.296e+01 5.916e+05 0 1
## `4NV_TH22` 2.725e+02 2.957e+06 0 1
## `4NV+226+` 1.107e+02 1.253e+06 0 1
## `4NV+39+` 4.507e+01 1.144e+06 0 1
## `4NV+DR+` -1.925e+01 5.060e+05 0 1
## `4NV+PD1+` 1.273e+09 6.849e+14 0 1
## `4NV+PD-1+TIGIT-` -4.924e+09 6.852e+14 0 1
## `4NV+PD-1+TIGIT+` -2.167e+11 3.916e+15 0 1
## `4NV+PD-1-TIGIT-` -3.651e+09 9.226e+13 0 1
## `4NV+PD-1-TIGIT+` -2.154e+11 4.110e+15 0 1
## `4NV+TIGIT+` 2.117e+11 4.058e+15 0 1
## `4ЕМ` -7.693e+00 1.312e+05 0 1
## `4ЕМ_TH1` 9.051e+00 5.941e+05 0 1
## `4ЕМ_TH17` 6.029e+02 7.161e+06 0 1
## `4ЕМ_Th17TO1` 7.375e+01 2.839e+06 0 1
## `4ЕМ_TH2` -4.820e+01 6.447e+05 0 1
## `4ЕМ_TH22` 2.975e+03 4.646e+07 0 1
## `4ЕМ+226+` 1.163e+02 1.340e+06 0 1
## `4ЕМ+39+` -7.999e+00 1.989e+05 0 1
## `4ЕМ+DR+` 8.134e+00 2.964e+05 0 1
## `4ЕМ+PD1+` 1.167e+09 5.108e+13 0 1
## `4ЕМ+PD1+TIGIT-` -8.231e+09 9.278e+13 0 1
## `4ЕМ+PD1+TIGIT+` -5.654e+09 1.127e+14 0 1
## `4ЕМ+PD1-TIGIT-` -7.064e+09 7.265e+13 0 1
## `4ЕМ+PD1-TIGIT+` -4.487e+09 1.366e+14 0 1
## `4ЕМ+TIGIT+` -2.578e+09 1.365e+14 0 1
## `4ЕМTM` 7.064e+09 7.265e+13 0 1
## `4СМ(СТАР2)` -5.354e+09 1.173e+14 0 1
## `4СМ` -1.240e+00 2.015e+05 0 1
## `4СМ_TH1` -2.607e+01 1.087e+06 0 1
## `4СМ_TH17` 3.976e+01 7.140e+05 0 1
## `4СМ_Th17TO1` 9.995e+01 1.573e+06 0 1
## `4СМ_TH2` -7.502e+01 9.984e+05 0 1
## `4СМ_TH22` -3.550e+01 1.285e+06 0 1
## `4СМ+226+` 1.126e+02 1.124e+06 0 1
## `4СМ+39+` -1.046e+01 2.979e+05 0 1
## `4СМ+DR+` 9.785e+00 1.619e+05 0 1
## `4СМ+PD1+` 5.137e+09 1.271e+14 0 1
## `4СМ+PD1+TIGIT-` 2.173e+08 9.713e+13 0 1
## `4СМ+PD1+TIGIT+` -1.778e+10 2.012e+14 0 1
## `4СМ+PD1-TIGIT-` 5.354e+09 1.173e+14 0 1
## `4СМ+PD1-TIGIT+` -1.264e+10 1.672e+14 0 1
## `4СМ+TIGIT+` 1.800e+10 2.468e+14 0 1
## `4ТM_TH1` -1.488e+01 3.306e+05 0 1
## `4ТM_TH17` NA NA NA NA
## `4ТM_Th17TO1` NA NA NA NA
## `4ТM_TH2` NA NA NA NA
## `4ТM_TH22` NA NA NA NA
## `4ТREG(СТАР2)` NA NA NA NA
## `4ТREG` NA NA NA NA
## `4ТREG_TH1` NA NA NA NA
## `4ТREG_TH17` NA NA NA NA
## `4ТREG_Th17TO1` NA NA NA NA
## `4ТREG_TH2` NA NA NA NA
## `4ТREG_TH22` NA NA NA NA
## `4ТЕ(СТАР2)` NA NA NA NA
## `4ТЕ` NA NA NA NA
## `4ТЕ_TH1` NA NA NA NA
## `4ТЕ_TH17` NA NA NA NA
## `4ТЕ_Th17TO1` NA NA NA NA
## `4ТЕ_TH2` NA NA NA NA
## `4ТЕ_TH22` NA NA NA NA
## `4ТЕ+226+` NA NA NA NA
## `4ТЕ+39+` NA NA NA NA
## `4ТЕ+DR+` NA NA NA NA
## `4ТЕ+PD-1+` NA NA NA NA
## `4ТЕ+PD-1+TIGIT-` NA NA NA NA
## `4ТЕ+PD-1+TIGIT+` NA NA NA NA
## `4ТЕ+PD-1-TIGIT-` NA NA NA NA
## `4ТЕ+PD-1-TIGIT+` NA NA NA NA
## `4ТЕ+TIGIT+` NA NA NA NA
## `4ТМ` NA NA NA NA
## `8+ (IM STAT)` NA NA NA NA
## `8+` NA NA NA NA
## `8+226+` NA NA NA NA
## `8+39+` NA NA NA NA
## `8+DR+` NA NA NA NA
## `8+PD-1+` NA NA NA NA
## `8+PD-1+TIGIT-` NA NA NA NA
## `8+PD-1+TIGIT+` NA NA NA NA
## `8+PD-1-TIGIT-` NA NA NA NA
## `8+PD-1-TIGIT+` NA NA NA NA
## `8+TIGIT+` NA NA NA NA
## `8EMTM` NA NA NA NA
## `8EMTM+226+` NA NA NA NA
## `8EMTM+39+` NA NA NA NA
## `8EMTM+DR+` NA NA NA NA
## `8EMTM+PD-1+` NA NA NA NA
## `8EMTM+PD-1+TIGIT-` NA NA NA NA
## `8EMTM+PD-1+TIGIT+` NA NA NA NA
## `8EMTM+PD-1-TIGIT-` NA NA NA NA
## `8EMTM+PD-1-TIGIT+` NA NA NA NA
## `8EMTM+TIGIT+` NA NA NA NA
## `8NV(СТАР2)` NA NA NA NA
## `8NV` NA NA NA NA
## `8NV+226+` NA NA NA NA
## `8NV+39+` NA NA NA NA
## `8NV+DR+` NA NA NA NA
## `8NV+PD-1+` NA NA NA NA
## `8NV+PD-1+TIGIT-` NA NA NA NA
## `8NV+PD-1+TIGIT+` NA NA NA NA
## `8NV+PD-1-TIGIT-` NA NA NA NA
## `8NV+PD-1-TIGIT+` NA NA NA NA
## `8NV+TIGIT+` NA NA NA NA
## `8TREG` NA NA NA NA
## `8ЕМ` NA NA NA NA
## `8СМ(СТАР2)` NA NA NA NA
## `8СМ` NA NA NA NA
## `8СМ+226+` NA NA NA NA
## `8СМ+39+` NA NA NA NA
## `8СМ+DR+` NA NA NA NA
## `8СМ+PD-1+` NA NA NA NA
## `8СМ+PD-1+TIGIT-` NA NA NA NA
## `8СМ+PD-1+TIGIT+` NA NA NA NA
## `8СМ+PD-1-TIGIT-` NA NA NA NA
## `8СМ+PD-1-TIGIT+` NA NA NA NA
## `8СМ+TIGIT+` NA NA NA NA
## `8ТЕ(СТАР2)` NA NA NA NA
## `8ТЕ` NA NA NA NA
## `8ТЕ+226+` NA NA NA NA
## `8ТЕ+39+` NA NA NA NA
## `8ТЕ+DR+` NA NA NA NA
## `8ТЕ+PD-1+` NA NA NA NA
## `8ТЕ+PD-1+TIGIT-` NA NA NA NA
## `8ТЕ+PD-1+TIGIT+` NA NA NA NA
## `8ТЕ+PD-1-TIGIT-` NA NA NA NA
## `8ТЕ+PD-1-TIGIT+` NA NA NA NA
## `8ТЕ+TIGIT+` NA NA NA NA
## `8ТМ` NA NA NA NA
## TREG_CM NA NA NA NA
## TREG_EMTM NA NA NA NA
## TREG_NV NA NA NA NA
## TREG_TE NA NA NA NA
## `TREG+226+` NA NA NA NA
## `TREG+226+TIGIT-` NA NA NA NA
## `TREG+226+TIGIT+` NA NA NA NA
## `TREG+226-TIGIT-` NA NA NA NA
## `TREG+226-TIGIT+` NA NA NA NA
## `TREG+39+` NA NA NA NA
## `TREG+DR+` NA NA NA NA
## `TREG+PD-1+` NA NA NA NA
## `TREG+TIGIT+` NA NA NA NA
##
## (Dispersion parameter for binomial family taken to be 1)
##
## Null deviance: 9.1068e+01 on 66 degrees of freedom
## Residual deviance: 3.8871e-10 on 0 degrees of freedom
## AIC: 134
##
## Number of Fisher Scoring iterations: 25
summary(model_180)
##
## Call:
## glm(formula = cGVHD_present ~ ., family = binomial, data = data_180)
##
## Coefficients: (123 not defined because of singularities)
## Estimate Std. Error z value Pr(>|z|)
## (Intercept) -2.139e+01 8.538e+05 0 1
## `4_TFH` 9.432e-02 4.383e+04 0 1
## `4_TH1` 1.968e+00 5.945e+04 0 1
## `4_TH17` -1.234e+00 1.196e+05 0 1
## `4_Th17TO1` -2.081e+00 1.644e+05 0 1
## `4_TH2` -3.419e+00 7.776e+04 0 1
## `4_TH22` 7.887e+00 2.891e+05 0 1
## `4+ (IM STAT)` -4.519e-01 3.940e+04 0 1
## `4+` 1.518e+00 3.746e+04 0 1
## `4+226+` -3.920e+00 1.053e+05 0 1
## `4+39+` -2.813e-01 1.057e+05 0 1
## `4+DR+` 4.347e-02 3.146e+04 0 1
## `4+PD-1+` -9.565e+08 2.509e+13 0 1
## `4+PD-1+TIGIT-` 9.565e+08 2.509e+13 0 1
## `4+PD-1+TIGIT+` 1.508e+08 3.255e+13 0 1
## `4+PD-1-TIGIT-` 3.759e+00 1.165e+05 0 1
## `4+PD-1-TIGIT+` -8.057e+08 1.597e+13 0 1
## `4+TIGIT+` 8.057e+08 1.597e+13 0 1
## `4NV(СТАР2)` 2.940e+09 4.100e+13 0 1
## `4NV` -3.941e+00 1.597e+05 0 1
## `4NV_TH1` 1.105e+00 3.562e+05 0 1
## `4NV_TH17` -5.061e+00 1.356e+06 0 1
## `4NV_Th17TO1` -4.550e+01 6.278e+06 0 1
## `4NV_TH2` 2.648e+00 1.768e+05 0 1
## `4NV_TH22` -1.653e+01 5.084e+06 0 1
## `4NV+226+` 5.451e+00 2.154e+05 0 1
## `4NV+39+` 3.068e+01 1.403e+06 0 1
## `4NV+DR+` 8.034e+00 1.962e+05 0 1
## `4NV+PD1+` -4.005e+10 1.110e+15 0 1
## `4NV+PD-1+TIGIT-` 3.711e+10 1.086e+15 0 1
## `4NV+PD-1+TIGIT+` -1.309e+10 1.119e+15 0 1
## `4NV+PD-1-TIGIT-` -2.940e+09 4.100e+13 0 1
## `4NV+PD-1-TIGIT+` -5.314e+10 1.279e+15 0 1
## `4NV+TIGIT+` 5.021e+10 1.249e+15 0 1
## `4ЕМ` -1.272e+00 1.459e+05 0 1
## `4ЕМ_TH1` -2.770e+00 2.901e+05 0 1
## `4ЕМ_TH17` 2.145e+02 1.343e+07 0 1
## `4ЕМ_Th17TO1` 1.317e+01 8.963e+05 0 1
## `4ЕМ_TH2` 2.101e+01 1.147e+06 0 1
## `4ЕМ_TH22` -3.374e+03 6.507e+07 0 1
## `4ЕМ+226+` 1.086e+00 5.482e+04 0 1
## `4ЕМ+39+` -6.593e-01 1.766e+05 0 1
## `4ЕМ+DR+` NA NA NA NA
## `4ЕМ+PD1+` NA NA NA NA
## `4ЕМ+PD1+TIGIT-` NA NA NA NA
## `4ЕМ+PD1+TIGIT+` NA NA NA NA
## `4ЕМ+PD1-TIGIT-` NA NA NA NA
## `4ЕМ+PD1-TIGIT+` NA NA NA NA
## `4ЕМ+TIGIT+` NA NA NA NA
## `4ЕМTM` NA NA NA NA
## `4СМ(СТАР2)` NA NA NA NA
## `4СМ` NA NA NA NA
## `4СМ_TH1` NA NA NA NA
## `4СМ_TH17` NA NA NA NA
## `4СМ_Th17TO1` NA NA NA NA
## `4СМ_TH2` NA NA NA NA
## `4СМ_TH22` NA NA NA NA
## `4СМ+226+` NA NA NA NA
## `4СМ+39+` NA NA NA NA
## `4СМ+DR+` NA NA NA NA
## `4СМ+PD1+` NA NA NA NA
## `4СМ+PD1+TIGIT-` NA NA NA NA
## `4СМ+PD1+TIGIT+` NA NA NA NA
## `4СМ+PD1-TIGIT-` NA NA NA NA
## `4СМ+PD1-TIGIT+` NA NA NA NA
## `4СМ+TIGIT+` NA NA NA NA
## `4ТM_TH1` NA NA NA NA
## `4ТM_TH17` NA NA NA NA
## `4ТM_Th17TO1` NA NA NA NA
## `4ТM_TH2` NA NA NA NA
## `4ТM_TH22` NA NA NA NA
## `4ТREG(СТАР2)` NA NA NA NA
## `4ТREG` NA NA NA NA
## `4ТREG_TH1` NA NA NA NA
## `4ТREG_TH17` NA NA NA NA
## `4ТREG_Th17TO1` NA NA NA NA
## `4ТREG_TH2` NA NA NA NA
## `4ТREG_TH22` NA NA NA NA
## `4ТЕ(СТАР2)` NA NA NA NA
## `4ТЕ` NA NA NA NA
## `4ТЕ_TH1` NA NA NA NA
## `4ТЕ_TH17` NA NA NA NA
## `4ТЕ_Th17TO1` NA NA NA NA
## `4ТЕ_TH2` NA NA NA NA
## `4ТЕ_TH22` NA NA NA NA
## `4ТЕ+226+` NA NA NA NA
## `4ТЕ+39+` NA NA NA NA
## `4ТЕ+DR+` NA NA NA NA
## `4ТЕ+PD-1+` NA NA NA NA
## `4ТЕ+PD-1+TIGIT-` NA NA NA NA
## `4ТЕ+PD-1+TIGIT+` NA NA NA NA
## `4ТЕ+PD-1-TIGIT-` NA NA NA NA
## `4ТЕ+PD-1-TIGIT+` NA NA NA NA
## `4ТЕ+TIGIT+` NA NA NA NA
## `4ТМ` NA NA NA NA
## `8+ (IM STAT)` NA NA NA NA
## `8+` NA NA NA NA
## `8+226+` NA NA NA NA
## `8+39+` NA NA NA NA
## `8+DR+` NA NA NA NA
## `8+PD-1+` NA NA NA NA
## `8+PD-1+TIGIT-` NA NA NA NA
## `8+PD-1+TIGIT+` NA NA NA NA
## `8+PD-1-TIGIT-` NA NA NA NA
## `8+PD-1-TIGIT+` NA NA NA NA
## `8+TIGIT+` NA NA NA NA
## `8EMTM` NA NA NA NA
## `8EMTM+226+` NA NA NA NA
## `8EMTM+39+` NA NA NA NA
## `8EMTM+DR+` NA NA NA NA
## `8EMTM+PD-1+` NA NA NA NA
## `8EMTM+PD-1+TIGIT-` NA NA NA NA
## `8EMTM+PD-1+TIGIT+` NA NA NA NA
## `8EMTM+PD-1-TIGIT-` NA NA NA NA
## `8EMTM+PD-1-TIGIT+` NA NA NA NA
## `8EMTM+TIGIT+` NA NA NA NA
## `8NV(СТАР2)` NA NA NA NA
## `8NV` NA NA NA NA
## `8NV+226+` NA NA NA NA
## `8NV+39+` NA NA NA NA
## `8NV+DR+` NA NA NA NA
## `8NV+PD-1+` NA NA NA NA
## `8NV+PD-1+TIGIT-` NA NA NA NA
## `8NV+PD-1+TIGIT+` NA NA NA NA
## `8NV+PD-1-TIGIT-` NA NA NA NA
## `8NV+PD-1-TIGIT+` NA NA NA NA
## `8NV+TIGIT+` NA NA NA NA
## `8TREG` NA NA NA NA
## `8ЕМ` NA NA NA NA
## `8СМ(СТАР2)` NA NA NA NA
## `8СМ` NA NA NA NA
## `8СМ+226+` NA NA NA NA
## `8СМ+39+` NA NA NA NA
## `8СМ+DR+` NA NA NA NA
## `8СМ+PD-1+` NA NA NA NA
## `8СМ+PD-1+TIGIT-` NA NA NA NA
## `8СМ+PD-1+TIGIT+` NA NA NA NA
## `8СМ+PD-1-TIGIT-` NA NA NA NA
## `8СМ+PD-1-TIGIT+` NA NA NA NA
## `8СМ+TIGIT+` NA NA NA NA
## `8ТЕ(СТАР2)` NA NA NA NA
## `8ТЕ` NA NA NA NA
## `8ТЕ+226+` NA NA NA NA
## `8ТЕ+39+` NA NA NA NA
## `8ТЕ+DR+` NA NA NA NA
## `8ТЕ+PD-1+` NA NA NA NA
## `8ТЕ+PD-1+TIGIT-` NA NA NA NA
## `8ТЕ+PD-1+TIGIT+` NA NA NA NA
## `8ТЕ+PD-1-TIGIT-` NA NA NA NA
## `8ТЕ+PD-1-TIGIT+` NA NA NA NA
## `8ТЕ+TIGIT+` NA NA NA NA
## `8ТМ` NA NA NA NA
## TREG_CM NA NA NA NA
## TREG_EMTM NA NA NA NA
## TREG_NV NA NA NA NA
## TREG_TE NA NA NA NA
## `TREG+226+` NA NA NA NA
## `TREG+226+TIGIT-` NA NA NA NA
## `TREG+226+TIGIT+` NA NA NA NA
## `TREG+226-TIGIT-` NA NA NA NA
## `TREG+226-TIGIT+` NA NA NA NA
## `TREG+39+` NA NA NA NA
## `TREG+DR+` NA NA NA NA
## `TREG+PD-1+` NA NA NA NA
## `TREG+TIGIT+` NA NA NA NA
##
## (Dispersion parameter for binomial family taken to be 1)
##
## Null deviance: 5.3467e+01 on 41 degrees of freedom
## Residual deviance: 2.4369e-10 on 0 degrees of freedom
## AIC: 84
##
## Number of Fisher Scoring iterations: 25
#{r} car::vif(model_90) car::vif(model_180)
#Корреляции
data_90_num <- data_90 %>%
select(-cGVHD_present)
data_90_cor <- cor(data_90_num)
corrplot(data_90_cor, method = "circle", type = "upper", tl.col = "black", tl.cex = 0.7)
corrplot(data_90_cor, method = 'number')
correlation_matrix <- cor(model.matrix(model_90))
## Warning in cor(model.matrix(model_90)): стандартное отклонение нулевое
# Визуализация тепловой карты
melted_cor <- reshape2::melt(correlation_matrix)
ggplot(data = melted_cor, aes(x = Var1, y = Var2, fill = value)) +
geom_tile() +
scale_fill_gradient2(low = "blue", mid = "white", high = "red") +
theme(axis.text.x = element_text(angle = 90, hjust = 1)) +
labs(title = "Матрица корреляций", fill = "Коэффициент корреляции")
#LASSO применяет L1-регуляризацию, которая добавляет штрафной член к функции потерь. Этот штраф уменьшает коэффициенты некоторых предикторов до нуля, эффективно исключая их из модели.
##90
# Подготовка данных: X - матрица предикторов, y - вектор отклика
X <- model.matrix(cGVHD_present ~ ., data = data_90)
y <- data_90$cGVHD_present
# Построение модели LASSO
lasso_model <- glmnet(X, y, family = "binomial", alpha = 1) # alpha = 1 для LASSO
# Выбор наилучшего lambda с помощью кросс-валидации
cv_lasso <- cv.glmnet(X, y, family = "binomial", alpha = 1)
best_lambda <- cv_lasso$lambda.min
# Модель с наилучшим lambda
lasso_model_best <- glmnet(X, y, family = "binomial", alpha = 1, lambda = best_lambda)
# Коэффициенты
coef(lasso_model_best)
## 166 x 1 sparse Matrix of class "dgCMatrix"
## s0
## (Intercept) -0.352883859
## (Intercept) .
## `4_TFH` .
## `4_TH1` .
## `4_TH17` .
## `4_Th17TO1` .
## `4_TH2` .
## `4_TH22` .
## `4+ (IM STAT)` .
## `4+` .
## `4+226+` .
## `4+39+` .
## `4+DR+` .
## `4+PD-1+` .
## `4+PD-1+TIGIT-` .
## `4+PD-1+TIGIT+` .
## `4+PD-1-TIGIT-` .
## `4+PD-1-TIGIT+` .
## `4+TIGIT+` .
## `4NV(СТАР2)` .
## `4NV` .
## `4NV_TH1` .
## `4NV_TH17` .
## `4NV_Th17TO1` .
## `4NV_TH2` 0.007483848
## `4NV_TH22` .
## `4NV+226+` .
## `4NV+39+` .
## `4NV+DR+` .
## `4NV+PD1+` .
## `4NV+PD-1+TIGIT-` .
## `4NV+PD-1+TIGIT+` .
## `4NV+PD-1-TIGIT-` .
## `4NV+PD-1-TIGIT+` .
## `4NV+TIGIT+` .
## `4ЕМ` .
## `4ЕМ_TH1` .
## `4ЕМ_TH17` .
## `4ЕМ_Th17TO1` .
## `4ЕМ_TH2` .
## `4ЕМ_TH22` .
## `4ЕМ+226+` .
## `4ЕМ+39+` .
## `4ЕМ+DR+` .
## `4ЕМ+PD1+` .
## `4ЕМ+PD1+TIGIT-` .
## `4ЕМ+PD1+TIGIT+` .
## `4ЕМ+PD1-TIGIT-` .
## `4ЕМ+PD1-TIGIT+` .
## `4ЕМ+TIGIT+` .
## `4ЕМTM` .
## `4СМ(СТАР2)` .
## `4СМ` .
## `4СМ_TH1` .
## `4СМ_TH17` .
## `4СМ_Th17TO1` .
## `4СМ_TH2` .
## `4СМ_TH22` .
## `4СМ+226+` .
## `4СМ+39+` .
## `4СМ+DR+` .
## `4СМ+PD1+` .
## `4СМ+PD1+TIGIT-` .
## `4СМ+PD1+TIGIT+` .
## `4СМ+PD1-TIGIT-` .
## `4СМ+PD1-TIGIT+` .
## `4СМ+TIGIT+` .
## `4ТM_TH1` .
## `4ТM_TH17` .
## `4ТM_Th17TO1` .
## `4ТM_TH2` .
## `4ТM_TH22` .
## `4ТREG(СТАР2)` .
## `4ТREG` .
## `4ТREG_TH1` .
## `4ТREG_TH17` .
## `4ТREG_Th17TO1` .
## `4ТREG_TH2` .
## `4ТREG_TH22` .
## `4ТЕ(СТАР2)` .
## `4ТЕ` .
## `4ТЕ_TH1` .
## `4ТЕ_TH17` .
## `4ТЕ_Th17TO1` .
## `4ТЕ_TH2` .
## `4ТЕ_TH22` .
## `4ТЕ+226+` .
## `4ТЕ+39+` .
## `4ТЕ+DR+` .
## `4ТЕ+PD-1+` .
## `4ТЕ+PD-1+TIGIT-` .
## `4ТЕ+PD-1+TIGIT+` .
## `4ТЕ+PD-1-TIGIT-` .
## `4ТЕ+PD-1-TIGIT+` .
## `4ТЕ+TIGIT+` .
## `4ТМ` .
## `8+ (IM STAT)` .
## `8+` .
## `8+226+` .
## `8+39+` .
## `8+DR+` .
## `8+PD-1+` .
## `8+PD-1+TIGIT-` .
## `8+PD-1+TIGIT+` .
## `8+PD-1-TIGIT-` .
## `8+PD-1-TIGIT+` .
## `8+TIGIT+` .
## `8EMTM` .
## `8EMTM+226+` .
## `8EMTM+39+` .
## `8EMTM+DR+` .
## `8EMTM+PD-1+` .
## `8EMTM+PD-1+TIGIT-` .
## `8EMTM+PD-1+TIGIT+` .
## `8EMTM+PD-1-TIGIT-` .
## `8EMTM+PD-1-TIGIT+` .
## `8EMTM+TIGIT+` .
## `8NV(СТАР2)` .
## `8NV` .
## `8NV+226+` .
## `8NV+39+` .
## `8NV+DR+` .
## `8NV+PD-1+` .
## `8NV+PD-1+TIGIT-` .
## `8NV+PD-1+TIGIT+` .
## `8NV+PD-1-TIGIT-` .
## `8NV+PD-1-TIGIT+` .
## `8NV+TIGIT+` .
## `8TREG` .
## `8ЕМ` .
## `8СМ(СТАР2)` .
## `8СМ` .
## `8СМ+226+` .
## `8СМ+39+` .
## `8СМ+DR+` .
## `8СМ+PD-1+` .
## `8СМ+PD-1+TIGIT-` .
## `8СМ+PD-1+TIGIT+` .
## `8СМ+PD-1-TIGIT-` .
## `8СМ+PD-1-TIGIT+` .
## `8СМ+TIGIT+` .
## `8ТЕ(СТАР2)` .
## `8ТЕ` .
## `8ТЕ+226+` .
## `8ТЕ+39+` .
## `8ТЕ+DR+` .
## `8ТЕ+PD-1+` .
## `8ТЕ+PD-1+TIGIT-` .
## `8ТЕ+PD-1+TIGIT+` .
## `8ТЕ+PD-1-TIGIT-` .
## `8ТЕ+PD-1-TIGIT+` .
## `8ТЕ+TIGIT+` .
## `8ТМ` .
## TREG_CM .
## TREG_EMTM .
## TREG_NV .
## TREG_TE .
## `TREG+226+` .
## `TREG+226+TIGIT-` .
## `TREG+226+TIGIT+` .
## `TREG+226-TIGIT-` .
## `TREG+226-TIGIT+` .
## `TREG+39+` .
## `TREG+DR+` .
## `TREG+PD-1+` .
## `TREG+TIGIT+` .
##180
# Подготовка данных: X - матрица предикторов, y - вектор отклика
X <- model.matrix(cGVHD_present ~ ., data = data_180)
y <- data_180$cGVHD_present
# Построение модели LASSO
lasso_model <- glmnet(X, y, family = "binomial", alpha = 1) # alpha = 1 для LASSO
# Выбор наилучшего lambda с помощью кросс-валидации
cv_lasso <- cv.glmnet(X, y, family = "binomial", alpha = 1)
best_lambda <- cv_lasso$lambda.min
# Модель с наилучшим lambda
lasso_model_best <- glmnet(X, y, family = "binomial", alpha = 1, lambda = best_lambda)
# Коэффициенты
coef(lasso_model_best)
## 166 x 1 sparse Matrix of class "dgCMatrix"
## s0
## (Intercept) -6.931472e-01
## (Intercept) .
## `4_TFH` .
## `4_TH1` .
## `4_TH17` .
## `4_Th17TO1` .
## `4_TH2` .
## `4_TH22` .
## `4+ (IM STAT)` .
## `4+` .
## `4+226+` .
## `4+39+` .
## `4+DR+` .
## `4+PD-1+` .
## `4+PD-1+TIGIT-` .
## `4+PD-1+TIGIT+` .
## `4+PD-1-TIGIT-` .
## `4+PD-1-TIGIT+` .
## `4+TIGIT+` .
## `4NV(СТАР2)` .
## `4NV` .
## `4NV_TH1` .
## `4NV_TH17` .
## `4NV_Th17TO1` 8.628088e-16
## `4NV_TH2` .
## `4NV_TH22` .
## `4NV+226+` .
## `4NV+39+` .
## `4NV+DR+` .
## `4NV+PD1+` .
## `4NV+PD-1+TIGIT-` .
## `4NV+PD-1+TIGIT+` .
## `4NV+PD-1-TIGIT-` .
## `4NV+PD-1-TIGIT+` .
## `4NV+TIGIT+` .
## `4ЕМ` .
## `4ЕМ_TH1` .
## `4ЕМ_TH17` .
## `4ЕМ_Th17TO1` .
## `4ЕМ_TH2` .
## `4ЕМ_TH22` .
## `4ЕМ+226+` .
## `4ЕМ+39+` .
## `4ЕМ+DR+` .
## `4ЕМ+PD1+` .
## `4ЕМ+PD1+TIGIT-` .
## `4ЕМ+PD1+TIGIT+` .
## `4ЕМ+PD1-TIGIT-` .
## `4ЕМ+PD1-TIGIT+` .
## `4ЕМ+TIGIT+` .
## `4ЕМTM` .
## `4СМ(СТАР2)` .
## `4СМ` .
## `4СМ_TH1` .
## `4СМ_TH17` .
## `4СМ_Th17TO1` .
## `4СМ_TH2` .
## `4СМ_TH22` .
## `4СМ+226+` .
## `4СМ+39+` .
## `4СМ+DR+` .
## `4СМ+PD1+` .
## `4СМ+PD1+TIGIT-` .
## `4СМ+PD1+TIGIT+` .
## `4СМ+PD1-TIGIT-` .
## `4СМ+PD1-TIGIT+` .
## `4СМ+TIGIT+` .
## `4ТM_TH1` .
## `4ТM_TH17` .
## `4ТM_Th17TO1` .
## `4ТM_TH2` .
## `4ТM_TH22` .
## `4ТREG(СТАР2)` .
## `4ТREG` .
## `4ТREG_TH1` .
## `4ТREG_TH17` .
## `4ТREG_Th17TO1` .
## `4ТREG_TH2` .
## `4ТREG_TH22` .
## `4ТЕ(СТАР2)` .
## `4ТЕ` .
## `4ТЕ_TH1` .
## `4ТЕ_TH17` .
## `4ТЕ_Th17TO1` .
## `4ТЕ_TH2` .
## `4ТЕ_TH22` .
## `4ТЕ+226+` .
## `4ТЕ+39+` .
## `4ТЕ+DR+` .
## `4ТЕ+PD-1+` .
## `4ТЕ+PD-1+TIGIT-` .
## `4ТЕ+PD-1+TIGIT+` .
## `4ТЕ+PD-1-TIGIT-` .
## `4ТЕ+PD-1-TIGIT+` .
## `4ТЕ+TIGIT+` .
## `4ТМ` .
## `8+ (IM STAT)` .
## `8+` .
## `8+226+` .
## `8+39+` .
## `8+DR+` .
## `8+PD-1+` .
## `8+PD-1+TIGIT-` .
## `8+PD-1+TIGIT+` .
## `8+PD-1-TIGIT-` .
## `8+PD-1-TIGIT+` .
## `8+TIGIT+` .
## `8EMTM` .
## `8EMTM+226+` .
## `8EMTM+39+` .
## `8EMTM+DR+` .
## `8EMTM+PD-1+` .
## `8EMTM+PD-1+TIGIT-` .
## `8EMTM+PD-1+TIGIT+` .
## `8EMTM+PD-1-TIGIT-` .
## `8EMTM+PD-1-TIGIT+` .
## `8EMTM+TIGIT+` .
## `8NV(СТАР2)` .
## `8NV` .
## `8NV+226+` .
## `8NV+39+` .
## `8NV+DR+` .
## `8NV+PD-1+` .
## `8NV+PD-1+TIGIT-` .
## `8NV+PD-1+TIGIT+` .
## `8NV+PD-1-TIGIT-` .
## `8NV+PD-1-TIGIT+` .
## `8NV+TIGIT+` .
## `8TREG` .
## `8ЕМ` .
## `8СМ(СТАР2)` .
## `8СМ` .
## `8СМ+226+` .
## `8СМ+39+` .
## `8СМ+DR+` .
## `8СМ+PD-1+` .
## `8СМ+PD-1+TIGIT-` .
## `8СМ+PD-1+TIGIT+` .
## `8СМ+PD-1-TIGIT-` .
## `8СМ+PD-1-TIGIT+` .
## `8СМ+TIGIT+` .
## `8ТЕ(СТАР2)` .
## `8ТЕ` .
## `8ТЕ+226+` .
## `8ТЕ+39+` .
## `8ТЕ+DR+` .
## `8ТЕ+PD-1+` .
## `8ТЕ+PD-1+TIGIT-` .
## `8ТЕ+PD-1+TIGIT+` .
## `8ТЕ+PD-1-TIGIT-` .
## `8ТЕ+PD-1-TIGIT+` .
## `8ТЕ+TIGIT+` .
## `8ТМ` .
## TREG_CM .
## TREG_EMTM .
## TREG_NV .
## TREG_TE .
## `TREG+226+` .
## `TREG+226+TIGIT-` .
## `TREG+226+TIGIT+` .
## `TREG+226-TIGIT-` .
## `TREG+226-TIGIT+` .
## `TREG+39+` .
## `TREG+DR+` .
## `TREG+PD-1+` .
## `TREG+TIGIT+` .
##несколько попыток отобрать предикторы в модель, везде aliased coefficient
model_90_filter <- glm(cGVHD_present ~ . - `4+ (IM STAT)` - `4+` - `4NV(СТАР2)` - `4NV` - `4ЕМ` - `4СМ(СТАР2)` - `4СМ` - `4ТREG(СТАР2)` - `4ТREG` - `4ТЕ(СТАР2)` - `4ТЕ` - `8+ (IM STAT)` - `8+` - `8EMTM` - `8NV(СТАР2)` - `8NV` - `8СМ(СТАР2)` - `8СМ` - `8ТЕ(СТАР2)` - `8ТЕ`, data = data_90, family = binomial)
summary(model_90_filter)
##
## Call:
## glm(formula = cGVHD_present ~ . - `4+ (IM STAT)` - `4+` - `4NV(СТАР2)` -
## `4NV` - `4ЕМ` - `4СМ(СТАР2)` - `4СМ` - `4ТREG(СТАР2)` -
## `4ТREG` - `4ТЕ(СТАР2)` - `4ТЕ` - `8+ (IM STAT)` -
## `8+` - `8EMTM` - `8NV(СТАР2)` - `8NV` - `8СМ(СТАР2)` -
## `8СМ` - `8ТЕ(СТАР2)` - `8ТЕ`, family = binomial,
## data = data_90)
##
## Coefficients: (78 not defined because of singularities)
## Estimate Std. Error z value Pr(>|z|)
## (Intercept) -2.776e+01 3.605e+05 0 1
## `4_TFH` -5.818e+00 8.031e+04 0 1
## `4_TH1` 2.656e+01 9.467e+05 0 1
## `4_TH17` -9.898e+01 1.504e+06 0 1
## `4_Th17TO1` -9.482e+01 5.141e+06 0 1
## `4_TH2` -7.014e+01 7.237e+05 0 1
## `4_TH22` -4.085e+00 4.450e+06 0 1
## `4+226+` 2.066e+01 1.107e+06 0 1
## `4+39+` 3.786e+01 9.003e+05 0 1
## `4+DR+` -7.175e+00 1.271e+05 0 1
## `4+PD-1+` 1.388e+09 7.014e+13 0 1
## `4+PD-1+TIGIT-` -1.388e+09 7.014e+13 0 1
## `4+PD-1+TIGIT+` -2.926e+09 3.248e+13 0 1
## `4+PD-1-TIGIT-` -2.752e+01 5.302e+05 0 1
## `4+PD-1-TIGIT+` -1.538e+09 8.709e+13 0 1
## `4+TIGIT+` 1.538e+09 8.709e+13 0 1
## `4NV_TH1` -8.685e+01 2.563e+06 0 1
## `4NV_TH17` 1.218e+02 1.464e+06 0 1
## `4NV_Th17TO1` 4.724e+02 1.482e+07 0 1
## `4NV_TH2` 7.191e+01 8.991e+05 0 1
## `4NV_TH22` -3.069e+02 1.039e+07 0 1
## `4NV+226+` -2.714e+01 1.126e+06 0 1
## `4NV+39+` 1.268e+01 2.072e+06 0 1
## `4NV+DR+` -2.711e+00 1.230e+06 0 1
## `4NV+PD1+` -1.076e+11 3.701e+15 0 1
## `4NV+PD-1+TIGIT-` 1.076e+11 3.701e+15 0 1
## `4NV+PD-1+TIGIT+` -2.395e+11 1.201e+16 0 1
## `4NV+PD-1-TIGIT-` 3.541e+01 5.552e+05 0 1
## `4NV+PD-1-TIGIT+` -3.471e+11 1.564e+16 0 1
## `4NV+TIGIT+` 3.471e+11 1.564e+16 0 1
## `4ЕМ_TH1` -4.077e+01 1.075e+06 0 1
## `4ЕМ_TH17` -1.992e+02 7.594e+06 0 1
## `4ЕМ_Th17TO1` 3.540e+02 6.738e+06 0 1
## `4ЕМ_TH2` 9.196e+01 1.220e+06 0 1
## `4ЕМ_TH22` 1.020e+03 9.990e+07 0 1
## `4ЕМ+226+` -3.620e+01 1.314e+06 0 1
## `4ЕМ+39+` -4.022e+01 8.473e+05 0 1
## `4ЕМ+DR+` 7.334e+00 3.289e+05 0 1
## `4ЕМ+PD1+` -3.490e+09 7.280e+13 0 1
## `4ЕМ+PD1+TIGIT-` 1.190e+09 1.597e+14 0 1
## `4ЕМ+PD1+TIGIT+` 1.519e+09 2.640e+14 0 1
## `4ЕМ+PD1-TIGIT-` -2.301e+09 1.057e+14 0 1
## `4ЕМ+PD1-TIGIT+` -1.972e+09 2.074e+14 0 1
## `4ЕМ+TIGIT+` -3.291e+08 1.137e+14 0 1
## `4ЕМTM` 2.301e+09 1.057e+14 0 1
## `4СМ_TH1` 1.176e+01 6.180e+05 0 1
## `4СМ_TH17` 1.031e+02 1.787e+06 0 1
## `4СМ_Th17TO1` 2.113e+01 2.776e+06 0 1
## `4СМ_TH2` 7.338e+01 7.548e+05 0 1
## `4СМ_TH22` 1.180e+02 1.024e+07 0 1
## `4СМ+226+` -4.553e+01 1.911e+06 0 1
## `4СМ+39+` -4.747e+01 1.396e+06 0 1
## `4СМ+DR+` -9.300e-01 2.872e+05 0 1
## `4СМ+PD1+` 6.314e+09 2.271e+14 0 1
## `4СМ+PD1+TIGIT-` -6.314e+09 2.271e+14 0 1
## `4СМ+PD1+TIGIT+` 2.295e+09 2.751e+14 0 1
## `4СМ+PD1-TIGIT-` 4.609e+01 1.600e+06 0 1
## `4СМ+PD1-TIGIT+` 8.609e+09 2.957e+14 0 1
## `4СМ+TIGIT+` -8.609e+09 2.957e+14 0 1
## `4ТM_TH1` -4.046e+01 1.141e+06 0 1
## `4ТM_TH17` 1.119e+02 1.767e+06 0 1
## `4ТM_Th17TO1` 1.064e+02 6.304e+06 0 1
## `4ТM_TH2` 6.166e+01 1.313e+06 0 1
## `4ТM_TH22` -2.066e+01 5.232e+06 0 1
## `4ТREG_TH1` 3.298e+02 8.226e+06 0 1
## `4ТREG_TH17` 9.210e+00 7.521e+05 0 1
## `4ТREG_Th17TO1` -5.297e+02 1.103e+07 0 1
## `4ТREG_TH2` NA NA NA NA
## `4ТREG_TH22` NA NA NA NA
## `4ТЕ_TH1` NA NA NA NA
## `4ТЕ_TH17` NA NA NA NA
## `4ТЕ_Th17TO1` NA NA NA NA
## `4ТЕ_TH2` NA NA NA NA
## `4ТЕ_TH22` NA NA NA NA
## `4ТЕ+226+` NA NA NA NA
## `4ТЕ+39+` NA NA NA NA
## `4ТЕ+DR+` NA NA NA NA
## `4ТЕ+PD-1+` NA NA NA NA
## `4ТЕ+PD-1+TIGIT-` NA NA NA NA
## `4ТЕ+PD-1+TIGIT+` NA NA NA NA
## `4ТЕ+PD-1-TIGIT-` NA NA NA NA
## `4ТЕ+PD-1-TIGIT+` NA NA NA NA
## `4ТЕ+TIGIT+` NA NA NA NA
## `4ТМ` NA NA NA NA
## `8+226+` NA NA NA NA
## `8+39+` NA NA NA NA
## `8+DR+` NA NA NA NA
## `8+PD-1+` NA NA NA NA
## `8+PD-1+TIGIT-` NA NA NA NA
## `8+PD-1+TIGIT+` NA NA NA NA
## `8+PD-1-TIGIT-` NA NA NA NA
## `8+PD-1-TIGIT+` NA NA NA NA
## `8+TIGIT+` NA NA NA NA
## `8EMTM+226+` NA NA NA NA
## `8EMTM+39+` NA NA NA NA
## `8EMTM+DR+` NA NA NA NA
## `8EMTM+PD-1+` NA NA NA NA
## `8EMTM+PD-1+TIGIT-` NA NA NA NA
## `8EMTM+PD-1+TIGIT+` NA NA NA NA
## `8EMTM+PD-1-TIGIT-` NA NA NA NA
## `8EMTM+PD-1-TIGIT+` NA NA NA NA
## `8EMTM+TIGIT+` NA NA NA NA
## `8NV+226+` NA NA NA NA
## `8NV+39+` NA NA NA NA
## `8NV+DR+` NA NA NA NA
## `8NV+PD-1+` NA NA NA NA
## `8NV+PD-1+TIGIT-` NA NA NA NA
## `8NV+PD-1+TIGIT+` NA NA NA NA
## `8NV+PD-1-TIGIT-` NA NA NA NA
## `8NV+PD-1-TIGIT+` NA NA NA NA
## `8NV+TIGIT+` NA NA NA NA
## `8TREG` NA NA NA NA
## `8ЕМ` NA NA NA NA
## `8СМ+226+` NA NA NA NA
## `8СМ+39+` NA NA NA NA
## `8СМ+DR+` NA NA NA NA
## `8СМ+PD-1+` NA NA NA NA
## `8СМ+PD-1+TIGIT-` NA NA NA NA
## `8СМ+PD-1+TIGIT+` NA NA NA NA
## `8СМ+PD-1-TIGIT-` NA NA NA NA
## `8СМ+PD-1-TIGIT+` NA NA NA NA
## `8СМ+TIGIT+` NA NA NA NA
## `8ТЕ+226+` NA NA NA NA
## `8ТЕ+39+` NA NA NA NA
## `8ТЕ+DR+` NA NA NA NA
## `8ТЕ+PD-1+` NA NA NA NA
## `8ТЕ+PD-1+TIGIT-` NA NA NA NA
## `8ТЕ+PD-1+TIGIT+` NA NA NA NA
## `8ТЕ+PD-1-TIGIT-` NA NA NA NA
## `8ТЕ+PD-1-TIGIT+` NA NA NA NA
## `8ТЕ+TIGIT+` NA NA NA NA
## `8ТМ` NA NA NA NA
## TREG_CM NA NA NA NA
## TREG_EMTM NA NA NA NA
## TREG_NV NA NA NA NA
## TREG_TE NA NA NA NA
## `TREG+226+` NA NA NA NA
## `TREG+226+TIGIT-` NA NA NA NA
## `TREG+226+TIGIT+` NA NA NA NA
## `TREG+226-TIGIT-` NA NA NA NA
## `TREG+226-TIGIT+` NA NA NA NA
## `TREG+39+` NA NA NA NA
## `TREG+DR+` NA NA NA NA
## `TREG+PD-1+` NA NA NA NA
## `TREG+TIGIT+` NA NA NA NA
##
## (Dispersion parameter for binomial family taken to be 1)
##
## Null deviance: 9.1068e+01 on 66 degrees of freedom
## Residual deviance: 3.8883e-10 on 0 degrees of freedom
## AIC: 134
##
## Number of Fisher Scoring iterations: 25
model_90_filter_2 <- glm(cGVHD_present ~ `4+ (IM STAT)` + `4NV(СТАР2)` + `4NV` + `4NV_TH17` + `4NV_Th17TO1` + `4NV_TH2` + `4NV+226+` + `4NV+PD-1-TIGIT-` + `4NV+TIGIT+` + `4ЕМ_TH1` + `4ЕМ_TH17` + `4ЕМ_Th17TO1` + `4СМ` + `4СМ_TH22` + `4ТЕ+PD-1+TIGIT-` + `8+ (IM STAT)` + `8+` + `8+DR+` + `8+PD-1+` + `8+PD-1+TIGIT+` + `8+TIGIT+` + `8EMTM` + `8EMTM+226+` + `8EMTM+39+` + `8EMTM+DR+` + `8EMTM+PD-1+` + `8EMTM+PD-1+TIGIT-` + `8EMTM+PD-1+TIGIT+` + `8EMTM+PD-1-TIGIT+` + `8EMTM+TIGIT+` + `8NV` + `8TREG` + `8ТЕ(СТАР2)` + `8ТЕ+226+` + `8ТЕ+DR+` + `8ТЕ+PD-1+` + `8ТЕ+PD-1+TIGIT+` + `8ТМ`, data = data_90, family = binomial)
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
model_90_filter_2 <- glm(cGVHD_present ~ `4NV_TH17` + `4NV_TH2` + `4NV+226+` + `4NV+PD-1-TIGIT-` + `4ЕМ_TH17` + `4ЕМ_Th17TO1` + `8+DR+` + `8+PD-1+` + `8+PD-1+TIGIT+` + `8EMTM+39+` + `8EMTM+DR+` + `8EMTM+PD-1+` + `8EMTM+PD-1+TIGIT-` + `8EMTM+TIGIT+` + `8NV` + `8TREG` + `8ТЕ+DR+` + `8ТЕ+PD-1+TIGIT+`, data = data_90, family = binomial)
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
summary(model_90_filter_2)
##
## Call:
## glm(formula = cGVHD_present ~ `4NV_TH17` + `4NV_TH2` + `4NV+226+` +
## `4NV+PD-1-TIGIT-` + `4ЕМ_TH17` + `4ЕМ_Th17TO1` + `8+DR+` +
## `8+PD-1+` + `8+PD-1+TIGIT+` + `8EMTM+39+` + `8EMTM+DR+` +
## `8EMTM+PD-1+` + `8EMTM+PD-1+TIGIT-` + `8EMTM+TIGIT+` + `8NV` +
## `8TREG` + `8ТЕ+DR+` + `8ТЕ+PD-1+TIGIT+`, family = binomial,
## data = data_90)
##
## Coefficients:
## Estimate Std. Error z value Pr(>|z|)
## (Intercept) -0.562595 0.674208 -0.834 0.4040
## `4NV_TH17` 0.600160 0.797564 0.752 0.4518
## `4NV_TH2` 0.191467 0.193999 0.987 0.3237
## `4NV+226+` -0.162948 0.213486 -0.763 0.4453
## `4NV+PD-1-TIGIT-` 0.155361 0.181271 0.857 0.3914
## `4ЕМ_TH17` -11.998866 9.866320 -1.216 0.2239
## `4ЕМ_Th17TO1` -5.845051 3.428431 -1.705 0.0882 .
## `8+DR+` -0.436723 0.224706 -1.944 0.0520 .
## `8+PD-1+` 0.007366 0.019088 0.386 0.6996
## `8+PD-1+TIGIT+` 0.794734 0.444771 1.787 0.0740 .
## `8EMTM+39+` -0.059645 0.050367 -1.184 0.2363
## `8EMTM+DR+` 0.486709 0.233585 2.084 0.0372 *
## `8EMTM+PD-1+` -0.979300 0.513995 -1.905 0.0567 .
## `8EMTM+PD-1+TIGIT-` 0.988064 0.584346 1.691 0.0909 .
## `8EMTM+TIGIT+` 0.096118 0.087828 1.094 0.2738
## `8NV` 0.010953 0.052602 0.208 0.8351
## `8TREG` -0.011642 0.008210 -1.418 0.1562
## `8ТЕ+DR+` 0.440618 0.228786 1.926 0.0541 .
## `8ТЕ+PD-1+TIGIT+` -0.798576 0.445109 -1.794 0.0728 .
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
##
## (Dispersion parameter for binomial family taken to be 1)
##
## Null deviance: 91.068 on 66 degrees of freedom
## Residual deviance: 58.630 on 48 degrees of freedom
## AIC: 96.63
##
## Number of Fisher Scoring iterations: 7
#Heat map
# Создание корреляционной матрицы
correlation_matrix <- cor(data_90_num, method = "spearman")
# Иерархическая кластеризация
cor_hclust <- hclust(dist((1-correlation_matrix)), method = "complete")
# Создание тепловой карты
pheatmap(
correlation_matrix,
cluster_rows = cor_hclust,
cluster_cols = cor_hclust,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица",
annotation_col = NULL,
annotation_row = NULL,
fontsize = 10
)
##кластеры
# Функция для расчета SSE
wss <- function(k) {
km <- kmeans(data_90_num, centers = k, nstart = 25)
return(km$tot.withinss)
}
# Расчет SSE для k от 1 до 10
k.values <- 1:10
SSE <- sapply(k.values, wss)
# Построение графика
plot(k.values, SSE, type = "b", xlab = "Число кластеров", ylab = "Сумма квадратов ошибок (SSE)",
main = "Метод локтя")
lines(k.values, SSE, col = "red")
library(cluster)
silhouette_scores <- sapply(2:10, function(k) {
km <- kmeans(data_90_num, centers = k, nstart = 25)
sil <- silhouette(km$cluster, dist(data_90_num))
mean(sil[, 3])
})
# Построение графика
plot(2:10, silhouette_scores, type = "b", xlab = "Число кластеров", ylab = "Средний силуэтный коэффициент",
main = "Критерий силуэта")
lines(2:10, silhouette_scores, col = "red")
#Деление на 10 кластеров + отдельные матрицы
clusters <- cutree(cor_hclust, k = 10)
table(clusters)
## clusters
## 1 2 3 4 5 6 7 8 9 10
## 29 27 14 13 9 9 38 9 6 10
cluster_1_vars <- names(which(clusters == 1))
cluster_2_vars <- names(which(clusters == 2))
cluster_3_vars <- names(which(clusters == 3))
cluster_4_vars <- names(which(clusters == 4))
cluster_5_vars <- names(which(clusters == 5))
cluster_6_vars <- names(which(clusters == 6))
cluster_7_vars <- names(which(clusters == 7))
cluster_8_vars <- names(which(clusters == 8))
cluster_9_vars <- names(which(clusters == 9))
cluster_10_vars <- names(which(clusters == 10))
cluster_1_matrix <- correlation_matrix[cluster_1_vars, cluster_1_vars]
pheatmap(
cluster_1_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для первого кластера"
)
cluster_2_matrix <- correlation_matrix[cluster_2_vars, cluster_2_vars]
pheatmap(
cluster_2_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для второго кластера"
)
cluster_3_matrix <- correlation_matrix[cluster_3_vars, cluster_3_vars]
pheatmap(
cluster_3_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для третьего кластера"
)
cluster_4_matrix <- correlation_matrix[cluster_4_vars, cluster_4_vars]
pheatmap(
cluster_4_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для четвертого кластера"
)
cluster_5_matrix <- correlation_matrix[cluster_5_vars, cluster_5_vars]
pheatmap(
cluster_5_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для пятого кластера"
)
cluster_6_matrix <- correlation_matrix[cluster_6_vars, cluster_6_vars]
pheatmap(
cluster_6_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для шестого кластера"
)
cluster_7_matrix <- correlation_matrix[cluster_7_vars, cluster_7_vars]
pheatmap(
cluster_7_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для седьмого кластера"
)
cluster_8_matrix <- correlation_matrix[cluster_8_vars, cluster_8_vars]
pheatmap(
cluster_8_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для восьмого кластера"
)
cluster_9_matrix <- correlation_matrix[cluster_9_vars, cluster_9_vars]
pheatmap(
cluster_9_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для девятого кластера"
)
cluster_10_matrix <- correlation_matrix[cluster_10_vars, cluster_10_vars]
pheatmap(
cluster_10_matrix,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для десятого кластера"
)
#Деление на 5 кластеров + корреляционные матрицы
clusters_2 <- cutree(cor_hclust, k = 5)
table(clusters_2)
## clusters_2
## 1 2 3 4 5
## 52 27 23 24 38
cluster_1 <- names(which(clusters_2 == 1))
cluster_2 <- names(which(clusters_2 == 2))
cluster_3 <- names(which(clusters_2 == 3))
cluster_4 <- names(which(clusters_2 == 4))
cluster_5 <- names(which(clusters_2 == 5))
cluster_matrix_1 <- correlation_matrix[cluster_1, cluster_1]
pheatmap(
cluster_matrix_1,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для первого кластера"
)
cluster_matrix_2 <- correlation_matrix[cluster_2, cluster_2]
pheatmap(
cluster_matrix_2,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для второго кластера"
)
cluster_matrix_3 <- correlation_matrix[cluster_3, cluster_3]
pheatmap(
cluster_matrix_3,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для третьего кластера"
)
cluster_matrix_4 <- correlation_matrix[cluster_4, cluster_4]
pheatmap(
cluster_matrix_4,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для четвертого кластера"
)
cluster_matrix_5 <- correlation_matrix[cluster_5, cluster_5]
pheatmap(
cluster_matrix_5,
cluster_rows = F,
cluster_cols = F,
color = colorRampPalette(c("blue", "white", "red"))(100),
main = "Корреляционная матрица для пятого кластера"
)
model_90_filter_finish <- glm(cGVHD_present ~ `4СМ_TH1` + `4_TH22`+ `TREG+PD-1+` + `4ЕМ_TH17` + `4ЕМ+39+` + `4ТREG_TH1` + `8ТЕ` + `4NV_TH2` + `TREG+226-TIGIT-` + `8NV+DR+` + `4NV+PD-1+TIGIT-` + `8EMTM+39+` + `8СМ+TIGIT+`, data = data_90, family = binomial)
summary(model_90_filter_finish)
##
## Call:
## glm(formula = cGVHD_present ~ `4СМ_TH1` + `4_TH22` + `TREG+PD-1+` +
## `4ЕМ_TH17` + `4ЕМ+39+` + `4ТREG_TH1` + `8ТЕ` + `4NV_TH2` +
## `TREG+226-TIGIT-` + `8NV+DR+` + `4NV+PD-1+TIGIT-` + `8EMTM+39+` +
## `8СМ+TIGIT+`, family = binomial, data = data_90)
##
## Coefficients:
## Estimate Std. Error z value Pr(>|z|)
## (Intercept) -0.700678 0.653080 -1.073 0.2833
## `4СМ_TH1` 0.200270 0.213659 0.937 0.3486
## `4_TH22` 0.199067 0.117592 1.693 0.0905 .
## `TREG+PD-1+` 0.085986 0.069854 1.231 0.2183
## `4ЕМ_TH17` -10.781745 11.975131 -0.900 0.3679
## `4ЕМ+39+` -0.039620 0.024450 -1.620 0.1051
## `4ТREG_TH1` 1.861241 1.718133 1.083 0.2787
## `8ТЕ` -0.002228 0.001679 -1.327 0.1845
## `4NV_TH2` 0.400092 0.175911 2.274 0.0229 *
## `TREG+226-TIGIT-` -0.890614 0.608079 -1.465 0.1430
## `8NV+DR+` -0.327920 0.166921 -1.965 0.0495 *
## `4NV+PD-1+TIGIT-` -0.251259 0.410354 -0.612 0.5403
## `8EMTM+39+` 0.026298 0.012307 2.137 0.0326 *
## `8СМ+TIGIT+` 0.025814 0.066322 0.389 0.6971
## ---
## Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
##
## (Dispersion parameter for binomial family taken to be 1)
##
## Null deviance: 91.068 on 66 degrees of freedom
## Residual deviance: 64.971 on 53 degrees of freedom
## AIC: 92.971
##
## Number of Fisher Scoring iterations: 7
##Корреляции в model_90_filter_finish
data_90_num_model <- data_90 %>%
select(`4СМ_TH1`, `4_TH22`,`TREG+PD-1+`, `4ЕМ_TH17`, `4ЕМ+39+`, `4ТREG_TH1`, `8ТЕ`, `4NV_TH2`, `TREG+226-TIGIT-`, `8NV+DR+`, `4NV+PD-1+TIGIT-`, `8EMTM+39+`, `8СМ+TIGIT+`)
data_90_num_model_cor <- cor(data_90_num_model)
corrplot(data_90_num_model_cor, method = "circle", type = "upper", tl.col = "black", tl.cex = 0.7)
corrplot(data_90_num_model_cor, method = 'number')
##Диагностика model_90_filter_finish 90 день
Проверка формы зависимости логита от \(X\) на линейность:
df_check <- model_90_filter_finish %>% broom::augment() %>%
dplyr::select(-starts_with("."), .fitted) %>%
dplyr::select(where(is.numeric)) %>%
pivot_longer(-.fitted) %>%
rename(logit = .fitted)
ggplot() +
geom_point(aes(x = value, y = logit), df_check) +
geom_smooth(aes(x = value, y = logit), df_check, color = "red", se = FALSE) +
facet_wrap(~ name, scales = "free") +
theme_bw()
## `geom_smooth()` using method = 'loess' and formula = 'y ~ x'
Мультиколлинеарность:
car::vif(model_90_filter_finish)
## `4СМ_TH1` `4_TH22` `TREG+PD-1+` `4ЕМ_TH17`
## 2.465438 1.849622 1.444725 1.581198
## `4ЕМ+39+` `4ТREG_TH1` `8ТЕ` `4NV_TH2`
## 2.088637 1.915383 2.578817 2.311035
## `TREG+226-TIGIT-` `8NV+DR+` `4NV+PD-1+TIGIT-` `8EMTM+39+`
## 2.353237 2.167347 1.463771 2.204821
## `8СМ+TIGIT+`
## 1.736319
Выбросы
resid_panel(model_90_filter_finish, plots = c("lev", "cookd"))
## Warning in helper_plotly_label(model): в результате преобразования созданы NA
## Warning in helper_plotly_label(model): в результате преобразования созданы NA
model_180_filter_finish <- glm(cGVHD_present ~ `4СМ_TH1` + `4_TH22`+ `TREG+PD-1+` + `4ЕМ_TH17` + `4ЕМ+39+` + `4ТREG_TH1` + `8ТЕ` + `4NV_TH2` + `4NV_Th17TO1` + `8NV+DR+` + `4NV+PD-1+TIGIT-` + `8EMTM+39+` + `8СМ+TIGIT+`, data = data_180, family = binomial)
summary(model_180_filter_finish)
##
## Call:
## glm(formula = cGVHD_present ~ `4СМ_TH1` + `4_TH22` + `TREG+PD-1+` +
## `4ЕМ_TH17` + `4ЕМ+39+` + `4ТREG_TH1` + `8ТЕ` + `4NV_TH2` +
## `4NV_Th17TO1` + `8NV+DR+` + `4NV+PD-1+TIGIT-` + `8EMTM+39+` +
## `8СМ+TIGIT+`, family = binomial, data = data_180)
##
## Coefficients:
## Estimate Std. Error z value Pr(>|z|)
## (Intercept) -1.1419914 1.0702854 -1.067 0.286
## `4СМ_TH1` 0.4745997 0.3242301 1.464 0.143
## `4_TH22` 0.1368453 0.1165034 1.175 0.240
## `TREG+PD-1+` 0.0362640 0.0585317 0.620 0.536
## `4ЕМ_TH17` 2.5650151 5.8451669 0.439 0.661
## `4ЕМ+39+` 0.0020392 0.0207330 0.098 0.922
## `4ТREG_TH1` -2.6278044 4.0082651 -0.656 0.512
## `8ТЕ` -0.0008452 0.0016178 -0.522 0.601
## `4NV_TH2` -0.1621211 0.1268905 -1.278 0.201
## `4NV_Th17TO1` 0.5616999 2.7822101 0.202 0.840
## `8NV+DR+` -0.1235626 0.1251563 -0.987 0.324
## `4NV+PD-1+TIGIT-` 0.0462197 0.1847806 0.250 0.802
## `8EMTM+39+` -0.0036416 0.0074200 -0.491 0.624
## `8СМ+TIGIT+` 0.0725012 0.0858565 0.844 0.398
##
## (Dispersion parameter for binomial family taken to be 1)
##
## Null deviance: 53.467 on 41 degrees of freedom
## Residual deviance: 37.070 on 28 degrees of freedom
## AIC: 65.07
##
## Number of Fisher Scoring iterations: 6
df_check <- model_180_filter_finish %>% broom::augment() %>%
dplyr::select(-starts_with("."), .fitted) %>%
dplyr::select(where(is.numeric)) %>%
pivot_longer(-.fitted) %>%
rename(logit = .fitted)
ggplot() +
geom_point(aes(x = value, y = logit), df_check) +
geom_smooth(aes(x = value, y = logit), df_check, color = "red", se = FALSE) +
facet_wrap(~ name, scales = "free") +
theme_bw()
## `geom_smooth()` using method = 'loess' and formula = 'y ~ x'
#Множественный регрессионный анализ, поправка на множественное сравнение, Forrest plot и Vulcano plot
# Копируем данные для переименования
data_90_copy <- data_90
# Функция для безопасных имен переменных
make_safe_names <- function(names) {
# Заменяем недопустимые символы на '_'
safe_names <- make.names(names, unique = TRUE)
return(safe_names)
}
# Функция для выполнения регрессии и коррекции p-значений
perform_multiple_regression <- function(data) {
# Находим числовые колонки, исключая целевую
numeric_cols <- names(data)[sapply(data, is.numeric) & names(data) != "cGVHD_present"]
# Создаем копию данных с безопасными именами
data_safe <- data
names(data_safe) <- make_safe_names(names(data))
# Обновляем список числовых колонок с безопасными именами
numeric_cols_safe <- make_safe_names(numeric_cols)
# Список для хранения результатов
regression_results <- list()
# Цикл по всем числовым переменным
for (i in seq_along(numeric_cols_safe)) {
col <- numeric_cols_safe[i]
original_col <- numeric_cols[i]
formula <- as.formula(paste("cGVHD_present ~", col))
model <- glm(formula, data = data_safe, family = binomial())
# Извлечение результатов
tidy_model <- tidy(model, conf.int = TRUE)
tidy_model$original_variable <- original_col
regression_results[[original_col]] <- tidy_model
}
# Коррекция p-значений методом Бенджамини-Хохберга
p_values <- sapply(regression_results, function(x) x$p.value[2])
adjusted_p_values <- p.adjust(p_values, method = "BH")
# Обновление результатов скорректированными p-значениями
for (i in seq_along(regression_results)) {
regression_results[[names(regression_results)[i]]]$p.adj <- adjusted_p_values[i]
}
return(regression_results)
}
# Выполнение регрессионного анализа
results <- perform_multiple_regression(data_90_copy)
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
## Warning: glm.fit: возникли подогнанные вероятности 0 или 1
# Подготовка данных для Forest Plot
forest_data <- do.call(rbind, lapply(names(results), function(col) {
res <- results[[col]]
data.frame(
variable = col,
estimate = res$estimate[2],
conf.low = res$conf.low[2],
conf.high = res$conf.high[2],
p.adj = res$p.adj[2]
)
}))
# Forest Plot
forest_plot_1 <- ggplot(forest_data, aes(y = reorder(variable, estimate), x = estimate)) +
geom_point(size = 3) +
geom_errorbarh(aes(xmin = conf.low, xmax = conf.high), height = 0.2) +
geom_vline(xintercept = 0, linetype = "dashed") +
theme_minimal() +
labs(title = "Forest Plot of Regression Coefficients",
x = "Coefficient Estimate",
y = "Variables") +
theme(axis.text.x = element_blank()) + #убрали текст с вертикальной оси после coord_flip()
scale_x_continuous(limits = c(-75, 25)) +
coord_flip()
forest_plot_2 <- ggplot(forest_data, aes(y = reorder(variable, estimate), x = estimate, color = p.adj < 0.05)) +
geom_point(size = 2) +
geom_errorbarh(aes(xmin = conf.low, xmax = conf.high), height = 0.1) +
geom_vline(xintercept = 0, linetype = "dashed") +
theme_minimal() +
labs(title = "Forest Plot of Regression Coefficients (p-adjust)",
x = "Coefficient Estimate",
y = "Variables") +
theme(axis.text.x = element_blank()) +
scale_x_continuous(limits = c(-75, 50)) +
coord_flip() +
scale_color_manual(values = c("TRUE" = "red", "FALSE" = "black"))
# Volcano Plot
volcano_plot_1 <- ggplot(forest_data, aes(x = estimate, y = -log10(p.adj))) +
geom_point(aes(color = p.adj < 0.05)) +
geom_text_repel(aes(label = variable),
box.padding = 0.5,
max.overlaps = Inf,
size = 2,
segment.size = 0.2,
segment.linetype = "solid",
segment.alpha = 0.5) + # Управляем толщиной линий
scale_color_manual(values = c("TRUE" = "red", "FALSE" = "black")) +
theme_minimal() +
labs(title = "Volcano Plot",
x = "Coefficient Estimate",
y = "-log10(Adjusted p-value)") +
scale_x_continuous(limits = c(-20, 8)) +
scale_y_continuous(limits = c(0, 0.18))
# Вывод результатов
print(forest_data)
## variable estimate conf.low conf.high
## 4_TFH 4_TFH -1.192789e-02 -0.053208193 2.624051e-02
## 4_TH1 4_TH1 -6.601313e-03 -0.029766044 3.009291e-03
## 4_TH17 4_TH17 -4.308347e-03 -0.059739379 4.966030e-02
## 4_Th17TO1 4_Th17TO1 2.286947e-02 -0.104923124 1.506918e-01
## 4_TH2 4_TH2 1.955833e-03 -0.030201781 3.313621e-02
## 4_TH22 4_TH22 2.880987e-02 -0.114728565 1.723961e-01
## 4+ (IM STAT) 4+ (IM STAT) 2.306123e-03 -0.005734818 1.087413e-02
## 4+ 4+ 3.052174e-03 -0.004529199 1.154683e-02
## 4+226+ 4+226+ -1.272667e-03 -0.006287738 2.261703e-03
## 4+39+ 4+39+ 7.264395e-04 -0.014854194 1.610321e-02
## 4+DR+ 4+DR+ -3.213373e-03 -0.011929145 1.353236e-03
## 4+PD-1+ 4+PD-1+ -2.169453e-03 -0.009020198 2.232934e-03
## 4+PD-1+TIGIT- 4+PD-1+TIGIT- -4.085288e-03 -0.016292979 6.297043e-03
## 4+PD-1+TIGIT+ 4+PD-1+TIGIT+ -3.446140e-03 -0.016352915 3.378383e-03
## 4+PD-1-TIGIT- 4+PD-1-TIGIT- 4.482373e-03 -0.008223370 1.747532e-02
## 4+PD-1-TIGIT+ 4+PD-1-TIGIT+ -1.456310e-02 -0.114348491 1.672480e-02
## 4+TIGIT+ 4+TIGIT+ -3.040573e-03 -0.014932729 2.816980e-03
## 4NV(СТАР2) 4NV(СТАР2) 2.946307e-02 0.003157308 6.032737e-02
## 4NV 4NV 2.931199e-02 0.004010783 5.954912e-02
## 4NV_TH1 4NV_TH1 2.607140e-01 -0.034348791 5.983811e-01
## 4NV_TH17 4NV_TH17 7.844828e-01 0.020829753 1.691711e+00
## 4NV_Th17TO1 4NV_Th17TO1 2.933089e+00 0.121140037 6.421601e+00
## 4NV_TH2 4NV_TH2 2.024009e-01 0.038313652 4.147739e-01
## 4NV_TH22 4NV_TH22 4.699992e+00 -0.533238620 1.102395e+01
## 4NV+226+ 4NV+226+ 3.406572e-02 0.003808529 6.984789e-02
## 4NV+39+ 4NV+39+ 3.264935e-01 -0.201775887 9.173007e-01
## 4NV+DR+ 4NV+DR+ -2.811586e-02 -0.242749162 1.519534e-01
## 4NV+PD1+ 4NV+PD1+ 6.997821e-02 -0.311046372 4.508367e-01
## 4NV+PD-1+TIGIT- 4NV+PD-1+TIGIT- 6.282884e-02 -0.448499366 5.643206e-01
## 4NV+PD-1+TIGIT+ 4NV+PD-1+TIGIT+ 2.583120e-01 -0.785509150 1.337379e+00
## 4NV+PD-1-TIGIT- 4NV+PD-1-TIGIT- 3.059930e-02 0.003400347 6.257681e-02
## 4NV+PD-1-TIGIT+ 4NV+PD-1-TIGIT+ 2.939970e-01 -0.419933981 1.122351e+00
## 4NV+TIGIT+ 4NV+TIGIT+ 2.120261e-01 -0.293119036 7.530865e-01
## 4ЕМ 4ЕМ -9.706025e-03 -0.044487015 1.930841e-03
## 4ЕМ_TH1 4ЕМ_TH1 -4.551469e-02 -0.160400164 4.438920e-03
## 4ЕМ_TH17 4ЕМ_TH17 -1.135250e+01 -33.830606874 -7.104417e-01
## 4ЕМ_Th17TO1 4ЕМ_Th17TO1 -5.644614e+00 -11.867157882 -1.471248e+00
## 4ЕМ_TH2 4ЕМ_TH2 -2.109105e-01 -1.011913703 3.109271e-02
## 4ЕМ_TH22 4ЕМ_TH22 -1.026784e+01 -41.521216241 1.044726e+01
## 4ЕМ+226+ 4ЕМ+226+ -3.986835e-03 -0.013845678 2.204190e-03
## 4ЕМ+39+ 4ЕМ+39+ -6.625632e-03 -0.034215574 1.989209e-02
## 4ЕМ+DR+ 4ЕМ+DR+ -5.474407e-03 -0.019228845 1.944977e-03
## 4ЕМ+PD1+ 4ЕМ+PD1+ -3.824117e-03 -0.014656994 2.990452e-03
## 4ЕМ+PD1+TIGIT- 4ЕМ+PD1+TIGIT- -6.301864e-03 -0.024186629 8.952337e-03
## 4ЕМ+PD1+TIGIT+ 4ЕМ+PD1+TIGIT+ -6.607567e-03 -0.029574105 4.371054e-03
## 4ЕМ+PD1-TIGIT- 4ЕМ+PD1-TIGIT- -1.566218e-02 -0.050425049 1.453703e-02
## 4ЕМ+PD1-TIGIT+ 4ЕМ+PD1-TIGIT+ -6.474996e-02 -0.350919775 3.146187e-02
## 4ЕМ+TIGIT+ 4ЕМ+TIGIT+ -6.276076e-03 -0.028181875 3.810628e-03
## 4ЕМTM 4ЕМTM -3.829029e-03 -0.013268465 2.213791e-03
## 4СМ(СТАР2) 4СМ(СТАР2) 6.453075e-03 -0.016663598 3.062525e-02
## 4СМ 4СМ 1.691211e-02 -0.004638123 4.056495e-02
## 4СМ_TH1 4СМ_TH1 2.942211e-03 -0.260373957 2.465506e-01
## 4СМ_TH17 4СМ_TH17 7.781370e-02 -0.025064358 1.880996e-01
## 4СМ_Th17TO1 4СМ_Th17TO1 4.089293e-01 -0.361590570 1.280204e+00
## 4СМ_TH2 4СМ_TH2 1.645319e-01 0.015139493 3.403715e-01
## 4СМ_TH22 4СМ_TH22 6.297697e-01 -0.064865270 1.424744e+00
## 4СМ+226+ 4СМ+226+ 7.529372e-03 -0.017057480 3.342749e-02
## 4СМ+39+ 4СМ+39+ 1.703792e-02 -0.028542819 6.416434e-02
## 4СМ+DR+ 4СМ+DR+ -8.241032e-03 -0.048732330 2.137218e-02
## 4СМ+PD1+ 4СМ+PD1+ 1.684060e-03 -0.029116091 3.146615e-02
## 4СМ+PD1+TIGIT- 4СМ+PD1+TIGIT- 7.812635e-03 -0.075864739 9.073960e-02
## 4СМ+PD1+TIGIT+ 4СМ+PD1+TIGIT+ 1.298687e-03 -0.041652816 4.169538e-02
## 4СМ+PD1-TIGIT- 4СМ+PD1-TIGIT- 3.707706e-02 -0.022283090 1.008015e-01
## 4СМ+PD1-TIGIT+ 4СМ+PD1-TIGIT+ -8.665034e-03 -0.333056389 2.823657e-01
## 4СМ+TIGIT+ 4СМ+TIGIT+ 9.266205e-04 -0.038311784 3.761018e-02
## 4ТM_TH1 4ТM_TH1 -9.890246e-03 -0.045154865 1.803704e-02
## 4ТM_TH17 4ТM_TH17 -8.974865e-02 -0.205328221 1.018344e-02
## 4ТM_Th17TO1 4ТM_Th17TO1 6.128490e-02 -0.120536423 2.541365e-01
## 4ТM_TH2 4ТM_TH2 3.326909e-02 -0.098463743 1.743657e-01
## 4ТM_TH22 4ТM_TH22 -5.450642e-03 -0.180917563 1.638927e-01
## 4ТREG(СТАР2) 4ТREG(СТАР2) 2.992617e-03 -0.004600390 1.140269e-02
## 4ТREG 4ТREG 9.974799e-02 -0.047338058 4.299644e-01
## 4ТREG_TH1 4ТREG_TH1 3.594778e-01 -1.730241399 2.429116e+00
## 4ТREG_TH17 4ТREG_TH17 7.377884e-02 -0.088605508 2.474507e-01
## 4ТREG_Th17TO1 4ТREG_Th17TO1 2.194209e+00 -2.110730531 6.882077e+00
## 4ТREG_TH2 4ТREG_TH2 1.697747e-01 -0.074402815 4.920320e-01
## 4ТREG_TH22 4ТREG_TH22 3.438166e-02 -0.226874367 2.932528e-01
## 4ТЕ(СТАР2) 4ТЕ(СТАР2) -8.666494e-03 -0.035327664 5.813436e-03
## 4ТЕ 4ТЕ -6.458256e-02 -0.179692196 1.563777e-03
## 4ТЕ_TH1 4ТЕ_TH1 -2.360022e-01 -0.703718076 -1.551099e-02
## 4ТЕ_TH17 4ТЕ_TH17 -7.299372e+00 -38.649479175 1.256012e+01
## 4ТЕ_Th17TO1 4ТЕ_Th17TO1 -1.774795e+01 -47.695632249 -2.146875e+00
## 4ТЕ_TH2 4ТЕ_TH2 -9.320401e-01 -4.039935135 1.086067e-01
## 4ТЕ_TH22 4ТЕ_TH22 -1.744097e+01 -69.999146488 2.468971e+01
## 4ТЕ+226+ 4ТЕ+226+ -9.094341e-03 -0.037043399 5.750676e-03
## 4ТЕ+39+ 4ТЕ+39+ 4.119643e-02 -0.052867455 1.435782e-01
## 4ТЕ+DR+ 4ТЕ+DR+ -1.088313e-02 -0.044530700 5.989214e-03
## 4ТЕ+PD-1+ 4ТЕ+PD-1+ -9.216858e-03 -0.040543357 9.699847e-03
## 4ТЕ+PD-1+TIGIT- 4ТЕ+PD-1+TIGIT- -1.818962e-02 -0.069199553 2.217053e-02
## 4ТЕ+PD-1+TIGIT+ 4ТЕ+PD-1+TIGIT+ -1.476146e-02 -0.082082005 1.697998e-02
## 4ТЕ+PD-1-TIGIT- 4ТЕ+PD-1-TIGIT- -4.504298e-02 -0.136808132 2.288264e-02
## 4ТЕ+PD-1-TIGIT+ 4ТЕ+PD-1-TIGIT+ -4.235761e-02 NA 3.792714e-02
## 4ТЕ+TIGIT+ 4ТЕ+TIGIT+ -1.177285e-02 -0.072042248 1.181967e-02
## 4ТМ 4ТМ -4.554485e-03 -0.016581118 6.621550e-03
## 8+ (IM STAT) 8+ (IM STAT) -8.047779e-04 -0.002256401 2.481918e-04
## 8+ 8+ -8.944099e-04 -0.002496242 2.313553e-04
## 8+226+ 8+226+ -8.073626e-04 -0.002101420 1.552208e-04
## 8+39+ 8+39+ -4.310858e-04 -0.006878449 5.114558e-03
## 8+DR+ 8+DR+ -6.945413e-04 -0.002101746 3.503550e-04
## 8+PD-1+ 8+PD-1+ -1.101171e-03 -0.003517477 6.643026e-04
## 8+PD-1+TIGIT- 8+PD-1+TIGIT- -3.644808e-03 -0.010843644 1.763569e-03
## 8+PD-1+TIGIT+ 8+PD-1+TIGIT+ -1.363957e-03 -0.004677822 1.068784e-03
## 8+PD-1-TIGIT- 8+PD-1-TIGIT- -2.301747e-03 -0.006480818 7.790071e-04
## 8+PD-1-TIGIT+ 8+PD-1-TIGIT+ -2.512063e-03 -0.006777948 3.856124e-04
## 8+TIGIT+ 8+TIGIT+ -1.065960e-03 -0.003003019 3.387724e-04
## 8EMTM 8EMTM -3.231769e-04 -0.004234766 2.900799e-03
## 8EMTM+226+ 8EMTM+226+ -4.047680e-04 -0.004571004 2.966600e-03
## 8EMTM+39+ 8EMTM+39+ 4.300058e-04 -0.015196125 1.477788e-02
## 8EMTM+DR+ 8EMTM+DR+ -1.139179e-04 -0.004205662 3.433143e-03
## 8EMTM+PD-1+ 8EMTM+PD-1+ 2.177711e-05 -0.006481992 5.891883e-03
## 8EMTM+PD-1+TIGIT- 8EMTM+PD-1+TIGIT- 9.189195e-04 -0.017978415 1.883762e-02
## 8EMTM+PD-1+TIGIT+ 8EMTM+PD-1+TIGIT+ -1.950759e-04 -0.009559274 8.179936e-03
## 8EMTM+PD-1-TIGIT- 8EMTM+PD-1-TIGIT- -1.496974e-03 -0.018576070 1.258540e-02
## 8EMTM+PD-1-TIGIT+ 8EMTM+PD-1-TIGIT+ -3.489338e-03 -0.020174930 8.028849e-03
## 8EMTM+TIGIT+ 8EMTM+TIGIT+ -7.032457e-04 -0.006781974 4.290054e-03
## 8NV(СТАР2) 8NV(СТАР2) 1.361576e-02 -0.031288953 5.944562e-02
## 8NV 8NV 3.849184e-02 -0.009713654 9.576209e-02
## 8NV+226+ 8NV+226+ 1.213997e-02 -0.037077835 6.187507e-02
## 8NV+39+ 8NV+39+ 8.379380e-02 -0.483143494 6.490125e-01
## 8NV+DR+ 8NV+DR+ -1.120911e-01 -0.334406160 3.887328e-02
## 8NV+PD-1+ 8NV+PD-1+ -2.042232e-01 -0.606927612 9.675565e-02
## 8NV+PD-1+TIGIT- 8NV+PD-1+TIGIT- -4.352068e-01 -1.520287462 2.999592e-01
## 8NV+PD-1+TIGIT+ 8NV+PD-1+TIGIT+ -2.866860e-01 -0.850054256 1.536046e-01
## 8NV+PD-1-TIGIT- 8NV+PD-1-TIGIT- 2.646975e-02 -0.023067033 8.053411e-02
## 8NV+PD-1-TIGIT+ 8NV+PD-1-TIGIT+ -1.908475e-01 -0.677642461 1.470535e-01
## 8NV+TIGIT+ 8NV+TIGIT+ -1.334034e-01 -0.416613832 7.339542e-02
## 8TREG 8TREG -8.475997e-04 -0.002415032 2.632552e-04
## 8ЕМ 8ЕМ -4.441537e-04 -0.004279948 2.626299e-03
## 8СМ(СТАР2) 8СМ(СТАР2) -1.105947e-02 -0.073664981 2.308438e-02
## 8СМ 8СМ 3.062386e-02 -0.024549124 1.195902e-01
## 8СМ+226+ 8СМ+226+ -1.280425e-02 -0.085594550 2.278949e-02
## 8СМ+39+ 8СМ+39+ 1.087545e-01 -0.174149816 4.149762e-01
## 8СМ+DR+ 8СМ+DR+ -1.523045e-02 -0.090736043 2.286988e-02
## 8СМ+PD-1+ 8СМ+PD-1+ -1.668810e-02 -0.124634528 6.114210e-02
## 8СМ+PD-1+TIGIT- 8СМ+PD-1+TIGIT- -7.915222e-02 -0.508316957 2.312430e-01
## 8СМ+PD-1+TIGIT+ 8СМ+PD-1+TIGIT+ -1.939491e-02 -0.161747057 8.132773e-02
## 8СМ+PD-1-TIGIT- 8СМ+PD-1-TIGIT- -1.876911e-02 -0.264661639 1.902866e-01
## 8СМ+PD-1-TIGIT+ 8СМ+PD-1-TIGIT+ -4.969508e-02 -0.394095492 3.928102e-02
## 8СМ+TIGIT+ 8СМ+TIGIT+ -1.699291e-02 -0.116894240 2.816586e-02
## 8ТЕ(СТАР2) 8ТЕ(СТАР2) -1.228451e-03 -0.002890620 7.762858e-06
## 8ТЕ 8ТЕ -1.642412e-03 -0.003730554 -1.551474e-04
## 8ТЕ+226+ 8ТЕ+226+ -1.318327e-03 -0.003085873 -1.576719e-05
## 8ТЕ+39+ 8ТЕ+39+ -1.280958e-03 -0.011644917 7.485492e-03
## 8ТЕ+DR+ 8ТЕ+DR+ -1.256611e-03 -0.003283363 2.311296e-04
## 8ТЕ+PD-1+ 8ТЕ+PD-1+ -2.052920e-03 -0.005812765 4.932080e-04
## 8ТЕ+PD-1+TIGIT- 8ТЕ+PD-1+TIGIT- -6.626415e-03 -0.017358858 9.545961e-04
## 8ТЕ+PD-1+TIGIT+ 8ТЕ+PD-1+TIGIT+ -2.475322e-03 -0.007600324 9.657084e-04
## 8ТЕ+PD-1-TIGIT- 8ТЕ+PD-1-TIGIT- -3.624402e-03 -0.009212732 3.529961e-04
## 8ТЕ+PD-1-TIGIT+ 8ТЕ+PD-1-TIGIT+ -3.607313e-03 -0.008909730 1.300236e-04
## 8ТЕ+TIGIT+ 8ТЕ+TIGIT+ -1.769967e-03 -0.004468783 1.750598e-04
## 8ТМ 8ТМ -6.597081e-04 -0.017889012 1.495558e-02
## TREG_CM TREG_CM 2.699803e-01 -0.060875348 8.322506e-01
## TREG_EMTM TREG_EMTM 1.963620e-02 -0.019606176 7.123463e-02
## TREG_NV TREG_NV 3.893276e-01 -0.176951123 9.853837e-01
## TREG_TE TREG_TE 1.417832e-01 -0.081908776 3.780830e-01
## TREG+226+ TREG+226+ 3.105693e-02 -0.016258837 9.091851e-02
## TREG+226+TIGIT- TREG+226+TIGIT- 1.520811e-01 -0.190878573 5.207239e-01
## TREG+226+TIGIT+ TREG+226+TIGIT+ 3.270098e-02 -0.018358487 1.002788e-01
## TREG+226-TIGIT- TREG+226-TIGIT- 4.902853e-02 -0.609246111 6.974801e-01
## TREG+226-TIGIT+ TREG+226-TIGIT+ 4.460158e-02 -0.049181155 1.734679e-01
## TREG+39+ TREG+39+ 1.934120e-02 -0.014326261 6.597026e-02
## TREG+DR+ TREG+DR+ 1.926575e-02 -0.016732736 6.872729e-02
## TREG+PD-1+ TREG+PD-1+ 4.150195e-02 -0.019923457 1.440264e-01
## TREG+TIGIT+ TREG+TIGIT+ 2.059914e-02 -0.013561723 6.793911e-02
## p.adj
## 4_TFH 0.7746926
## 4_TH1 0.7527201
## 4_TH17 0.9627693
## 4_Th17TO1 0.8772403
## 4_TH2 0.9627693
## 4_TH22 0.8626506
## 4+ (IM STAT) 0.7746926
## 4+ 0.7508243
## 4+226+ 0.7746926
## 4+39+ 0.9741645
## 4+DR+ 0.7508243
## 4+PD-1+ 0.7508243
## 4+PD-1+TIGIT- 0.7527201
## 4+PD-1+TIGIT+ 0.7508243
## 4+PD-1-TIGIT- 0.7746173
## 4+PD-1-TIGIT+ 0.7746926
## 4+TIGIT+ 0.7508243
## 4NV(СТАР2) 0.7508243
## 4NV 0.7508243
## 4NV_TH1 0.7508243
## 4NV_TH17 0.7508243
## 4NV_Th17TO1 0.7508243
## 4NV_TH2 0.7508243
## 4NV_TH22 0.7508243
## 4NV+226+ 0.7508243
## 4NV+39+ 0.7508243
## 4NV+DR+ 0.9141400
## 4NV+PD1+ 0.8772403
## 4NV+PD-1+TIGIT- 0.9262301
## 4NV+PD-1+TIGIT+ 0.8015183
## 4NV+PD-1-TIGIT- 0.7508243
## 4NV+PD-1-TIGIT+ 0.7508243
## 4NV+TIGIT+ 0.7508243
## 4ЕМ 0.7508243
## 4ЕМ_TH1 0.7508243
## 4ЕМ_TH17 0.7508243
## 4ЕМ_Th17TO1 0.7508243
## 4ЕМ_TH2 0.7746926
## 4ЕМ_TH22 0.7508243
## 4ЕМ+226+ 0.7508243
## 4ЕМ+39+ 0.8033715
## 4ЕМ+DR+ 0.7508243
## 4ЕМ+PD1+ 0.7508243
## 4ЕМ+PD1+TIGIT- 0.7508243
## 4ЕМ+PD1+TIGIT+ 0.7508243
## 4ЕМ+PD1-TIGIT- 0.7508243
## 4ЕМ+PD1-TIGIT+ 0.7746926
## 4ЕМ+TIGIT+ 0.7508243
## 4ЕМTM 0.7508243
## 4СМ(СТАР2) 0.7814361
## 4СМ 0.7508243
## 4СМ_TH1 0.9858508
## 4СМ_TH17 0.7508243
## 4СМ_Th17TO1 0.7508243
## 4СМ_TH2 0.7508243
## 4СМ_TH22 0.7508243
## 4СМ+226+ 0.7746926
## 4СМ+39+ 0.7527201
## 4СМ+DR+ 0.8015183
## 4СМ+PD1+ 0.9736931
## 4СМ+PD1+TIGIT- 0.9569874
## 4СМ+PD1+TIGIT+ 0.9741645
## 4СМ+PD1-TIGIT- 0.7508243
## 4СМ+PD1-TIGIT+ 0.9741645
## 4СМ+TIGIT+ 0.9741645
## 4ТM_TH1 0.7746926
## 4ТM_TH17 0.7508243
## 4ТM_Th17TO1 0.7746926
## 4ТM_TH2 0.8015183
## 4ТM_TH22 0.9741645
## 4ТREG(СТАР2) 0.7508243
## 4ТREG 0.7508243
## 4ТREG_TH1 0.8842108
## 4ТREG_TH17 0.7508243
## 4ТREG_Th17TO1 0.7508243
## 4ТREG_TH2 0.7508243
## 4ТREG_TH22 0.9144398
## 4ТЕ(СТАР2) 0.7508243
## 4ТЕ 0.7508243
## 4ТЕ_TH1 0.7508243
## 4ТЕ_TH17 0.7746926
## 4ТЕ_Th17TO1 0.7508243
## 4ТЕ_TH2 0.7508243
## 4ТЕ_TH22 0.7508243
## 4ТЕ+226+ 0.7508243
## 4ТЕ+39+ 0.7508243
## 4ТЕ+DR+ 0.7508243
## 4ТЕ+PD-1+ 0.7508243
## 4ТЕ+PD-1+TIGIT- 0.7508243
## 4ТЕ+PD-1+TIGIT+ 0.7727447
## 4ТЕ+PD-1-TIGIT- 0.7508243
## 4ТЕ+PD-1-TIGIT+ 0.7746926
## 4ТЕ+TIGIT+ 0.7746926
## 4ТМ 0.7508243
## 8+ (IM STAT) 0.7508243
## 8+ 0.7508243
## 8+226+ 0.7508243
## 8+39+ 0.9627693
## 8+DR+ 0.7508243
## 8+PD-1+ 0.7508243
## 8+PD-1+TIGIT- 0.7508243
## 8+PD-1+TIGIT+ 0.7508243
## 8+PD-1-TIGIT- 0.7508243
## 8+PD-1-TIGIT+ 0.7508243
## 8+TIGIT+ 0.7508243
## 8EMTM 0.9531593
## 8EMTM+226+ 0.9335033
## 8EMTM+39+ 0.9741645
## 8EMTM+DR+ 0.9741645
## 8EMTM+PD-1+ 0.9937872
## 8EMTM+PD-1+TIGIT- 0.9736931
## 8EMTM+PD-1+TIGIT+ 0.9741645
## 8EMTM+PD-1-TIGIT- 0.9501433
## 8EMTM+PD-1-TIGIT+ 0.7814361
## 8EMTM+TIGIT+ 0.9144398
## 8NV(СТАР2) 0.7746926
## 8NV 0.7508243
## 8NV+226+ 0.8015183
## 8NV+39+ 0.9141400
## 8NV+DR+ 0.7508243
## 8NV+PD-1+ 0.7508243
## 8NV+PD-1+TIGIT- 0.7508243
## 8NV+PD-1+TIGIT+ 0.7508243
## 8NV+PD-1-TIGIT- 0.7508243
## 8NV+PD-1-TIGIT+ 0.7508243
## 8NV+TIGIT+ 0.7508243
## 8TREG 0.7508243
## 8ЕМ 0.9144398
## 8СМ(СТАР2) 0.7814361
## 8СМ 0.7508243
## 8СМ+226+ 0.7746926
## 8СМ+39+ 0.7508243
## 8СМ+DR+ 0.7746926
## 8СМ+PD-1+ 0.8626506
## 8СМ+PD-1+TIGIT- 0.8116272
## 8СМ+PD-1+TIGIT+ 0.8772403
## 8СМ+PD-1-TIGIT- 0.9584098
## 8СМ+PD-1-TIGIT+ 0.7746926
## 8СМ+TIGIT+ 0.7746926
## 8ТЕ(СТАР2) 0.7508243
## 8ТЕ 0.7508243
## 8ТЕ+226+ 0.7508243
## 8ТЕ+39+ 0.9144398
## 8ТЕ+DR+ 0.7508243
## 8ТЕ+PD-1+ 0.7508243
## 8ТЕ+PD-1+TIGIT- 0.7508243
## 8ТЕ+PD-1+TIGIT+ 0.7508243
## 8ТЕ+PD-1-TIGIT- 0.7508243
## 8ТЕ+PD-1-TIGIT+ 0.7508243
## 8ТЕ+TIGIT+ 0.7508243
## 8ТМ 0.9741645
## TREG_CM 0.7508243
## TREG_EMTM 0.7508243
## TREG_NV 0.7508243
## TREG_TE 0.7508243
## TREG+226+ 0.7508243
## TREG+226+TIGIT- 0.7508243
## TREG+226+TIGIT+ 0.7508243
## TREG+226-TIGIT- 0.9627693
## TREG+226-TIGIT+ 0.7508243
## TREG+39+ 0.7508243
## TREG+DR+ 0.7508243
## TREG+PD-1+ 0.7508243
## TREG+TIGIT+ 0.7508243
forest_plot_1
## Warning: Removed 1 row containing missing values or values outside the scale range
## (`geom_errorbarh()`).
forest_plot_2
## Warning: Removed 1 row containing missing values or values outside the scale range
## (`geom_errorbarh()`).
volcano_plot_1
# Volcano Plot
volcano_plot_2 <- ggplot(forest_data, aes(x = estimate, y = -log10(p.adj))) +
# Добавляем прозрачность точкам через alpha
geom_point(aes(color = p.adj < 0.05), alpha = 0.5) +
# Добавляем условие для отображения подписей
geom_text_repel(data = subset(forest_data, estimate < -5 | estimate > 1),
aes(label = variable),
box.padding = 0.5,
max.overlaps = Inf,
size = 4,
segment.size = 0.2,
segment.linetype = "solid",
segment.alpha = 0.5) +
scale_color_manual(values = c("TRUE" = "red", "FALSE" = "black")) +
theme_minimal() +
labs(title = "Volcano Plot",
x = "Coefficient Estimate",
y = "-log10(Adjusted p-value)") +
scale_x_continuous(limits = c(-20, 8)) +
scale_y_continuous(limits = c(0, 0.18))
volcano_plot_2
volcano_plot_3 <- ggplot(forest_data, aes(x = estimate, y = -log10(p.adj))) +
# Добавляем логику для трех цветов на основе estimate
geom_point(aes(color = case_when(
estimate < -5 ~ "below_threshold",
estimate > 1 ~ "above_threshold",
TRUE ~ "within_threshold"
)),
size = 3,
alpha = 0.7) +
# Добавляем подписи для выбросов
geom_text_repel(data = subset(forest_data, estimate < -5 | estimate > 1),
aes(label = variable),
box.padding = 0.5,
max.overlaps = Inf,
size = 4,
segment.size = 0.2,
segment.linetype = "solid",
segment.alpha = 0.5) +
# Применяем цветовую палитру
scale_color_manual(
values = c(
"below_threshold" = "#304289", # Синий для точек ниже -5
"above_threshold" = "#893056", # Красный для точек выше 1
"within_threshold" = "#898889" # Серый для точек между порогами
),
guide = "none" # Убираем легенду
) +
theme_minimal() +
labs(title = "Volcano Plot",
x = "Coefficient Estimate",
y = "-log10(Adjusted p-value)") +
scale_x_continuous(limits = c(-20, 8)) +
scale_y_continuous(limits = c(0, 0.18))
volcano_plot_3